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Metastatic Colorectal Cancer Specialty Channel

Metastatic Colorectal Cancer
Specialty Channel
News
09/22/2025
Stephanie Holland
According to results from the phase 2 E-BiTS study, intrapatient escalation of biweekly trifluridine/tipiracil plus bevacizumab demonstrated promising efficacy and safety among patients with advanced or unresectable metastatic colorectal...
According to results from the phase 2 E-BiTS study, intrapatient escalation of biweekly trifluridine/tipiracil plus bevacizumab demonstrated promising efficacy and safety among patients with advanced or unresectable metastatic colorectal...
According to results from the...
09/22/2025
Oncology
News
09/18/2025
Stephanie Holland
According to results from a real-world study, first-line FOLFOXIRI plus bevacizumab demonstrated improved efficacy compared to doublets plus bevacizumab among patients with initially unresectable, liver-only, right-sided and/or RAS or...
According to results from a real-world study, first-line FOLFOXIRI plus bevacizumab demonstrated improved efficacy compared to doublets plus bevacizumab among patients with initially unresectable, liver-only, right-sided and/or RAS or...
According to results from a...
09/18/2025
Oncology
News
08/26/2025
Stephanie Holland
According to results from the phase 2 EORTC 1560 trial, durvalumab and tremelimumab plus liver-directed partial local ablative treatment did not lead to radiological response in untreated metastases among patients with liver-predominant...
According to results from the phase 2 EORTC 1560 trial, durvalumab and tremelimumab plus liver-directed partial local ablative treatment did not lead to radiological response in untreated metastases among patients with liver-predominant...
According to results from the...
08/26/2025
Oncology
News
08/05/2025
Stephanie Holland
According to post hoc analysis results from the phase 3 SUNLIGHT trial, trifluridine and tipiracil plus bevacizumab improved tumor response compared to trifluridine and tipiracil alone among previously treated patients with metastatic...
According to post hoc analysis results from the phase 3 SUNLIGHT trial, trifluridine and tipiracil plus bevacizumab improved tumor response compared to trifluridine and tipiracil alone among previously treated patients with metastatic...
According to post hoc analysis...
08/05/2025
Oncology
Quiz
08/05/2025
True or False: According to updated results from the OrigAMI-1 trial, amivantamab rechallenge showed promising antitumor activity and lengthened survival end points among patients with left-sided metastatic colorectal cancer who underwent...
True or False: According to updated results from the OrigAMI-1 trial, amivantamab rechallenge showed promising antitumor activity and lengthened survival end points among patients with left-sided metastatic colorectal cancer who underwent...
True or False: According to...
08/05/2025
Oncology
Conference Coverage
08/05/2025
Stephanie Holland
According to results from the CheckMate 8HW trial, nivolumab plus ipilimumab significantly improved health-related quality of life compared to nivolumab alone among patients with microsatellite instability-high or mismatch repair-deficient...
According to results from the CheckMate 8HW trial, nivolumab plus ipilimumab significantly improved health-related quality of life compared to nivolumab alone among patients with microsatellite instability-high or mismatch repair-deficient...
According to results from the...
08/05/2025
Oncology
Conference Coverage
07/24/2025
Stephanie Holland
According to updated results from the OrigAMI-1 trial, amivantamab rechallenge showed promising antitumor activity and lengthened survival end points among patients who underwent rechallenge at least 9 months after EGFR inhibitor treatment.
According to updated results from the OrigAMI-1 trial, amivantamab rechallenge showed promising antitumor activity and lengthened survival end points among patients who underwent rechallenge at least 9 months after EGFR inhibitor treatment.
According to updated results...
07/24/2025
Oncology
Quiz
07/23/2025
True or False: According to results from the phase 1b CodeBreaK 101 study, sotorasib plus panitumumab and FOLFIRI demonstrated long-term efficacy and safety among patients with KRAS G12C-mutated metastatic colorectal cancer.
True or False: According to results from the phase 1b CodeBreaK 101 study, sotorasib plus panitumumab and FOLFIRI demonstrated long-term efficacy and safety among patients with KRAS G12C-mutated metastatic colorectal cancer.
True or False: According to...
07/23/2025
Oncology
News
07/23/2025
Stephanie Holland
According to final results from the phase 2 EurdaCT trial, mFOLFOX7 plus cetuximab followed by maintenance fluorouracil/folinic acid and cetuximab did not significantly improve outcomes among treatment-naive patients with RAS wild-type...
According to final results from the phase 2 EurdaCT trial, mFOLFOX7 plus cetuximab followed by maintenance fluorouracil/folinic acid and cetuximab did not significantly improve outcomes among treatment-naive patients with RAS wild-type...
According to final results from...
07/23/2025
Oncology
News
07/21/2025
Stephanie Holland
Results from a phase 2 trial highlight the impact of combining nivolumab with relatlimab on the tumor microenvironment among previously treated patients with unresectable or metastatic mismatch repair-proficient colorectal cancer.
Results from a phase 2 trial highlight the impact of combining nivolumab with relatlimab on the tumor microenvironment among previously treated patients with unresectable or metastatic mismatch repair-proficient colorectal cancer.
Results from a phase 2 trial...
07/21/2025
Oncology
News
07/11/2025
Stephanie Holland
According to results from a phase 3 trial, A140 plus mFOLFOX6 demonstrated encouraging efficacy and safety compared to cetuximab plus mFOLFOX6 among patients with RAS wild-type metastatic colorectal cancer.
According to results from a phase 3 trial, A140 plus mFOLFOX6 demonstrated encouraging efficacy and safety compared to cetuximab plus mFOLFOX6 among patients with RAS wild-type metastatic colorectal cancer.
According to results from a...
07/11/2025
Oncology

