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Colorectal Cancer Topic Center

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Research Review
02/17/2026
Jessica Garlewicz
Recent findings provide insight into adherence patterns and support continued participation in repeated FIT screening.
Recent findings provide insight into adherence patterns and support continued participation in repeated FIT screening.
Recent findings provide insight...
02/17/2026
Gastroenterology
News
02/11/2026
Jessica Garlewicz
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key...
02/11/2026
Gastroenterology
Cancer Screening
01/14/2026
Jessica Garlewicz
The BLITZ study evaluated feasibility and test accuracy among patients undergoing screening colonoscopy in routine gastroenterology practices.
The BLITZ study evaluated feasibility and test accuracy among patients undergoing screening colonoscopy in routine gastroenterology practices.
The BLITZ study evaluated...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
The findings offer comparative effectiveness data in an area previously supported largely by mechanistic and preclinical evidence.
The findings offer comparative effectiveness data in an area previously supported largely by mechanistic and preclinical evidence.
The findings offer comparative...
01/14/2026
Gastroenterology
Emerging Therapies
01/14/2026
Jessica Garlewicz
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
Nearly half of patients who received an abnormal result from a blood-based colorectal cancer screening test underwent colonoscopy within 6 months, offering early real-world insight into adoption and adherence.
Nearly half of patients who received an abnormal result from a blood-based colorectal cancer screening test underwent colonoscopy within 6 months, offering early real-world insight into adoption and adherence.
Nearly half of patients who...
01/14/2026
Gastroenterology
Research Highlights
09/05/2025
Rebecca Mashaw
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the...
09/05/2025
Gastroenterology
Research Highlights
09/05/2025
Rebecca Mashaw
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
09/05/2025
Gastroenterology
News
08/26/2025
Rebecca Mashaw
Long-term aspirin use shows promise in reducing colorectal cancer risk in certain patient populations, but optimal dosing and patient selection remain critical challenges.
Long-term aspirin use shows promise in reducing colorectal cancer risk in certain patient populations, but optimal dosing and patient selection remain critical challenges.
Long-term aspirin use shows...
08/26/2025
Gastroenterology
News
08/12/2025
Rebecca Mashaw
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in...
08/12/2025
Gastroenterology
News
08/08/2025
Riya Gandhi, MA
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in...
08/08/2025
Gastroenterology

