Contact
searchSearch
HMP Global
Clinical Videos

Video Supplement: Late Degeneration of a Transcatheter Aortic Valve Replacement Presenting With Flail Leaflet

Leila Alizadeh, MD
Maria Eleni Drosou, MD
Takayuki Onishi, MD
Roya Anahita Mousavi, MD
Amit Hooda, MD
Sahil Khera, MD, MPH
Lucy M. Safi, DO
George D. Dangas, MD, PhD
Gilbert H.L. Tang, MD, MSc, MBA
Samin K. Sharma, MD
Annapoorna S. Kini, MD
Stamatios Lerakis, MD, PhD
03/06/2026

Video. Transesophageal echocardiography showing flail aortic valve leaflet at the left coronary cusp, treated with a SAPIEN 3 Ultra Resilia (Edwards Lifesciences) within the Evolut valve, and displacing the flail leaflet against the aortic wall.

© 2026 HMP Global. All Rights Reserved.
Any views and opinions expressed are those of the author(s) and/or participants and do not necessarily reflect the views, policy, or position of the Journal of Invasive Cardiology or HMP Global, their employees, and affiliates. 
 


Related Content

Clinical Images
Late Degeneration of a Transcatheter Aortic Valve Replacement Presenting With Flail Leaflet
03/06/2026
Leila Alizadeh, MD; Maria Eleni Drosou, MD; Takayuki Onishi, MD; Roya Anahita Mousavi, MD; Amit Hooda, MD; Sahil Khera, MD, MPH; Lucy M. Safi, DO; George D. Dangas, MD, PhD; Gilbert H.L. Tang, MD, MSc, MBA; Samin K. Sharma, MD; Annapoorna S. Kini, MD; Stamatios Lerakis, MD, PhD
An 80-year-old man presented with dyspnea. Nine years earlier, he had undergone transcatheter aortic valve replacement with a 29-mm Evolut R self-expanding valve (Medtronic) following aborted surgical aortic valve replacement due to extensive...
An 80-year-old man presented with dyspnea. Nine years earlier, he had undergone transcatheter aortic valve replacement with a 29-mm Evolut R self-expanding valve (Medtronic) following aborted surgical aortic valve replacement due to extensive...
An 80-year-old man presented...
03/06/2026
Journal of Invasive Cardiology
Original Contribution
Cardiopulmonary Bypass is Safe and Effective Support for Concomitant High-Risk Percutaneous Coronary Intervention and Transcatheter Aortic Valve Replacement
02/23/2026
Axel Gomez, MD; Madison E. Matthews; Aaron Grober, MD; Ryan Ferreira, BS; Kendrick A. Shunk, MD, PhD; Jeffrey Zimmet, MD, PhD; Elaine E. Tseng, MD; Marko T. Boskovski, MD
The authors describe the procedural characteristics and short- and mid-term outcomes of 6 high-risk patients who underwent concomitant transcatheter aortic valve replacement and percutaneous coronary intervention under planned cardiopulmonary...
The authors describe the procedural characteristics and short- and mid-term outcomes of 6 high-risk patients who underwent concomitant transcatheter aortic valve replacement and percutaneous coronary intervention under planned cardiopulmonary...
The authors describe the...
02/23/2026
Journal of Invasive Cardiology
AI + ECG
Study Shows AccurKardia’s AI-Enabled ECG Can Detect Aortic Stenosis Years Before Valve Replacement and Improve Mortality Risk Prediction
02/11/2026
The study found that AK-AVS can detect aortic stenosis through routine ECGs up to 4.5 years before TAVR intervention, potentially enabling earlier detection, easier-to-access monitoring, and better timing of intervention.
The study found that AK-AVS can detect aortic stenosis through routine ECGs up to 4.5 years before TAVR intervention, potentially enabling earlier detection, easier-to-access monitoring, and better timing of intervention.
The study found that AK-AVS can...
02/11/2026
Cath Lab Digest
Original Contribution
Right Coronary Artery Takeoff Plane and Implications for Brachiocephalic Interventions and Next Generation Transcatheter Aortic Valve Intervention Embolic Protection Devices
02/09/2026
Umair Bajwa, MD; Mohammad Chaudhry, MD; Danielle Retcho, MD; Sohira Idrees, BA; Lukasz Partyka, MD; Rajiv Tayal, MD; Arash Salemi, MD; Sergio Waxman, MD; Najam Wasty, MD
The objective of this study was to determine if the right coronary artery takeoff is in the same plane as the takeoff plane of the major aortic arch branches.
The objective of this study was to determine if the right coronary artery takeoff is in the same plane as the takeoff plane of the major aortic arch branches.
The objective of this study was...
02/09/2026
Journal of Invasive Cardiology

