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Acute Lymphoblastic Leukemia Specialty Channel

Acute Lymphoblastic Leukemia
Specialty Channel
Matthew Connor, MD
Conference Coverage
01/22/2026
Matthew Connor, MD
Matthew Connor, MD, highlighted emerging ASH 2025 data showing earlier use of CAR T-cell therapy and novel antigen targets for acute lymphoblastic leukemia, along with ponatinib-based frontline strategies.
Matthew Connor, MD, highlighted emerging ASH 2025 data showing earlier use of CAR T-cell therapy and novel antigen targets for acute lymphoblastic leukemia, along with ponatinib-based frontline strategies.
Matthew Connor, MD, highlighted...
01/22/2026
Oncology
Matthew Connor, MD
Conference Coverage
01/16/2026
Matthew Connor, MD
Matthew Connor, MD, reported that IL18-armored CD19 CAR T-cells produced deep, durable remissions with manageable toxicity among heavily pretreated adults with relapsed/refractory B-cell acute lymphoblastic leukemia in a phase 1 trial.
Matthew Connor, MD, reported that IL18-armored CD19 CAR T-cells produced deep, durable remissions with manageable toxicity among heavily pretreated adults with relapsed/refractory B-cell acute lymphoblastic leukemia in a phase 1 trial.
Matthew Connor, MD, reported...
01/16/2026
Oncology
Alexandra Gomez Arteaga, MD
Videos
10/14/2025
Alexandra Gomez Arteaga, MD
Alexandra Gomez Arteaga, MD, shares insights into which patients with acute lymphoblastic leukemia should be considered for transplant, including those failing to meet MRD negativity or who have a higher genomic risk.
Alexandra Gomez Arteaga, MD, shares insights into which patients with acute lymphoblastic leukemia should be considered for transplant, including those failing to meet MRD negativity or who have a higher genomic risk.
Alexandra Gomez Arteaga, MD,...
10/14/2025
Oncology
Elias Jabbour, MD
Conference Coverage
06/29/2025
Elias Jabbour, MD
At the 2025 Great Debates in Hematologic Malignancies meeting, Elias Jabbour, MD, participated in a debate on the optimal regimen for treating Ph-positive ALL, highlighting the benefits of utilizing immunotherapies.
At the 2025 Great Debates in Hematologic Malignancies meeting, Elias Jabbour, MD, participated in a debate on the optimal regimen for treating Ph-positive ALL, highlighting the benefits of utilizing immunotherapies.
At the 2025 Great Debates in...
06/29/2025
Oncology
Shira Dinner, MD
Conference Coverage
06/28/2025
Shira Dinner, MD
Shira Dinner, MD, debates the benefits of chemotherapy followed by allogeneic stem cell transplantation among patients with Philadelphia chromosome-positive acute lymphoblastic leukemia at the 2025 Great Debates in Hematologic Malignancies.
Shira Dinner, MD, debates the benefits of chemotherapy followed by allogeneic stem cell transplantation among patients with Philadelphia chromosome-positive acute lymphoblastic leukemia at the 2025 Great Debates in Hematologic Malignancies.
Shira Dinner, MD, debates the...
06/28/2025
Oncology
Quiz
05/27/2025
In a retrospective study assessing autologous hematopoietic stem cell transplantation for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, which patient subgroup demonstrated superior leukemia-free survival at 5...
In a retrospective study assessing autologous hematopoietic stem cell transplantation for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, which patient subgroup demonstrated superior leukemia-free survival at 5...
In a retrospective study...
05/27/2025
Oncology
News
05/16/2025
Emily Estrada
Autologous hematopoietic stem cell transplantation demonstrated relative safety for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, according to a recent study.
Autologous hematopoietic stem cell transplantation demonstrated relative safety for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, according to a recent study.
Autologous hematopoietic stem...
05/16/2025
Oncology
Quiz
05/05/2025
What was the overall response rate observed at month 3 following treatment with inaticabtagene autoleucel in a phase 2 trial among patients with R/R B-cell acute lymphoblastic leukemia?
What was the overall response rate observed at month 3 following treatment with inaticabtagene autoleucel in a phase 2 trial among patients with R/R B-cell acute lymphoblastic leukemia?
What was the overall response...
05/05/2025
Oncology
News
04/29/2025
Emily Estrada
For patients with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia, dasatinib plus sequential CD19-CD22 CAR T-cell therapy demonstrated improved outcomes and high rates of complete molecular remission.
For patients with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia, dasatinib plus sequential CD19-CD22 CAR T-cell therapy demonstrated improved outcomes and high rates of complete molecular remission.
For patients with newly...
04/29/2025
Oncology
Quiz
04/21/2025
Regarding the durability of remission achieved with inaticabtagene autoleucel therapy among patients with R/R B-ALL in a phase 2 trial, what was the median duration of remission reported?
Regarding the durability of remission achieved with inaticabtagene autoleucel therapy among patients with R/R B-ALL in a phase 2 trial, what was the median duration of remission reported?
Regarding the durability of...
04/21/2025
Oncology
News
03/25/2025
Emily Estrada
Inaticabtagene autoleucel treatment for patients with relapsed/refractory B-cell acute lymphoblastic leukemia showed efficacy and durability in a phase 2 clinical trial.
Inaticabtagene autoleucel treatment for patients with relapsed/refractory B-cell acute lymphoblastic leukemia showed efficacy and durability in a phase 2 clinical trial.
Inaticabtagene autoleucel...
03/25/2025
Oncology

