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Brain Cancer Specialty Channel

News
10/28/2025
Janelle Bradley
In the phase 2 ALPHAMEDIX 02 trial, 212Pb-DOTAMTATE produced a 57% objective response rate and durable disease control with a favorable safety profile in PRRT-naïve patients with advanced somatostatin receptor-positive GEP-NETs.
In the phase 2 ALPHAMEDIX 02 trial, 212Pb-DOTAMTATE produced a 57% objective response rate and durable disease control with a favorable safety profile in PRRT-naïve patients with advanced somatostatin receptor-positive GEP-NETs.
In the phase 2 ALPHAMEDIX 02...
10/28/2025
Radiopharmaceutical Education Institute
From Radiopharmaceutical Education Institute
News
10/20/2025
Janelle Bradley
The somatostatin receptor–targeted alpha therapy 212Pb-DOTAMTATE achieved durable, clinically meaningful responses and favorable survival outcomes in patients with unresectable or metastatic GEP-NETs naïve to peptide receptor radionuclide...
The somatostatin receptor–targeted alpha therapy 212Pb-DOTAMTATE achieved durable, clinically meaningful responses and favorable survival outcomes in patients with unresectable or metastatic GEP-NETs naïve to peptide receptor radionuclide...
The somatostatin...
10/20/2025
Oncology
Mohamed Shebl Abdelbaki, MD, Washington University of Medicine in St Louis
Videos
10/07/2025
Mohamed Shebl Abdelbaki, MD
Mohamed Shebl Abdelbaki, MD, gives a presentation on the latest advances in pediatric low-grade glioma.
Mohamed Shebl Abdelbaki, MD, gives a presentation on the latest advances in pediatric low-grade glioma.
Mohamed Shebl Abdelbaki, MD,...
10/07/2025
Oncology
News
08/27/2025
Stephanie Holland
According to results from a phase 1b study, clostridium novyi-nontoxic plus pembrolizumab demonstrated clinical promise among patients with treatment-refractory advanced solid tumors.
According to results from a phase 1b study, clostridium novyi-nontoxic plus pembrolizumab demonstrated clinical promise among patients with treatment-refractory advanced solid tumors.
According to results from a...
08/27/2025
Oncology
Quiz
08/14/2025
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma. Biomarker analyses revealed which of the following...
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma. Biomarker analyses revealed which of the following...
According to results from an...
08/14/2025
Oncology
News
08/07/2025
Stephanie Holland
Study results demonstrated that curative pencil beam scanning proton therapy demonstrated promising long-term efficacy and safety among children and adolescent/young adult patients with chordomas or chondrosarcomas.
Study results demonstrated that curative pencil beam scanning proton therapy demonstrated promising long-term efficacy and safety among children and adolescent/young adult patients with chordomas or chondrosarcomas.
Study results demonstrated that...
08/07/2025
Oncology
News
08/04/2025
Stephanie Holland
According to final results from the NCT PMO-1601 trial, palbociclib monotherapy demonstrated modest clinical activity among patients with locally advanced or metastatic chordoma.
According to final results from the NCT PMO-1601 trial, palbociclib monotherapy demonstrated modest clinical activity among patients with locally advanced or metastatic chordoma.
According to final results from...
08/04/2025
Oncology
Quiz
07/29/2025
True or False: According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
True or False: According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
True or False: According to...
07/29/2025
Oncology
News
07/23/2025
Stephanie Holland
According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
According to results from the...
07/23/2025
Oncology
News
07/22/2025
Stephanie Holland
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma.
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma.
According to results from an...
07/22/2025
Oncology
Conference Coverage
07/08/2025
Stephanie Holland
According to results from the phase 3 CATNON trial, concurrent temozolomide plus radiotherapy did not improve survival results compared to adjuvant temozolomide plus radiotherapy among patients without 1p/19p codeletion anaplastic glioma.
According to results from the phase 3 CATNON trial, concurrent temozolomide plus radiotherapy did not improve survival results compared to adjuvant temozolomide plus radiotherapy among patients without 1p/19p codeletion anaplastic glioma.
According to results from the...
07/08/2025
Oncology