News

Endovascular Devices
Thrombolex, Inc. Secures $50 Million Series A Growth Financing to Advance Commercialization of its Innovative Pharmaco-Mechanical Lysis Technology (PML)
03/19/2026
New Britain, PA, March 16, 2026 – Thrombolex, Inc., a commercial-stage medical device company advancing a differentiated pharmaco-mechanical lysis (PML) platform for the treatment of pulmonary embolism (PE) and other thromboembolic diseases,...
New Britain, PA, March 16, 2026 – Thrombolex, Inc., a commercial-stage medical device company advancing a differentiated pharmaco-mechanical lysis (PML) platform for the treatment of pulmonary embolism (PE) and other thromboembolic diseases,...
New Britain, PA, March 16, 2026...
03/19/2026
Vascular Disease Management
Rob Williamson, RAMPART CRO
Industry Leaders
RAMPART Appoints Rob Williamson as Chief Revenue Officer
02/12/2026
As Chief Revenue Officer, Rob Williamson will lead Rampart’s U.S. Sales organization, focusing on revenue growth, field execution, and team expansion.
As Chief Revenue Officer, Rob Williamson will lead Rampart’s U.S. Sales organization, focusing on revenue growth, field execution, and team expansion.
As Chief Revenue Officer, Rob...
02/12/2026
Cath Lab Digest
AI + ECG
Study Shows AccurKardia’s AI-Enabled ECG Can Detect Aortic Stenosis Years Before Valve Replacement and Improve Mortality Risk Prediction
02/11/2026
The study found that AK-AVS can detect aortic stenosis through routine ECGs up to 4.5 years before TAVR intervention, potentially enabling earlier detection, easier-to-access monitoring, and better timing of intervention.
The study found that AK-AVS can detect aortic stenosis through routine ECGs up to 4.5 years before TAVR intervention, potentially enabling earlier detection, easier-to-access monitoring, and better timing of intervention.
The study found that AK-AVS can...
02/11/2026
Cath Lab Digest
The Salus and Tallahassee Memorial HealthCare teams celebrate after the first AeroShield case.
Radiation Protection Systems
Tallahassee Memorial HealthCare Advances Cath Lab Safety Through First-in-the-World Technology Adoption
02/10/2026
Salus Scientific and Tallahassee Memorial HealthCare (TMH) announced the successful implementation and first clinical use of AeroShield™, a groundbreaking radiation protection technology developed by Salus Scientific.
Salus Scientific and Tallahassee Memorial HealthCare (TMH) announced the successful implementation and first clinical use of AeroShield™, a groundbreaking radiation protection technology developed by Salus Scientific.
Salus Scientific and Tallahassee...
02/10/2026
Cath Lab Digest
Thrombectomy
Avantec Vascular, a NIPRO Company, Announces FDA 510(k) Clearance of Thrombectomy System
02/10/2026
Sunnyvale, California – Avantec Vascular, a NIPRO Company, has received FDA 510(k) clearance for a thrombectomy system that will enable a new type of treatment for patients with thrombus in the peripheral venous...
Sunnyvale, California – Avantec Vascular, a NIPRO Company, has received FDA 510(k) clearance for a thrombectomy system that will enable a new type of treatment for patients with thrombus in the peripheral venous...
Sunnyvale, California...
02/10/2026
Cath Lab Digest
Heart Disease and Flu
Mount Sinai Scientists Uncover Link Between Influenza and Heart Disease
02/09/2026
New York, NY – Mount Sinai researchers have identified a cellular mechanism linking infections from influenza A viruses (IAVs) to cardiovascular disease, providing critical insights on how influenza can damage the heart and increase the risk...
New York, NY – Mount Sinai researchers have identified a cellular mechanism linking infections from influenza A viruses (IAVs) to cardiovascular disease, providing critical insights on how influenza can damage the heart and increase the risk...
New York, NY – Mount Sinai...
02/09/2026
Cath Lab Digest
Transseptal Access
AF Symposium 2026: New Data Show Atraverse Medical’s HOTWIRE™ System Mitigates Unintended Left Atrial Injury With Reduced RF Delivery
02/09/2026
The HOTWIRE™ Transseptal Access System combines a novel RF guidewire with a next-generation RF generator designed to optimize transseptal access, streamline procedural workflows and improve patient outcomes with the best-in-class platform for...
The HOTWIRE™ Transseptal Access System combines a novel RF guidewire with a next-generation RF generator designed to optimize transseptal access, streamline procedural workflows and improve patient outcomes with the best-in-class platform for...
The HOTWIRE™ Transseptal Access...
02/09/2026
EP Lab Digest
thrombectomy
Penumbra Launches Lightning Flash 3.0 — The Next Evolution in CAVT Technology
01/27/2026
Penumbra recently launched the Lightning Flash® 3.0 Computer Assisted Vacuum Thrombectomy (CAVT™) system, which includes significant upgrades that further advance our leading venous thromboembolism (VTE) platform.
Penumbra recently launched the Lightning Flash® 3.0 Computer Assisted Vacuum Thrombectomy (CAVT™) system, which includes significant upgrades that further advance our leading venous thromboembolism (VTE) platform.
Penumbra recently launched the...
01/27/2026
Cath Lab Digest
AI Cardiac Imaging Software
Study Reveals Stark Disconnect Between Americans’ Desire for Preventive Cardiac Screening and Care They Can Access
01/27/2026
New York, NY – In the lead-up to American Heart Health Month, a new national study reveals a stark disconnect between Americans’ desire for preventive cardiac screening and the care they can access. Despite heart disease remaining the leading...
New York, NY – In the lead-up to American Heart Health Month, a new national study reveals a stark disconnect between Americans’ desire for preventive cardiac screening and the care they can access. Despite heart disease remaining the leading...
New York, NY – In the lead-up to...
01/27/2026
Cath Lab Digest
Patent Foramen Ovale Detection
BURL Concepts Announces First Human Uses of FOQUS Ultrasound System for Patent Foramen Ovale (PFO) Detection
01/27/2026
The FOQUS ultrasound system, powered by SONAS technology, includes a transcranial headset system. The system introduces a new method to assist physicians in diagnosing a PFO, addressing the need for diagnostic tools that are both faster,...
The FOQUS ultrasound system, powered by SONAS technology, includes a transcranial headset system. The system introduces a new method to assist physicians in diagnosing a PFO, addressing the need for diagnostic tools that are both faster,...
The FOQUS ultrasound system,...
01/27/2026
Cath Lab Digest