News

Matthew Connor, MD
Conference Coverage
01/22/2026
Matthew Connor, MD
Matthew Connor, MD, highlighted emerging ASH 2025 data showing earlier use of CAR T-cell therapy and novel antigen targets for acute lymphoblastic leukemia, along with ponatinib-based frontline strategies.
Matthew Connor, MD, highlighted emerging ASH 2025 data showing earlier use of CAR T-cell therapy and novel antigen targets for acute lymphoblastic leukemia, along with ponatinib-based frontline strategies.
Matthew Connor, MD, highlighted...
01/22/2026
Oncology
Matthew Connor, MD
Conference Coverage
01/16/2026
Matthew Connor, MD
Matthew Connor, MD, reported that IL18-armored CD19 CAR T-cells produced deep, durable remissions with manageable toxicity among heavily pretreated adults with relapsed/refractory B-cell acute lymphoblastic leukemia in a phase 1 trial.
Matthew Connor, MD, reported that IL18-armored CD19 CAR T-cells produced deep, durable remissions with manageable toxicity among heavily pretreated adults with relapsed/refractory B-cell acute lymphoblastic leukemia in a phase 1 trial.
Matthew Connor, MD, reported...
01/16/2026
Oncology
Alexandra Gomez Arteaga, MD
Videos
10/14/2025
Alexandra Gomez Arteaga, MD
Alexandra Gomez Arteaga, MD, shares insights into which patients with acute lymphoblastic leukemia should be considered for transplant, including those failing to meet MRD negativity or who have a higher genomic risk.
Alexandra Gomez Arteaga, MD, shares insights into which patients with acute lymphoblastic leukemia should be considered for transplant, including those failing to meet MRD negativity or who have a higher genomic risk.
Alexandra Gomez Arteaga, MD,...
10/14/2025
Oncology
Elias Jabbour, MD
Conference Coverage
06/29/2025
Elias Jabbour, MD
At the 2025 Great Debates in Hematologic Malignancies meeting, Elias Jabbour, MD, participated in a debate on the optimal regimen for treating Ph-positive ALL, highlighting the benefits of utilizing immunotherapies.
At the 2025 Great Debates in Hematologic Malignancies meeting, Elias Jabbour, MD, participated in a debate on the optimal regimen for treating Ph-positive ALL, highlighting the benefits of utilizing immunotherapies.
At the 2025 Great Debates in...
06/29/2025
Oncology
Shira Dinner, MD
Conference Coverage
06/28/2025
Shira Dinner, MD
Shira Dinner, MD, debates the benefits of chemotherapy followed by allogeneic stem cell transplantation among patients with Philadelphia chromosome-positive acute lymphoblastic leukemia at the 2025 Great Debates in Hematologic Malignancies.
Shira Dinner, MD, debates the benefits of chemotherapy followed by allogeneic stem cell transplantation among patients with Philadelphia chromosome-positive acute lymphoblastic leukemia at the 2025 Great Debates in Hematologic Malignancies.
Shira Dinner, MD, debates the...
06/28/2025
Oncology
News
05/16/2025
Emily Estrada
Autologous hematopoietic stem cell transplantation demonstrated relative safety for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, according to a recent study.
Autologous hematopoietic stem cell transplantation demonstrated relative safety for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, according to a recent study.
Autologous hematopoietic stem...
05/16/2025
Oncology
News
04/29/2025
Emily Estrada
For patients with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia, dasatinib plus sequential CD19-CD22 CAR T-cell therapy demonstrated improved outcomes and high rates of complete molecular remission.
For patients with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia, dasatinib plus sequential CD19-CD22 CAR T-cell therapy demonstrated improved outcomes and high rates of complete molecular remission.
For patients with newly...
04/29/2025
Oncology
News
03/25/2025
Emily Estrada
Inaticabtagene autoleucel treatment for patients with relapsed/refractory B-cell acute lymphoblastic leukemia showed efficacy and durability in a phase 2 clinical trial.
Inaticabtagene autoleucel treatment for patients with relapsed/refractory B-cell acute lymphoblastic leukemia showed efficacy and durability in a phase 2 clinical trial.
Inaticabtagene autoleucel...
03/25/2025
Oncology
News
02/07/2025
Emily Estrada
For patients with relapsed/refractory B-cell acute lymphoblastic leukemia, obecabtagene autoleucel anti-CD19 CAR-T therapy showed promising durability and tolerability, according to a recent study.
For patients with relapsed/refractory B-cell acute lymphoblastic leukemia, obecabtagene autoleucel anti-CD19 CAR-T therapy showed promising durability and tolerability, according to a recent study.
For patients with...
02/07/2025
Oncology
News
11/25/2024
Stephanie Holland
The FDA has approved an advanced liquid formulation of imatinib for patients with certain leukemias and gastrointestinal tumors to increase dosing accuracy.
The FDA has approved an advanced liquid formulation of imatinib for patients with certain leukemias and gastrointestinal tumors to increase dosing accuracy.
The FDA has approved an advanced...
11/25/2024
Oncology

