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Sarcoma Specialty Channel

Mrinal Gounder, MD; Rashmi Chugh, MD; Ravin Ratan, MD, MEd
Videos
11/03/2025
Mrinal Gounder, MD; Rashmi Chugh, MD; Ravin Ratan, MD, MEd
In this video, a panel of experts look ahead to the evolving treatment paradigm for desmoid tumors, underscoring the clinical significance of the RINGSIDE trial of the gamma secretase inhibitor AL102/varegacestat and the growing interest in...
In this video, a panel of experts look ahead to the evolving treatment paradigm for desmoid tumors, underscoring the clinical significance of the RINGSIDE trial of the gamma secretase inhibitor AL102/varegacestat and the growing interest in...
In this video, a panel of...
11/03/2025
Oncology
Mrinal Gounder, MD; Rashmi Chugh, MD; Ravin Ratan, MD, MEd
Videos
11/03/2025
Mrinal Gounder, MD; Rashmi Chugh, MD; Ravin Ratan, MD, MEd
Expert clinicians review the latest data on systemic therapies for desmoid tumors, highlighting emerging clinical evidence and discussing how these findings are shaping treatment selection and real-world practice.
Expert clinicians review the latest data on systemic therapies for desmoid tumors, highlighting emerging clinical evidence and discussing how these findings are shaping treatment selection and real-world practice.
Expert clinicians review the...
11/03/2025
Oncology
Mrinal Gounder, MD; Rashmi Chugh, MD; Ravin Ratan, MD, MEd
Videos
11/03/2025
Mrinal Gounder, MD; Rashmi Chugh, MD; Ravin Ratan, MD, MEd
In this video, the panel discusses the clinical circumstances that prompt treatment initiation in patients with desmoid tumors, outlining key factors that guide decision-making and timing of intervention.
In this video, the panel discusses the clinical circumstances that prompt treatment initiation in patients with desmoid tumors, outlining key factors that guide decision-making and timing of intervention.
In this video, the panel...
11/03/2025
Oncology
Mrinal Gounder, MD; Rashmi Chugh, MD; Ravin Ratan, MD, MEd
Videos
11/03/2025
Mrinal Gounder, MD; Rashmi Chugh, MD; Ravin Ratan, MD, MEd
A panel of expert clinicians define desmoid tumors and examine the patient journey following diagnosis, with a focus on diagnostic challenges, risk assessment, and key considerations that inform early management strategies.
A panel of expert clinicians define desmoid tumors and examine the patient journey following diagnosis, with a focus on diagnostic challenges, risk assessment, and key considerations that inform early management strategies.
A panel of expert clinicians...
11/03/2025
Oncology
FDA Approval
09/13/2024
Stephanie Holland
On September 12th, 2024, the US FDA approved subcutaneous coformulation of atezolizumab plus hyaluronidase for adult patients with non-small cell lung cancer, small cell lung cancer, hepatocellular carcinoma, melanoma, and alveolar soft part...
On September 12th, 2024, the US FDA approved subcutaneous coformulation of atezolizumab plus hyaluronidase for adult patients with non-small cell lung cancer, small cell lung cancer, hepatocellular carcinoma, melanoma, and alveolar soft part...
On September 12th, 2024, the US...
09/13/2024
Oncology
FDA Approval
08/02/2024
Allison Casey
On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...
On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...
On August 2, 2024, the US Food...
08/02/2024
Oncology
News
06/02/2022
John Otrompke, BA, JD
Second-line or later treatment with selinexor for metastatic, advanced dedifferentiated liposarcoma was associated with longer PFS and time to next treatment compared to placebo.
Second-line or later treatment with selinexor for metastatic, advanced dedifferentiated liposarcoma was associated with longer PFS and time to next treatment compared to placebo.
Second-line or later treatment...
06/02/2022
Oncology
Test Your Knowledge
09/14/2021
True or false: In the treatment of advanced STS, randomized trials with QoL assessment were more likely to achieve the ESMO-Magnitude of Clinical Benefit Scale substantial benefit threshold.
True or false: In the treatment of advanced STS, randomized trials with QoL assessment were more likely to achieve the ESMO-Magnitude of Clinical Benefit Scale substantial benefit threshold.
True or false: In the treatment...
09/14/2021
Oncology
Conference Coverage
09/14/2021
The ESMO-MCBS medical device was evaluated for its ability to assess the magnitude of clinical benefit, quality of life, and outcomes in advanced STS and GIST in; these data were presented at the virtual 2021 ESMO Congress.
The ESMO-MCBS medical device was evaluated for its ability to assess the magnitude of clinical benefit, quality of life, and outcomes in advanced STS and GIST in; these data were presented at the virtual 2021 ESMO Congress.
The ESMO-MCBS medical device was...
09/14/2021
Oncology
Test Your Knowledge
11/09/2020
True or false: The FDA recently approved the first new AIDS-related Kaposi sarcoma treatment in 6 years.
True or false: The FDA recently approved the first new AIDS-related Kaposi sarcoma treatment in 6 years.
True or false: The FDA recently...
11/09/2020
Oncology
News
10/26/2020
The FDA has approved the NGS companion diagnostic FoundationOne CDx test to identify NTRK gene fusions in solid tumor tissue from patients eligible for treatment with larotrectinib.
The FDA has approved the NGS companion diagnostic FoundationOne CDx test to identify NTRK gene fusions in solid tumor tissue from patients eligible for treatment with larotrectinib.
The FDA has approved the NGS...
10/26/2020
Oncology

