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Acute Myeloid Leukemia Specialty Channel

Acute Myeloid Leukemia
Specialty Channel
Quiz
01/12/2026
True or false: Following allogeneic hematopoietic stem cell transplantation, dual epigenetic maintenance therapy with chidamide and azacitidine demonstrated promising activity and acceptable tolerability for patients with high-risk acute...
True or false: Following allogeneic hematopoietic stem cell transplantation, dual epigenetic maintenance therapy with chidamide and azacitidine demonstrated promising activity and acceptable tolerability for patients with high-risk acute...
True or false: Following...
01/12/2026
Oncology
News
01/12/2026
Emily Estrada
The combination of decitabine and cedazuridine maintenance therapy demonstrated promising activity with manageable toxicity for patients with very high-risk acute myeloid leukemia or myelodysplastic syndrome.
The combination of decitabine and cedazuridine maintenance therapy demonstrated promising activity with manageable toxicity for patients with very high-risk acute myeloid leukemia or myelodysplastic syndrome.
The combination of decitabine...
01/12/2026
Oncology
News
01/12/2026
Emily Estrada
The combination of venetoclax and chidamide, azacitidine, cytarabine, aclarubicin, G-CSF therapy demonstrated high complete response rates, encouraging 1-year survival outcomes, and manageable toxicity for patients with R/R AML.
The combination of venetoclax and chidamide, azacitidine, cytarabine, aclarubicin, G-CSF therapy demonstrated high complete response rates, encouraging 1-year survival outcomes, and manageable toxicity for patients with R/R AML.
The combination of venetoclax...
01/12/2026
Oncology
Quiz
12/01/2025
True or False: According to results from the ENAVEN-AML trial, the combination of enasidenib and venetoclax showed encouraging clinical activity and a manageable safety profile among patients with R/R acute myeloid leukemia and an IDH2...
True or False: According to results from the ENAVEN-AML trial, the combination of enasidenib and venetoclax showed encouraging clinical activity and a manageable safety profile among patients with R/R acute myeloid leukemia and an IDH2...
True or False: According to...
12/01/2025
Oncology
News
12/01/2025
Emily Estrada
The combination of chidamide and azacitidine after allogeneic hematopoietic stem cell transplantation for patients with high-risk acute myeloid leukemia demonstrated potential efficacy and acceptable toxicity in a phase 2 trial.
The combination of chidamide and azacitidine after allogeneic hematopoietic stem cell transplantation for patients with high-risk acute myeloid leukemia demonstrated potential efficacy and acceptable toxicity in a phase 2 trial.
The combination of chidamide and...
12/01/2025
Oncology
News
12/01/2025
Emily Estrada
Among patients with acute myeloid leukemia in first remission, autoSCT showed significantly improved relapse-free and overall survival compared with chemotherapy according to a real-world, retrospective study.
Among patients with acute myeloid leukemia in first remission, autoSCT showed significantly improved relapse-free and overall survival compared with chemotherapy according to a real-world, retrospective study.
Among patients with acute...
12/01/2025
Oncology
FDA Approval
11/13/2025
Emily Estrada
The FDA approved ziftomenib, a menin inhibitor, for patients with relapsed/refractory acute myeloid leukemia who have an NPM1 mutation and have no satisfactory alternative treatment options.
The FDA approved ziftomenib, a menin inhibitor, for patients with relapsed/refractory acute myeloid leukemia who have an NPM1 mutation and have no satisfactory alternative treatment options.
The FDA approved ziftomenib, a...
11/13/2025
Oncology
Quiz
10/30/2025
Emily Estrada
True or False: Venetoclax combined with azacitidine demonstrated poor clinical responses with unmanageable toxicity for elderly patients with relapsed acute myeloid leukemia, based on results from a single-center retrospective study.
True or False: Venetoclax combined with azacitidine demonstrated poor clinical responses with unmanageable toxicity for elderly patients with relapsed acute myeloid leukemia, based on results from a single-center retrospective study.
True or False: Venetoclax...
10/30/2025
Oncology
News
10/30/2025
Emily Estrada
According to results from the ENAVEN-AML trial, enasidenib combined with venetoclax demonstrated clinical activity and manageable safety for R/R IDH2-mutated acute myeloid leukemia.
According to results from the ENAVEN-AML trial, enasidenib combined with venetoclax demonstrated clinical activity and manageable safety for R/R IDH2-mutated acute myeloid leukemia.
According to results from the...
10/30/2025
Oncology
FDA Approval
10/24/2025
Emily Estrada
The US Food and Drug Administration has approved revumenib for the treatment of relapsed/refractory acute myeloid leukemia for patients with an NPM1 mutation.
The US Food and Drug Administration has approved revumenib for the treatment of relapsed/refractory acute myeloid leukemia for patients with an NPM1 mutation.
The US Food and Drug...
10/24/2025
Oncology
Quiz
10/02/2025
True or False: Patients with concurrent DNMT3A and TET2 mutations and acute myeloid leukemia demonstrated superior treatment responses and survival outcomes compared to patients without mutations, according to a retrospective analysis.
True or False: Patients with concurrent DNMT3A and TET2 mutations and acute myeloid leukemia demonstrated superior treatment responses and survival outcomes compared to patients without mutations, according to a retrospective analysis.
True or False: Patients with...
10/02/2025
Oncology

