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Journal of Critical Limb Ischemia

Explore the Journal of Critical Limb Ischemia (JCLI), a quarterly international peer-reviewed journal and online clinical resource for those treating chronic limb-threatening ischemia. JCLI is the official journal of the CLI Global Society.

Recently Published

News
09/08/2025
The FDA has granted 510(k) clearance for the LIBERTY® System, the first FDA cleared single-use, remotely operated robotic system for peripheral endovascular procedures.
The FDA has granted 510(k) clearance for the LIBERTY® System, the first FDA cleared single-use, remotely operated robotic system for peripheral endovascular procedures.
The FDA has granted 510(k)...
09/08/2025
Journal of Critical Limb Ischemia
Dr van den Berg
AMP 2025
08/14/2025
Jos C. van den Berg, MD, PhD
At AMP 2025, Interventional radiologist Jos van den Berg, MD, PhD, from the Clinica Luganese Moncucco in Lugano, Switzerland, delivered a presentation titled “The Economic Burden of CLTI in Europe.”
At AMP 2025, Interventional radiologist Jos van den Berg, MD, PhD, from the Clinica Luganese Moncucco in Lugano, Switzerland, delivered a presentation titled “The Economic Burden of CLTI in Europe.”
At AMP 2025, Interventional...
08/14/2025
Journal of Critical Limb Ischemia
DR NEVILLE
AMP 2025
08/14/2025
Richard Neville, MD
Richard Neville, MD, outlines how CLTI programs are redefining “quality.” The era of anecdotal morbidity and mortality reviews has given way to continuous, data-driven evaluation aligned with value-based care.
Richard Neville, MD, outlines how CLTI programs are redefining “quality.” The era of anecdotal morbidity and mortality reviews has given way to continuous, data-driven evaluation aligned with value-based care.
Richard Neville, MD, outlines...
08/14/2025
Journal of Critical Limb Ischemia
AMBITION BTK TRIAL FOR CLTI
07/24/2025
AMBITION BTK is a prospective, multicenter, randomized controlled trial (RCT) designed to investigate the clinical safety and effectiveness of the Auryon Atherectomy System combined with standard balloon angioplasty, compared to balloon...
AMBITION BTK is a prospective, multicenter, randomized controlled trial (RCT) designed to investigate the clinical safety and effectiveness of the Auryon Atherectomy System combined with standard balloon angioplasty, compared to balloon...
AMBITION BTK is a prospective,...
07/24/2025
Vascular Disease Management
From Vascular Disease Management
Editorial/Commentary
07/23/2025
Marta Lobato, MD; August Ysa, MD, EBVS
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the...
07/23/2025
Journal of Critical Limb Ischemia
Original Contribution
07/08/2025
Arnaud Kerzmann, MD; Justine Pudzeis, MD; Evelyne Boesmans, MD; Charlotte Praca, MD; Philippe Brion, MD; Vlad Adrian Alexandrescu, MD, PhD; Vincent Tchana-Sato, MD, PhD
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of...
07/08/2025
Journal of Critical Limb Ischemia
Review
05/15/2025
Khanjan Nagarsheth, MD, MBA, RPVI; Georges Jreij, MD; Fadi Saab, MD, FACC, FSCAI
This review underscores the need for evidence-based pathways tailored to real-world CLTI populations. 
This review underscores the need for evidence-based pathways tailored to real-world CLTI populations. 
This review underscores the need...
05/15/2025
Journal of Critical Limb Ischemia
Review
05/01/2025
Mark Rupasinghe, MD, MBA; Nicholas J. Alianello, DPM; Sreekumar Madassery, MD
This review discusses how to evaluate the underlying causes of chronic wounds and how to characterize a wound during initial workup, and provides an overview of holistic wound care treatment.
This review discusses how to evaluate the underlying causes of chronic wounds and how to characterize a wound during initial workup, and provides an overview of holistic wound care treatment.
This review discusses how to...
05/01/2025
Journal of Critical Limb Ischemia
Original Contribution
04/14/2025
David Heister, MD, PhD; Taylor Pickering, DO; Sameh M. Sayfo, MD, MBA, FABVM
This report describes a case of computed tomography-guided lumbar sympathectomy for palliative treatment of severe rest pain in a patient who was not a candidate for either open or endovascular treatments.
This report describes a case of computed tomography-guided lumbar sympathectomy for palliative treatment of severe rest pain in a patient who was not a candidate for either open or endovascular treatments.
This report describes a case of...
04/14/2025
Journal of Critical Limb Ischemia
Original Contribution
04/02/2025
Ahmad Hallak, MD; Naveed S. Zaman, BS; Ayitevi Agbodji, MD, MPH; Mukosolu Florence Obi, MD; Jonathan Bonilla, MD; Zola N'Dandu, MD
The authors present the case of a 64-year-old man with renal insufficiency and CLTI complicated by a nonhealing ulcer who was successfully revascularized using deep venous arterialization with zero iodinated contrast technique.
The authors present the case of a 64-year-old man with renal insufficiency and CLTI complicated by a nonhealing ulcer who was successfully revascularized using deep venous arterialization with zero iodinated contrast technique.
The authors present the case of...
04/02/2025
Journal of Critical Limb Ischemia