News

FDA Approval
09/13/2024
Stephanie Holland
On September 12th, 2024, the US FDA approved subcutaneous coformulation of atezolizumab plus hyaluronidase for adult patients with non-small cell lung cancer, small cell lung cancer, hepatocellular carcinoma, melanoma, and alveolar soft part...
On September 12th, 2024, the US FDA approved subcutaneous coformulation of atezolizumab plus hyaluronidase for adult patients with non-small cell lung cancer, small cell lung cancer, hepatocellular carcinoma, melanoma, and alveolar soft part...
On September 12th, 2024, the US...
09/13/2024
Oncology
FDA Approval
08/02/2024
Allison Casey
On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...
On August 2, 2024, the US Food and Drug Administration (FDA) granted accelerated approval to afamitresgene autoleucel for the treatment of adult patients with certain unresectable or metastatic synovial sarcomas who had received prior...
On August 2, 2024, the US Food...
08/02/2024
Oncology
News
06/02/2022
John Otrompke, BA, JD
Second-line or later treatment with selinexor for metastatic, advanced dedifferentiated liposarcoma was associated with longer PFS and time to next treatment compared to placebo.
Second-line or later treatment with selinexor for metastatic, advanced dedifferentiated liposarcoma was associated with longer PFS and time to next treatment compared to placebo.
Second-line or later treatment...
06/02/2022
Oncology
Conference Coverage
09/14/2021
The ESMO-MCBS medical device was evaluated for its ability to assess the magnitude of clinical benefit, quality of life, and outcomes in advanced STS and GIST in; these data were presented at the virtual 2021 ESMO Congress.
The ESMO-MCBS medical device was evaluated for its ability to assess the magnitude of clinical benefit, quality of life, and outcomes in advanced STS and GIST in; these data were presented at the virtual 2021 ESMO Congress.
The ESMO-MCBS medical device was...
09/14/2021
Oncology
News
10/26/2020
The FDA has approved the NGS companion diagnostic FoundationOne CDx test to identify NTRK gene fusions in solid tumor tissue from patients eligible for treatment with larotrectinib.
The FDA has approved the NGS companion diagnostic FoundationOne CDx test to identify NTRK gene fusions in solid tumor tissue from patients eligible for treatment with larotrectinib.
The FDA has approved the NGS...
10/26/2020
Oncology
News
09/23/2020
Doxorubicin combined with pembrolizumab has shown promise in the treatment of patients with advanced anthracycline-naïve sarcoma, according to phase 1/2 study findings.
Doxorubicin combined with pembrolizumab has shown promise in the treatment of patients with advanced anthracycline-naïve sarcoma, according to phase 1/2 study findings.
Doxorubicin combined with...
09/23/2020
Oncology
News
05/31/2020
A maintenance therapy regimen comprising oral cyclophosphamide plus celecoxib has demonstrated feasibility in patients with metastatic Ewing sarcoma.
A maintenance therapy regimen comprising oral cyclophosphamide plus celecoxib has demonstrated feasibility in patients with metastatic Ewing sarcoma.
A maintenance therapy regimen...
05/31/2020
Oncology
News
05/15/2020
The FDA has approved pomalidomide for use in adults with AIDS-related Kaposi sarcoma unresponsive to antiretroviral therapy and Kaposi sarcoma in HIV-negative adults.
The FDA has approved pomalidomide for use in adults with AIDS-related Kaposi sarcoma unresponsive to antiretroviral therapy and Kaposi sarcoma in HIV-negative adults.
The FDA has approved...
05/15/2020
Oncology
News
05/06/2020
Germline genetic testing may be warranted for patients with osteosarcoma, according to findings from a study by Lisa Mirabello, PhD, et al.
Germline genetic testing may be warranted for patients with osteosarcoma, according to findings from a study by Lisa Mirabello, PhD, et al.
Germline genetic testing may be...
05/06/2020
Oncology
News
04/29/2020
Adding olaratumab to doxorubicin in patients with advanced STS did not significantly improve OS in the ANNOUNCE clinical trial.
Adding olaratumab to doxorubicin in patients with advanced STS did not significantly improve OS in the ANNOUNCE clinical trial.
Adding olaratumab to doxorubicin...
04/29/2020
Oncology

