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Seizures & Epilepsy Topic Center

A head in profile with cogs coming out of it against an orange background
News
Less Than a Third of Patients With Focal Epilepsy Become Seizure-Free on First ASM
08/26/2025
Jolynn Tumolo
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly...
08/26/2025
Neurology
child sitting at a desk
News
Oseltamivir Reduces Risk of Serious Neuropsychiatric Events in Children During Influenza Episodes
08/13/2025
Maria Mantas
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was...
08/13/2025
Neurology
brain
News
Epilepsy Prevalence Higher in Frontotemporal Dementia Than Alzheimer Disease
06/23/2025
Jolynn Tumolo
Epilepsy diagnoses and the use of antiseizure medications were significantly higher among patients with frontotemporal dementia (FTD) compared with patients with Alzheimer disease (AD) and healthy controls in a case-control study.
Epilepsy diagnoses and the use of antiseizure medications were significantly higher among patients with frontotemporal dementia (FTD) compared with patients with Alzheimer disease (AD) and healthy controls in a case-control study.
Epilepsy diagnoses and the use...
06/23/2025
Neurology
rows of pill bottles
News
Cenobamate Shows Effectiveness in Real-World Patients With Drug-Resistant Epilepsy
05/21/2025
Jolynn Tumolo
Nearly half of real-world patients with drug-resistant epilepsy who received adjunctive cenobamate through an early access program experienced a 50% reduction in seizure frequency, according to recent findings.
Nearly half of real-world patients with drug-resistant epilepsy who received adjunctive cenobamate through an early access program experienced a 50% reduction in seizure frequency, according to recent findings.
Nearly half of real-world...
05/21/2025
Neurology
illustration of a test
Quiz
Which factors increase the risk of late-onset epilepsy (LOE) in people with cognitive decline?
04/23/2025
Maria Mantas
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors...
04/23/2025
Neurology
Neurons in the brain
News
Risk Factors for Late-Onset Epilepsy in Patients With Cognitive Decline Identified
04/21/2025
Jolynn Tumolo
Late-onset epilepsy (LOE) risk factors in people with cognitive decline include Parkinson disease, early-onset dementia (before age 60), poor cognition, stroke or transient ischemic attacks, Alzheimer disease, and the APOE4 allele.
Late-onset epilepsy (LOE) risk factors in people with cognitive decline include Parkinson disease, early-onset dementia (before age 60), poor cognition, stroke or transient ischemic attacks, Alzheimer disease, and the APOE4 allele.
Late-onset epilepsy (LOE) risk...
04/21/2025
Neurology
FDA approval stamp
News
FDA Approves Diazepam Nasal Spray for Children Aged 2 to 5 With Seizure Clusters
04/16/2025
Meagan Thistle
The FDA has expanded approval of immediate-use diazepam nasal spray as an acute treatment of intermittent, stereotypic episodes of frequent seizure activity—also known as seizure clusters or acute repetitive seizures—in pediatric patients...
The FDA has expanded approval of immediate-use diazepam nasal spray as an acute treatment of intermittent, stereotypic episodes of frequent seizure activity—also known as seizure clusters or acute repetitive seizures—in pediatric patients...
The FDA has expanded approval of...
04/16/2025
Neurology
illustrated brain with brain waves against a black background
News
Tool Gauges a Patient’s Epilepsy Status From a Single Normal EEG
03/12/2025
Jolynn Tumolo
A newly developed tool uses algorithms trained on dynamic network models to identify hidden markers of epilepsy from a single routine scalp electroencephalogram (EEG), according to a study published in the Annals of Neurology.
A newly developed tool uses algorithms trained on dynamic network models to identify hidden markers of epilepsy from a single routine scalp electroencephalogram (EEG), according to a study published in the Annals of Neurology.
A newly developed tool uses...
03/12/2025
Neurology
A new mom sits on the couch holding her infant, and her forehead
News
Gestational Hypertension, Preeclampsia, and Eclampsia Associated With Greater Incidence of Future Neurological Disorders
02/13/2025
Brionna Mendoza
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of...
02/13/2025
Neurology
Systematic Review Finds Problems With Epilepsy Outcome Prediction Models
News
Systematic Review Finds Problems With Epilepsy Outcome Prediction Models
10/10/2024
Jolynn Tumolo
Treatment outcome prediction models for patients with newly diagnosed epilepsy have a universally high risk of bias, researchers reported in a systematic review of nearly 50 such models published in the journal Epilepsia.
Treatment outcome prediction models for patients with newly diagnosed epilepsy have a universally high risk of bias, researchers reported in a systematic review of nearly 50 such models published in the journal Epilepsia.
Treatment outcome prediction...
10/10/2024
Neurology

