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Alzheimer Disease Topic Center

Recent News and Updates

a bowl of fruits and vegetables indicates brain health
News
DASH Diet Linked to Lower Subjective Cognitive Decline Risk
03/02/2026
Maria Mantas
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of...
03/02/2026
Neurology
fruits, vegetables, and lean meats
Conference Coverage
Cognitive Resilience Strategies Spotlighted at ADCD Symposium
11/14/2025
Brionna Mendoza
Co-Chair Mark Agronin, MD, and James Galvin, MD, MPH, discuss connected epidemiology, lifestyle, and emerging immunotherapies to pragmatic dementia-prevention frameworks for clinical practice in Alzheimer disease treatment and prevention for...
Co-Chair Mark Agronin, MD, and James Galvin, MD, MPH, discuss connected epidemiology, lifestyle, and emerging immunotherapies to pragmatic dementia-prevention frameworks for clinical practice in Alzheimer disease treatment and prevention for...
Co-Chair Mark Agronin, MD, and...
11/14/2025
Neurology
brain
Conference Coverage
Experts Explore Neuropsychiatric Symptoms in Alzheimer Disease at Inaugural ADCD Symposium
11/13/2025
Maria Mantas
On the first day of the Alzheimer’s Disease and Cognitive Disorders (ADCD) Symposium, meeting Co-Chair Marc E. Agronin, MD, and Carolyn K. Clevenger, DNP, GNP-BC, presented on common neuropsychiatric symptoms that may impact patients with...
On the first day of the Alzheimer’s Disease and Cognitive Disorders (ADCD) Symposium, meeting Co-Chair Marc E. Agronin, MD, and Carolyn K. Clevenger, DNP, GNP-BC, presented on common neuropsychiatric symptoms that may impact patients with...
On the first day of the...
11/13/2025
Neurology
Alzheimer Disease & Cognitive Disorders Symposium
Conference Preview
First Annual ADCD Symposium to ‘Bridge the Gap’ in Alzheimer Disease Education
11/05/2025
Brionna Mendoza
Get a sneak peek into the first annual ADCD Symposium, convening November 12 to 13, 2025!
Get a sneak peek into the first annual ADCD Symposium, convening November 12 to 13, 2025!
Get a sneak peek into the first...
11/05/2025
Neurology
A man lies in bed asleep
News
Moderate to Severe OSA May Raise Risk for Cerebral Microbleeds
11/03/2025
Jolynn Tumolo
Moderate to severe obstructive sleep apnea (OSA) is independently linked with an increased risk of incident cerebral microbleeds (CMBs) over 8 years, according to a population-based study published online in JAMA Network Open.
Moderate to severe obstructive sleep apnea (OSA) is independently linked with an increased risk of incident cerebral microbleeds (CMBs) over 8 years, according to a population-based study published online in JAMA Network Open.
Moderate to severe obstructive...
11/03/2025
Neurology
a neurologist reviews a brain model with a patient
News
Posttreatment Amyloid Levels Associated With Donanemab Benefit in Early AD
10/28/2025
Jolynn Tumolo
An exploratory post hoc analysis of a randomized clinical trial that demonstrated clinical benefit with donanemab in patients with early symptomatic Alzheimer disease (AD) suggests amyloid plaque removal was the mechanism of action.
An exploratory post hoc analysis of a randomized clinical trial that demonstrated clinical benefit with donanemab in patients with early symptomatic Alzheimer disease (AD) suggests amyloid plaque removal was the mechanism of action.
An exploratory post hoc analysis...
10/28/2025
Neurology
A doctor clasps an elderly woman's hand between her own alzheimer's cognitive impairment
News
Metabolic Modulators Show Promise in Early Alzheimer Disease
10/21/2025
Jolynn Tumolo
Intranasal insulin and the diabetes drug empagliflozin were safe and demonstrated positive effects on memory, brain health, and brain blood flow in patients with mild cognitive impairment (MCI) and early Alzheimer disease (AD).
Intranasal insulin and the diabetes drug empagliflozin were safe and demonstrated positive effects on memory, brain health, and brain blood flow in patients with mild cognitive impairment (MCI) and early Alzheimer disease (AD).
Intranasal insulin and the...
10/21/2025
Neurology
US FDA sign
News
FDA Clears New Blood Test for Alzheimer Disease in Primary Care Settings
10/17/2025
Brionna Mendoza
On Monday, the US Food and Drug Administration (FDA) cleared the Elecsys pTau181 blood-based biomarker test to aid in the initial assessment for Alzheimer disease (AD) and other causes of cognitive decline, for use in primary care settings....