Current Issue

Editorial/Commentary
07/23/2025
Marta Lobato, MD; August Ysa, MD, EBVS
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the...
07/23/2025
Journal of Critical Limb Ischemia
Original Contribution
07/08/2025
Arnaud Kerzmann, MD; Justine Pudzeis, MD; Evelyne Boesmans, MD; Charlotte Praca, MD; Philippe Brion, MD; Vlad Adrian Alexandrescu, MD, PhD; Vincent Tchana-Sato, MD, PhD
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of vessel preparation where the Rotarex S rotational atherothrombectomy device induced arterial wall ruptures and describe how the ruptures were treated in 2 different ways. 
The authors present 2 cases of...
07/08/2025
Journal of Critical Limb Ischemia

Meeting Coverage

KJ Nagarsheth, MD
Sponsored
09/23/2025
Khanjan Nagarsheth, MD, MBA, RPVI
Join Dr. KJ Nagarsheth as he reflects on his experience with PTAB Therapy using the DETOUR™ system.
Join Dr. KJ Nagarsheth as he reflects on his experience with PTAB Therapy using the DETOUR™ system.
Join Dr. KJ Nagarsheth as he...
09/23/2025
Vascular Disease Management
Sonya Noor, MD
Sponsored
09/23/2025
Sonya Noor, MD
In this video from AMP 2025, vascular surgeon Dr. Sonya Noor discusses the evolving landscape of treating complex PAD.
In this video from AMP 2025, vascular surgeon Dr. Sonya Noor discusses the evolving landscape of treating complex PAD.
In this video from AMP 2025,...
09/23/2025
Vascular Disease Management
Mike Watts, MD
AMP 2025
09/18/2025
Mike Watts, MD, FSIR
Mike Watts, MD, FSIR, discusses his presentation on the use of wearables and artificial intelligence in the prevention and treatment of chronic limb-threatening ischemia.
Mike Watts, MD, FSIR, discusses his presentation on the use of wearables and artificial intelligence in the prevention and treatment of chronic limb-threatening ischemia.
Mike Watts, MD, FSIR, discusses...
09/18/2025
Vascular Disease Management
Dr Madassery
AMP 2025
09/10/2025
Kumar Madassery, MD
Dr Kumar Madassery discusses his AMP 2025 presentation on angiography for patients with chronic limb-threatening ischemia.
Dr Kumar Madassery discusses his AMP 2025 presentation on angiography for patients with chronic limb-threatening ischemia.
Dr Kumar Madassery discusses his...
09/10/2025
Vascular Disease Management
Bret Wiechmann, MD
OBL Corner
09/04/2025
Bret N. Wiechmann, MD, FSIR, FAHA; Mike Watts, MD, FSIR
Drs Bret Wiechmann and Mike Watts discuss the differences between hospitals, ambulatory surgery centers, and office-based labs when dealing with CLTI interventions.
Drs Bret Wiechmann and Mike Watts discuss the differences between hospitals, ambulatory surgery centers, and office-based labs when dealing with CLTI interventions.
Drs Bret Wiechmann and Mike...
09/04/2025
Vascular Disease Management
Teri Yates
AMP 2025
08/15/2025
Teri Yates
Teri Yates, CEO of Accountable Physician Advisors and DocCentric Surgery Centers, delivered an in-depth presentation that provided a detailed comparison between OBLs and ASCs. She highlighted regulatory distinctions, facility requirements,...
Teri Yates, CEO of Accountable Physician Advisors and DocCentric Surgery Centers, delivered an in-depth presentation that provided a detailed comparison between OBLs and ASCs. She highlighted regulatory distinctions, facility requirements,...
Teri Yates, CEO of Accountable...
08/15/2025
Vascular Disease Management
Earl Johnson MD
AMP 2025
08/15/2025
Earl M. Johnson, Jr., MD, FACS
Earl M. Johnson, Jr., MD, FACS, presented a discussion on the transformative role plastic surgery can play when incorporated early in a patient’s treatment plan. He emphasized that proactive, coordinated intervention significantly enhances...
Earl M. Johnson, Jr., MD, FACS, presented a discussion on the transformative role plastic surgery can play when incorporated early in a patient’s treatment plan. He emphasized that proactive, coordinated intervention significantly enhances...
Earl M. Johnson, Jr., MD, FACS,...
08/15/2025
Vascular Disease Management
Caroline Fife, MD
AMP 2025
08/15/2025
Caroline E. Fife, MD, FAAFP, CWS, FUHM
Caroline E. Fife, MD, underscored how gaps in diagnosis coding, classification disagreements, and underreporting distort both prevalence and cost estimates, leading to inadequate attention and funding.
Caroline E. Fife, MD, underscored how gaps in diagnosis coding, classification disagreements, and underreporting distort both prevalence and cost estimates, leading to inadequate attention and funding.
Caroline E. Fife, MD,...
08/15/2025
Vascular Disease Management
Abigail Mize
AMP 2025
08/15/2025
Abigail Mize, BS, RDCS, RVT
Abigail Mize, BS, RDCS, RVT, gave a presentation entitled "Utilization of Ultrasound to Identify and Treat Complications." She emphasized that while prevention remains the best strategy, complications can arise even with the most skilled...
Abigail Mize, BS, RDCS, RVT, gave a presentation entitled "Utilization of Ultrasound to Identify and Treat Complications." She emphasized that while prevention remains the best strategy, complications can arise even with the most skilled...
Abigail Mize, BS, RDCS, RVT,...
08/15/2025
Vascular Disease Management

