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Colorectal Cancer Topic Center

Featured

Cancer Screening
01/14/2026
Jessica Garlewicz
The BLITZ study evaluated feasibility and test accuracy among patients undergoing screening colonoscopy in routine gastroenterology practices.
The BLITZ study evaluated feasibility and test accuracy among patients undergoing screening colonoscopy in routine gastroenterology practices.
The BLITZ study evaluated...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
The findings offer comparative effectiveness data in an area previously supported largely by mechanistic and preclinical evidence.
The findings offer comparative effectiveness data in an area previously supported largely by mechanistic and preclinical evidence.
The findings offer comparative...
01/14/2026
Gastroenterology
Emerging Therapies
01/14/2026
Jessica Garlewicz
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
Nearly half of patients who received an abnormal result from a blood-based colorectal cancer screening test underwent colonoscopy within 6 months, offering early real-world insight into adoption and adherence.
Nearly half of patients who received an abnormal result from a blood-based colorectal cancer screening test underwent colonoscopy within 6 months, offering early real-world insight into adoption and adherence.
Nearly half of patients who...
01/14/2026
Gastroenterology
Research Highlights
09/05/2025
Rebecca Mashaw
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the...
09/05/2025
Gastroenterology
Research Highlights
09/05/2025
Rebecca Mashaw
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
09/05/2025
Gastroenterology
News
08/26/2025
Rebecca Mashaw
Long-term aspirin use shows promise in reducing colorectal cancer risk in certain patient populations, but optimal dosing and patient selection remain critical challenges.
Long-term aspirin use shows promise in reducing colorectal cancer risk in certain patient populations, but optimal dosing and patient selection remain critical challenges.
Long-term aspirin use shows...
08/26/2025
Gastroenterology
News
08/12/2025
Rebecca Mashaw
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in...
08/12/2025
Gastroenterology
News
08/08/2025
Riya Gandhi, MA
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in...
08/08/2025
Gastroenterology
News
08/08/2025
Riya Gandhi, MA
A large-scale study found nearly 70% of younger adults followed through with a multi-target stool DNA test for colorectal cancer screening, with digital communication playing a key role in boosting adherence.
A large-scale study found nearly 70% of younger adults followed through with a multi-target stool DNA test for colorectal cancer screening, with digital communication playing a key role in boosting adherence.
A large-scale study found nearly...
08/08/2025
Gastroenterology