On Monday, the US Food and Drug Administration (FDA) cleared the Elecsys pTau181 blood-based biomarker test to aid in the initial assessment for Alzheimer disease (AD) and other causes of cognitive decline, for use in primary care settings....
On Monday, the US Food and Drug...
10/17/2025
Neurology
an illustration of a head in profile with brain against a pink background
News
Noninvasive Physiomarker Identifies MCI and AD With High Accuracy
09/16/2025
Jolynn Tumolo
A novel physiological marker that quantifies the regulation dynamics of cerebral perfusion and oxygenation surpassed the performance of cognitive assessment tests and amyloid positron emission tomography (PET) in differentiating patients with...
A novel physiological marker that quantifies the regulation dynamics of cerebral perfusion and oxygenation surpassed the performance of cognitive assessment tests and amyloid positron emission tomography (PET) in differentiating patients with...
A novel physiological marker...
09/16/2025
Neurology
FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology

Quizzes

illustration of a test
Quiz
Which factors increase the risk of late-onset epilepsy (LOE) in people with cognitive decline?
04/23/2025
Maria Mantas
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors for late-onset epilepsy (LOE) in patients with cognitive decline?
Do you remember the risk factors...
04/23/2025
Neurology
quiz
Quiz
Percentage of Patients With Major or Mild Frontotemporal NCD Found With Alzheimer Disease Pathology at Autopsy
07/11/2024
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients presenting with a syndrome suggestive of major or mild frontotemporal neurocognitive disorder (NCD) are found at autopsy to have Alzheimer disease pathology, according to the DSM-5-TR?
What percentage of patients...
07/11/2024
Psych Congress Network
Pop quiz!
Quiz
Delirium Episodes and Incident Dementia Diagnosis
04/23/2024
Put your neurology knowledge to the test with this quiz!
Put your neurology knowledge to the test with this quiz!
Put your neurology knowledge to...
04/23/2024
Neurology
Quiz
How did pet ownership affect cognitive decline in older adults?
02/09/2024
How did pets affect cognitive decline?
How did pets affect cognitive decline?
How did pets affect cognitive...
02/09/2024
Neurology
Which factors were associated with young-onset dementia risk?
Quiz
Which factors were associated with young-onset dementia risk?
01/23/2024
Did heart disease, psychedelic use, or social isolation elevate risk?
Did heart disease, psychedelic use, or social isolation elevate risk?
Did heart disease, psychedelic...
01/23/2024
Neurology
How many years of PPI use increased dementia risk?
Quiz
How many years of PPI use increased dementia risk?
09/28/2023
Pop quiz!
Pop quiz!
Pop quiz!
09/28/2023
Neurology
By how much does Alzheimer Disease increase epilepsy risk?
Quiz
Alzheimer disease increases epilepsy risk by what percent?
07/21/2023
Test your knowlege!
Test your knowlege!
Test your knowlege!
07/21/2023
Neurology
Did the MIND or Mediterranean diets affect Alzheimer Disease pathology?
Quiz
Do MIND or Mediterranean diets affect Alzheimer Disease pathology?
07/05/2023
Do you remember this study?
Do you remember this study?
Do you remember this study?
07/05/2023
Neurology
An illustrated picture shows two cartoon doctors, one holding up a magnifying glass to a cartoon brain.
Quiz
Which investigational oral agent reduces Alzheimer disease biomarkers?
03/29/2023
Test your clinical knowledge with this neurology quiz!
Test your clinical knowledge with this neurology quiz!
Test your clinical knowledge...
03/29/2023
Neurology
An illustration of a pencil marking answers on a quiz sheet.
Expert Insights Quiz
Which aspect of sleep best predicts worsening cognitive function?
02/17/2023
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge with this quick quiz!
Test your clinical knowledge...
02/17/2023
Neurology
a printed test, pencil, and clock on a desk
Quiz
Addressing Non-Response in Migraine Treatment
03/09/2026
Maria Mantas
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
03/09/2026
Neurology
Pencils spell out quiz on their erasers
Expert Insights Quiz
Outcomes Following OSA Diagnosis
01/13/2026
Brionna Mendoza
Test your knowledge of recent research with this quiz!
Test your knowledge of recent research with this quiz!
