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Brain Cancer Specialty Channel

News
08/27/2025
Stephanie Holland
According to results from a phase 1b study, clostridium novyi-nontoxic plus pembrolizumab demonstrated clinical promise among patients with treatment-refractory advanced solid tumors.
According to results from a phase 1b study, clostridium novyi-nontoxic plus pembrolizumab demonstrated clinical promise among patients with treatment-refractory advanced solid tumors.
According to results from a...
08/27/2025
Oncology
Quiz
08/14/2025
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma. Biomarker analyses revealed which of the following...
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma. Biomarker analyses revealed which of the following...
According to results from an...
08/14/2025
Oncology
News
08/07/2025
Stephanie Holland
Study results demonstrated that curative pencil beam scanning proton therapy demonstrated promising long-term efficacy and safety among children and adolescent/young adult patients with chordomas or chondrosarcomas.
Study results demonstrated that curative pencil beam scanning proton therapy demonstrated promising long-term efficacy and safety among children and adolescent/young adult patients with chordomas or chondrosarcomas.
Study results demonstrated that...
08/07/2025
Oncology
News
08/04/2025
Stephanie Holland
According to final results from the NCT PMO-1601 trial, palbociclib monotherapy demonstrated modest clinical activity among patients with locally advanced or metastatic chordoma.
According to final results from the NCT PMO-1601 trial, palbociclib monotherapy demonstrated modest clinical activity among patients with locally advanced or metastatic chordoma.
According to final results from...
08/04/2025
Oncology
Quiz
07/29/2025
True or False: According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
True or False: According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
True or False: According to...
07/29/2025
Oncology
News
07/23/2025
Stephanie Holland
According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
According to results from the...
07/23/2025
Oncology
News
07/22/2025
Stephanie Holland
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma.
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma.
According to results from an...
07/22/2025
Oncology
Conference Coverage
07/08/2025
Stephanie Holland
According to results from the phase 3 CATNON trial, concurrent temozolomide plus radiotherapy did not improve survival results compared to adjuvant temozolomide plus radiotherapy among patients without 1p/19p codeletion anaplastic glioma.
According to results from the phase 3 CATNON trial, concurrent temozolomide plus radiotherapy did not improve survival results compared to adjuvant temozolomide plus radiotherapy among patients without 1p/19p codeletion anaplastic glioma.
According to results from the...
07/08/2025
Oncology
Conference Coverage
07/01/2025
Stephanie Holland
According to results from a phase 1/2 study, dordaviprone demonstrated clinical promise and safety among adult and pediatric patients with recurrent H3 K27M-mutated diffuse glioma.
According to results from a phase 1/2 study, dordaviprone demonstrated clinical promise and safety among adult and pediatric patients with recurrent H3 K27M-mutated diffuse glioma.
According to results from a...
07/01/2025
Oncology
FDA Approval
05/14/2025
Allison Casey
On May 14, 2025, the US Food and Drug Administration approved belzutifan for the treatment of adult and pediatric patients 12 years and older with locally advanced, unresectable, or metastatic pheochromocytoma or paraganglioma.
On May 14, 2025, the US Food and Drug Administration approved belzutifan for the treatment of adult and pediatric patients 12 years and older with locally advanced, unresectable, or metastatic pheochromocytoma or paraganglioma.
On May 14, 2025, the US Food and...
05/14/2025
Oncology
News
02/11/2025
Allison Casey
A retrospective study compared outcomes among pediatric and adult patients with central nervous system tumors with NTRK gene fusion based on tumor histology and type of treatment.
A retrospective study compared outcomes among pediatric and adult patients with central nervous system tumors with NTRK gene fusion based on tumor histology and type of treatment.
A retrospective study compared...
02/11/2025
Oncology

