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Chronic Myeloid Leukemia Resource Center

News
09/20/2021
The increase in use of TKIs for patients with CML and the increase in TKI drug prices place considerable financial pressure on Medicare part-D insurers.
The increase in use of TKIs for patients with CML and the increase in TKI drug prices place considerable financial pressure on Medicare part-D insurers.
The increase in use of TKIs for...
09/20/2021
Journal of Clinical Pathways
Real-World Treatment Patterns, HCRU in Patients With CML Achieving Later Lines of Therapy
ENGAGING EXPERTS
01/14/2021
Ehab Atallah, MD, discusses results from a study evaluating treatment patterns in patients with CML achieving later lines of therapy, and estimating the associated HCRU and costs.
Ehab Atallah, MD, discusses results from a study evaluating treatment patterns in patients with CML achieving later lines of therapy, and estimating the associated HCRU and costs.
Ehab Atallah, MD, discusses...
01/14/2021
Journal of Clinical Pathways
Conference Coverage
12/05/2020
For patients with CML, switching to the subsequent lines of therapy is frequent due to previous TKI intolerance and results in high medical costs.
For patients with CML, switching to the subsequent lines of therapy is frequent due to previous TKI intolerance and results in high medical costs.
For patients with CML, switching...
12/05/2020
Journal of Clinical Pathways
Economic Burden of CML Treatment in the US: Before and After the Availability of Generic Imatinib
ENGAGING EXPERTS
10/03/2020
Gary Lyman, MD, discusses a project exploring the cost of TKIs, particularly imatinib and generic imatinib, for the treatment of patients with CML.
Gary Lyman, MD, discusses a project exploring the cost of TKIs, particularly imatinib and generic imatinib, for the treatment of patients with CML.
Gary Lyman, MD, discusses a...
10/03/2020
Journal of Clinical Pathways
Trend in TKI Use, Adherence, and Switching Patterns in Patients With CML: Before and After the Availability of Generic Imatinib
Research Reports
08/19/2020
Gary H. Lyman, MD, MPH, FASCO, FRCP, FACP; David R. Doody, MS; Shasank Chennupati, PharmD, MPH; Eric J. Chow, MD, MPH; Lena E. Winestone, MD, MSHP; Henry J. Henk, PhD; Pamela Morin, MBA; Jennifer J. Wilkes, MD, MSCE
Abstract: The therapeutic landscape for chronic myeloid leukemia (CML) has evolved substantially over the past decade, most notably with the introduction of second- and third-generation tyrosine kinase inhibitors...
Abstract: The therapeutic landscape for chronic myeloid leukemia (CML) has evolved substantially over the past decade, most notably with the introduction of second- and third-generation tyrosine kinase inhibitors...
...
08/19/2020
Journal of Clinical Pathways
Research in Review
08/02/2017
Patients with chronic myeloid leukemia (CML) in the chronic phase may achieve molecular response with safe and effective treatment dose escalation, according to a recent study. ----- Related Content CML Mutations...
Patients with chronic myeloid leukemia (CML) in the chronic phase may achieve molecular response with safe and effective treatment dose escalation, according to a recent study. ----- Related Content CML Mutations...
...
08/02/2017
Journal of Clinical Pathways
Research in Review
07/27/2017
Cardiovascular disease rates and its associated risks are increased in patients with chronic myelogenous leukemia (CML) treated by community-based oncologists and should impact treatment decisions, according to a...
Cardiovascular disease rates and its associated risks are increased in patients with chronic myelogenous leukemia (CML) treated by community-based oncologists and should impact treatment decisions, according to a...
...
07/27/2017
Journal of Clinical Pathways
Research in Review
07/27/2017
Patients with chronic myeloid leukemia (CML) who attempt to discontinue tyrosine kinase inhibitor (TKI) therapy for a second time after a first unsuccessful attempt have strong treatment-free remission rates,...
Patients with chronic myeloid leukemia (CML) who attempt to discontinue tyrosine kinase inhibitor (TKI) therapy for a second time after a first unsuccessful attempt have strong treatment-free remission rates,...
...
07/27/2017
Journal of Clinical Pathways

Expert Insights

Real-World Treatment Patterns, HCRU in Patients With CML Achieving Later Lines of Therapy
ENGAGING EXPERTS
01/14/2021
Ehab Atallah, MD, discusses results from a study evaluating treatment patterns in patients with CML achieving later lines of therapy, and estimating the associated HCRU and costs.