Test your knowledge of recent...
01/13/2026
Neurology
test
Quiz
Heart Attacks and Late-Onset Epilepsy Risk
12/29/2025
Maria Mantas
What was the association between myocardial infarction and late-onset epilepsy risk in older adults?
What was the association between myocardial infarction and late-onset epilepsy risk in older adults?
What was the association between...
12/29/2025
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
Delandistrogene Moxeparvovec for Duchenne Muscular Dystrophy
10/22/2025
Brionna Mendoza
Test your knowledge with this quiz!
Test your knowledge with this quiz!
Test your knowledge with this...
10/22/2025
Neurology
Pop quiz written on a blackboard with white chalk
Expert Insights Quiz
Mimics in Excessive Daytime Sleepiness
09/10/2025
Nishi Bhopal, MD
Test your knowledge with this quiz!
Test your knowledge with this quiz!
Test your knowledge with this...
09/10/2025
Neurology
quiz
Quiz
Early DOAC Initiation in AF-Related Ischemic Stroke
08/27/2025
Maria Mantas
Do you remember the details of this meta-analysis?
Do you remember the details of this meta-analysis?
Do you remember the details of...
08/27/2025
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
Vyalev Contraindications
07/29/2025
Brionna Mendoza
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
07/29/2025
Neurology
four people ponder a question with question marks over their head
Quiz
Dopaminergic Therapy in Early Parkinson Disease
07/10/2025
Test your guideline knowledge with this quick quiz!
Test your guideline knowledge with this quick quiz!
Test your guideline knowledge...
07/10/2025
Neurology
Three illustrated faces, one sad, one neutral, one happy, with a human hand picking up the happy face
Quiz
Head Positioning Before Thrombectomy
06/25/2025
Test your knowledge with this quick quiz!
Test your knowledge with this quick quiz!
Test your knowledge with this...
06/25/2025
Neurology
Pop quiz written on a blackboard with white chalk
Quiz
Epidural Steroids for Spinal Stenosis
06/12/2025
Brionna Mendoza
Test your clinical guideline knowledge with this quick quiz!
Test your clinical guideline knowledge with this quick quiz!
Test your clinical guideline...
06/12/2025
Neurology

News

a bowl of fruits and vegetables indicates brain health
News
DASH Diet Linked to Lower Subjective Cognitive Decline Risk
03/02/2026
Maria Mantas
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of...
03/02/2026
Neurology
A man lies in bed asleep
News
Moderate to Severe OSA May Raise Risk for Cerebral Microbleeds
11/03/2025
Jolynn Tumolo
Moderate to severe obstructive sleep apnea (OSA) is independently linked with an increased risk of incident cerebral microbleeds (CMBs) over 8 years, according to a population-based study published online in JAMA Network Open.
Moderate to severe obstructive sleep apnea (OSA) is independently linked with an increased risk of incident cerebral microbleeds (CMBs) over 8 years, according to a population-based study published online in JAMA Network Open.
Moderate to severe obstructive...
11/03/2025
Neurology
a neurologist reviews a brain model with a patient
News
Posttreatment Amyloid Levels Associated With Donanemab Benefit in Early AD
10/28/2025
Jolynn Tumolo
An exploratory post hoc analysis of a randomized clinical trial that demonstrated clinical benefit with donanemab in patients with early symptomatic Alzheimer disease (AD) suggests amyloid plaque removal was the mechanism of action.
An exploratory post hoc analysis of a randomized clinical trial that demonstrated clinical benefit with donanemab in patients with early symptomatic Alzheimer disease (AD) suggests amyloid plaque removal was the mechanism of action.
An exploratory post hoc analysis...
10/28/2025
Neurology
A doctor clasps an elderly woman's hand between her own alzheimer's cognitive impairment
News
Metabolic Modulators Show Promise in Early Alzheimer Disease
10/21/2025
Jolynn Tumolo
Intranasal insulin and the diabetes drug empagliflozin were safe and demonstrated positive effects on memory, brain health, and brain blood flow in patients with mild cognitive impairment (MCI) and early Alzheimer disease (AD).
Intranasal insulin and the diabetes drug empagliflozin were safe and demonstrated positive effects on memory, brain health, and brain blood flow in patients with mild cognitive impairment (MCI) and early Alzheimer disease (AD).
Intranasal insulin and the...