News

News
01/12/2026
Emily Estrada
The combination of decitabine and cedazuridine maintenance therapy demonstrated promising activity with manageable toxicity for patients with very high-risk acute myeloid leukemia or myelodysplastic syndrome.
The combination of decitabine and cedazuridine maintenance therapy demonstrated promising activity with manageable toxicity for patients with very high-risk acute myeloid leukemia or myelodysplastic syndrome.
The combination of decitabine...
01/12/2026
Oncology
News
01/12/2026
Emily Estrada
The combination of venetoclax and chidamide, azacitidine, cytarabine, aclarubicin, G-CSF therapy demonstrated high complete response rates, encouraging 1-year survival outcomes, and manageable toxicity for patients with R/R AML.
The combination of venetoclax and chidamide, azacitidine, cytarabine, aclarubicin, G-CSF therapy demonstrated high complete response rates, encouraging 1-year survival outcomes, and manageable toxicity for patients with R/R AML.
The combination of venetoclax...
01/12/2026
Oncology
News
12/01/2025
Emily Estrada
The combination of chidamide and azacitidine after allogeneic hematopoietic stem cell transplantation for patients with high-risk acute myeloid leukemia demonstrated potential efficacy and acceptable toxicity in a phase 2 trial.
The combination of chidamide and azacitidine after allogeneic hematopoietic stem cell transplantation for patients with high-risk acute myeloid leukemia demonstrated potential efficacy and acceptable toxicity in a phase 2 trial.
The combination of chidamide and...
12/01/2025
Oncology
News
12/01/2025
Emily Estrada
Among patients with acute myeloid leukemia in first remission, autoSCT showed significantly improved relapse-free and overall survival compared with chemotherapy according to a real-world, retrospective study.
Among patients with acute myeloid leukemia in first remission, autoSCT showed significantly improved relapse-free and overall survival compared with chemotherapy according to a real-world, retrospective study.
Among patients with acute...
12/01/2025
Oncology
FDA Approval
11/13/2025
Emily Estrada
The FDA approved ziftomenib, a menin inhibitor, for patients with relapsed/refractory acute myeloid leukemia who have an NPM1 mutation and have no satisfactory alternative treatment options.
The FDA approved ziftomenib, a menin inhibitor, for patients with relapsed/refractory acute myeloid leukemia who have an NPM1 mutation and have no satisfactory alternative treatment options.
The FDA approved ziftomenib, a...
11/13/2025
Oncology
News
10/30/2025
Emily Estrada
According to results from the ENAVEN-AML trial, enasidenib combined with venetoclax demonstrated clinical activity and manageable safety for R/R IDH2-mutated acute myeloid leukemia.
According to results from the ENAVEN-AML trial, enasidenib combined with venetoclax demonstrated clinical activity and manageable safety for R/R IDH2-mutated acute myeloid leukemia.
According to results from the...
10/30/2025
Oncology
FDA Approval
10/24/2025
Emily Estrada
The US Food and Drug Administration has approved revumenib for the treatment of relapsed/refractory acute myeloid leukemia for patients with an NPM1 mutation.
The US Food and Drug Administration has approved revumenib for the treatment of relapsed/refractory acute myeloid leukemia for patients with an NPM1 mutation.
The US Food and Drug...
10/24/2025
Oncology
News
10/02/2025
Emily Estrada
According to a phase 2 trial, a PD-1 inhibitor combined with azacitidine and homoharringtonine, cytarabine, and G-CSF therapy demonstrated promising efficacy and safety among patients with relapsed/refractory acute myeloid leukemia.
According to a phase 2 trial, a PD-1 inhibitor combined with azacitidine and homoharringtonine, cytarabine, and G-CSF therapy demonstrated promising efficacy and safety among patients with relapsed/refractory acute myeloid leukemia.
According to a phase 2 trial, a...
10/02/2025
Oncology
News
10/02/2025
Emily Estrada
Additional ruxolitinib to decitabine with modified busulfan/cyclophosphamide therapy, showed promising relapse reduction and tolerability for high-risk acute myeloid leukemia and myelodysplastic syndrome with increased blasts treatment.
Additional ruxolitinib to decitabine with modified busulfan/cyclophosphamide therapy, showed promising relapse reduction and tolerability for high-risk acute myeloid leukemia and myelodysplastic syndrome with increased blasts treatment.
Additional ruxolitinib to...
10/02/2025
Oncology
News
10/02/2025
Emily Estrada
For patients over the age of 65 years with relapsed acute myeloid leukemia, including those with adverse cytogenetic features, the combination of venetoclax and azacitidine demonstrated promising clinical activity and manageable safety.
For patients over the age of 65 years with relapsed acute myeloid leukemia, including those with adverse cytogenetic features, the combination of venetoclax and azacitidine demonstrated promising clinical activity and manageable safety.
For patients over the age of 65...
10/02/2025
Oncology