Ehab Atallah, MD, discusses results from a study evaluating treatment patterns in patients with CML achieving later lines of therapy, and estimating the associated HCRU and costs.
Ehab Atallah, MD, discusses...
01/14/2021
Journal of Clinical Pathways
Economic Burden of CML Treatment in the US: Before and After the Availability of Generic Imatinib
ENGAGING EXPERTS
10/03/2020
Gary Lyman, MD, discusses a project exploring the cost of TKIs, particularly imatinib and generic imatinib, for the treatment of patients with CML.
Gary Lyman, MD, discusses a project exploring the cost of TKIs, particularly imatinib and generic imatinib, for the treatment of patients with CML.
Gary Lyman, MD, discusses a...
10/03/2020
Journal of Clinical Pathways
Headshots
Interview
09/17/2025
Mengmeng Du, ScD, MSc; Noah C. Peeri, PhD, MPH
In this interview, guest cancer epidemiologists share their findings on endometrial cancer risk in younger women, highlighting the powerful role of obesity and metabolic health, shared risk patterns across age groups, and the importance of...
In this interview, guest cancer epidemiologists share their findings on endometrial cancer risk in younger women, highlighting the powerful role of obesity and metabolic health, shared risk patterns across age groups, and the importance of...
In this interview, guest cancer...
09/17/2025
Journal of Clinical Pathways
BDHC thumbnail
Videos
09/16/2025
John Hennessy, MBA; Michael Kolodziej, MD
In this episode of Breaking Down Health Care, John Hennessy and Dr Michael Kolodziej explore the many dimensions of second opinions in oncology—ranging from in-practice consultations to academic referrals, payer-sponsored programs, and...
In this episode of Breaking Down Health Care, John Hennessy and Dr Michael Kolodziej explore the many dimensions of second opinions in oncology—ranging from in-practice consultations to academic referrals, payer-sponsored programs, and...
In this episode of Breaking Down...
09/16/2025
Cancer Care Business Exchange
Golla Headshot
Videos
09/10/2025
Vishnukamal Golla, MD, MPH
In this discussion, Dr Kamal Golla, vice president of clinical technology and performance at Evolent Health, shares how the Predictable Cost of Care model shifts the focus from drug acquisition costs to a comprehensive view of total care...
In this discussion, Dr Kamal Golla, vice president of clinical technology and performance at Evolent Health, shares how the Predictable Cost of Care model shifts the focus from drug acquisition costs to a comprehensive view of total care...
In this discussion, Dr Kamal...
09/10/2025
Journal of Clinical Pathways
Thawani Headshot
Videos
08/28/2025
Rajat Thawani, MD
Rajat Thawani, MD, shares key insights on balancing progression-free and overall survival, the expanding role of biomarker testing, and the promise of multi-omic data integration in reshaping NSCLC treatment.
Rajat Thawani, MD, shares key insights on balancing progression-free and overall survival, the expanding role of biomarker testing, and the promise of multi-omic data integration in reshaping NSCLC treatment.
Rajat Thawani, MD, shares key...
08/28/2025
Journal of Clinical Pathways
Blog
08/27/2025
The 2025 Clinical Pathways Congress + Cancer Care Business Exchange (CPC+CBEx), to be held September 5-6 in Boston, will confront these challenges head-on through 13 powerful abstracts that demonstrate what it takes to translate evidence into...
The 2025 Clinical Pathways Congress + Cancer Care Business Exchange (CPC+CBEx), to be held September 5-6 in Boston, will confront these challenges head-on through 13 powerful abstracts that demonstrate what it takes to translate evidence into...
The 2025 Clinical Pathways...
08/27/2025
Journal of Clinical Pathways
Wilfong Headshot
Videos
08/20/2025
Lalan Wilfong, MD
The Predictable Cost of Care Working Group (the PCC) is a multi-organizational effort comprised of pharmaceutical and biotech manufacturers, pathway vendor organizations, community practices, IDNs, and payers. The purpose of the PCC is to...
The Predictable Cost of Care Working Group (the PCC) is a multi-organizational effort comprised of pharmaceutical and biotech manufacturers, pathway vendor organizations, community practices, IDNs, and payers. The purpose of the PCC is to...