News

News
08/27/2025
Stephanie Holland
According to results from a phase 1b study, clostridium novyi-nontoxic plus pembrolizumab demonstrated clinical promise among patients with treatment-refractory advanced solid tumors.
According to results from a phase 1b study, clostridium novyi-nontoxic plus pembrolizumab demonstrated clinical promise among patients with treatment-refractory advanced solid tumors.
According to results from a...
08/27/2025
Oncology
News
08/07/2025
Stephanie Holland
Study results demonstrated that curative pencil beam scanning proton therapy demonstrated promising long-term efficacy and safety among children and adolescent/young adult patients with chordomas or chondrosarcomas.
Study results demonstrated that curative pencil beam scanning proton therapy demonstrated promising long-term efficacy and safety among children and adolescent/young adult patients with chordomas or chondrosarcomas.
Study results demonstrated that...
08/07/2025
Oncology
News
08/04/2025
Stephanie Holland
According to final results from the NCT PMO-1601 trial, palbociclib monotherapy demonstrated modest clinical activity among patients with locally advanced or metastatic chordoma.
According to final results from the NCT PMO-1601 trial, palbociclib monotherapy demonstrated modest clinical activity among patients with locally advanced or metastatic chordoma.
According to final results from...
08/04/2025
Oncology
News
07/23/2025
Stephanie Holland
According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
According to results from the...
07/23/2025
Oncology
News
07/22/2025
Stephanie Holland
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma.
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma.
According to results from an...
07/22/2025
Oncology
Conference Coverage
07/08/2025
Stephanie Holland
According to results from the phase 3 CATNON trial, concurrent temozolomide plus radiotherapy did not improve survival results compared to adjuvant temozolomide plus radiotherapy among patients without 1p/19p codeletion anaplastic glioma.
According to results from the phase 3 CATNON trial, concurrent temozolomide plus radiotherapy did not improve survival results compared to adjuvant temozolomide plus radiotherapy among patients without 1p/19p codeletion anaplastic glioma.
According to results from the...
07/08/2025
Oncology
Conference Coverage
07/01/2025
Stephanie Holland
According to results from a phase 1/2 study, dordaviprone demonstrated clinical promise and safety among adult and pediatric patients with recurrent H3 K27M-mutated diffuse glioma.
According to results from a phase 1/2 study, dordaviprone demonstrated clinical promise and safety among adult and pediatric patients with recurrent H3 K27M-mutated diffuse glioma.
According to results from a...
07/01/2025
Oncology
News
02/11/2025
Allison Casey
A retrospective study compared outcomes among pediatric and adult patients with central nervous system tumors with NTRK gene fusion based on tumor histology and type of treatment.
A retrospective study compared outcomes among pediatric and adult patients with central nervous system tumors with NTRK gene fusion based on tumor histology and type of treatment.
A retrospective study compared...
02/11/2025
Oncology
News
06/14/2024

Stephanie Holland 

Stephanie Holland 
Based on results from the phase 1/2 TRIDENT-1 study, the US FDA has granted accelerated approval to repotrectinib for adult and pediatric patients 12 years and older with NRTK gene fusion-positive solid tumors.
Based on results from the phase 1/2 TRIDENT-1 study, the US FDA has granted accelerated approval to repotrectinib for adult and pediatric patients 12 years and older with NRTK gene fusion-positive solid tumors.
Based on results from the phase...
06/14/2024
Oncology
News
04/25/2024

Stephanie Holland 

Stephanie Holland 
Based on results from the FIREFLY-1 trial, the FDA has granted accelerated approval to tovorafenib for patients aged 6 months and older with relapsed or refractory pediatric low-grade glioma harboring a BRAF fusion, rearrangement, or a BRAF...
Based on results from the FIREFLY-1 trial, the FDA has granted accelerated approval to tovorafenib for patients aged 6 months and older with relapsed or refractory pediatric low-grade glioma harboring a BRAF fusion, rearrangement, or a BRAF...
Based on results from the...
04/25/2024
Oncology

Interactive Features

Quiz
08/14/2025
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma. Biomarker analyses revealed which of the following...
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma. Biomarker analyses revealed which of the following...
According to results from an...
08/14/2025
Oncology
Quiz
07/29/2025
True or False: According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
True or False: According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
True or False: According to...
07/29/2025
Oncology
Test Your Knowledge
01/12/2021
True or False: Although the combination of neurosurgical resection and postoperative HSRT is an emerging therapeutic approach for brain metastases, mature large-scale outcome data is currently lacking.
True or False: Although the combination of neurosurgical resection and postoperative HSRT is an emerging therapeutic approach for brain metastases, mature large-scale outcome data is currently lacking.
True or False: Although the...
01/12/2021
Oncology