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Research Summary
06/17/2026
Maria Mantas
The presence of frontal release signs (FRS), primitive reflexes that reemerge with neurodegeneration or brain injury, may help identify older adults at increased risk for future cognitive decline, according to a cohort study.
The presence of frontal release signs (FRS), primitive reflexes that reemerge with neurodegeneration or brain injury, may help identify older adults at increased risk for future cognitive decline, according to a cohort study.
The presence of frontal release...
06/17/2026
Neurology
a doctor reviews brain scans
News
06/09/2026
Maria Mantas
A multicenter randomized clinical trial found that reperfusion-guided systolic blood pressure (BP) management after successful endovascular therapy improved 90-day functional outcomes compared with guideline-recommended care.
A multicenter randomized clinical trial found that reperfusion-guided systolic blood pressure (BP) management after successful endovascular therapy improved 90-day functional outcomes compared with guideline-recommended care.
A multicenter randomized...
06/09/2026
Neurology
a strand of RNA
News
06/01/2026
Maria Mantas
SKY-0515, an investigational oral RNA splicing modifier, reduced mutant huntingtin (mHTT) protein levels in blood by up to 69% and PMS1 mRNA by up to 26% in a phase 1/2 Huntington’s disease (HD) trial. 
SKY-0515, an investigational oral RNA splicing modifier, reduced mutant huntingtin (mHTT) protein levels in blood by up to 69% and PMS1 mRNA by up to 26% in a phase 1/2 Huntington’s disease (HD) trial. 
SKY-0515, an investigational...
06/01/2026
Neurology
a man lays in bed unable to sleep
News
05/26/2026
Maria Mantas
Disruptions in sleep-wake cycles may provide scalable early markers for dementia risk in older adults, according to cohort study findings.
Disruptions in sleep-wake cycles may provide scalable early markers for dementia risk in older adults, according to cohort study findings.
Disruptions in sleep-wake cycles...
05/26/2026
Neurology
a side profile of a human head, with the top portion appearing to be made of shattered, crumpled paper
News
05/11/2026
Maria Mantas
In a South Korea–based multicenter cohort, plasma phosphorylated tau217 (p-tau217), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) were associated with cognitive decline in early-onset Alzheimer disease (EOAD). 
In a South Korea–based multicenter cohort, plasma phosphorylated tau217 (p-tau217), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) were associated with cognitive decline in early-onset Alzheimer disease (EOAD). 
In a South Korea–based...
05/11/2026
Neurology
A doctor interacts with an elderly patient
News
05/04/2026
Maria Mantas
Findings from a large Aspirin in Reducing Events in the Elderly (ASPREE) cohort suggest cognitive changes could serve as early indicators of cardiovascular risk. 
Findings from a large Aspirin in Reducing Events in the Elderly (ASPREE) cohort suggest cognitive changes could serve as early indicators of cardiovascular risk. 
Findings from a large Aspirin in...
05/04/2026
Neurology
a clinician reviews brain scans in front of a laptop
News
04/24/2026
Maria Mantas
The addition of endovascular treatment (EVT) to best medical treatment (BMT) was associated with a higher likelihood of achieving good imaging outcomes compared with BMT alone in patients with a medium or distal vessel occlusion stroke.
The addition of endovascular treatment (EVT) to best medical treatment (BMT) was associated with a higher likelihood of achieving good imaging outcomes compared with BMT alone in patients with a medium or distal vessel occlusion stroke.
The addition of endovascular...
04/24/2026
Neurology
A person holds a cannabis joint in their hands
News
04/21/2026
Brionna Mendoza
A large US longitudinal study published in Neuropsychopharmacology found that adolescents who initiated cannabis use showed flatter neurocognitive development over time than peers who did not use cannabis.
A large US longitudinal study published in Neuropsychopharmacology found that adolescents who initiated cannabis use showed flatter neurocognitive development over time than peers who did not use cannabis.
A large US longitudinal study...
04/21/2026
Psych Congress Network
a man holds his head in his hands
News
04/20/2026
Maria Mantas
Real-world data presented at the American Academy of Neurology (AAN) 2026 Annual Meeting reported improvements in migraine-related cognitive symptoms with eptinezumab (VYEPTI).
Real-world data presented at the American Academy of Neurology (AAN) 2026 Annual Meeting reported improvements in migraine-related cognitive symptoms with eptinezumab (VYEPTI).
Real-world data presented at the...
04/20/2026
Neurology
a doctor sits at a desk and takes notes while looking at a laptop
News
04/13/2026
Maria Mantas
Teleneurological ward rounds were found noninferior to conventional on-site ward rounds in subacute inpatient stroke care, according to prospective study findings.
Teleneurological ward rounds were found noninferior to conventional on-site ward rounds in subacute inpatient stroke care, according to prospective study findings.
Teleneurological ward rounds...
04/13/2026
Neurology