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Multiple Sclerosis Topic Center

A doctor looks at a brain scan
News
Obexelimab for Relapsing MS Meets Primary Endpoint in Phase 2 Trial
11/04/2025
Brionna Mendoza
In the Phase 2 MoonStone trial of obexelimab in relapsing multiple sclerosis (rMS), the investigational drug met the primary endpoint with a 95% relative reduction in new gadolinium (Gd)-enhacing (GdE) T1 hyperintense lesions over week 8 and...
In the Phase 2 MoonStone trial of obexelimab in relapsing multiple sclerosis (rMS), the investigational drug met the primary endpoint with a 95% relative reduction in new gadolinium (Gd)-enhacing (GdE) T1 hyperintense lesions over week 8 and...
In the Phase 2 MoonStone trial...
11/04/2025
Neurology
an older woman sits on a couch looking out the window
News
Menopause Not Associated With Disease Progression in MS
10/10/2025
Brionna Mendoza
Menopause was not found to drive disease progression in multiple sclerosis (MS) in women at midlife. Results from the longitudinal cohort study were published in JAMA Neurology.
Menopause was not found to drive disease progression in multiple sclerosis (MS) in women at midlife. Results from the longitudinal cohort study were published in JAMA Neurology.
Menopause was not found to drive...
10/10/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Multiple Sclerosis May Increase Risk for Alzheimer Disease
07/30/2025
Brionna Mendoza
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may...
07/30/2025
Neurology
A teddy bear against a blue background wearing a mask and stethoscope.
News
In Pediatric Onset Multiple Sclerosis, Biological Aging May Be Accelerated
06/11/2025
Brionna Mendoza
A new study suggests that biological aging may be accelerated in children living with multiple sclerosis (MS).
A new study suggests that biological aging may be accelerated in children living with multiple sclerosis (MS).
A new study suggests that...
06/11/2025
Neurology
illustration of the brain in white lines against a black background
News
Biomarker Combo Predicts MS in Patients With Radiologically Isolated Syndrome
06/09/2025
Jolynn Tumolo
Researchers have identified a combination of factors that confers a 58.3% risk of the development of multiple sclerosis (MS) over 5 years in people with radiologically isolated syndrome (pwRIS).
Researchers have identified a combination of factors that confers a 58.3% risk of the development of multiple sclerosis (MS) over 5 years in people with radiologically isolated syndrome (pwRIS).
Researchers have identified a...
06/09/2025
Neurology
a human hand holds a Vitamin D supplement pill against a background of clouds in the sky on a sunny day
News
High-Dose Vitamin D Eases Disease Activity in Patients With Multiple Sclerosis
03/20/2025
Jolynn Tumolo
High-dose vitamin D reduced disease activity over 24 months in patients with clinically isolated syndrome typical for multiple sclerosis (MS) and early relapsing-remitting MS, according to study results published in JAMA.
High-dose vitamin D reduced disease activity over 24 months in patients with clinically isolated syndrome typical for multiple sclerosis (MS) and early relapsing-remitting MS, according to study results published in JAMA.
High-dose vitamin D reduced...
03/20/2025
Neurology
News
Long COVID Symptoms Persist in Individuals With Multiple Sclerosis, Study Finds
02/10/2025
Lisa Kuhns, PhD, MD
Individuals with multiple sclerosis (MS) experience an ongoing impact of post-COVID-19 symptoms, revealing a significant overlap between post-acute sequelae of SARS-CoV-2 infection (PASC) and MS-related symptoms.
Individuals with multiple sclerosis (MS) experience an ongoing impact of post-COVID-19 symptoms, revealing a significant overlap between post-acute sequelae of SARS-CoV-2 infection (PASC) and MS-related symptoms.
Individuals with multiple...
02/10/2025
First Report Managed Care
Injectable Medication
News
MS Drug Associated with Rare Cases of Anaphylaxis, FDA Warns
02/06/2025
Jolynn Tumolo
The U.S. FDA is warning of rare, life-threatening allergic reactions associated with the injectable MS drug glatiramer acetate. Since its approval in 1996, 82 patients worldwide have required emergency care or hospitalization for anaphylaxis...
The U.S. FDA is warning of rare, life-threatening allergic reactions associated with the injectable MS drug glatiramer acetate. Since its approval in 1996, 82 patients worldwide have required emergency care or hospitalization for anaphylaxis...
The U.S. FDA is warning of rare,...
02/06/2025
Neurology
Alone or Together, CBT and Modafinil Improve MS-Related Fatigue
News
Alone or Together, CBT and Modafinil Improve MS-Related Fatigue
11/01/2024
Jolynn Tumolo
The wake-promoting drug modafinil, CBT, and a combination of both were associated with comparable, significant improvement in fatigue at 12 weeks in patients with MS and problematic fatigue.
The wake-promoting drug modafinil, CBT, and a combination of both were associated with comparable, significant improvement in fatigue at 12 weeks in patients with MS and problematic fatigue.
The wake-promoting drug...
11/01/2024
Neurology
Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS
News
Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS
10/15/2024
Jolynn Tumolo
Tolebrutinib delayed the time to onset of 6-month confirmed disability progression compared with placebo in patients with nonrelapsing secondary progressive MS, according to results presented at the European Committee for Treatment and...
Tolebrutinib delayed the time to onset of 6-month confirmed disability progression compared with placebo in patients with nonrelapsing secondary progressive MS, according to results presented at the European Committee for Treatment and...
Tolebrutinib delayed the time to...
10/15/2024
Neurology