10/21/2025
Neurology
US FDA sign
News
FDA Clears New Blood Test for Alzheimer Disease in Primary Care Settings
10/17/2025
Brionna Mendoza
On Monday, the US Food and Drug Administration (FDA) cleared the Elecsys pTau181 blood-based biomarker test to aid in the initial assessment for Alzheimer disease (AD) and other causes of cognitive decline, for use in primary care settings....
On Monday, the US Food and Drug Administration (FDA) cleared the Elecsys pTau181 blood-based biomarker test to aid in the initial assessment for Alzheimer disease (AD) and other causes of cognitive decline, for use in primary care settings....
On Monday, the US Food and Drug...
10/17/2025
Neurology
an illustration of a head in profile with brain against a pink background
News
Noninvasive Physiomarker Identifies MCI and AD With High Accuracy
09/16/2025
Jolynn Tumolo
A novel physiological marker that quantifies the regulation dynamics of cerebral perfusion and oxygenation surpassed the performance of cognitive assessment tests and amyloid positron emission tomography (PET) in differentiating patients with...
A novel physiological marker that quantifies the regulation dynamics of cerebral perfusion and oxygenation surpassed the performance of cognitive assessment tests and amyloid positron emission tomography (PET) in differentiating patients with...
A novel physiological marker...
09/16/2025
Neurology
FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
A person completes a puzzle of a profile of a head, with a piece missing from where the brain is located.
News
Alzheimer Disease Drugs Show Double the Impact in Long-Term Extension Results
08/05/2025
Jolynn Tumolo
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer...
08/05/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Multiple Sclerosis May Increase Risk for Alzheimer Disease
07/30/2025
Brionna Mendoza
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may...
07/30/2025
Neurology
a woman holds another person's hand for support
News
Suicidality at Epilepsy Diagnosis Predicts Future Drug Resistance Risk
03/16/2026
Maria Mantas
A prospective cohort study found that suicidality at the time of focal epilepsy diagnosis was linked to a more than twofold increased risk of future antiseizure medication (ASM) treatment resistance.
A prospective cohort study found that suicidality at the time of focal epilepsy diagnosis was linked to a more than twofold increased risk of future antiseizure medication (ASM) treatment resistance.
A prospective cohort study found...
03/16/2026
Neurology
A woman lies on the couch holding an ice pack to her head
News
Migraine Nearly Doubles Depression and Anxiety Risk in Cohort Study
03/10/2026
Brionna Mendoza
Patients with migraine are at 2 times the risk for depression or anxiety compared to those without migraine, according to a large nationwide Swedish cohort study published in The Journal of Headache and Pain.
Patients with migraine are at 2 times the risk for depression or anxiety compared to those without migraine, according to a large nationwide Swedish cohort study published in The Journal of Headache and Pain.
Patients with migraine are at 2...
03/10/2026
Psych Congress Network
A nurse and a doctor review information on a computer in a lab clinical study research trial
News
Fenebrutinib for Multiple Sclerosis Returns Significant Phase III Results
03/04/2026
Brionna Mendoza
The pivotal Phase III FENhance 1 trial of fenebrutinib met its primary endpoint in relapsing multiple sclerosis (RMS), demonstrating statistically significant and clinically meaningful reductions in relapse activity.
The pivotal Phase III FENhance 1 trial of fenebrutinib met its primary endpoint in relapsing multiple sclerosis (RMS), demonstrating statistically significant and clinically meaningful reductions in relapse activity.
The pivotal Phase III FENhance 1...
03/04/2026
Neurology
a bowl of fruits and vegetables indicates brain health
News
DASH Diet Linked to Lower Subjective Cognitive Decline Risk
03/02/2026
Maria Mantas
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of...
03/02/2026
Neurology
a colorful illustration of the brain
News
Five-Year Ublituximab Efficacy Sustained in Relapsing MS Trial
02/23/2026
Maria Mantas
Ublituximab provided sustained reductions in disease activity and disability progression over 5 years in adults with relapsing multiple sclerosis (RMS), according to open-label extension study findings.
Ublituximab provided sustained reductions in disease activity and disability progression over 5 years in adults with relapsing multiple sclerosis (RMS), according to open-label extension study findings.
Ublituximab provided sustained...
02/23/2026
Neurology
a row of pill bottles on a shelf
News
Cenobamate Shows Superior Effectiveness in Drug-Resistant Focal Epilepsy
02/17/2026
Maria Mantas
A large, pooled analysis found that cenobamate outperformed brivaracetam, lacosamide, and perampanel as adjunctive therapy in adults with drug-resistant focal epilepsy.
