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Parkinson Disease Topic Center

a man lies in bed sleeping while wearing a CPAP machine
News
Untreated Sleep Apnea Nearly Doubles Parkinson Disease Risk
12/09/2025
Brionna Mendoza
Obstructive sleep apnea (OSA) appears to nearly double the risk for later development of Parkinson disease (PD), but early continuous positive airway pressure (CPAP) treatment may attenuate that risk by 30%.
Obstructive sleep apnea (OSA) appears to nearly double the risk for later development of Parkinson disease (PD), but early continuous positive airway pressure (CPAP) treatment may attenuate that risk by 30%.
Obstructive sleep apnea (OSA)...
12/09/2025
Neurology
restless legs syndrom
News
Restless Legs Syndrome Associated With Higher Risk for Parkinson Disease
11/06/2025
Brionna Mendoza
Restless legs syndrome (RLS) was found to be associated with an increased risk of developing Parkinson disease (PD).
Restless legs syndrome (RLS) was found to be associated with an increased risk of developing Parkinson disease (PD).
Restless legs syndrome (RLS) was...
11/06/2025
Neurology
deep brain stimulation
News
Personalized, Adaptive Deep Brain Stimulation Effective in Patients With PD
10/02/2025
Jolynn Tumolo
Long-term at-home adaptive deep brain stimulation (aDBS) was tolerable, effective, and safe in patients with Parkinson disease (PD) whose symptoms were previously stable with continuous deep brain stimulation (cDBS).
Long-term at-home adaptive deep brain stimulation (aDBS) was tolerable, effective, and safe in patients with Parkinson disease (PD) whose symptoms were previously stable with continuous deep brain stimulation (cDBS).
Long-term at-home adaptive deep...
10/02/2025
Neurology
An illustration of a brain with a puzzle piece missing, surrounded by doctors with elderly patients
News
In Early Trial, Ambroxol Shows Promise for Parkinson Disease Dementia
09/02/2025
Jolynn Tumolo
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for...
09/02/2025
Neurology
A set of cycling bikes at the gym
News
Long-Term Exercise Significantly Modifies Neuronal Activity in Patients With PD
08/11/2025
Jolynn Tumolo
Patients with Parkinson disease (PD) demonstrated measurable changes in brain signals associated with motor control and movement after 12 sessions of dynamic cycling over a 4-week period.
Patients with Parkinson disease (PD) demonstrated measurable changes in brain signals associated with motor control and movement after 12 sessions of dynamic cycling over a 4-week period.
Patients with Parkinson disease...
08/11/2025
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
Vyalev Contraindications
07/29/2025
Brionna Mendoza
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
07/29/2025
Neurology
behavioral therapy
News
Behavioral Therapy Noninferior to Drug Therapy in Treating Overactive Bladder Symptoms in Patients With PD
07/17/2025
Maria Mantas
Behavioral therapy is noninferior to drug therapy in improving overactive bladder (OAB) symptoms in patients with Parkinson disease (PD), according to a recent study published in JAMA Neurology.
Behavioral therapy is noninferior to drug therapy in improving overactive bladder (OAB) symptoms in patients with Parkinson disease (PD), according to a recent study published in JAMA Neurology.
Behavioral therapy is...
07/17/2025
Neurology
four people ponder a question with question marks over their head
Quiz
Dopaminergic Therapy in Early Parkinson Disease
07/10/2025
Test your guideline knowledge with this quick quiz!
Test your guideline knowledge with this quick quiz!
Test your guideline knowledge...
07/10/2025
Neurology
An illustrated picture shows two cartoon doctors, one holding up a magnifying glass to a cartoon brain.
News
α-Synuclein Seed Amplification Assay Kinetic Measures Offer Diagnostic, Prognostic Value in PD
06/30/2025
Jolynn Tumolo
Assessing cerebrospinal fluid (CSF) α-synuclein seed amplification assay measures could help differentiate Parkinson disease (PD) from progressive supranuclear palsy with Lewy body co-pathology.
Assessing cerebrospinal fluid (CSF) α-synuclein seed amplification assay measures could help differentiate Parkinson disease (PD) from progressive supranuclear palsy with Lewy body co-pathology.
Assessing cerebrospinal fluid...
06/30/2025
Neurology
an illustration of a brain and a colon
News
Cognitive Impairment in Parkinson Disease Linked to Mouth and Gut Bacteria
06/10/2025
Brionna Mendoza
A new study has identified a link between the progression of cognitive impairment in Parkinson disease and the bacteria residing in the mouth and the gut.
A new study has identified a link between the progression of cognitive impairment in Parkinson disease and the bacteria residing in the mouth and the gut.
A new study has identified a...
06/10/2025
Neurology