Migraine CME Series

News

A head in profile with cogs coming out of it against an orange background
News
Less Than a Third of Patients With Focal Epilepsy Become Seizure-Free on First ASM
08/26/2025
Jolynn Tumolo
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly...
08/26/2025
Neurology
child sitting at a desk
News
Oseltamivir Reduces Risk of Serious Neuropsychiatric Events in Children During Influenza Episodes
08/13/2025
Maria Mantas
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was associated with a reduction in serious neuropsychiatric events in children and adolescents during influenza episodes, according to cohort study results published in JAMA Neurology. 
Oseltamivir treatment was...
08/13/2025
Neurology
brain
News
Epilepsy Prevalence Higher in Frontotemporal Dementia Than Alzheimer Disease
06/23/2025
Jolynn Tumolo
Epilepsy diagnoses and the use of antiseizure medications were significantly higher among patients with frontotemporal dementia (FTD) compared with patients with Alzheimer disease (AD) and healthy controls in a case-control study.
Epilepsy diagnoses and the use of antiseizure medications were significantly higher among patients with frontotemporal dementia (FTD) compared with patients with Alzheimer disease (AD) and healthy controls in a case-control study.
Epilepsy diagnoses and the use...
06/23/2025
Neurology
rows of pill bottles
News
Cenobamate Shows Effectiveness in Real-World Patients With Drug-Resistant Epilepsy
05/21/2025
Jolynn Tumolo
Nearly half of real-world patients with drug-resistant epilepsy who received adjunctive cenobamate through an early access program experienced a 50% reduction in seizure frequency, according to recent findings.
Nearly half of real-world patients with drug-resistant epilepsy who received adjunctive cenobamate through an early access program experienced a 50% reduction in seizure frequency, according to recent findings.
Nearly half of real-world...
05/21/2025
Neurology
Neurons in the brain
News
Risk Factors for Late-Onset Epilepsy in Patients With Cognitive Decline Identified
04/21/2025
Jolynn Tumolo
Late-onset epilepsy (LOE) risk factors in people with cognitive decline include Parkinson disease, early-onset dementia (before age 60), poor cognition, stroke or transient ischemic attacks, Alzheimer disease, and the APOE4 allele.
Late-onset epilepsy (LOE) risk factors in people with cognitive decline include Parkinson disease, early-onset dementia (before age 60), poor cognition, stroke or transient ischemic attacks, Alzheimer disease, and the APOE4 allele.
Late-onset epilepsy (LOE) risk...
04/21/2025
Neurology
FDA approval stamp
News
FDA Approves Diazepam Nasal Spray for Children Aged 2 to 5 With Seizure Clusters
04/16/2025
Meagan Thistle
The FDA has expanded approval of immediate-use diazepam nasal spray as an acute treatment of intermittent, stereotypic episodes of frequent seizure activity—also known as seizure clusters or acute repetitive seizures—in pediatric patients...
The FDA has expanded approval of immediate-use diazepam nasal spray as an acute treatment of intermittent, stereotypic episodes of frequent seizure activity—also known as seizure clusters or acute repetitive seizures—in pediatric patients...
The FDA has expanded approval of...
04/16/2025
Neurology
illustrated brain with brain waves against a black background
News
Tool Gauges a Patient’s Epilepsy Status From a Single Normal EEG
03/12/2025
Jolynn Tumolo
A newly developed tool uses algorithms trained on dynamic network models to identify hidden markers of epilepsy from a single routine scalp electroencephalogram (EEG), according to a study published in the Annals of Neurology.
A newly developed tool uses algorithms trained on dynamic network models to identify hidden markers of epilepsy from a single routine scalp electroencephalogram (EEG), according to a study published in the Annals of Neurology.
A newly developed tool uses...
03/12/2025
Neurology
A new mom sits on the couch holding her infant, and her forehead
News
Gestational Hypertension, Preeclampsia, and Eclampsia Associated With Greater Incidence of Future Neurological Disorders
02/13/2025
Brionna Mendoza
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of primiparous women found that those who experienced gestational hypertension, preeclampsia, and eclampsia were at increased risk for new-onset neurological disorders months or years after giving birth.
A recent Swedish cohort study of...
02/13/2025
Neurology
Systematic Review Finds Problems With Epilepsy Outcome Prediction Models
News
Systematic Review Finds Problems With Epilepsy Outcome Prediction Models
10/10/2024
Jolynn Tumolo
Treatment outcome prediction models for patients with newly diagnosed epilepsy have a universally high risk of bias, researchers reported in a systematic review of nearly 50 such models published in the journal Epilepsia.
Treatment outcome prediction models for patients with newly diagnosed epilepsy have a universally high risk of bias, researchers reported in a systematic review of nearly 50 such models published in the journal Epilepsia.
Treatment outcome prediction...
10/10/2024
Neurology
Sleep Disorders Linked With Epilepsy in Older Adults
News
Sleep Disorders Linked With Epilepsy in Older Adults
05/07/2024