JIC logo
CRT 2026
Early Clinical Experience and Outcomes With PFA for Atrial Fibrillation
03/20/2026
Laura Simson, MA
In this session from CRT 2026, Dr Nassir F. Marrouche of Tulane University presented the latest evidence positioning pulsed field ablation as a transformative advance in AF ablation.
In this session from CRT 2026, Dr Nassir F. Marrouche of Tulane University presented the latest evidence positioning pulsed field ablation as a transformative advance in AF ablation.
In this session from CRT 2026,...
03/20/2026
Journal of Invasive Cardiology
Endovascular Devices
Thrombolex, Inc. Secures $50 Million Series A Growth Financing to Advance Commercialization of its Innovative Pharmaco-Mechanical Lysis Technology (PML)
03/19/2026
New Britain, PA, March 16, 2026 – Thrombolex, Inc., a commercial-stage medical device company advancing a differentiated pharmaco-mechanical lysis (PML) platform for the treatment of pulmonary embolism (PE) and other thromboembolic diseases,...
New Britain, PA, March 16, 2026 – Thrombolex, Inc., a commercial-stage medical device company advancing a differentiated pharmaco-mechanical lysis (PML) platform for the treatment of pulmonary embolism (PE) and other thromboembolic diseases,...
New Britain, PA, March 16, 2026...
03/19/2026
Vascular Disease Management
ML Predicting AFib title slide
CRT 2026
Performance Of Machine Learning Models in Predicting Incident and Recurrent Atrial Fibrillation After Catheter Ablation — An Interview With Andreas Sarantopoulos, MD
03/18/2026
Andreas Sarantopoulos, MD
In this CRT 2026 interview, Dr Andreas Sarantopoulos of the NCH Rooney Heart Institute discusses his Top Abstract on machine learning for predicting recurrent atrial fibrillation and its implications for interventional cardiology practice.
In this CRT 2026 interview, Dr Andreas Sarantopoulos of the NCH Rooney Heart Institute discusses his Top Abstract on machine learning for predicting recurrent atrial fibrillation and its implications for interventional cardiology practice.
In this CRT 2026 interview, Dr...
03/18/2026
Journal of Invasive Cardiology
Eric A. Secemsky headshot
CRT 2026
Future Directions for RDN | From Hypertension to AFib and Beyond: 2026 Update
03/18/2026
Laura Simson, MA
In his session at CRT 2026, Dr Eric Secemsky reviewed contemporary data linking sympathetic overactivity to heart failure, atrial fibrillation, and cardiometabolic disease, and examined how renal and multi-organ denervation may modify these...
In his session at CRT 2026, Dr Eric Secemsky reviewed contemporary data linking sympathetic overactivity to heart failure, atrial fibrillation, and cardiometabolic disease, and examined how renal and multi-organ denervation may modify these...
In his session at CRT 2026, Dr...
03/18/2026
Journal of Invasive Cardiology
RDN for AFib title slide
CRT 2026
Future Directions for RDN | From Hypertension to AFib and Beyond: 2026 Update — An Interview With Eric A. Secemsky, MD, MSc
03/18/2026
Eric A. Secemsky, MD, MSc, RPVI, FACC, FAHA, FSCAI
In this interview from CRT 2026, Dr Eric A. Secemsky of Beth Israel Deaconess Medical Center speaks about the current status of renal denervation as a management strategy for atrial fibrillation and hypertension.
In this interview from CRT 2026, Dr Eric A. Secemsky of Beth Israel Deaconess Medical Center speaks about the current status of renal denervation as a management strategy for atrial fibrillation and hypertension.
In this interview from CRT 2026,...
03/18/2026
Journal of Invasive Cardiology
Sanjit Jolly_headshot
CRT 2026
Combined Left Atrial Appendage and OAC: The Next Frontier | LAAOS IV Trial
03/17/2026
Laura Simson, MA
