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Journal of Critical Limb Ischemia

Explore the Journal of Critical Limb Ischemia (JCLI), a quarterly international peer-reviewed journal and online clinical resource for those treating chronic limb-threatening ischemia. JCLI is the official journal of the CLI Global Society.

Recently Published

jcli top 5
Feature
01/20/2026
Isabel Vega
The Journal of Critical Limb Ischemia looks back at the most popular articles of the year
The Journal of Critical Limb Ischemia looks back at the most popular articles of the year
The Journal of Critical Limb...
01/20/2026
Journal of Critical Limb Ischemia
Radiation Safety
01/08/2026
First-of-its-Kind, Multi-Specialty Clinical Initiative Across IC, EP, Endovascular, Aortic, and Neurovascular
First-of-its-Kind, Multi-Specialty Clinical Initiative Across IC, EP, Endovascular, Aortic, and Neurovascular
First-of-its-Kind,...
01/08/2026
Journal of Critical Limb Ischemia
Case Report
11/26/2025
Karthikeshwar Kasirajan, MD
This case report describes 2 different techniques for using percutaneous bypass in patients with prior SFA stent occlusions extending to the common femoral bifurcation.
This case report describes 2 different techniques for using percutaneous bypass in patients with prior SFA stent occlusions extending to the common femoral bifurcation.
This case report describes 2...
11/26/2025
Journal of Critical Limb Ischemia
Dr van den Berg
AMP 2025
08/14/2025
Jos C. van den Berg, MD, PhD
At AMP 2025, Interventional radiologist Jos van den Berg, MD, PhD, from the Clinica Luganese Moncucco in Lugano, Switzerland, delivered a presentation titled “The Economic Burden of CLTI in Europe.”
At AMP 2025, Interventional radiologist Jos van den Berg, MD, PhD, from the Clinica Luganese Moncucco in Lugano, Switzerland, delivered a presentation titled “The Economic Burden of CLTI in Europe.”
At AMP 2025, Interventional...
08/14/2025
Journal of Critical Limb Ischemia
DR NEVILLE
AMP 2025
08/14/2025
Richard Neville, MD
Richard Neville, MD, outlines how CLTI programs are redefining “quality.” The era of anecdotal morbidity and mortality reviews has given way to continuous, data-driven evaluation aligned with value-based care.
Richard Neville, MD, outlines how CLTI programs are redefining “quality.” The era of anecdotal morbidity and mortality reviews has given way to continuous, data-driven evaluation aligned with value-based care.
Richard Neville, MD, outlines...
08/14/2025
Journal of Critical Limb Ischemia
Editorial/Commentary
07/23/2025
Marta Lobato, MD; August Ysa, MD, EBVS
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the...
07/23/2025
Journal of Critical Limb Ischemia
Original Contribution
07/08/2025
Arnaud Kerzmann, MD; Justine Pudzeis, MD; Evelyne Boesmans, MD; Charlotte Praca, MD; Philippe Brion, MD; Vlad Adrian Alexandrescu, MD, PhD; Vincent Tchana-Sato, MD, PhD
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of...
07/08/2025
Journal of Critical Limb Ischemia
Review
05/15/2025
Khanjan Nagarsheth, MD, MBA, RPVI; Georges Jreij, MD; Fadi Saab, MD, FACC, FSCAI
This review underscores the need for evidence-based pathways tailored to real-world CLTI populations. 
This review underscores the need for evidence-based pathways tailored to real-world CLTI populations. 
This review underscores the need...
05/15/2025
Journal of Critical Limb Ischemia
Review
05/01/2025
Mark Rupasinghe, MD, MBA; Nicholas J. Alianello, DPM; Sreekumar Madassery, MD
This review discusses how to evaluate the underlying causes of chronic wounds and how to characterize a wound during initial workup, and provides an overview of holistic wound care treatment.
This review discusses how to evaluate the underlying causes of chronic wounds and how to characterize a wound during initial workup, and provides an overview of holistic wound care treatment.
This review discusses how to...
05/01/2025
Journal of Critical Limb Ischemia
Original Contribution
04/14/2025
David Heister, MD, PhD; Taylor Pickering, DO; Sameh M. Sayfo, MD, MBA, FABVM
This report describes a case of computed tomography-guided lumbar sympathectomy for palliative treatment of severe rest pain in a patient who was not a candidate for either open or endovascular treatments.
This report describes a case of computed tomography-guided lumbar sympathectomy for palliative treatment of severe rest pain in a patient who was not a candidate for either open or endovascular treatments.
This report describes a case of...
04/14/2025
Journal of Critical Limb Ischemia