Jolynn Tumolo
Sleep apnea and low oxygen levels during sleep are associated with late-onset epilepsy independently of hypertension and stroke, according to a study published online in the journal Sleep.
Sleep apnea and low oxygen levels during sleep are associated with late-onset epilepsy independently of hypertension and stroke, according to a study published online in the journal Sleep.
Sleep apnea and low oxygen...
05/07/2024
Neurology
two researchers look at computer screen in lab medical research
News
Apitegromab Improves Motor Function in Children With SMA
09/24/2025
Jolynn Tumolo
Treatment with the fully human monoclonal antibody apitegromab was associated with statistically significant improvements in motor function scores compared with placebo in patients with type 2 or type 3 spinal muscular atrophy (SMA).
Treatment with the fully human monoclonal antibody apitegromab was associated with statistically significant improvements in motor function scores compared with placebo in patients with type 2 or type 3 spinal muscular atrophy (SMA).
Treatment with the fully human...
09/24/2025
Neurology
a woman sits up in bed holding her head insomnia
News
Insomnia Linked With Cognitive Decline in Older Adults
09/23/2025
Jolynn Tumolo
Older adults with chronic insomnia were 40% more likely to develop mild cognitive impairment or dementia over a median 5.6 years compared with older adults without insomnia, according to a study published in Neurology.
Older adults with chronic insomnia were 40% more likely to develop mild cognitive impairment or dementia over a median 5.6 years compared with older adults without insomnia, according to a study published in Neurology.
Older adults with chronic...
09/23/2025
Neurology
an illustration of a head in profile with brain against a pink background
News
Noninvasive Physiomarker Identifies MCI and AD With High Accuracy
09/16/2025
Jolynn Tumolo
A novel physiological marker that quantifies the regulation dynamics of cerebral perfusion and oxygenation surpassed the performance of cognitive assessment tests and amyloid positron emission tomography (PET) in differentiating patients with...
A novel physiological marker that quantifies the regulation dynamics of cerebral perfusion and oxygenation surpassed the performance of cognitive assessment tests and amyloid positron emission tomography (PET) in differentiating patients with...
A novel physiological marker...
09/16/2025
Neurology
A man lies in bed on his back with a sleep mask on and mouth hanging open while asleep
News
Sleep Regularity Linked With Better Cognition, But Balance Patterns Best for BDNF
09/15/2025
Jolynn Tumolo
While regularity in day-to-day sleep patterns appears beneficial for cognitive function, sleep patterns that are rigid or highly regular may not be optimal in terms of serum brain-derived neurotrophic factor (BDNF).
While regularity in day-to-day sleep patterns appears beneficial for cognitive function, sleep patterns that are rigid or highly regular may not be optimal in terms of serum brain-derived neurotrophic factor (BDNF).
While regularity in day-to-day...
09/15/2025
Neurology
FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
brain scan
News
Moderate to Severe TBI Linked With Development of Malignant Brain Tumors
09/08/2025
Jolynn Tumolo
A history of moderate to severe traumatic brain injury (TBI) in US adult civilians was associated with an increased risk of developing a malignant brain tumor over follow-up.
A history of moderate to severe traumatic brain injury (TBI) in US adult civilians was associated with an increased risk of developing a malignant brain tumor over follow-up.
A history of moderate to severe...
09/08/2025
Neurology
A woman lies in bed with her mouth open snoring sleep apnea
News
New AASM Patient-Reported Outcome Tool Valid for Monitoring Sleep Apnea
09/08/2025
Jolynn Tumolo
A patient-reported outcome tool developed by the American Academy of Sleep Medicine (AASM) is clinically valid, reliable, and feasible for monitoring treatment response and longitudinal symptom progression in adults with obstructive sleep...
A patient-reported outcome tool developed by the American Academy of Sleep Medicine (AASM) is clinically valid, reliable, and feasible for monitoring treatment response and longitudinal symptom progression in adults with obstructive sleep...
A patient-reported outcome tool...
09/08/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
An illustration of a brain with a puzzle piece missing, surrounded by doctors with elderly patients
News
In Early Trial, Ambroxol Shows Promise for Parkinson Disease Dementia
09/02/2025
Jolynn Tumolo
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for...
09/02/2025
Neurology
A head in profile with cogs coming out of it against an orange background
News
Less Than a Third of Patients With Focal Epilepsy Become Seizure-Free on First ASM
08/26/2025
Jolynn Tumolo
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly diagnosed focal epilepsy require more than 1 antiseizure medication (ASM) and more than 1 year to achieve seizure freedom.
Most patients with newly...
08/26/2025
Neurology

Alzheimer's Disease CME Series

Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology

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