News

News
09/22/2025
Stephanie Holland
According to results from the phase 2 E-BiTS study, intrapatient escalation of biweekly trifluridine/tipiracil plus bevacizumab demonstrated promising efficacy and safety among patients with advanced or unresectable metastatic colorectal...
According to results from the phase 2 E-BiTS study, intrapatient escalation of biweekly trifluridine/tipiracil plus bevacizumab demonstrated promising efficacy and safety among patients with advanced or unresectable metastatic colorectal...
According to results from the...
09/22/2025
Oncology
News
09/18/2025
Stephanie Holland
According to results from a real-world study, first-line FOLFOXIRI plus bevacizumab demonstrated improved efficacy compared to doublets plus bevacizumab among patients with initially unresectable, liver-only, right-sided and/or RAS or...
According to results from a real-world study, first-line FOLFOXIRI plus bevacizumab demonstrated improved efficacy compared to doublets plus bevacizumab among patients with initially unresectable, liver-only, right-sided and/or RAS or...
According to results from a...
09/18/2025
Oncology
News
08/26/2025
Stephanie Holland
According to results from the phase 2 EORTC 1560 trial, durvalumab and tremelimumab plus liver-directed partial local ablative treatment did not lead to radiological response in untreated metastases among patients with liver-predominant...
According to results from the phase 2 EORTC 1560 trial, durvalumab and tremelimumab plus liver-directed partial local ablative treatment did not lead to radiological response in untreated metastases among patients with liver-predominant...
According to results from the...
08/26/2025
Oncology
News
08/05/2025
Stephanie Holland
According to post hoc analysis results from the phase 3 SUNLIGHT trial, trifluridine and tipiracil plus bevacizumab improved tumor response compared to trifluridine and tipiracil alone among previously treated patients with metastatic...
According to post hoc analysis results from the phase 3 SUNLIGHT trial, trifluridine and tipiracil plus bevacizumab improved tumor response compared to trifluridine and tipiracil alone among previously treated patients with metastatic...
According to post hoc analysis...
08/05/2025
Oncology
Conference Coverage
08/05/2025
Stephanie Holland
According to results from the CheckMate 8HW trial, nivolumab plus ipilimumab significantly improved health-related quality of life compared to nivolumab alone among patients with microsatellite instability-high or mismatch repair-deficient...
According to results from the CheckMate 8HW trial, nivolumab plus ipilimumab significantly improved health-related quality of life compared to nivolumab alone among patients with microsatellite instability-high or mismatch repair-deficient...
According to results from the...
08/05/2025
Oncology
Conference Coverage
07/24/2025
Stephanie Holland
According to updated results from the OrigAMI-1 trial, amivantamab rechallenge showed promising antitumor activity and lengthened survival end points among patients who underwent rechallenge at least 9 months after EGFR inhibitor treatment.
According to updated results from the OrigAMI-1 trial, amivantamab rechallenge showed promising antitumor activity and lengthened survival end points among patients who underwent rechallenge at least 9 months after EGFR inhibitor treatment.