Interactive Features

Test Your Knowledge
09/14/2021
True or false: In the treatment of advanced STS, randomized trials with QoL assessment were more likely to achieve the ESMO-Magnitude of Clinical Benefit Scale substantial benefit threshold.
True or false: In the treatment of advanced STS, randomized trials with QoL assessment were more likely to achieve the ESMO-Magnitude of Clinical Benefit Scale substantial benefit threshold.
True or false: In the treatment...
09/14/2021
Oncology
Test Your Knowledge
11/09/2020
True or false: The FDA recently approved the first new AIDS-related Kaposi sarcoma treatment in 6 years.
True or false: The FDA recently approved the first new AIDS-related Kaposi sarcoma treatment in 6 years.
True or false: The FDA recently...
11/09/2020
Oncology
Test Your Knowledge
08/13/2020
In a large clinical study, which of the following agents yielded durable responses in patients with epithelioid sarcoma?
In a large clinical study, which of the following agents yielded durable responses in patients with epithelioid sarcoma?
In a large clinical study, which...
08/13/2020
Oncology
Test Your Knowledge
07/20/2020
True or False: Cabozantinib has shown anti-tumor activity in patients with advanced Ewing sarcoma and osteosarcoma.
True or False: Cabozantinib has shown anti-tumor activity in patients with advanced Ewing sarcoma and osteosarcoma.
True or False: Cabozantinib has...
07/20/2020
Oncology
Test Your Knowledge
10/01/2019
True or False: Pazopanib may be a suitable therapy option for patients with progressive and advanced extraskeletal myxoid chondrosarcoma who do not respond to first-line anthracycline-based chemo.
True or False: Pazopanib may be a suitable therapy option for patients with progressive and advanced extraskeletal myxoid chondrosarcoma who do not respond to first-line anthracycline-based chemo.
True or False: Pazopanib may be...
10/01/2019
Oncology
Test Your Knowledge
07/22/2019
True or false: Among patients with predominantly nonspine bone lesions, single-fraction radiotherapy led to a higher rate of complete or partial pain responses than standard multi-fraction radiotherapy.
True or false: Among patients with predominantly nonspine bone lesions, single-fraction radiotherapy led to a higher rate of complete or partial pain responses than standard multi-fraction radiotherapy.
True or false: Among patients...
07/22/2019
Oncology