Migraine CME Series

News

A doctor looks at a brain scan
News
Obexelimab for Relapsing MS Meets Primary Endpoint in Phase 2 Trial
11/04/2025
Brionna Mendoza
In the Phase 2 MoonStone trial of obexelimab in relapsing multiple sclerosis (rMS), the investigational drug met the primary endpoint with a 95% relative reduction in new gadolinium (Gd)-enhacing (GdE) T1 hyperintense lesions over week 8 and...
In the Phase 2 MoonStone trial of obexelimab in relapsing multiple sclerosis (rMS), the investigational drug met the primary endpoint with a 95% relative reduction in new gadolinium (Gd)-enhacing (GdE) T1 hyperintense lesions over week 8 and...
In the Phase 2 MoonStone trial...
11/04/2025
Neurology
an older woman sits on a couch looking out the window
News
Menopause Not Associated With Disease Progression in MS
10/10/2025
Brionna Mendoza
Menopause was not found to drive disease progression in multiple sclerosis (MS) in women at midlife. Results from the longitudinal cohort study were published in JAMA Neurology.
Menopause was not found to drive disease progression in multiple sclerosis (MS) in women at midlife. Results from the longitudinal cohort study were published in JAMA Neurology.
Menopause was not found to drive...
10/10/2025
Neurology
a head in profile with a heart over where the brain would be against a teal background
News
Multiple Sclerosis May Increase Risk for Alzheimer Disease
07/30/2025
Brionna Mendoza
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may increase the risk of developing Alzheimer disease (AD), according to an analysis of genetic data published in Neurodegenerative Disease Management.
Multiple sclerosis (MS) may...
07/30/2025
Neurology
A teddy bear against a blue background wearing a mask and stethoscope.
News
In Pediatric Onset Multiple Sclerosis, Biological Aging May Be Accelerated
06/11/2025
Brionna Mendoza
A new study suggests that biological aging may be accelerated in children living with multiple sclerosis (MS).
A new study suggests that biological aging may be accelerated in children living with multiple sclerosis (MS).
A new study suggests that...
06/11/2025
Neurology
illustration of the brain in white lines against a black background
News
Biomarker Combo Predicts MS in Patients With Radiologically Isolated Syndrome
06/09/2025
Jolynn Tumolo
Researchers have identified a combination of factors that confers a 58.3% risk of the development of multiple sclerosis (MS) over 5 years in people with radiologically isolated syndrome (pwRIS).
Researchers have identified a combination of factors that confers a 58.3% risk of the development of multiple sclerosis (MS) over 5 years in people with radiologically isolated syndrome (pwRIS).
Researchers have identified a...
06/09/2025
Neurology
a human hand holds a Vitamin D supplement pill against a background of clouds in the sky on a sunny day
News
High-Dose Vitamin D Eases Disease Activity in Patients With Multiple Sclerosis
03/20/2025
Jolynn Tumolo
High-dose vitamin D reduced disease activity over 24 months in patients with clinically isolated syndrome typical for multiple sclerosis (MS) and early relapsing-remitting MS, according to study results published in JAMA.
High-dose vitamin D reduced disease activity over 24 months in patients with clinically isolated syndrome typical for multiple sclerosis (MS) and early relapsing-remitting MS, according to study results published in JAMA.
High-dose vitamin D reduced...
03/20/2025
Neurology
News
Long COVID Symptoms Persist in Individuals With Multiple Sclerosis, Study Finds
02/10/2025
Lisa Kuhns, PhD, MD
Individuals with multiple sclerosis (MS) experience an ongoing impact of post-COVID-19 symptoms, revealing a significant overlap between post-acute sequelae of SARS-CoV-2 infection (PASC) and MS-related symptoms.
Individuals with multiple sclerosis (MS) experience an ongoing impact of post-COVID-19 symptoms, revealing a significant overlap between post-acute sequelae of SARS-CoV-2 infection (PASC) and MS-related symptoms.
Individuals with multiple...
02/10/2025
First Report Managed Care
Injectable Medication
News
MS Drug Associated with Rare Cases of Anaphylaxis, FDA Warns