According to updated results...
07/24/2025
Oncology
News
07/23/2025
Stephanie Holland
According to final results from the phase 2 EurdaCT trial, mFOLFOX7 plus cetuximab followed by maintenance fluorouracil/folinic acid and cetuximab did not significantly improve outcomes among treatment-naive patients with RAS wild-type...
According to final results from the phase 2 EurdaCT trial, mFOLFOX7 plus cetuximab followed by maintenance fluorouracil/folinic acid and cetuximab did not significantly improve outcomes among treatment-naive patients with RAS wild-type...
According to final results from...
07/23/2025
Oncology
News
07/21/2025
Stephanie Holland
Results from a phase 2 trial highlight the impact of combining nivolumab with relatlimab on the tumor microenvironment among previously treated patients with unresectable or metastatic mismatch repair-proficient colorectal cancer.
Results from a phase 2 trial highlight the impact of combining nivolumab with relatlimab on the tumor microenvironment among previously treated patients with unresectable or metastatic mismatch repair-proficient colorectal cancer.
Results from a phase 2 trial...
07/21/2025
Oncology
News
07/11/2025
Stephanie Holland
According to results from a phase 3 trial, A140 plus mFOLFOX6 demonstrated encouraging efficacy and safety compared to cetuximab plus mFOLFOX6 among patients with RAS wild-type metastatic colorectal cancer.
According to results from a phase 3 trial, A140 plus mFOLFOX6 demonstrated encouraging efficacy and safety compared to cetuximab plus mFOLFOX6 among patients with RAS wild-type metastatic colorectal cancer.
According to results from a...
07/11/2025
Oncology
News
07/09/2025
Stephanie Holland
According to updated interim analysis results from the phase 3 BREAKWATER trial, encorafenib plus cetuximab and mFOLFOX6 improved survival compared to standard of care among previously untreated patients with BRAF V600E-mutated metastatic...
According to updated interim analysis results from the phase 3 BREAKWATER trial, encorafenib plus cetuximab and mFOLFOX6 improved survival compared to standard of care among previously untreated patients with BRAF V600E-mutated metastatic...
According to updated interim...
07/09/2025
Oncology

Interactive Features

Quiz
08/05/2025
True or False: According to updated results from the OrigAMI-1 trial, amivantamab rechallenge showed promising antitumor activity and lengthened survival end points among patients with left-sided metastatic colorectal cancer who underwent...
True or False: According to updated results from the OrigAMI-1 trial, amivantamab rechallenge showed promising antitumor activity and lengthened survival end points among patients with left-sided metastatic colorectal cancer who underwent...
True or False: According to...
08/05/2025
Oncology
Quiz
07/23/2025
True or False: According to results from the phase 1b CodeBreaK 101 study, sotorasib plus panitumumab and FOLFIRI demonstrated long-term efficacy and safety among patients with KRAS G12C-mutated metastatic colorectal cancer.
True or False: According to results from the phase 1b CodeBreaK 101 study, sotorasib plus panitumumab and FOLFIRI demonstrated long-term efficacy and safety among patients with KRAS G12C-mutated metastatic colorectal cancer.
True or False: According to...
07/23/2025
Oncology