Interactive Features

Quiz
01/12/2026
True or false: Following allogeneic hematopoietic stem cell transplantation, dual epigenetic maintenance therapy with chidamide and azacitidine demonstrated promising activity and acceptable tolerability for patients with high-risk acute...
True or false: Following allogeneic hematopoietic stem cell transplantation, dual epigenetic maintenance therapy with chidamide and azacitidine demonstrated promising activity and acceptable tolerability for patients with high-risk acute...
True or false: Following...
01/12/2026
Oncology
Quiz
12/01/2025
True or False: According to results from the ENAVEN-AML trial, the combination of enasidenib and venetoclax showed encouraging clinical activity and a manageable safety profile among patients with R/R acute myeloid leukemia and an IDH2...
True or False: According to results from the ENAVEN-AML trial, the combination of enasidenib and venetoclax showed encouraging clinical activity and a manageable safety profile among patients with R/R acute myeloid leukemia and an IDH2...
True or False: According to...
12/01/2025
Oncology
Quiz
10/30/2025
Emily Estrada
True or False: Venetoclax combined with azacitidine demonstrated poor clinical responses with unmanageable toxicity for elderly patients with relapsed acute myeloid leukemia, based on results from a single-center retrospective study.
True or False: Venetoclax combined with azacitidine demonstrated poor clinical responses with unmanageable toxicity for elderly patients with relapsed acute myeloid leukemia, based on results from a single-center retrospective study.
True or False: Venetoclax...
10/30/2025
Oncology
Quiz
10/02/2025
True or False: Patients with concurrent DNMT3A and TET2 mutations and acute myeloid leukemia demonstrated superior treatment responses and survival outcomes compared to patients without mutations, according to a retrospective analysis.
True or False: Patients with concurrent DNMT3A and TET2 mutations and acute myeloid leukemia demonstrated superior treatment responses and survival outcomes compared to patients without mutations, according to a retrospective analysis.
True or False: Patients with...
10/02/2025
Oncology
Quiz
08/25/2025
True or False: In a phase 1b/2 trial evaluating the efficacy and safety of venetoclax plus CPX-531 for the treatment of R/R acute myeloid leukemia, the combination therapy showed promising clinical activity, especially among patients in...
True or False: In a phase 1b/2 trial evaluating the efficacy and safety of venetoclax plus CPX-531 for the treatment of R/R acute myeloid leukemia, the combination therapy showed promising clinical activity, especially among patients in...
True or False: In a phase 1b/2...
08/25/2025
Oncology
Quiz
08/13/2025
True or False: According to results from the phase 2 KOMET-001 trial, ziftomenib demonstrated promising efficacy and safety among patients with relapsed/refractory NPM1-mutated acute myeloid leukemia.
True or False: According to results from the phase 2 KOMET-001 trial, ziftomenib demonstrated promising efficacy and safety among patients with relapsed/refractory NPM1-mutated acute myeloid leukemia.
True or False: According to...
08/13/2025
Oncology
Quiz
07/17/2025
In the post hoc analysis evaluating olutasidenib for R/R IDH1-mutant AML, patients treated earlier in the treatment sequence (after 1 to 2 prior regimens) demonstrated which overall response rate?
In the post hoc analysis evaluating olutasidenib for R/R IDH1-mutant AML, patients treated earlier in the treatment sequence (after 1 to 2 prior regimens) demonstrated which overall response rate?
In the post hoc analysis...
07/17/2025
Oncology
Quiz
06/16/2025
In an expanded phase 2 trial evaluating the addition of tislelizumab to a HMA plus CAG chemotherapy regimen for patients with high-risk R/R acute myeloid leukemia, what was the reported overall response rate in the group treated with...
In an expanded phase 2 trial evaluating the addition of tislelizumab to a HMA plus CAG chemotherapy regimen for patients with high-risk R/R acute myeloid leukemia, what was the reported overall response rate in the group treated with...
In an expanded phase 2 trial...
06/16/2025
Oncology
Quiz
09/25/2024
True or False: According to results from the phase 2a, dose-finding ALICE study, the frontline combination of iadademstat and azacitidine failed to produce promising responses among patients with newly diagnosed acute myeloid leukemia,...
True or False: According to results from the phase 2a, dose-finding ALICE study, the frontline combination of iadademstat and azacitidine failed to produce promising responses among patients with newly diagnosed acute myeloid leukemia,...
True or False: According to...
09/25/2024
Oncology
Quiz
03/05/2024
True or False: Aspacytarabine demonstrated efficacy and safety among patients with acute myeloid leukemia who were young and fit for intensive chemotherapy, according to a phase 2b trial.
True or False: Aspacytarabine demonstrated efficacy and safety among patients with acute myeloid leukemia who were young and fit for intensive chemotherapy, according to a phase 2b trial.
True or False: Aspacytarabine...
03/05/2024
Oncology