02/06/2025
Jolynn Tumolo
The U.S. FDA is warning of rare, life-threatening allergic reactions associated with the injectable MS drug glatiramer acetate. Since its approval in 1996, 82 patients worldwide have required emergency care or hospitalization for anaphylaxis...
The U.S. FDA is warning of rare, life-threatening allergic reactions associated with the injectable MS drug glatiramer acetate. Since its approval in 1996, 82 patients worldwide have required emergency care or hospitalization for anaphylaxis...
The U.S. FDA is warning of rare,...
02/06/2025
Neurology
Alone or Together, CBT and Modafinil Improve MS-Related Fatigue
News
Alone or Together, CBT and Modafinil Improve MS-Related Fatigue
11/01/2024
Jolynn Tumolo
The wake-promoting drug modafinil, CBT, and a combination of both were associated with comparable, significant improvement in fatigue at 12 weeks in patients with MS and problematic fatigue.
The wake-promoting drug modafinil, CBT, and a combination of both were associated with comparable, significant improvement in fatigue at 12 weeks in patients with MS and problematic fatigue.
The wake-promoting drug...
11/01/2024
Neurology
Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS
News
Tolebrutinib Delays Disability Progression in Nonrelapsing Secondary Progressive MS
10/15/2024
Jolynn Tumolo
Tolebrutinib delayed the time to onset of 6-month confirmed disability progression compared with placebo in patients with nonrelapsing secondary progressive MS, according to results presented at the European Committee for Treatment and...
Tolebrutinib delayed the time to onset of 6-month confirmed disability progression compared with placebo in patients with nonrelapsing secondary progressive MS, according to results presented at the European Committee for Treatment and...
Tolebrutinib delayed the time to...
10/15/2024
Neurology
An orange prescription container with generic pills spilling out in front of it
News
Antidepressant Use Not Linked to Worse Traumatic Brain Injury Outcomes
02/03/2026
Brionna Mendoza
A large nationwide cohort study found no evidence that preinjury antidepressant use increases short-term mortality, need for emergency brain surgery, or length of hospitalization following TBI.
A large nationwide cohort study found no evidence that preinjury antidepressant use increases short-term mortality, need for emergency brain surgery, or length of hospitalization following TBI.
A large nationwide cohort study...
02/03/2026
Psych Congress Network
a mother and daughter sit at a table
News
Fremanezumab Reduces Migraine Days in Pediatric Episodic Migraine
01/30/2026
Maria Mantas
In a recent randomized, placebo-controlled trial, researchers found that fremanezumab significantly reduced monthly migraine days compared with placebo in children and adolescents with episodic migraine. 
In a recent randomized, placebo-controlled trial, researchers found that fremanezumab significantly reduced monthly migraine days compared with placebo in children and adolescents with episodic migraine. 
In a recent randomized,...
01/30/2026
Neurology
fda building sign
News
FDA Approves Copper Histidinate Treatment for Pediatric Menkes Disease
01/19/2026
Brionna Mendoza
The US Food and Drug Administration (FDA) approved a copper histidinate (Zycubo) injection as the first treatment for Menkes disease in pediatric patients.
The US Food and Drug Administration (FDA) approved a copper histidinate (Zycubo) injection as the first treatment for Menkes disease in pediatric patients.
The US Food and Drug...
01/19/2026
Neurology
brain scans
News
Endovascular Thrombectomy Shows Durable 3-Year Benefit in Basilar Artery Occlusion
01/06/2026
Maria Mantas
Endovascular thrombectomy (EVT) provides durable functional and survival benefits for patients with acute basilar artery occlusion, according to long-term follow-up data from a randomized clinical trial. 
Endovascular thrombectomy (EVT) provides durable functional and survival benefits for patients with acute basilar artery occlusion, according to long-term follow-up data from a randomized clinical trial. 