Migraine CME Series

News

a man lies in bed sleeping while wearing a CPAP machine
News
Untreated Sleep Apnea Nearly Doubles Parkinson Disease Risk
12/09/2025
Brionna Mendoza
Obstructive sleep apnea (OSA) appears to nearly double the risk for later development of Parkinson disease (PD), but early continuous positive airway pressure (CPAP) treatment may attenuate that risk by 30%.
Obstructive sleep apnea (OSA) appears to nearly double the risk for later development of Parkinson disease (PD), but early continuous positive airway pressure (CPAP) treatment may attenuate that risk by 30%.
Obstructive sleep apnea (OSA)...
12/09/2025
Neurology
restless legs syndrom
News
Restless Legs Syndrome Associated With Higher Risk for Parkinson Disease
11/06/2025
Brionna Mendoza
Restless legs syndrome (RLS) was found to be associated with an increased risk of developing Parkinson disease (PD).
Restless legs syndrome (RLS) was found to be associated with an increased risk of developing Parkinson disease (PD).
Restless legs syndrome (RLS) was...
11/06/2025
Neurology
deep brain stimulation
News
Personalized, Adaptive Deep Brain Stimulation Effective in Patients With PD
10/02/2025
Jolynn Tumolo
Long-term at-home adaptive deep brain stimulation (aDBS) was tolerable, effective, and safe in patients with Parkinson disease (PD) whose symptoms were previously stable with continuous deep brain stimulation (cDBS).
Long-term at-home adaptive deep brain stimulation (aDBS) was tolerable, effective, and safe in patients with Parkinson disease (PD) whose symptoms were previously stable with continuous deep brain stimulation (cDBS).
Long-term at-home adaptive deep...
10/02/2025
Neurology
An illustration of a brain with a puzzle piece missing, surrounded by doctors with elderly patients
News
In Early Trial, Ambroxol Shows Promise for Parkinson Disease Dementia
09/02/2025
Jolynn Tumolo
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for treating respiratory conditions was safe, well-tolerated, and demonstrated target engagement in patients with Parkinson disease dementia (PDD).
A drug used in Europe for...
09/02/2025
Neurology
behavioral therapy
News
Behavioral Therapy Noninferior to Drug Therapy in Treating Overactive Bladder Symptoms in Patients With PD
07/17/2025
Maria Mantas
Behavioral therapy is noninferior to drug therapy in improving overactive bladder (OAB) symptoms in patients with Parkinson disease (PD), according to a recent study published in JAMA Neurology.
Behavioral therapy is noninferior to drug therapy in improving overactive bladder (OAB) symptoms in patients with Parkinson disease (PD), according to a recent study published in JAMA Neurology.
Behavioral therapy is...
07/17/2025
Neurology
An illustrated picture shows two cartoon doctors, one holding up a magnifying glass to a cartoon brain.
News
α-Synuclein Seed Amplification Assay Kinetic Measures Offer Diagnostic, Prognostic Value in PD
06/30/2025
Jolynn Tumolo
Assessing cerebrospinal fluid (CSF) α-synuclein seed amplification assay measures could help differentiate Parkinson disease (PD) from progressive supranuclear palsy with Lewy body co-pathology.
Assessing cerebrospinal fluid (CSF) α-synuclein seed amplification assay measures could help differentiate Parkinson disease (PD) from progressive supranuclear palsy with Lewy body co-pathology.
Assessing cerebrospinal fluid...
06/30/2025
Neurology
an illustration of a brain and a colon
News
Cognitive Impairment in Parkinson Disease Linked to Mouth and Gut Bacteria
06/10/2025
Brionna Mendoza
A new study has identified a link between the progression of cognitive impairment in Parkinson disease and the bacteria residing in the mouth and the gut.
A new study has identified a link between the progression of cognitive impairment in Parkinson disease and the bacteria residing in the mouth and the gut.
A new study has identified a...
06/10/2025
Neurology
Neurons in the brain