Videos

Drs Zeller and van den Berg
Videos
12/02/2024
Jos C. van den Berg, MD, PhD; Thomas Zeller, MD, PhD
CLI Global Society European Chapter Chairman Jos van den Berg, MD, and Vice-Chairman Thomas Zeller, MD, discuss the work that the Chapter has been doing to improve the lives of patients with CLTI.
CLI Global Society European Chapter Chairman Jos van den Berg, MD, and Vice-Chairman Thomas Zeller, MD, discuss the work that the Chapter has been doing to improve the lives of patients with CLTI.
CLI Global Society European...
12/02/2024
Journal of Critical Limb Ischemia
Videos
11/25/2024
Abigail Mize, BS, RDCS, RVT; David B. Alper, DPM
11/25/2024
Journal of Critical Limb Ischemia
Videos
11/18/2024
Barry T. Katzen, MD, FACC, FACR, FSIR
11/18/2024
Journal of Critical Limb Ischemia
Videos
11/13/2024
Fadi Saab, MD, FACC, FSCAI; Zola N'Dandu, MD; Khanjan Nagarsheth, MD, MBA, RPVI; Bret N. Wiechmann, MD, FSIR, FAHA
11/13/2024
Journal of Critical Limb Ischemia
Videos
09/11/2024
Journal of Critical Limb Ischemia
Videos
09/10/2024
Journal of Critical Limb Ischemia
Videos
09/08/2023
Barry T. Katzen, MD, FACC, FACR, FSIR
09/08/2023
Journal of Critical Limb Ischemia
Videos
05/09/2023
Journal of Critical Limb Ischemia

