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Amer Zeidan, MBBS, MHS
Conference Coverage
Ziftomenib Plus Standard Induction Therapy Demonstrates Meaningful Clinical Activity for Patients With AML: KOMET-007
08/25/2025
Amer Zeidan, MBBS
At the EHA 2025 Congress, Amer Zeidan, MBBS, MHS, shared results from the KOMET-007 trial which evaluated the efficacy of ziftomenib combined with standard induction therapy for patients with newly diagnosed acute myeloid leukemia.
At the EHA 2025 Congress, Amer Zeidan, MBBS, MHS, shared results from the KOMET-007 trial which evaluated the efficacy of ziftomenib combined with standard induction therapy for patients with newly diagnosed acute myeloid leukemia.
At the EHA 2025 Congress, Amer...
08/25/2025
Oncology
Amer Zeidan, MBBS, MHS
Conference Coverage
Decitabine-Cedazuridine Plus Venetoclax Therapy Shows Efficacy and Safety for Patients With Newly Diagnosed AML
08/20/2025
Amer Zeidan, MBBS
Amer Zeidan, MBBS, MHS, shares results from a phase 2 trial determining the safety and efficacy of decitabine-cedazuridine plus venetoclax for patients with newly diagnosed acute myeloid leukemia ineligible for induction chemotherapy.
Amer Zeidan, MBBS, MHS, shares results from a phase 2 trial determining the safety and efficacy of decitabine-cedazuridine plus venetoclax for patients with newly diagnosed acute myeloid leukemia ineligible for induction chemotherapy.
Amer Zeidan, MBBS, MHS, shares...
08/20/2025
Oncology
Naval Daver, MD
Conference Coverage
Challenges of Applying MRD Decision-Making to Determine Transplant Among Patients With AML
08/05/2025
Naval G. Daver
At the 2025 Great Debates in Hematologic Malignancies meeting, Naval Daver, MD, debates against minimal residual disease negativity as the predominate determining factor for transplant eligibility among patients with acute myeloid leukemia.
At the 2025 Great Debates in Hematologic Malignancies meeting, Naval Daver, MD, debates against minimal residual disease negativity as the predominate determining factor for transplant eligibility among patients with acute myeloid leukemia.
At the 2025 Great Debates in...
08/05/2025
Oncology
Aaron Goldberg, MD, PhD
Conference Coverage
Optimizing Targeted and Genetic Therapeutic Strategies for Patients With R/R Acute Myeloid Leukemia
08/05/2025
At the 2025 Great Debates in Hematologic Malignancies meeting, Aaron Goldberg, MD, PhD, discussed evolving treatment strategies and therapies for patients with relapsed/ refractory acute myeloid leukemia.
At the 2025 Great Debates in Hematologic Malignancies meeting, Aaron Goldberg, MD, PhD, discussed evolving treatment strategies and therapies for patients with relapsed/ refractory acute myeloid leukemia.
At the 2025 Great Debates in...
08/05/2025
Oncology
Andrew Artz, MD, MS
Conference Coverage
Benefits of Utilizing MRD Negativity to Determine Transplant Eligibility for Patients With AML
08/05/2025
Andrew Artz, MD, MS, participated in a debate arguing for the benefits of utilizing minimal residual disease negativity as the primary marker for transplantation eligibility among patients with acute myeloid leukemia at the 2025 Great Debates...
Andrew Artz, MD, MS, participated in a debate arguing for the benefits of utilizing minimal residual disease negativity as the primary marker for transplantation eligibility among patients with acute myeloid leukemia at the 2025 Great Debates...
Andrew Artz, MD, MS,...
08/05/2025
Oncology
News
Patients With Acute Myeloid Leukemia and Concurrent DNMT3A and TET2 Mutations Demonstrate Lower Survival Outcomes
07/17/2025
Emily Estrada
Among elderly patients with AML, DNMT3A and TET2 mutations are associated with worse survival outcomes, while IDH1/IDH2 mutations are associated with improved survival, though these mutations were not found to significantly influence choice...
Among elderly patients with AML, DNMT3A and TET2 mutations are associated with worse survival outcomes, while IDH1/IDH2 mutations are associated with improved survival, though these mutations were not found to significantly influence choice...
Among elderly patients with AML,...