A large, pooled analysis found that cenobamate outperformed brivaracetam, lacosamide, and perampanel as adjunctive therapy in adults with drug-resistant focal epilepsy.
A large, pooled analysis found...
02/17/2026
Neurology
Two doctors review research data on a computer in a lab
News
Intravenous Tenecteplase Improves Functional Outcomes in Extended-Window Non-LVO Stroke
02/12/2026
Brionna Mendoza
The OPTION randomized clinical trial investigated whether intravenous tenecteplase administered in an extended time window after ischemic stroke onset benefits patients with non-large vessel occlusion (non-LVO) and evidence of salvageable...
The OPTION randomized clinical trial investigated whether intravenous tenecteplase administered in an extended time window after ischemic stroke onset benefits patients with non-large vessel occlusion (non-LVO) and evidence of salvageable...
The OPTION randomized clinical...
02/12/2026
Neurology
a doctor reviews brain scans
News
Phase 2 Odatroltide Trials Show Promise for Acute Ischemic Stroke Patients
02/09/2026
Maria Mantas
Data from 2 phase 2 trials suggest that LT3001 (odatroltide), a novel dual-mechanism stroke therapy, may offer functional improvement in patients with acute ischemic stroke who cannot receive standard reperfusion treatments.
Data from 2 phase 2 trials suggest that LT3001 (odatroltide), a novel dual-mechanism stroke therapy, may offer functional improvement in patients with acute ischemic stroke who cannot receive standard reperfusion treatments.
Data from 2 phase 2 trials...
02/09/2026
Neurology
An orange prescription container with generic pills spilling out in front of it
News
Antidepressant Use Not Linked to Worse Traumatic Brain Injury Outcomes
02/03/2026
Brionna Mendoza
A large nationwide cohort study found no evidence that preinjury antidepressant use increases short-term mortality, need for emergency brain surgery, or length of hospitalization following TBI.
A large nationwide cohort study found no evidence that preinjury antidepressant use increases short-term mortality, need for emergency brain surgery, or length of hospitalization following TBI.
A large nationwide cohort study...
02/03/2026
Psych Congress Network
a mother and daughter sit at a table
News
Fremanezumab Reduces Migraine Days in Pediatric Episodic Migraine
01/30/2026
Maria Mantas
In a recent randomized, placebo-controlled trial, researchers found that fremanezumab significantly reduced monthly migraine days compared with placebo in children and adolescents with episodic migraine. 
In a recent randomized, placebo-controlled trial, researchers found that fremanezumab significantly reduced monthly migraine days compared with placebo in children and adolescents with episodic migraine. 
In a recent randomized,...
01/30/2026
Neurology

Migraine CME Series

News

a bowl of fruits and vegetables indicates brain health
News
DASH Diet Linked to Lower Subjective Cognitive Decline Risk
03/02/2026
Maria Mantas
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of...
03/02/2026
Neurology
A man lies in bed asleep
News
Moderate to Severe OSA May Raise Risk for Cerebral Microbleeds
11/03/2025
Jolynn Tumolo
Moderate to severe obstructive sleep apnea (OSA) is independently linked with an increased risk of incident cerebral microbleeds (CMBs) over 8 years, according to a population-based study published online in JAMA Network Open.
Moderate to severe obstructive sleep apnea (OSA) is independently linked with an increased risk of incident cerebral microbleeds (CMBs) over 8 years, according to a population-based study published online in JAMA Network Open.
Moderate to severe obstructive...
11/03/2025
Neurology
a neurologist reviews a brain model with a patient
News
Posttreatment Amyloid Levels Associated With Donanemab Benefit in Early AD
10/28/2025
Jolynn Tumolo
An exploratory post hoc analysis of a randomized clinical trial that demonstrated clinical benefit with donanemab in patients with early symptomatic Alzheimer disease (AD) suggests amyloid plaque removal was the mechanism of action.
An exploratory post hoc analysis of a randomized clinical trial that demonstrated clinical benefit with donanemab in patients with early symptomatic Alzheimer disease (AD) suggests amyloid plaque removal was the mechanism of action.
An exploratory post hoc analysis...