Current Issue

Editorial/Commentary
07/23/2025
Marta Lobato, MD; August Ysa, MD, EBVS
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the...
07/23/2025
Journal of Critical Limb Ischemia
Original Contribution
07/08/2025
Arnaud Kerzmann, MD; Justine Pudzeis, MD; Evelyne Boesmans, MD; Charlotte Praca, MD; Philippe Brion, MD; Vlad Adrian Alexandrescu, MD, PhD; Vincent Tchana-Sato, MD, PhD
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of...
07/08/2025
Journal of Critical Limb Ischemia

Videos & Interviews

Dr van den Berg
Videos
12/02/2024
Jos C. van den Berg, MD, PhD; Thomas Zeller, MD, PhD
CLI Global Society European Chapter Chairman Jos van den Berg, MD, and Vice-Chairman Thomas Zeller, MD, discuss the work that the Chapter has been doing to improve the lives of patients with CLTI.
CLI Global Society European Chapter Chairman Jos van den Berg, MD, and Vice-Chairman Thomas Zeller, MD, discuss the work that the Chapter has been doing to improve the lives of patients with CLTI.
CLI Global Society European...
12/02/2024
Journal of Critical Limb Ischemia
Abigail Mize
Videos
11/25/2024
Abigail Mize, BS, RDCS, RVT; David B. Alper, DPM
11/25/2024
Journal of Critical Limb Ischemia
Dr Katzen
Videos
11/18/2024
Barry T. Katzen, MD, FACC, FACR, FSIR
11/18/2024
Journal of Critical Limb Ischemia
Videos
11/13/2024
Fadi Saab, MD, FACC, FSCAI; Zola N'Dandu, MD; Khanjan Nagarsheth, MD, MBA, RPVI; Bret N. Wiechmann, MD, FSIR, FAHA
11/13/2024
Journal of Critical Limb Ischemia
Videos
09/11/2024
Journal of Critical Limb Ischemia
Videos
09/10/2024
Journal of Critical Limb Ischemia
Videos
09/08/2023
Barry T. Katzen, MD, FACC, FACR, FSIR
09/08/2023
Journal of Critical Limb Ischemia