07/17/2025
Oncology
News
Venetoclax and CPX-531 Demonstrates Promising Activity Among Patients With Relapsed/Refractory Acute Myeloid Leukemia
07/10/2025
Emily Estrada
The combination of venetoclax with CPX-351, a liposome of cytarabine and daunorubicin, demonstrated clinical activity among patients with relapsed/refractory acute myeloid leukemia, according to results from a phase 2 trial.
The combination of venetoclax with CPX-351, a liposome of cytarabine and daunorubicin, demonstrated clinical activity among patients with relapsed/refractory acute myeloid leukemia, according to results from a phase 2 trial.
The combination of venetoclax...
07/10/2025
Oncology
Conference Coverage
Ziftomenib Achieves Durable Responses in R/R NPM1-Mutant AML Regardless of Prior Venetoclax Exposure: Pivotal KOMET-001 Results
06/12/2025
Emily Estrada
Ziftomenib monotherapy demonstrated deep and durable responses among patients with relapsed/refractory NPM1-mutated acute myeloid leukemia, according to a phase 1b/2 trial.
Ziftomenib monotherapy demonstrated deep and durable responses among patients with relapsed/refractory NPM1-mutated acute myeloid leukemia, according to a phase 1b/2 trial.
Ziftomenib monotherapy...
06/12/2025
Oncology
Conference Coverage
Ziftomenib Achieves Durable Responses in R/R NPM1-Mutant AML Regardless of Prior Venetoclax Exposure: Pivotal KOMET-001 Results
06/12/2025
Emily Estrada
Ziftomenib monotherapy demonstrated deep and durable responses among patients with relapsed/refractory NPM1-mutated acute myeloid leukemia, according to a phase 1b/2 trial.
Ziftomenib monotherapy demonstrated deep and durable responses among patients with relapsed/refractory NPM1-mutated acute myeloid leukemia, according to a phase 1b/2 trial.
Ziftomenib monotherapy...
06/12/2025
Oncology
Conference Coverage
Real-World Data Confirms CPX-351 Efficacy and Safety for Newly Diagnosed t-AML and AML-MRC, With Enhanced Outcomes in Younger Patients and MR-Mutated Disease
06/05/2025
Emily Estrada
Treatment with CPX-351 for patients with newly diagnosed secondary acute myeloid leukemia demonstrates real-world efficacy and safety, according to results from a retrospective study.
Treatment with CPX-351 for patients with newly diagnosed secondary acute myeloid leukemia demonstrates real-world efficacy and safety, according to results from a retrospective study.
Treatment with CPX-351 for...
06/05/2025
Oncology

Recent News

News
Genotype-Guided Therapy Demonstrates High Response and Survival Rates for Patients With R/R DLBCL
09/26/2025
Emily Estrada
The implementation of R-ICE combined with genotype-guided therapy for the treatment of relapsed/refractory diffuse large B-cell lymphoma demonstrated clinical efficacy and safety in a phase 2 trial.
The implementation of R-ICE combined with genotype-guided therapy for the treatment of relapsed/refractory diffuse large B-cell lymphoma demonstrated clinical efficacy and safety in a phase 2 trial.
The implementation of R-ICE...
09/26/2025
Oncology
News
PD-1/PD-L1 Inhibitor Monotherapy Demonstrates Accceptable Safety, Limited Efficacy for R/R DLBCL
09/26/2025
Emily Estrada
Treatment of R/R diffuse large B-cell lymphoma with PD-1/PD-L1 inhibitors alone showed consistent safety but limited efficacy, while combination treatment with CAR T-cell therapy demonstrated potential improved outcomes.
Treatment of R/R diffuse large B-cell lymphoma with PD-1/PD-L1 inhibitors alone showed consistent safety but limited efficacy, while combination treatment with CAR T-cell therapy demonstrated potential improved outcomes.
Treatment of R/R diffuse large...
09/26/2025
Oncology
News
Polatuzumab-Based Regimens Demonstrate Promising Efficacy for R/R DLBCL Compared to Traditional Salvage Therapies
09/26/2025
Emily Estrada
Compared with traditional salvage therapies, polatuzumab vedotin and zanubrutinib combined with rituximab or obinutuzumab demonstrated encouraging clinical efficacy for patients with relapsed/refractory diffuse large B-cell lymphoma.
Compared with traditional salvage therapies, polatuzumab vedotin and zanubrutinib combined with rituximab or obinutuzumab demonstrated encouraging clinical efficacy for patients with relapsed/refractory diffuse large B-cell lymphoma.