News
Risk Factors for Late-Onset Epilepsy in Patients With Cognitive Decline Identified
04/21/2025
Jolynn Tumolo
Late-onset epilepsy (LOE) risk factors in people with cognitive decline include Parkinson disease, early-onset dementia (before age 60), poor cognition, stroke or transient ischemic attacks, Alzheimer disease, and the APOE4 allele.
Late-onset epilepsy (LOE) risk factors in people with cognitive decline include Parkinson disease, early-onset dementia (before age 60), poor cognition, stroke or transient ischemic attacks, Alzheimer disease, and the APOE4 allele.
Late-onset epilepsy (LOE) risk...
04/21/2025
Neurology
An illustration of a brain against a blue background, with a deep brain stimulation device connected via electrodes
News
FDA Approves ‘Self-Adjusting’ DBS Therapy for Parkinson Disease
02/25/2025
Brionna Mendoza
On Monday, the United States Food and Drug Administration (FDA) approved an adaptive deep brain stimulation (aDBS) technology for people living with Parkinson disease (PD).
On Monday, the United States Food and Drug Administration (FDA) approved an adaptive deep brain stimulation (aDBS) technology for people living with Parkinson disease (PD).
On Monday, the United States...
02/25/2025
Neurology
fda building sign
News
FDA Approves Apomorphine Drug-Device for Movement Symptoms in Parkinson Disease
02/04/2025
Brionna Mendoza
The US Food and Drug Administration (FDA) approved a drug-device combination to treat movement-related symptoms in advanced Parkinson disease.
The US Food and Drug Administration (FDA) approved a drug-device combination to treat movement-related symptoms in advanced Parkinson disease.
The US Food and Drug...
02/04/2025
Neurology
An orange prescription container with generic pills spilling out in front of it
News
Antidepressant Use Not Linked to Worse Traumatic Brain Injury Outcomes
02/03/2026
Brionna Mendoza
A large nationwide cohort study found no evidence that preinjury antidepressant use increases short-term mortality, need for emergency brain surgery, or length of hospitalization following TBI.
A large nationwide cohort study found no evidence that preinjury antidepressant use increases short-term mortality, need for emergency brain surgery, or length of hospitalization following TBI.
A large nationwide cohort study...
02/03/2026
Psych Congress Network
a mother and daughter sit at a table
News
Fremanezumab Reduces Migraine Days in Pediatric Episodic Migraine
01/30/2026
Maria Mantas
In a recent randomized, placebo-controlled trial, researchers found that fremanezumab significantly reduced monthly migraine days compared with placebo in children and adolescents with episodic migraine. 
In a recent randomized, placebo-controlled trial, researchers found that fremanezumab significantly reduced monthly migraine days compared with placebo in children and adolescents with episodic migraine. 
In a recent randomized,...
01/30/2026
Neurology
fda building sign
News
FDA Approves Copper Histidinate Treatment for Pediatric Menkes Disease
01/19/2026
Brionna Mendoza
The US Food and Drug Administration (FDA) approved a copper histidinate (Zycubo) injection as the first treatment for Menkes disease in pediatric patients.
The US Food and Drug Administration (FDA) approved a copper histidinate (Zycubo) injection as the first treatment for Menkes disease in pediatric patients.
The US Food and Drug...
01/19/2026
Neurology
brain scans
News
Endovascular Thrombectomy Shows Durable 3-Year Benefit in Basilar Artery Occlusion
01/06/2026
Maria Mantas
Endovascular thrombectomy (EVT) provides durable functional and survival benefits for patients with acute basilar artery occlusion, according to long-term follow-up data from a randomized clinical trial. 
Endovascular thrombectomy (EVT) provides durable functional and survival benefits for patients with acute basilar artery occlusion, according to long-term follow-up data from a randomized clinical trial. 