At CRT 2026, Dr Sanjit S. Jolly of McMaster University presented the most recent developments in combination therapy for atrial fibrillation and the highly anticipated LAAOS IV trial.
At CRT 2026, Dr Sanjit S. Jolly of McMaster University presented the most recent developments in combination therapy for atrial fibrillation and the highly anticipated LAAOS IV trial.
At CRT 2026, Dr Sanjit S. Jolly...
03/17/2026
Journal of Invasive Cardiology
Neurovascular acquisitions
Medtronic to Acquire Scientia Vascular, Marrying Access and Therapeutic Portfolios for Neurovascular Care
03/11/2026
Scientia's novel access platform is designed to improve navigability through complex anatomy and simplify neurovascular procedures. By enabling faster and more reliable access, these technologies improve procedural efficiency.
Scientia's novel access platform is designed to improve navigability through complex anatomy and simplify neurovascular procedures. By enabling faster and more reliable access, these technologies improve procedural efficiency.
Scientia's novel access platform...
03/11/2026
Cath Lab Digest
CathWorks FFRangio
Fractional Flow Reserve
Late-Breaking Trial: U.S. Cohort of 4,000+ CathWorks FFRangio Patients Shows 2-Year Outcomes Comparable to Pressure Wire–Guided PCI
03/08/2026
"This first look at contemporary data of the growing adoption of angiography-derived physiology (ADP) in the U.S. shows similar clinical outcomes including death, MI and revascularization through 2 years when compared with invasive pressure...
"This first look at contemporary data of the growing adoption of angiography-derived physiology (ADP) in the U.S. shows similar clinical outcomes including death, MI and revascularization through 2 years when compared with invasive pressure...
"This first look at contemporary...
03/08/2026
Cath Lab Digest
Lerakis Figure. Transesophageal echocardiography of flail left coronary cusp
Clinical Videos
Video Supplement: Late Degeneration of a Transcatheter Aortic Valve Replacement Presenting With Flail Leaflet
03/06/2026
Leila Alizadeh, MD; Maria Eleni Drosou, MD; Takayuki Onishi, MD; Roya Anahita Mousavi, MD; Amit Hooda, MD; Sahil Khera, MD, MPH; Lucy M. Safi, DO; George D. Dangas, MD, PhD; Gilbert H.L. Tang, MD, MSc, MBA; Samin K. Sharma, MD; Annapoorna S. Kini, MD; Stamatios Lerakis, MD, PhD
Video Supplement to "Late Degeneration of a Transcatheter Aortic Valve Replacement Presenting With Flail Leaflet."
Video Supplement to "Late Degeneration of a Transcatheter Aortic Valve Replacement Presenting With Flail Leaflet."
Video Supplement to "Late...
03/06/2026
Journal of Invasive Cardiology
Clinical Images
Late Degeneration of a Transcatheter Aortic Valve Replacement Presenting With Flail Leaflet
03/06/2026
Leila Alizadeh, MD; Maria Eleni Drosou, MD; Takayuki Onishi, MD; Roya Anahita Mousavi, MD; Amit Hooda, MD; Sahil Khera, MD, MPH; Lucy M. Safi, DO; George D. Dangas, MD, PhD; Gilbert H.L. Tang, MD, MSc, MBA; Samin K. Sharma, MD; Annapoorna S. Kini, MD; Stamatios Lerakis, MD, PhD
An 80-year-old man presented with dyspnea. Nine years earlier, he had undergone transcatheter aortic valve replacement with a 29-mm Evolut R self-expanding valve (Medtronic) following aborted surgical aortic valve replacement due to extensive...
An 80-year-old man presented with dyspnea. Nine years earlier, he had undergone transcatheter aortic valve replacement with a 29-mm Evolut R self-expanding valve (Medtronic) following aborted surgical aortic valve replacement due to extensive...
An 80-year-old man presented...
03/06/2026
Journal of Invasive Cardiology

HMP Global Products

Events

HMP Education Logo
HMP Omnimedia Logo
HMP Europe Logo
© 2026 HMP Global. All Rights Reserved.
Cookie Policy Privacy Policy Terms of Use