Compared with traditional...
09/26/2025
Oncology
FDA Approval
FDA Approves Imlunestrant for Patients With ER-Positive, HER2-Negative, ESR1-Mutated Advanced or Metastatic Breast Cancer
09/25/2025
Stephanie Holland
The FDA has approved imlunestrant for patients with ER-positive, HER2-negative advanced or metastatic breast cancer harboring ESR1 mutations.
The FDA has approved imlunestrant for patients with ER-positive, HER2-negative advanced or metastatic breast cancer harboring ESR1 mutations.
The FDA has approved...
09/25/2025
Oncology
News
Pexidartinib Shows Durable Response Among Patients with Tenosynovial Giant Cell Tumors
09/25/2025
Allison Casey
Pexidartinib showed sustained clinical benefit among patients with tenosynovial giant cell tumor associated with severe morbidity or functional limitations and not amenable to surgery.
Pexidartinib showed sustained clinical benefit among patients with tenosynovial giant cell tumor associated with severe morbidity or functional limitations and not amenable to surgery.
Pexidartinib showed sustained...
09/25/2025
Oncology
News
Clarithromycin-Based Quadruplet Therapy Demonstrates Promising Clinical Responses for Treatment of Relapsed/Refractory Multiple Myeloma
09/24/2025
Emily Estrada
For patients with relapsed/refractory multiple myeloma, the combination of clarithromycin, ixazomib, pomalidomide, and dexamethasone demonstrated promising clinical efficacy and a manageable safety profile.
For patients with relapsed/refractory multiple myeloma, the combination of clarithromycin, ixazomib, pomalidomide, and dexamethasone demonstrated promising clinical efficacy and a manageable safety profile.
For patients with...
09/24/2025
Oncology
News
First-Line mFOLFIRINOX, S-IROX Fail to Improve Survival Among Patients With Recurrent or Metastatic Pancreatic Cancer
09/23/2025
Stephanie Holland
Results from the phase 2/3 GENERATE study demonstrated that neither mFOLFIRINOX nor S-IROX improved survival results compared to nab-paclitaxel plus gemcitabine among patients with recurrent or metastatic pancreatic cancer in the first-line...
Results from the phase 2/3 GENERATE study demonstrated that neither mFOLFIRINOX nor S-IROX improved survival results compared to nab-paclitaxel plus gemcitabine among patients with recurrent or metastatic pancreatic cancer in the first-line...
Results from the phase 2/3...
09/23/2025
Oncology
News
Novel Anti-CSF1 Receptor Antibody for Patients With Tenosynovial Giant Cell Tumor
09/23/2025
Allison Casey
According to a phase 2a trial, the novel anti-CSF1 receptor monoclonal antibody, AMB-05X, was found to have favorable pharmacokinetics, pharmacodynamics, efficacy, and safety among patients with tenosynovial giant cell tumors.
According to a phase 2a trial, the novel anti-CSF1 receptor monoclonal antibody, AMB-05X, was found to have favorable pharmacokinetics, pharmacodynamics, efficacy, and safety among patients with tenosynovial giant cell tumors.
According to a phase 2a trial,...
09/23/2025
Oncology
News
Adverse Events With Pexidartinib for Patients With Tenosynovial Giant Cell Tumor
09/23/2025
Allison Casey
According to an analysis of the FDA Adverse Events Reporting System (FAERS) database, the overall safety profile of pexidartinib was generally consistent with the clinical trial findings.
According to an analysis of the FDA Adverse Events Reporting System (FAERS) database, the overall safety profile of pexidartinib was generally consistent with the clinical trial findings.
According to an analysis of the...
09/23/2025
Oncology
News
Trifluridine/Tipiracil Plus Bevacizumab Escalation Demonstrates Promise Among Patients With Advanced or Unresectable Metastatic Colorectal Cancer
09/22/2025
Stephanie Holland
According to results from the phase 2 E-BiTS study, intrapatient escalation of biweekly trifluridine/tipiracil plus bevacizumab demonstrated promising efficacy and safety among patients with advanced or unresectable metastatic colorectal...
According to results from the phase 2 E-BiTS study, intrapatient escalation of biweekly trifluridine/tipiracil plus bevacizumab demonstrated promising efficacy and safety among patients with advanced or unresectable metastatic colorectal...
According to results from the...
09/22/2025
Oncology

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