Interactive Features

Quiz
05/27/2025
In a retrospective study assessing autologous hematopoietic stem cell transplantation for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, which patient subgroup demonstrated superior leukemia-free survival at 5...
In a retrospective study assessing autologous hematopoietic stem cell transplantation for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, which patient subgroup demonstrated superior leukemia-free survival at 5...
In a retrospective study...
05/27/2025
Oncology
Quiz
05/05/2025
What was the overall response rate observed at month 3 following treatment with inaticabtagene autoleucel in a phase 2 trial among patients with R/R B-cell acute lymphoblastic leukemia?
What was the overall response rate observed at month 3 following treatment with inaticabtagene autoleucel in a phase 2 trial among patients with R/R B-cell acute lymphoblastic leukemia?
What was the overall response...
05/05/2025
Oncology
Quiz
04/21/2025
Regarding the durability of remission achieved with inaticabtagene autoleucel therapy among patients with R/R B-ALL in a phase 2 trial, what was the median duration of remission reported?
Regarding the durability of remission achieved with inaticabtagene autoleucel therapy among patients with R/R B-ALL in a phase 2 trial, what was the median duration of remission reported?
Regarding the durability of...
04/21/2025
Oncology
Quiz
08/01/2023
True or False: A treatment regimen of low-intensity mini-hyper CVD plus inotuzumab and blinatumomab demonstrated improved survival outcomes among patients with R/R Philadelphia chromosome-negative CD22-positive pre-B ALL.
True or False: A treatment regimen of low-intensity mini-hyper CVD plus inotuzumab and blinatumomab demonstrated improved survival outcomes among patients with R/R Philadelphia chromosome-negative CD22-positive pre-B ALL.
True or False: A treatment...
08/01/2023
Oncology
Quiz
03/01/2023
True or False: 3 cycles of inotuzumab ozogamicin induction therapy showed promising remission rates in patients aged >55 years with de novo acute B-lymphoblastic leukemia, according to findings from a recent trial.
True or False: 3 cycles of inotuzumab ozogamicin induction therapy showed promising remission rates in patients aged >55 years with de novo acute B-lymphoblastic leukemia, according to findings from a recent trial.
True or False: 3 cycles of...
03/01/2023
Oncology
Quiz
03/01/2023
True or False: The use of blinatumomab during consolidation for high-risk Philadelphia chromosome negative B-Cell precursor acute lymphoblastic leukemia was associated with reduced relapse rates, according to findings from a recent trial.
True or False: The use of blinatumomab during consolidation for high-risk Philadelphia chromosome negative B-Cell precursor acute lymphoblastic leukemia was associated with reduced relapse rates, according to findings from a recent trial.
True or False: The use of...
03/01/2023
Oncology
Quiz
10/05/2022
True or False: Allogeneic hematopoietic stem cell transplantations from matched sibling donors and matched unrelated donors yielded similar long-term outcomes for patients with BCR-ABL-negative ALL.
True or False: Allogeneic hematopoietic stem cell transplantations from matched sibling donors and matched unrelated donors yielded similar long-term outcomes for patients with BCR-ABL-negative ALL.
True or False: Allogeneic...
10/05/2022
Oncology
Quiz
08/23/2022
True or false: The complete remission rate was higher among patients with relapsed/refractory B-cell ALL with lower (rather than with higher) tumor burden receiving treatment with anti-CD19 CAR T-cell therapy.
True or false: The complete remission rate was higher among patients with relapsed/refractory B-cell ALL with lower (rather than with higher) tumor burden receiving treatment with anti-CD19 CAR T-cell therapy.
True or false: The complete...
08/23/2022
Oncology
Quiz
08/05/2022
True or False: Findings from the phase 3 INO-VATE trial revealed that patients with relapsed/refractory ALL who received inotuzumab ozogamicin were less likely to receive subsequent salvage therapy than those who received standard...
True or False: Findings from the phase 3 INO-VATE trial revealed that patients with relapsed/refractory ALL who received inotuzumab ozogamicin were less likely to receive subsequent salvage therapy than those who received standard...
True or False: Findings from the...
08/05/2022
Oncology