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ctDNA Guided Adjuvant Therapy for Patients With Muscle-Invasive Bladder Cancer

03/14/2026


At Great Debates Solid Tumors in Miami, Florida, Guru Sonpavde, MD, from AdventHealth Cancer Institute in Orlando, Florida, discusses whether ctDNA-guided adjuvant therapy should be used in patients with high-risk muscle-invasive bladder cancer. 

Dr Sonpavde highlights emerging perioperative regimens such as enfortumab vedotin plus pembrolizumab and discusses whether ctDNA could help guide adjuvant therapy decisions in this patient population. 

Source:  

Sonpavde G. Optimizing immunotherapy strategies in muscle-invasive bladder cancer: Neoadjuvant IO-containing systemic therapy vs risk-adapted adjuvant IO. Presented at Great Debates - Solid Tumors; Miami, Florida. March 14-15, 2026. 

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Any views and opinions expressed are those of the author(s) and/or participants and do not necessarily reflect the views, policy, or position of Oncology Learning Network or HMP Global, their employees, and affiliates.

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