Original Research

Original Contribution
07/08/2025
Arnaud Kerzmann, MD; Justine Pudzeis, MD; Evelyne Boesmans, MD; Charlotte Praca, MD; Philippe Brion, MD; Vlad Adrian Alexandrescu, MD, PhD; Vincent Tchana-Sato, MD, PhD
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of...
07/08/2025
Journal of Critical Limb Ischemia
Original Contribution
04/14/2025
David Heister, MD, PhD; Taylor Pickering, DO; Sameh M. Sayfo, MD, MBA, FABVM
This report describes a case of computed tomography-guided lumbar sympathectomy for palliative treatment of severe rest pain in a patient who was not a candidate for either open or endovascular treatments.
This report describes a case of computed tomography-guided lumbar sympathectomy for palliative treatment of severe rest pain in a patient who was not a candidate for either open or endovascular treatments.
This report describes a case of...
04/14/2025
Journal of Critical Limb Ischemia
Original Contribution
04/02/2025
Ahmad Hallak, MD; Naveed S. Zaman, BS; Ayitevi Agbodji, MD, MPH; Mukosolu Florence Obi, MD; Jonathan Bonilla, MD; Zola N'Dandu, MD
The authors present the case of a 64-year-old man with renal insufficiency and CLTI complicated by a nonhealing ulcer who was successfully revascularized using deep venous arterialization with zero iodinated contrast technique.
The authors present the case of a 64-year-old man with renal insufficiency and CLTI complicated by a nonhealing ulcer who was successfully revascularized using deep venous arterialization with zero iodinated contrast technique.
The authors present the case of...
04/02/2025
Journal of Critical Limb Ischemia
Original Contribution
03/10/2025
Suzanna Fitzpatrick, DNP, ACNP-BC, FNP-BC; Eleanor Dunlap, ACNP-BC; Georg J. Furtmüller, MD; Khanjan Nagarsheth, MD, MBA, RPVI
In this study on caregiver burden, the Zarit Burden Interview (ZBI) and the Short Form Zarit Burden Interview (ZBI-12) were used to assess caregiver burden in 10 patients with lower extremity amputation who presented with a caretaker.
In this study on caregiver burden, the Zarit Burden Interview (ZBI) and the Short Form Zarit Burden Interview (ZBI-12) were used to assess caregiver burden in 10 patients with lower extremity amputation who presented with a caretaker.
In this study on caregiver...
03/10/2025
Journal of Critical Limb Ischemia
Original Contribution
10/08/2024
Thomas Zeller, MD, PhD; Masato Nakamura, MD, PhD; Michael Lichtenberg, MD, FESC
Endovascular treatment of peripheral artery disease is challenging in patients with CLTI and complex lesions, and optimal treatment strategies are not established.
Endovascular treatment of peripheral artery disease is challenging in patients with CLTI and complex lesions, and optimal treatment strategies are not established.
Endovascular treatment of...
10/08/2024
Journal of Critical Limb Ischemia
Original Contribution
09/18/2024
Sara Speziali, MD; Elena Giacomelli, MD; Aaron Thomas Fargion, MD; Rossella Di Domenico, MD; Marianna Peruffo, MD; Gabriele Piffaretti, MD; Raffaele Pulli, MD; Walter Dorigo, MD
In this study, the authors retrospectively compared the outcomes of heparin-bonded expanded polytetrafluoroethylene (HePTFE) and ASV in patients undergoing below-the-knee femoropopliteal bypass for CLI.
In this study, the authors retrospectively compared the outcomes of heparin-bonded expanded polytetrafluoroethylene (HePTFE) and ASV in patients undergoing below-the-knee femoropopliteal bypass for CLI.
In this study, the authors...
09/18/2024
Journal of Critical Limb Ischemia
Original Contribution
05/20/2024
Eleanor Dunlap, ACNP-BC; Joshua Plant, MD; Khanjan Nagarsheth, MD, MBA, RPVI
Phantom limb pain is a common complication after MLEA, occurring in approximately 85% of patients that significantly affects amputees’ mobility, ability to perform tasks of daily living, and overall quality of life.
Phantom limb pain is a common complication after MLEA, occurring in approximately 85% of patients that significantly affects amputees’ mobility, ability to perform tasks of daily living, and overall quality of life.
Phantom limb pain is a common...
05/20/2024
Journal of Critical Limb Ischemia
Original Contribution
05/13/2024
Anthony Pham, BS; Geoff Thomas, BS; Vivie Tran, MS; Dixon Santana, MD; Sahil A. Parikh, MD, FACC, FSCAI; Subhash Banerjee, MD; Craig M. Walker, MD, FACC, FACP, FSCAI, FCCP; Fadi Saab, MD, FACC, FSCAI; Jihad A. Mustapha, MD, FACC, FSCAI; Mohammad M. Ansari, MD
The authors seek to explore the representation of minority groups and women in clinical studies evaluating the usage of drug-coated balloons for treatment in PAD/CLTI.
The authors seek to explore the representation of minority groups and women in clinical studies evaluating the usage of drug-coated balloons for treatment in PAD/CLTI.
The authors seek to explore the...
05/13/2024
Journal of Critical Limb Ischemia
Original Contribution
03/26/2024
Samuel A. Salazar, BS; Rafey Khan, BS; Akash D. Nijhawan, BS; Matthew Kilbridge, MD; Varshana Gurusamy, MD; Yasaswi Vengalasetti, MS; Alex Powell, MD; Brian J. Schiro, MD; Constantino S. Peña, MD, FAHA, FSCCT, FSIR; Ripal T. Gandhi, MD, FSIR, FSVM; Andrew Scott Niekamp, MD
Presence of calcification is a significant risk factor for treatment resistance during endovascular therapy, limiting vessel expansion and increasing rates of complication. This study assesses the safety and efficacy of IVL in the treatment...
Presence of calcification is a significant risk factor for treatment resistance during endovascular therapy, limiting vessel expansion and increasing rates of complication. This study assesses the safety and efficacy of IVL in the treatment...
Presence of calcification is a...
03/26/2024
Journal of Critical Limb Ischemia
Original Contribution
03/21/2024
Kimberly A. Gerling, MD; Joshua A. Gabel, MD; Richard Neville, MD
This analysis takes a look at the pattern and complexity of surgical bypass in the context of participation in a limb preservation program.
This analysis takes a look at the pattern and complexity of surgical bypass in the context of participation in a limb preservation program.
This analysis takes a look at...
03/21/2024
Journal of Critical Limb Ischemia