10/28/2025
Neurology
A doctor clasps an elderly woman's hand between her own alzheimer's cognitive impairment
News
Metabolic Modulators Show Promise in Early Alzheimer Disease
10/21/2025
Jolynn Tumolo
Intranasal insulin and the diabetes drug empagliflozin were safe and demonstrated positive effects on memory, brain health, and brain blood flow in patients with mild cognitive impairment (MCI) and early Alzheimer disease (AD).
Intranasal insulin and the diabetes drug empagliflozin were safe and demonstrated positive effects on memory, brain health, and brain blood flow in patients with mild cognitive impairment (MCI) and early Alzheimer disease (AD).
Intranasal insulin and the...
10/21/2025
Neurology
US FDA sign
News
FDA Clears New Blood Test for Alzheimer Disease in Primary Care Settings
10/17/2025
Brionna Mendoza
On Monday, the US Food and Drug Administration (FDA) cleared the Elecsys pTau181 blood-based biomarker test to aid in the initial assessment for Alzheimer disease (AD) and other causes of cognitive decline, for use in primary care settings....
On Monday, the US Food and Drug Administration (FDA) cleared the Elecsys pTau181 blood-based biomarker test to aid in the initial assessment for Alzheimer disease (AD) and other causes of cognitive decline, for use in primary care settings....
On Monday, the US Food and Drug...
10/17/2025
Neurology
an illustration of a head in profile with brain against a pink background
News
Noninvasive Physiomarker Identifies MCI and AD With High Accuracy
09/16/2025
Jolynn Tumolo
A novel physiological marker that quantifies the regulation dynamics of cerebral perfusion and oxygenation surpassed the performance of cognitive assessment tests and amyloid positron emission tomography (PET) in differentiating patients with...
A novel physiological marker that quantifies the regulation dynamics of cerebral perfusion and oxygenation surpassed the performance of cognitive assessment tests and amyloid positron emission tomography (PET) in differentiating patients with...
A novel physiological marker...
09/16/2025
Neurology
FDA approval stamp
News
FDA Approves Subcutaneous Injection for Maintenance Treatment of Early AD
09/11/2025
Maria Mantas
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once-weekly subcutaneous lecanemab-irmb injections (LEQEMBI IQLIK) for the maintenance treatment of early Alzheimer disease (AD).
The US Food and Drug...
09/11/2025
Neurology
Mediterranean diet
News
Mediterranean Diet May Mitigate Genetic Risk for Alzheimer Disease
09/05/2025
Brionna Mendoza
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4 gene, following a Mediterranean diet may lower the risk of developing Alzheimer disease and dementia, suggest study results published in Nature Medicine.
For those carrying the APOE4...
09/05/2025
Neurology
A person completes a puzzle of a profile of a head, with a piece missing from where the brain is located.
News
Alzheimer Disease Drugs Show Double the Impact in Long-Term Extension Results
08/05/2025
Jolynn Tumolo
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer disease (AD) treated with lecanemab and donanemab experienced a higher degree of reduced cognitive decline in clinical trial extension studies compared with 18-month results from the core trials.
Patients with early Alzheimer...
08/05/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Multiple Sclerosis May Increase Risk for Alzheimer Disease
07/30/2025
Brionna Mendoza
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may...
07/30/2025
Neurology
a woman holds another person's hand for support
News
Suicidality at Epilepsy Diagnosis Predicts Future Drug Resistance Risk
03/16/2026
Maria Mantas
A prospective cohort study found that suicidality at the time of focal epilepsy diagnosis was linked to a more than twofold increased risk of future antiseizure medication (ASM) treatment resistance.
A prospective cohort study found that suicidality at the time of focal epilepsy diagnosis was linked to a more than twofold increased risk of future antiseizure medication (ASM) treatment resistance.
A prospective cohort study found...
03/16/2026
Neurology
A woman lies on the couch holding an ice pack to her head
News
Migraine Nearly Doubles Depression and Anxiety Risk in Cohort Study
03/10/2026
Brionna Mendoza
Patients with migraine are at 2 times the risk for depression or anxiety compared to those without migraine, according to a large nationwide Swedish cohort study published in The Journal of Headache and Pain.
Patients with migraine are at 2 times the risk for depression or anxiety compared to those without migraine, according to a large nationwide Swedish cohort study published in The Journal of Headache and Pain.
Patients with migraine are at 2...
03/10/2026
Psych Congress Network
A nurse and a doctor review information on a computer in a lab clinical study research trial
News
Fenebrutinib for Multiple Sclerosis Returns Significant Phase III Results
03/04/2026
Brionna Mendoza
The pivotal Phase III FENhance 1 trial of fenebrutinib met its primary endpoint in relapsing multiple sclerosis (RMS), demonstrating statistically significant and clinically meaningful reductions in relapse activity.