The Predictable Cost of Care...
08/20/2025
Journal of Clinical Pathways
ONLINE EXCLUSIVES
08/15/2025
Jason Hafron, MD
Jason Hafron, MD, discusses how Solaris Health developed and implemented standardized, National Comprehensive Cancer Network (NCCN)-based prostate cancer pathways across its national network to ensure consistent, high-quality care, streamline...
Jason Hafron, MD, discusses how Solaris Health developed and implemented standardized, National Comprehensive Cancer Network (NCCN)-based prostate cancer pathways across its national network to ensure consistent, high-quality care, streamline...
Jason Hafron, MD, discusses how...
08/15/2025
Journal of Clinical Pathways
Jennifer Woyach, MD
Interview
08/13/2025
Jennifer Ann Woyach, MD
This expert interview explores how emerging resistance mechanisms to Bruton tyrosine kinase (BTK) and BCL2 inhibitors are reshaping personalized treatment strategies and diagnostic workflows in chronic lymphocytic leukemia (CLL).
This expert interview explores how emerging resistance mechanisms to Bruton tyrosine kinase (BTK) and BCL2 inhibitors are reshaping personalized treatment strategies and diagnostic workflows in chronic lymphocytic leukemia (CLL).
This expert interview explores...
08/13/2025
Journal of Clinical Pathways
Henschel
Videos
08/13/2025
Rhonda Henschel, MBA
The Predictable Cost of Care Working Group (the PCC) is a multi-organizational effort comprised of pharmaceutical and biotech manufacturers, pathway vendor organizations, community practices, IDNs, and payers. The purpose of the PCC is to...
The Predictable Cost of Care Working Group (the PCC) is a multi-organizational effort comprised of pharmaceutical and biotech manufacturers, pathway vendor organizations, community practices, IDNs, and payers. The purpose of the PCC is to...
The Predictable Cost of Care...
08/13/2025
Journal of Clinical Pathways
Arrowsmith Headshot
Videos
08/08/2025
Edward Arrowsmith, MD
The Predictable Cost of Care Working Group (the PCC) is a multi-organizational effort comprised of pharmaceutical and biotech manufacturers, pathway vendor organizations, community practices, IDNs, and payers. The purpose of the PCC is to...
The Predictable Cost of Care Working Group (the PCC) is a multi-organizational effort comprised of pharmaceutical and biotech manufacturers, pathway vendor organizations, community practices, IDNs, and payers. The purpose of the PCC is to...
The Predictable Cost of Care...
08/08/2025
Journal of Clinical Pathways

Newsfeed

News
09/20/2021
The increase in use of TKIs for patients with CML and the increase in TKI drug prices place considerable financial pressure on Medicare part-D insurers.
The increase in use of TKIs for patients with CML and the increase in TKI drug prices place considerable financial pressure on Medicare part-D insurers.
The increase in use of TKIs for...
09/20/2021
Journal of Clinical Pathways
Conference Coverage
12/05/2020
For patients with CML, switching to the subsequent lines of therapy is frequent due to previous TKI intolerance and results in high medical costs.
For patients with CML, switching to the subsequent lines of therapy is frequent due to previous TKI intolerance and results in high medical costs.
For patients with CML, switching...
12/05/2020
Journal of Clinical Pathways
News
09/26/2025
Grace Taylor, MS, MA
A sweeping new US Department of Health and Human Services (HHS) rule taking effect October 1 will give doctors and patients real-time access to drug costs and prior authorization decisions.
A sweeping new US Department of Health and Human Services (HHS) rule taking effect October 1 will give doctors and patients real-time access to drug costs and prior authorization decisions.
A sweeping new US Department of...
09/26/2025
Journal of Clinical Pathways
Conference Coverage
09/10/2025
Grace Taylor, MS, MA
In this CPC+CBEx session, experts debate how real-world evidence can complement clinical trials, accelerate regulatory approvals, and reshape patient care.
In this CPC+CBEx session, experts debate how real-world evidence can complement clinical trials, accelerate regulatory approvals, and reshape patient care.
In this CPC+CBEx session,...
09/10/2025
Journal of Clinical Pathways
Conference Coverage
09/10/2025
Hannah Musick
The Predictable Cost of Care initiative is creating a transparent, standardized model to quantify the true, incremental costs of cancer therapies—enabling more informed, equitable, and efficient decision-making across pathways, payers, and...
