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Irritable Bowel Syndrome Topic Center

Featured Article

Research Highlights
01/15/2026
Rebecca Mashaw
By linking reduced beneficial bacteria and SCFAs with possible inflammatory signaling, the findings of a recent study may inform future microbiota-targeted therapies for IBS-C.
By linking reduced beneficial bacteria and SCFAs with possible inflammatory signaling, the findings of a recent study may inform future microbiota-targeted therapies for IBS-C.
By linking reduced beneficial...
01/15/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
A systematic review of over 100,000 patients confirms a higher risk of cholelithiasis and GERD with GLP-1RAs, particularly in weight-loss-focused and high-dose formulations.
A systematic review of over 100,000 patients confirms a higher risk of cholelithiasis and GERD with GLP-1RAs, particularly in weight-loss-focused and high-dose formulations.
A systematic review of over...
01/14/2026
Gastroenterology
05/08/2025
Riya Gandhi, MA
An international panel delivers the first standardized framework to evaluate and manage persistent IBS-like symptoms in patients with well-controlled IBD.
An international panel delivers the first standardized framework to evaluate and manage persistent IBS-like symptoms in patients with well-controlled IBD.
An international panel delivers...
05/08/2025
Advances in Inflammatory Bowel Disease Network
From Advances in Inflammatory Bowel Disease Network
Research Highlights
04/29/2025
Riya Gandhi, MA
An updated systematic review confirms that gut–brain neuromodulators—especially tricyclic antidepressants—can reduce global IBS symptoms and abdominal pain, though evidence for other drug classes remains limited.
An updated systematic review confirms that gut–brain neuromodulators—especially tricyclic antidepressants—can reduce global IBS symptoms and abdominal pain, though evidence for other drug classes remains limited.
An updated systematic review...
04/29/2025
Gastroenterology
News
04/29/2025
Riya Gandhi, MA
A new network meta-analysis of 28 trials finds that low FODMAP and starch- and sucrose-reduced diets outperform standard dietary advice in improving IBS symptoms, though overall evidence confidence remains limited.
A new network meta-analysis of 28 trials finds that low FODMAP and starch- and sucrose-reduced diets outperform standard dietary advice in improving IBS symptoms, though overall evidence confidence remains limited.
A new network meta-analysis of...
04/29/2025
Gastroenterology
Conference Coverage
10/28/2024
Riya Gandhi, MA
Researchers sought to determine if postmenopausal women treated with hormone replacement therapy would be at higher risk of developing irritable bowel syndrome.
Researchers sought to determine if postmenopausal women treated with hormone replacement therapy would be at higher risk of developing irritable bowel syndrome.
Researchers sought to determine...
10/28/2024
Gastroenterology
News
03/28/2024
Jolynn Tumolo
Almost half of those surveyed had not sought medical care for their IBS symptoms during the previous year.
Almost half of those surveyed had not sought medical care for their IBS symptoms during the previous year.
Almost half of those surveyed...
03/28/2024
Gastroenterology
Conference Coverage
01/02/2024
Priyam Vora
Dr Ali Rezaie explained the role of microbiome in disorders such as irritable bowel syndrome and its subtypes.
Dr Ali Rezaie explained the role of microbiome in disorders such as irritable bowel syndrome and its subtypes.
Dr Ali Rezaie explained the role...
01/02/2024
Gastroenterology
News
10/02/2023
Rebecca Mashaw
The pandemic may have influenced the results of a national survey, researchers say.
The pandemic may have influenced the results of a national survey, researchers say.
The pandemic may have influenced...
10/02/2023
Gastroenterology
News
05/10/2022
Consultation with a registered dietitian nutritionist can help patients with irritable bowel syndrome to manage their condition, according to a clinical update from the American Gastroenterological Association.
Consultation with a registered dietitian nutritionist can help patients with irritable bowel syndrome to manage their condition, according to a clinical update from the American Gastroenterological Association.
Consultation with a registered...
05/10/2022
Gastroenterology
children & veggies
Quiz
04/08/2022
Which type of diet is the most "patient friendly" for nonconstipated irritable bowel syndrome? Take our quick quiz to find out!
Which type of diet is the most "patient friendly" for nonconstipated irritable bowel syndrome? Take our quick quiz to find out!
Which type of diet is the most...
04/08/2022
Gastroenterology