Endovascular thrombectomy (EVT)...
01/06/2026
Neurology
A doctor prescribing medication for a pregnant woman
News
Antiseizure Medication Dose Adjustments During Pregnancy: Findings from the MONEAD Study
01/06/2026
Sarah Fleming
A new analysis from the US-based Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study, published in Neurology, examines how antiseizure medications (ASMs) were adjusted during pregnancy and early postpartum...
A new analysis from the US-based Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study, published in Neurology, examines how antiseizure medications (ASMs) were adjusted during pregnancy and early postpartum...
A new analysis from the US-based...
01/06/2026
Neurology
A doctor fills out a form while meeting with a patient
News
AAN Issues Evidence-Based Guideline for Management of Functional Seizures
12/18/2025
Sarah Fleming
A new clinical practice guideline from the American Academy of Neurology (AAN), published in Neurology, provides comprehensive recommendations for diagnosing and managing functional seizures.
A new clinical practice guideline from the American Academy of Neurology (AAN), published in Neurology, provides comprehensive recommendations for diagnosing and managing functional seizures.
A new clinical practice...
12/18/2025
Neurology
A doctor reviews test results with an older female patient
News
Late-Window IV Thrombolysis Before Transfer May Improve Stroke Outcomes
12/17/2025
Sarah Fleming
A multicenter study suggests that extended-window IV thrombolysis before thrombectomy transfer may enhance outcomes and recanalization in AIS-LVO without increasing hemorrhagic risk.
A multicenter study suggests that extended-window IV thrombolysis before thrombectomy transfer may enhance outcomes and recanalization in AIS-LVO without increasing hemorrhagic risk.
A multicenter study suggests...
12/17/2025
Neurology
News
Fine Particulate Air Pollution Linked to Greater Alzheimer Neuropathology, Study Finds
12/16/2025
Grace Taylor, MS, MA
Research published in JAMA Neurology links higher exposure to fine particulate air pollution (PM2.5) with more severe Alzheimer-related brain changes and faster cognitive decline in older adults.
Research published in JAMA Neurology links higher exposure to fine particulate air pollution (PM2.5) with more severe Alzheimer-related brain changes and faster cognitive decline in older adults.
Research published in JAMA...
12/16/2025
Annals of Long-Term Care
a man lies in bed sleeping while wearing a CPAP machine
News
Untreated Sleep Apnea Nearly Doubles Parkinson Disease Risk
12/09/2025
Brionna Mendoza
Obstructive sleep apnea (OSA) appears to nearly double the risk for later development of Parkinson disease (PD), but early continuous positive airway pressure (CPAP) treatment may attenuate that risk by 30%.
Obstructive sleep apnea (OSA) appears to nearly double the risk for later development of Parkinson disease (PD), but early continuous positive airway pressure (CPAP) treatment may attenuate that risk by 30%.
Obstructive sleep apnea (OSA)...
12/09/2025
Neurology
Two doctors review research data on a computer in a lab
News
Deramiocel Meets Key Endpoints in Phase 3 HOPE-3 Duchenne Trial
12/05/2025
Brionna Mendoza
Deramiocel, an investigational cell therapy for the treatment of cardiomyopathy associated with Duchenne muscular dystrophy (DMD), met its primary and secondary endpoints in the phase 3 HOPE-3 trial, according to Capricor Therapeutics.
Deramiocel, an investigational cell therapy for the treatment of cardiomyopathy associated with Duchenne muscular dystrophy (DMD), met its primary and secondary endpoints in the phase 3 HOPE-3 trial, according to Capricor Therapeutics.
Deramiocel, an investigational...
12/05/2025
Neurology

Alzheimer's Disease CME Series

Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data
11/17/2020
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early Alzheimer Disease: Efficacy and Safety Data To view accreditation information/faculty disclosures for the program, click 
Emerging Treatments for Early...
11/17/2020
Neurology

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