The Predictable Cost of Care initiative is creating a transparent, standardized model to quantify the true, incremental costs of cancer therapies—enabling more informed, equitable, and efficient decision-making across pathways, payers, and...
The Predictable Cost of Care...
09/10/2025
Journal of Clinical Pathways
Conference Coverage
09/09/2025
Hannah Musick
A decade after the American Society of Clinical Oncology’s (ASCO’s) original guidance, oncology pathways are maturing into powerful tools for standardizing care, but gaps in disease coverage, workflow integration, and real-time adaptability...
A decade after the American Society of Clinical Oncology’s (ASCO’s) original guidance, oncology pathways are maturing into powerful tools for standardizing care, but gaps in disease coverage, workflow integration, and real-time adaptability...
A decade after the American...
09/09/2025
Journal of Clinical Pathways
Conference Coverage
09/09/2025
Grace Taylor, MS, MA
In this panel from CPC+CBEx, experts explore how artificial intelligence (AI) is emerging as a “thought partner” in health care, helping clinicians and practices manage rising complexity and improve outcomes while preserving the human touch...
In this panel from CPC+CBEx, experts explore how artificial intelligence (AI) is emerging as a “thought partner” in health care, helping clinicians and practices manage rising complexity and improve outcomes while preserving the human touch...
In this panel from CPC+CBEx,...
09/09/2025
Journal of Clinical Pathways
Conference Coverage
09/09/2025
Grace Taylor, MS, MA
From streamlining documentation to reshaping prior authorization, a panel of experts reveal how artificial intelligence (AI) is changing the realities of cancer care—and the challenges that come with it.
From streamlining documentation to reshaping prior authorization, a panel of experts reveal how artificial intelligence (AI) is changing the realities of cancer care—and the challenges that come with it.
From streamlining documentation...
09/09/2025
Journal of Clinical Pathways
Conference Coverage
09/08/2025
Grace Taylor, MS, MA
This session highlights how pharmacists are stepping into pivotal leadership roles, balancing science, business, and patient care to navigate the increasingly complex oncology treatment landscape.
This session highlights how pharmacists are stepping into pivotal leadership roles, balancing science, business, and patient care to navigate the increasingly complex oncology treatment landscape.
This session highlights how...
09/08/2025
Journal of Clinical Pathways
Conference Coverage
09/08/2025
Hannah Musick
Theranostics is rapidly emerging as a transformative, fifth pillar of cancer care—combining precision imaging and targeted radiopharmaceutical therapy—but its widespread adoption hinges on overcoming operational, financial, and infrastructure...
Theranostics is rapidly emerging as a transformative, fifth pillar of cancer care—combining precision imaging and targeted radiopharmaceutical therapy—but its widespread adoption hinges on overcoming operational, financial, and infrastructure...
Theranostics is rapidly emerging...
09/08/2025
Journal of Clinical Pathways
Conference Coverage
09/08/2025
Hannah Musick
A panel of oncology leaders urged community practices to take immediate, systematized steps to adopt bispecifics and CAR T-cell therapies—highlighting that without local access, the promise of these innovations may never reach the patients...
A panel of oncology leaders urged community practices to take immediate, systematized steps to adopt bispecifics and CAR T-cell therapies—highlighting that without local access, the promise of these innovations may never reach the patients...
A panel of oncology leaders...
09/08/2025
Journal of Clinical Pathways
Conference Coverage
09/08/2025
Juliet Gallagher
A session at CPC+CBEx 2025 highlighted how structured triage, real-time care coordination, and non-clinical staff training can transform symptom management and reduce unnecessary acute care utilization in oncology.
A session at CPC+CBEx 2025 highlighted how structured triage, real-time care coordination, and non-clinical staff training can transform symptom management and reduce unnecessary acute care utilization in oncology.
A session at CPC+CBEx 2025...
09/08/2025
Journal of Clinical Pathways

Interactive Features

Quiz
09/18/2025
Learn more about the Predictable Cost of Care (PCOC) model and its applications in value-based care.
Learn more about the Predictable Cost of Care (PCOC) model and its applications in value-based care.
Learn more about the Predictable...