News

Emerging Therapies
01/14/2026
Jessica Garlewicz
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
01/14/2026
Gastroenterology
Research Highlights
09/05/2025
Rebecca Mashaw
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the...
09/05/2025
Gastroenterology
Research Highlights
09/05/2025
Rebecca Mashaw
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
09/05/2025
Gastroenterology
News
08/12/2025
Rebecca Mashaw
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in...
08/12/2025
Gastroenterology
News
08/08/2025
Riya Gandhi, MA
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in...
08/08/2025
Gastroenterology
News
08/08/2025
Riya Gandhi, MA
A large-scale study found nearly 70% of younger adults followed through with a multi-target stool DNA test for colorectal cancer screening, with digital communication playing a key role in boosting adherence.
A large-scale study found nearly 70% of younger adults followed through with a multi-target stool DNA test for colorectal cancer screening, with digital communication playing a key role in boosting adherence.
A large-scale study found nearly...
08/08/2025
Gastroenterology
News
07/29/2025
Jessica Garlewicz
Further studies are warranted to explore the underlying mechanisms and to refine screening strategies based on individualized risk.
Further studies are warranted to explore the underlying mechanisms and to refine screening strategies based on individualized risk.
Further studies are warranted to...
07/29/2025
Gastroenterology
News
07/22/2025
Rebecca Mashaw
Sexual dysfunction and reproductive health in women with colorectal cancer call for proactive assessment and supportive interventions.
Sexual dysfunction and reproductive health in women with colorectal cancer call for proactive assessment and supportive interventions.
Sexual dysfunction and...
07/22/2025
Gastroenterology
News
07/16/2025
Rebecca Mashaw
The MOCCAS study found that stool-based postpolypectomy surveillance strategies—particularly fecal immunochemical tests—can be safe and cost-effective.
The MOCCAS study found that stool-based postpolypectomy surveillance strategies—particularly fecal immunochemical tests—can be safe and cost-effective.
The MOCCAS study found that...
07/16/2025
Gastroenterology
Research Review
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
Emerging Therapies
01/14/2026
Jessica Garlewicz
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
In an abstract presented at the ASTRO meeting, investigators indicated that circulating tumor DNA may predict recurrence of rectal cancer following short-course radiation therapy.
In an abstract presented at the ASTRO meeting, investigators indicated that circulating tumor DNA may predict recurrence of rectal cancer following short-course radiation therapy.
In an abstract presented at the...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
01/14/2026
Gastroenterology
Research Highlights
12/15/2025
Rebecca Mashaw
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links temporal changes in metabolic-associated steatotic liver disease status to markedly different risks for type 2 diabetes, cardiovascular events, and mortality.
A major cohort study links...
12/15/2025
Gastroenterology
Research Highlights
12/11/2025
Rebecca Mashaw
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD disproportionately affects women, with key risks linked to PCOS, menopause, and pregnancy.
A new review details how MASLD...
12/11/2025
Gastroenterology
Conference Coverage
11/04/2025
Jessica Garlewicz
More than one-third of patients with confirmed F4 fibrosis at baseline demonstrated regression to F3 by year 2 of treatment with resmetirom for MASH cirrhosis.
More than one-third of patients with confirmed F4 fibrosis at baseline demonstrated regression to F3 by year 2 of treatment with resmetirom for MASH cirrhosis.
More than one-third of patients...
11/04/2025
Gastroenterology
Conference Coverage
11/04/2025
Jessica Garlewicz
Tirzepatide treatment was associated with lower risks of cardiovascular-related outcomes, all-cause mortality, and all-cause hospitalizations compared to semaglutide in a large real-world study, according to an abstract presented at the ACG...
Tirzepatide treatment was associated with lower risks of cardiovascular-related outcomes, all-cause mortality, and all-cause hospitalizations compared to semaglutide in a large real-world study, according to an abstract presented at the ACG...
Tirzepatide treatment was...
11/04/2025
Gastroenterology
Conference Coverage
10/27/2025
Rebecca Mashaw
In an oral abstract presented at the ACG meeting, investigators concluded that e-cigarette use—both current and former—is independently associated with a risk of peptic ulcer disease.
In an oral abstract presented at the ACG meeting, investigators concluded that e-cigarette use—both current and former—is independently associated with a risk of peptic ulcer disease.
In an oral abstract presented at...
10/27/2025
Gastroenterology
Research Highlights
10/09/2025
Rebecca Mashaw
A recent review highlights liquid biopsy’s emerging role in diagnosis and management of biliary tract cancers.
A recent review highlights liquid biopsy’s emerging role in diagnosis and management of biliary tract cancers.
A recent review highlights...
10/09/2025
Gastroenterology

Quiz

Quiz
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
07/18/2025
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated...
07/18/2025
Gastroenterology
Quiz
07/16/2025
Riya Gandhi, MA
Which factors truly drive adherence to noninvasive CRC screening? Test your knowledge in this quick quiz.
Which factors truly drive adherence to noninvasive CRC screening? Test your knowledge in this quick quiz.
Which factors truly drive...
07/16/2025
Gastroenterology
Quiz
07/15/2025
Riya Gandhi, MA
Are you up to date on the rationale for younger screening initiation? Take this quiz to explore the epidemiologic trends that influenced new CRC guidelines.
Are you up to date on the rationale for younger screening initiation? Take this quiz to explore the epidemiologic trends that influenced new CRC guidelines.
Are you up to date on the...
07/15/2025
Gastroenterology
Quiz
05/22/2025
Rebecca Mashaw
Do you know the dietary factors contributed the most to deaths from colorectal cancer in the G20 nations during 2021? Our quick quiz will answer that question!
Do you know the dietary factors contributed the most to deaths from colorectal cancer in the G20 nations during 2021? Our quick quiz will answer that question!
Do you know the dietary factors...
05/22/2025
Gastroenterology
Quiz
12/06/2024
Rebecca Mashaw
What dietary factors contributed most to deaths from colorectal cancer? Take our quiz to find out!
What dietary factors contributed most to deaths from colorectal cancer? Take our quiz to find out!
What dietary factors contributed...
12/06/2024
Gastroenterology
Quiz
12/03/2024
Riya Gandhi, MA
Which of the following screening guidelines are recommended for patients with a familial history of colorectal cancer? Take our quiz to find out.
Which of the following screening guidelines are recommended for patients with a familial history of colorectal cancer? Take our quiz to find out.
Which of the following screening...
12/03/2024
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a...
08/07/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology
Quiz
07/18/2025
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated...
07/18/2025
Gastroenterology
Quiz
07/18/2025
Rebecca Mashaw
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several...
07/18/2025
Gastroenterology
Quiz
07/18/2025
Rebecca Mashaw
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of...
07/18/2025
Gastroenterology