News

Research Highlights
04/29/2025
Riya Gandhi, MA
An updated systematic review confirms that gut–brain neuromodulators—especially tricyclic antidepressants—can reduce global IBS symptoms and abdominal pain, though evidence for other drug classes remains limited.
An updated systematic review confirms that gut–brain neuromodulators—especially tricyclic antidepressants—can reduce global IBS symptoms and abdominal pain, though evidence for other drug classes remains limited.
An updated systematic review...
04/29/2025
Gastroenterology
News
04/29/2025
Riya Gandhi, MA
A new network meta-analysis of 28 trials finds that low FODMAP and starch- and sucrose-reduced diets outperform standard dietary advice in improving IBS symptoms, though overall evidence confidence remains limited.
A new network meta-analysis of 28 trials finds that low FODMAP and starch- and sucrose-reduced diets outperform standard dietary advice in improving IBS symptoms, though overall evidence confidence remains limited.
A new network meta-analysis of...
04/29/2025
Gastroenterology
News
03/28/2024
Jolynn Tumolo
Almost half of those surveyed had not sought medical care for their IBS symptoms during the previous year.
Almost half of those surveyed had not sought medical care for their IBS symptoms during the previous year.
Almost half of those surveyed...
03/28/2024
Gastroenterology
News
10/02/2023
Rebecca Mashaw
The pandemic may have influenced the results of a national survey, researchers say.
The pandemic may have influenced the results of a national survey, researchers say.
The pandemic may have influenced...
10/02/2023
Gastroenterology
News
05/10/2022
Consultation with a registered dietitian nutritionist can help patients with irritable bowel syndrome to manage their condition, according to a clinical update from the American Gastroenterological Association.
Consultation with a registered dietitian nutritionist can help patients with irritable bowel syndrome to manage their condition, according to a clinical update from the American Gastroenterological Association.
Consultation with a registered...
05/10/2022
Gastroenterology
News
03/21/2022
Low FODMAP and gluten-free diets are also effective but less popular than traditional dietary advice among patients with nonconstipated irritable bowel syndrome, according to research.
Low FODMAP and gluten-free diets are also effective but less popular than traditional dietary advice among patients with nonconstipated irritable bowel syndrome, according to research.
Low FODMAP and gluten-free diets...
03/21/2022
Gastroenterology
News
10/23/2019
Authors of a new study sought to determine whether patients with irritable bowel syndrome could experience symptom relief with fecal microbiota transplantation from a single donor with a favorable microbiota profile. The findings were...
Authors of a new study sought to determine whether patients with irritable bowel syndrome could experience symptom relief with fecal microbiota transplantation from a single donor with a favorable microbiota profile. The findings were...
Authors of a new study sought to...
10/23/2019
Gastroenterology
News
09/24/2019
The American Gastroenterological Association’s guideline applies to the evaluation of patients who are immunocompetent and who have had “watery” diarrhea for at least 4 weeks.
The American Gastroenterological Association’s guideline applies to the evaluation of patients who are immunocompetent and who have had “watery” diarrhea for at least 4 weeks.
The American Gastroenterological...
09/24/2019
Gastroenterology
Research Review
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
Emerging Therapies
01/14/2026
Jessica Garlewicz
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
In an abstract presented at the ASTRO meeting, investigators indicated that circulating tumor DNA may predict recurrence of rectal cancer following short-course radiation therapy.
In an abstract presented at the ASTRO meeting, investigators indicated that circulating tumor DNA may predict recurrence of rectal cancer following short-course radiation therapy.
In an abstract presented at the...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
01/14/2026
Gastroenterology
Research Highlights
12/15/2025
Rebecca Mashaw
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links...
12/15/2025
Gastroenterology
Research Highlights
12/11/2025
Rebecca Mashaw
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD...
12/11/2025
Gastroenterology
Conference Coverage
11/04/2025
Jessica Garlewicz
More than one-third of patients with confirmed F4 fibrosis at baseline demonstrated regression to F3 by year 2 of treatment with resmetirom for MASH cirrhosis.
More than one-third of patients with confirmed F4 fibrosis at baseline demonstrated regression to F3 by year 2 of treatment with resmetirom for MASH cirrhosis.
More than one-third of patients...
11/04/2025
Gastroenterology
Conference Coverage
11/04/2025
Jessica Garlewicz
Tirzepatide treatment was associated with lower risks of cardiovascular-related outcomes, all-cause mortality, and all-cause hospitalizations compared to semaglutide in a large real-world study, according to an abstract presented at the ACG...
Tirzepatide treatment was associated with lower risks of cardiovascular-related outcomes, all-cause mortality, and all-cause hospitalizations compared to semaglutide in a large real-world study, according to an abstract presented at the ACG...
Tirzepatide treatment was...
11/04/2025
Gastroenterology
Conference Coverage
10/27/2025
Rebecca Mashaw
In an oral abstract presented at the ACG meeting, investigators concluded that e-cigarette use—both current and former—is independently associated with a risk of peptic ulcer disease.
In an oral abstract presented at the ACG meeting, investigators concluded that e-cigarette use—both current and former—is independently associated with a risk of peptic ulcer disease.
In an oral abstract presented at...
10/27/2025
Gastroenterology
Research Highlights
10/09/2025
Rebecca Mashaw
A recent review highlights liquid biopsy’s emerging role in diagnosis and management of biliary tract cancers.
A recent review highlights liquid biopsy’s emerging role in diagnosis and management of biliary tract cancers.
A recent review highlights...
10/09/2025
Gastroenterology

Interactive

children & veggies
Quiz
04/08/2022
Which type of diet is the most "patient friendly" for nonconstipated irritable bowel syndrome? Take our quick quiz to find out!
Which type of diet is the most "patient friendly" for nonconstipated irritable bowel syndrome? Take our quick quiz to find out!
Which type of diet is the most...
04/08/2022
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a...
08/07/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology
Quiz
07/18/2025
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated...
07/18/2025
Gastroenterology
Quiz
07/18/2025
Rebecca Mashaw
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several...
07/18/2025
Gastroenterology
Quiz
07/18/2025
Rebecca Mashaw
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of...
07/18/2025
Gastroenterology