News

News
10/28/2025
Janelle Bradley
In the phase 2 ALPHAMEDIX 02 trial, 212Pb-DOTAMTATE produced a 57% objective response rate and durable disease control with a favorable safety profile in PRRT-naïve patients with advanced somatostatin receptor-positive GEP-NETs.
In the phase 2 ALPHAMEDIX 02 trial, 212Pb-DOTAMTATE produced a 57% objective response rate and durable disease control with a favorable safety profile in PRRT-naïve patients with advanced somatostatin receptor-positive GEP-NETs.
In the phase 2 ALPHAMEDIX 02...
10/28/2025
Radiopharmaceutical Education Institute
News
10/20/2025
Janelle Bradley
The somatostatin receptor–targeted alpha therapy 212Pb-DOTAMTATE achieved durable, clinically meaningful responses and favorable survival outcomes in patients with unresectable or metastatic GEP-NETs naïve to peptide receptor radionuclide...
The somatostatin receptor–targeted alpha therapy 212Pb-DOTAMTATE achieved durable, clinically meaningful responses and favorable survival outcomes in patients with unresectable or metastatic GEP-NETs naïve to peptide receptor radionuclide...
The somatostatin...
10/20/2025
Oncology
News
08/27/2025
Stephanie Holland
According to results from a phase 1b study, clostridium novyi-nontoxic plus pembrolizumab demonstrated clinical promise among patients with treatment-refractory advanced solid tumors.
According to results from a phase 1b study, clostridium novyi-nontoxic plus pembrolizumab demonstrated clinical promise among patients with treatment-refractory advanced solid tumors.
According to results from a...
08/27/2025
Oncology
News
08/07/2025
Stephanie Holland
Study results demonstrated that curative pencil beam scanning proton therapy demonstrated promising long-term efficacy and safety among children and adolescent/young adult patients with chordomas or chondrosarcomas.
Study results demonstrated that curative pencil beam scanning proton therapy demonstrated promising long-term efficacy and safety among children and adolescent/young adult patients with chordomas or chondrosarcomas.
Study results demonstrated that...
08/07/2025
Oncology
News
08/04/2025
Stephanie Holland
According to final results from the NCT PMO-1601 trial, palbociclib monotherapy demonstrated modest clinical activity among patients with locally advanced or metastatic chordoma.
According to final results from the NCT PMO-1601 trial, palbociclib monotherapy demonstrated modest clinical activity among patients with locally advanced or metastatic chordoma.
According to final results from...
08/04/2025
Oncology
News
07/23/2025
Stephanie Holland
According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
According to results from the...
07/23/2025
Oncology
News
07/22/2025
Stephanie Holland
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma.
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma.
According to results from an...
07/22/2025
Oncology
Conference Coverage
07/08/2025
Stephanie Holland
According to results from the phase 3 CATNON trial, concurrent temozolomide plus radiotherapy did not improve survival results compared to adjuvant temozolomide plus radiotherapy among patients without 1p/19p codeletion anaplastic glioma.
According to results from the phase 3 CATNON trial, concurrent temozolomide plus radiotherapy did not improve survival results compared to adjuvant temozolomide plus radiotherapy among patients without 1p/19p codeletion anaplastic glioma.
According to results from the...
07/08/2025
Oncology
Conference Coverage
07/01/2025
Stephanie Holland
According to results from a phase 1/2 study, dordaviprone demonstrated clinical promise and safety among adult and pediatric patients with recurrent H3 K27M-mutated diffuse glioma.
According to results from a phase 1/2 study, dordaviprone demonstrated clinical promise and safety among adult and pediatric patients with recurrent H3 K27M-mutated diffuse glioma.
According to results from a...
07/01/2025
Oncology
News
02/11/2025
Allison Casey
A retrospective study compared outcomes among pediatric and adult patients with central nervous system tumors with NTRK gene fusion based on tumor histology and type of treatment.
A retrospective study compared outcomes among pediatric and adult patients with central nervous system tumors with NTRK gene fusion based on tumor histology and type of treatment.
A retrospective study compared...
02/11/2025
Oncology

Interactive Features

Quiz
08/14/2025
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma. Biomarker analyses revealed which of the following...
According to results from an investigator-initiated phase 2 trial, camrelizumab plus apatinib demonstrated promising efficacy and safety among patients with advanced or refractory chordoma. Biomarker analyses revealed which of the following...
According to results from an...
08/14/2025
Oncology
Quiz
07/29/2025
True or False: According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
True or False: According to results from the phase 2 IMMUNOSARC trial, sunitinib plus nivolumab demonstrated promising efficacy and safety among patients with advanced extraskeletal myxoid chondrosarcoma.
True or False: According to...
07/29/2025
Oncology
Test Your Knowledge
01/12/2021
True or False: Although the combination of neurosurgical resection and postoperative HSRT is an emerging therapeutic approach for brain metastases, mature large-scale outcome data is currently lacking.
True or False: Although the combination of neurosurgical resection and postoperative HSRT is an emerging therapeutic approach for brain metastases, mature large-scale outcome data is currently lacking.
True or False: Although the...
01/12/2021
Oncology