Editorial/Commentary

Editorial/Commentary
07/23/2025
Marta Lobato, MD; August Ysa, MD, EBVS
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the...
07/23/2025
Journal of Critical Limb Ischemia
Editorial/Commentary
01/29/2025
Aishwarya Raja, MD; Eric A. Secemsky, MD, MSc, RPVI, FACC, FAHA, FSCAI
In the latest issue of JACC: Cardiovascular Interventions, Raja et al analyzed trends in the institutional use of endovascular revascularization and surgical bypass among 196,070 Medicare beneficiaries aged 66 and older with CLI.
In the latest issue of JACC: Cardiovascular Interventions, Raja et al analyzed trends in the institutional use of endovascular revascularization and surgical bypass among 196,070 Medicare beneficiaries aged 66 and older with CLI.
In the latest issue of JACC:...
01/29/2025
Journal of Critical Limb Ischemia
Editorial/Commentary
06/20/2024
Christos Dimopoulos, MD, PhD; Theodosios Bisdas, MD, PhD
Phantom limb pain (PLP) encapsulates the complex spectrum of pain, both physical and psychological. Understanding and treating PLP requires a holistic approach that considers the intricate interplay between the brain, body, and mind.
Phantom limb pain (PLP) encapsulates the complex spectrum of pain, both physical and psychological. Understanding and treating PLP requires a holistic approach that considers the intricate interplay between the brain, body, and mind.
Phantom limb pain (PLP)...
06/20/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
03/18/2024
Theodosios Bisdas, MD, PhD; Konstantinos Stavroulakis, MD
Abdelghany et al, acting on behalf of the Publication Committee of the Critical Limb Ischemia Global Society, presented an insightful analysis detailing the historical progression of CLTI treatment. This historical journey has been marked by...
Abdelghany et al, acting on behalf of the Publication Committee of the Critical Limb Ischemia Global Society, presented an insightful analysis detailing the historical progression of CLTI treatment. This historical journey has been marked by...
Abdelghany et al, acting on...
03/18/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
03/14/2024
Sean W. Dooley, MD; Eric A. Secemsky, MD, MSc, RPVI, FACC, FAHA, FSCAI; Michael R. Jaff, MD, DO
In this commentary, the authors address the current challenges in CLTI care.
In this commentary, the authors address the current challenges in CLTI care.
In this commentary, the authors...
03/14/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
01/10/2024
Fadi Saab, MD, FACC, FSCAI; Khanjan Nagarsheth, MD, MBA, RPVI
Drs. Saab and Nagarsheth provide commentary on the article "The Tack-Optimized Balloon Angioplasty (TOBA) II Below-the-Knee Trial: 36-Month Results" by Adams, et al. 
Drs. Saab and Nagarsheth provide commentary on the article "The Tack-Optimized Balloon Angioplasty (TOBA) II Below-the-Knee Trial: 36-Month Results" by Adams, et al. 
Drs. Saab and Nagarsheth provide...
01/10/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
01/10/2024
Zola N'Dandu, MD
Dr. N'Dandu comments on the article "Outcomes of Reintervention in Percutaneous Deep Venous Arterialization" by Zaman et al.
Dr. N'Dandu comments on the article "Outcomes of Reintervention in Percutaneous Deep Venous Arterialization" by Zaman et al.
Dr. N'Dandu comments on the...
01/10/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
09/29/2023
Grigorios Korosoglou, MD; Erwin Blessing, MD
The authors comment on the article by Papoyan et al, "Retrograde Pedal Access for the Superficial Femoral Artery Recanalization In Critical Limb Ischemia."
The authors comment on the article by Papoyan et al, "Retrograde Pedal Access for the Superficial Femoral Artery Recanalization In Critical Limb Ischemia."
The authors comment on the...
09/29/2023
Journal of Critical Limb Ischemia
Editorial/Commentary
06/11/2023
Constantino S. Peña, MD, FAHA, FSCCT, FSIR
The need for cost-effective, quality care will drive patient treatment decisions and trends. Traditionally, the transfemoral approach has offered a dependable primary access site particularly to approach lower extremity disease. Why should...
The need for cost-effective, quality care will drive patient treatment decisions and trends. Traditionally, the transfemoral approach has offered a dependable primary access site particularly to approach lower extremity disease. Why should...
The need for cost-effective,...
06/11/2023
Journal of Critical Limb Ischemia
Editorial/Commentary
06/09/2023
David Barry, MD; William A. Gray, MD
The development of BRS would have the benefit of mechanical support to prevent early vessel recoil and treat dissection similar to BMS and DES, without the permanent metallic struts that would lead to medium- and long-term complications.
The development of BRS would have the benefit of mechanical support to prevent early vessel recoil and treat dissection similar to BMS and DES, without the permanent metallic struts that would lead to medium- and long-term complications.
The development of BRS would...
06/09/2023
Journal of Critical Limb Ischemia