09/18/2025
Journal of Clinical Pathways
Quiz
08/27/2025
The National Comprehensive Cancer Network (NCCN) Guidelines Navigator is a new interactive digital platform that delivers evidence-based oncology recommendations and is currently available for all 88 NCCN guideline sets.
The National Comprehensive Cancer Network (NCCN) Guidelines Navigator is a new interactive digital platform that delivers evidence-based oncology recommendations and is currently available for all 88 NCCN guideline sets.
The National Comprehensive...
08/27/2025
Journal of Clinical Pathways
Quiz
08/12/2025
Between 2018 and 2023, which of the following trends was observed in the delivery of specialty palliative care (PC) among Medicare beneficiaries with poor-prognosis cancers?
Between 2018 and 2023, which of the following trends was observed in the delivery of specialty palliative care (PC) among Medicare beneficiaries with poor-prognosis cancers?
Between 2018 and 2023, which of...
08/12/2025
Journal of Clinical Pathways
Quiz
07/30/2025
Learn more about how clinical pathways are helping multidisciplinary teams standardize cancer care, reduce costs, and improve outcomes—and why aligning them with evidence-based guidelines is essential in today’s value-based healthcare...
Learn more about how clinical pathways are helping multidisciplinary teams standardize cancer care, reduce costs, and improve outcomes—and why aligning them with evidence-based guidelines is essential in today’s value-based healthcare...
Learn more about how clinical...
07/30/2025
Journal of Clinical Pathways
SPONSORED QUIZ BY SANOFI
11/28/2022
  Indication SARCLISA (isatuximab-irfc) is indicated: In combination with carfilzomib and dexamethasone, for the treatment of adult patients with relapsed or refractory multiple myeloma who have received 1 to 3 prior lines of...
  Indication SARCLISA (isatuximab-irfc) is indicated: In combination with carfilzomib and dexamethasone, for the treatment of adult patients with relapsed or refractory multiple myeloma who have received 1 to 3 prior lines of...
  Indication SARCLISA...
11/28/2022
Journal of Clinical Pathways
Quiz
07/26/2022
True or False: Medicaid beneficiaries with advanced non-small cell lung cancer were less likely to receive biomarker testing and biomarker-driven therapies compared to those with commercial insurance.
True or False: Medicaid beneficiaries with advanced non-small cell lung cancer were less likely to receive biomarker testing and biomarker-driven therapies compared to those with commercial insurance.
True or False: Medicaid...
07/26/2022
Journal of Clinical Pathways
Quiz
07/14/2022
True or False: Among daratumumab, lenalidomide, and dexamethasone triple therapy (DRd); bortezomib and lenalidomide plus dexamethasone triple therapy (VRd); and Rd, the most cost-effective treatment regimen in patients with newly diagnosed...
True or False: Among daratumumab, lenalidomide, and dexamethasone triple therapy (DRd); bortezomib and lenalidomide plus dexamethasone triple therapy (VRd); and Rd, the most cost-effective treatment regimen in patients with newly diagnosed...
True or False: Among...
07/14/2022
Journal of Clinical Pathways
Quiz
07/12/2022
True or False: About 34% of commercially insured patients with ovarian cancer receive germline BRCA testing.
True or False: About 34% of commercially insured patients with ovarian cancer receive germline BRCA testing.
True or False: About 34% of...
07/12/2022
Journal of Clinical Pathways
Quiz
06/30/2022
True or False: Under a willingness-to-pay threshold of $100,000 per quality-adjusted life year, margetuximab plus chemotherapy is cost-effective compared to trastuzumab plus chemotherapy for patients with ERBB2–positive, advanced breast...
True or False: Under a willingness-to-pay threshold of $100,000 per quality-adjusted life year, margetuximab plus chemotherapy is cost-effective compared to trastuzumab plus chemotherapy for patients with ERBB2–positive, advanced breast...
True or False: Under a...
06/30/2022
Journal of Clinical Pathways
Quiz
06/28/2022
True or False: Bendamustine and rituximab was the most used frontline regimen for the treatment of MCL, while BTK inhibitors were the most used agents in later lines of therapy.
True or False: Bendamustine and rituximab was the most used frontline regimen for the treatment of MCL, while BTK inhibitors were the most used agents in later lines of therapy.
True or False: Bendamustine and...
06/28/2022
Journal of Clinical Pathways