The pivotal Phase III FENhance 1 trial of fenebrutinib met its primary endpoint in relapsing multiple sclerosis (RMS), demonstrating statistically significant and clinically meaningful reductions in relapse activity.
The pivotal Phase III FENhance 1...
03/04/2026
Neurology
a bowl of fruits and vegetables indicates brain health
News
DASH Diet Linked to Lower Subjective Cognitive Decline Risk
03/02/2026
Maria Mantas
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of 159,347 US adults, higher adherence to 6 healthy dietary patterns was associated with lower risk of subjective cognitive decline (SCD).
In a prospective cohort of...
03/02/2026
Neurology
a colorful illustration of the brain
News
Five-Year Ublituximab Efficacy Sustained in Relapsing MS Trial
02/23/2026
Maria Mantas
Ublituximab provided sustained reductions in disease activity and disability progression over 5 years in adults with relapsing multiple sclerosis (RMS), according to open-label extension study findings.
Ublituximab provided sustained reductions in disease activity and disability progression over 5 years in adults with relapsing multiple sclerosis (RMS), according to open-label extension study findings.
Ublituximab provided sustained...
02/23/2026
Neurology
a row of pill bottles on a shelf
News
Cenobamate Shows Superior Effectiveness in Drug-Resistant Focal Epilepsy
02/17/2026
Maria Mantas
A large, pooled analysis found that cenobamate outperformed brivaracetam, lacosamide, and perampanel as adjunctive therapy in adults with drug-resistant focal epilepsy.
A large, pooled analysis found that cenobamate outperformed brivaracetam, lacosamide, and perampanel as adjunctive therapy in adults with drug-resistant focal epilepsy.
A large, pooled analysis found...
02/17/2026
Neurology
Two doctors review research data on a computer in a lab
News
Intravenous Tenecteplase Improves Functional Outcomes in Extended-Window Non-LVO Stroke
02/12/2026
Brionna Mendoza
The OPTION randomized clinical trial investigated whether intravenous tenecteplase administered in an extended time window after ischemic stroke onset benefits patients with non-large vessel occlusion (non-LVO) and evidence of salvageable...
The OPTION randomized clinical trial investigated whether intravenous tenecteplase administered in an extended time window after ischemic stroke onset benefits patients with non-large vessel occlusion (non-LVO) and evidence of salvageable...
The OPTION randomized clinical...
02/12/2026
Neurology
a doctor reviews brain scans
News
Phase 2 Odatroltide Trials Show Promise for Acute Ischemic Stroke Patients
02/09/2026
Maria Mantas
Data from 2 phase 2 trials suggest that LT3001 (odatroltide), a novel dual-mechanism stroke therapy, may offer functional improvement in patients with acute ischemic stroke who cannot receive standard reperfusion treatments.
Data from 2 phase 2 trials suggest that LT3001 (odatroltide), a novel dual-mechanism stroke therapy, may offer functional improvement in patients with acute ischemic stroke who cannot receive standard reperfusion treatments.
Data from 2 phase 2 trials...
02/09/2026
Neurology
An orange prescription container with generic pills spilling out in front of it
News
Antidepressant Use Not Linked to Worse Traumatic Brain Injury Outcomes
02/03/2026
Brionna Mendoza
A large nationwide cohort study found no evidence that preinjury antidepressant use increases short-term mortality, need for emergency brain surgery, or length of hospitalization following TBI.
A large nationwide cohort study found no evidence that preinjury antidepressant use increases short-term mortality, need for emergency brain surgery, or length of hospitalization following TBI.
A large nationwide cohort study...
02/03/2026
Psych Congress Network
a mother and daughter sit at a table
News
Fremanezumab Reduces Migraine Days in Pediatric Episodic Migraine
01/30/2026
Maria Mantas
In a recent randomized, placebo-controlled trial, researchers found that fremanezumab significantly reduced monthly migraine days compared with placebo in children and adolescents with episodic migraine. 
In a recent randomized, placebo-controlled trial, researchers found that fremanezumab significantly reduced monthly migraine days compared with placebo in children and adolescents with episodic migraine. 
In a recent randomized,...
01/30/2026
Neurology

Alzheimer's Disease CME Series

Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology

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