Editorial/Commentary

Editorial/Commentary
07/23/2025
Marta Lobato, MD; August Ysa, MD, EBVS
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the article "A Systematic Review of Clinical Trials in Patients With Critical Limb-Threatening Ischemia” by Nagarsheth et al.
Drs Lobato and Ysa review the...
07/23/2025
Journal of Critical Limb Ischemia
Editorial/Commentary
01/29/2025
Aishwarya Raja, MD; Eric A. Secemsky, MD, MSc, RPVI, FACC, FAHA, FSCAI
In the latest issue of JACC: Cardiovascular Interventions, Raja et al analyzed trends in the institutional use of endovascular revascularization and surgical bypass among 196,070 Medicare beneficiaries aged 66 and older with CLI.
In the latest issue of JACC: Cardiovascular Interventions, Raja et al analyzed trends in the institutional use of endovascular revascularization and surgical bypass among 196,070 Medicare beneficiaries aged 66 and older with CLI.
In the latest issue of JACC:...
01/29/2025
Journal of Critical Limb Ischemia
Editorial/Commentary
06/20/2024
Christos Dimopoulos, MD, PhD; Theodosios Bisdas, MD, PhD
Phantom limb pain (PLP) encapsulates the complex spectrum of pain, both physical and psychological. Understanding and treating PLP requires a holistic approach that considers the intricate interplay between the brain, body, and mind.
Phantom limb pain (PLP) encapsulates the complex spectrum of pain, both physical and psychological. Understanding and treating PLP requires a holistic approach that considers the intricate interplay between the brain, body, and mind.
Phantom limb pain (PLP)...
06/20/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
03/18/2024
Theodosios Bisdas, MD, PhD; Konstantinos Stavroulakis, MD
Abdelghany et al, acting on behalf of the Publication Committee of the Critical Limb Ischemia Global Society, presented an insightful analysis detailing the historical progression of CLTI treatment. This historical journey has been marked by...
Abdelghany et al, acting on behalf of the Publication Committee of the Critical Limb Ischemia Global Society, presented an insightful analysis detailing the historical progression of CLTI treatment. This historical journey has been marked by...
Abdelghany et al, acting on...
03/18/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
03/14/2024
Sean W. Dooley, MD; Eric A. Secemsky, MD, MSc, RPVI, FACC, FAHA, FSCAI; Michael R. Jaff, MD, DO
In this commentary, the authors address the current challenges in CLTI care.
In this commentary, the authors address the current challenges in CLTI care.
In this commentary, the authors...
03/14/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
01/10/2024
Fadi Saab, MD, FACC, FSCAI; Khanjan Nagarsheth, MD, MBA, RPVI
Drs. Saab and Nagarsheth provide commentary on the article "The Tack-Optimized Balloon Angioplasty (TOBA) II Below-the-Knee Trial: 36-Month Results" by Adams, et al. 
Drs. Saab and Nagarsheth provide commentary on the article "The Tack-Optimized Balloon Angioplasty (TOBA) II Below-the-Knee Trial: 36-Month Results" by Adams, et al. 
Drs. Saab and Nagarsheth provide...
01/10/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
01/10/2024
Zola N'Dandu, MD
Dr. N'Dandu comments on the article "Outcomes of Reintervention in Percutaneous Deep Venous Arterialization" by Zaman et al.
Dr. N'Dandu comments on the article "Outcomes of Reintervention in Percutaneous Deep Venous Arterialization" by Zaman et al.
Dr. N'Dandu comments on the...
01/10/2024
Journal of Critical Limb Ischemia
Editorial/Commentary
09/29/2023
Grigorios Korosoglou, MD; Erwin Blessing, MD
The authors comment on the article by Papoyan et al, "Retrograde Pedal Access for the Superficial Femoral Artery Recanalization In Critical Limb Ischemia."
The authors comment on the article by Papoyan et al, "Retrograde Pedal Access for the Superficial Femoral Artery Recanalization In Critical Limb Ischemia."
The authors comment on the...
09/29/2023
Journal of Critical Limb Ischemia
Editorial/Commentary
06/11/2023
Constantino S. Peña, MD, FAHA, FSCCT, FSIR
The need for cost-effective, quality care will drive patient treatment decisions and trends. Traditionally, the transfemoral approach has offered a dependable primary access site particularly to approach lower extremity disease. Why should...
The need for cost-effective, quality care will drive patient treatment decisions and trends. Traditionally, the transfemoral approach has offered a dependable primary access site particularly to approach lower extremity disease. Why should...
The need for cost-effective,...
06/11/2023
Journal of Critical Limb Ischemia
Editorial/Commentary
06/09/2023
David Barry, MD; William A. Gray, MD
The development of BRS would have the benefit of mechanical support to prevent early vessel recoil and treat dissection similar to BMS and DES, without the permanent metallic struts that would lead to medium- and long-term complications.
The development of BRS would have the benefit of mechanical support to prevent early vessel recoil and treat dissection similar to BMS and DES, without the permanent metallic struts that would lead to medium- and long-term complications.
The development of BRS would...
06/09/2023
Journal of Critical Limb Ischemia