Endovascular thrombectomy (EVT)...
01/06/2026
Neurology
A doctor prescribing medication for a pregnant woman
News
Antiseizure Medication Dose Adjustments During Pregnancy: Findings from the MONEAD Study
01/06/2026
Sarah Fleming
A new analysis from the US-based Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study, published in Neurology, examines how antiseizure medications (ASMs) were adjusted during pregnancy and early postpartum...
A new analysis from the US-based Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study, published in Neurology, examines how antiseizure medications (ASMs) were adjusted during pregnancy and early postpartum...
A new analysis from the US-based...
01/06/2026
Neurology
A doctor fills out a form while meeting with a patient
News
AAN Issues Evidence-Based Guideline for Management of Functional Seizures
12/18/2025
Sarah Fleming
A new clinical practice guideline from the American Academy of Neurology (AAN), published in Neurology, provides comprehensive recommendations for diagnosing and managing functional seizures.
A new clinical practice guideline from the American Academy of Neurology (AAN), published in Neurology, provides comprehensive recommendations for diagnosing and managing functional seizures.
A new clinical practice...
12/18/2025
Neurology
A doctor reviews test results with an older female patient
News
Late-Window IV Thrombolysis Before Transfer May Improve Stroke Outcomes
12/17/2025
Sarah Fleming
A multicenter study suggests that extended-window IV thrombolysis before thrombectomy transfer may enhance outcomes and recanalization in AIS-LVO without increasing hemorrhagic risk.
A multicenter study suggests that extended-window IV thrombolysis before thrombectomy transfer may enhance outcomes and recanalization in AIS-LVO without increasing hemorrhagic risk.
A multicenter study suggests...
12/17/2025
Neurology
News
Fine Particulate Air Pollution Linked to Greater Alzheimer Neuropathology, Study Finds
12/16/2025
Grace Taylor, MS, MA
Research published in JAMA Neurology links higher exposure to fine particulate air pollution (PM2.5) with more severe Alzheimer-related brain changes and faster cognitive decline in older adults.
Research published in JAMA Neurology links higher exposure to fine particulate air pollution (PM2.5) with more severe Alzheimer-related brain changes and faster cognitive decline in older adults.
Research published in JAMA...
12/16/2025
Annals of Long-Term Care
a man lies in bed sleeping while wearing a CPAP machine
News
Untreated Sleep Apnea Nearly Doubles Parkinson Disease Risk
12/09/2025
Brionna Mendoza
Obstructive sleep apnea (OSA) appears to nearly double the risk for later development of Parkinson disease (PD), but early continuous positive airway pressure (CPAP) treatment may attenuate that risk by 30%.
Obstructive sleep apnea (OSA) appears to nearly double the risk for later development of Parkinson disease (PD), but early continuous positive airway pressure (CPAP) treatment may attenuate that risk by 30%.
Obstructive sleep apnea (OSA)...
12/09/2025
Neurology
Two doctors review research data on a computer in a lab
News
Deramiocel Meets Key Endpoints in Phase 3 HOPE-3 Duchenne Trial
12/05/2025
Brionna Mendoza
Deramiocel, an investigational cell therapy for the treatment of cardiomyopathy associated with Duchenne muscular dystrophy (DMD), met its primary and secondary endpoints in the phase 3 HOPE-3 trial, according to Capricor Therapeutics.
Deramiocel, an investigational cell therapy for the treatment of cardiomyopathy associated with Duchenne muscular dystrophy (DMD), met its primary and secondary endpoints in the phase 3 HOPE-3 trial, according to Capricor Therapeutics.
Deramiocel, an investigational...
12/05/2025
Neurology

Alzheimer's Disease CME Series

Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology

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