News

Research Review
02/17/2026
Jessica Garlewicz
Recent findings provide insight into adherence patterns and support continued participation in repeated FIT screening.
Recent findings provide insight into adherence patterns and support continued participation in repeated FIT screening.
Recent findings provide insight...
02/17/2026
Gastroenterology
News
02/11/2026
Jessica Garlewicz
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key...
02/11/2026
Gastroenterology
Cancer Screening
01/14/2026
Jessica Garlewicz
The BLITZ study evaluated feasibility and test accuracy among patients undergoing screening colonoscopy in routine gastroenterology practices.
The BLITZ study evaluated feasibility and test accuracy among patients undergoing screening colonoscopy in routine gastroenterology practices.
The BLITZ study evaluated...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
The findings offer comparative effectiveness data in an area previously supported largely by mechanistic and preclinical evidence.
The findings offer comparative effectiveness data in an area previously supported largely by mechanistic and preclinical evidence.
The findings offer comparative...
01/14/2026
Gastroenterology
Emerging Therapies
01/14/2026
Jessica Garlewicz
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating mCRC, EC plus FOLFIRI offers a highly active first-line strategy for patients with BRAF V600E–mutant disease and may represent a new standard of care in this setting.
For gastroenterologists treating...
01/14/2026
Gastroenterology
Research Highlights
01/14/2026
Jessica Garlewicz
Nearly half of patients who received an abnormal result from a blood-based colorectal cancer screening test underwent colonoscopy within 6 months, offering early real-world insight into adoption and adherence.
Nearly half of patients who received an abnormal result from a blood-based colorectal cancer screening test underwent colonoscopy within 6 months, offering early real-world insight into adoption and adherence.
Nearly half of patients who...
01/14/2026
Gastroenterology
Research Highlights
09/05/2025
Rebecca Mashaw
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the...
09/05/2025
Gastroenterology
Research Highlights
09/05/2025
Rebecca Mashaw
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
09/05/2025
Gastroenterology
News
08/26/2025
Rebecca Mashaw
Long-term aspirin use shows promise in reducing colorectal cancer risk in certain patient populations, but optimal dosing and patient selection remain critical challenges.
Long-term aspirin use shows promise in reducing colorectal cancer risk in certain patient populations, but optimal dosing and patient selection remain critical challenges.
Long-term aspirin use shows...
08/26/2025
Gastroenterology
News
08/12/2025
Rebecca Mashaw
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in...
08/12/2025
Gastroenterology
FDA Alert
03/20/2026
Rebecca Mashaw
The US Food and Drug Administration (FDA) on March 19 approved linerixibat for the treatment of cholestatic pruritus in adult patients with PBC. The ileal bile acid transporter (IBAT) inhibitor reduces multiple drivers of chronic itch, which...
The US Food and Drug Administration (FDA) on March 19 approved linerixibat for the treatment of cholestatic pruritus in adult patients with PBC. The ileal bile acid transporter (IBAT) inhibitor reduces multiple drivers of chronic itch, which...
The US Food and Drug...
03/20/2026
Gastroenterology
Research Highlights
03/18/2026
Jessica Garlewicz
Findings of a recent analysis suggest that serial FIB-4 monitoring may provide prognostic value beyond a single baseline measurement.
Findings of a recent analysis suggest that serial FIB-4 monitoring may provide prognostic value beyond a single baseline measurement.
Findings of a recent analysis...
03/18/2026
Gastroenterology
Research Highlights
03/18/2026
Rebecca Mashaw
Colonic microbiota dysbiosis appears central to IBS-C pathophysiology, affecting motility, inflammation, and gut-brain interactions.
Colonic microbiota dysbiosis appears central to IBS-C pathophysiology, affecting motility, inflammation, and gut-brain interactions.
Colonic microbiota dysbiosis...
03/18/2026
Gastroenterology
Identification of Fibrosis
02/17/2026
Jessica Garlewicz
A new machine learning–based calculator may improve identification of patients with metabolic dysfunction–associated steatohepatitis (MASH) who meet fibrosis thresholds for resmetirom therapy, according to results from the ALADDIN study.
A new machine learning–based calculator may improve identification of patients with metabolic dysfunction–associated steatohepatitis (MASH) who meet fibrosis thresholds for resmetirom therapy, according to results from the ALADDIN study.
A new machine learning–based...
02/17/2026
Gastroenterology
Research Review
02/17/2026
Jessica Garlewicz
The findings underscore the potential for meaningful disease regression when alcohol cessation is achieved early.
The findings underscore the potential for meaningful disease regression when alcohol cessation is achieved early.
The findings underscore the...
02/17/2026
Gastroenterology
Research Review
02/17/2026
Jessica Garlewicz
Recent findings provide insight into adherence patterns and support continued participation in repeated FIT screening.
Recent findings provide insight into adherence patterns and support continued participation in repeated FIT screening.
Recent findings provide insight...
02/17/2026
Gastroenterology
Research Review
02/13/2026
Rebecca Mashaw
Standardization in microbiome research methodologies is critical to developing microbiota-based biomarkers that can stratify patients and tailor interventions in clinical practice, researchers concluded.
Standardization in microbiome research methodologies is critical to developing microbiota-based biomarkers that can stratify patients and tailor interventions in clinical practice, researchers concluded.
Standardization in microbiome...
02/13/2026
Gastroenterology
Research Review
02/13/2026
Rebecca Mashaw
A global review found marked inconsistencies in diagnostic criteria for IBS-C and functional constipation across clinical practice guidelines, underscoring the need for harmonized, evidence-based standards to improve diagnosis and patient...
A global review found marked inconsistencies in diagnostic criteria for IBS-C and functional constipation across clinical practice guidelines, underscoring the need for harmonized, evidence-based standards to improve diagnosis and patient...
A global review found marked...
02/13/2026
Gastroenterology
News
02/11/2026
Jessica Garlewicz
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key takeaway is that cumulative alcohol exposure and long-term drinking patterns matter when assessing CRC risk.
For gastroenterologists, the key...
02/11/2026
Gastroenterology
Research Review
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology

Quiz

Quiz
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
07/18/2025
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated...
07/18/2025
Gastroenterology
Quiz
07/16/2025
Riya Gandhi, MA
Which factors truly drive adherence to noninvasive CRC screening? Test your knowledge in this quick quiz.
Which factors truly drive adherence to noninvasive CRC screening? Test your knowledge in this quick quiz.
Which factors truly drive...
07/16/2025
Gastroenterology
Quiz
07/15/2025
Riya Gandhi, MA
Are you up to date on the rationale for younger screening initiation? Take this quiz to explore the epidemiologic trends that influenced new CRC guidelines.
Are you up to date on the rationale for younger screening initiation? Take this quiz to explore the epidemiologic trends that influenced new CRC guidelines.
Are you up to date on the...
07/15/2025
Gastroenterology
Quiz
05/22/2025
Rebecca Mashaw
Do you know the dietary factors contributed the most to deaths from colorectal cancer in the G20 nations during 2021? Our quick quiz will answer that question!
Do you know the dietary factors contributed the most to deaths from colorectal cancer in the G20 nations during 2021? Our quick quiz will answer that question!
Do you know the dietary factors...
05/22/2025
Gastroenterology
Quiz
12/06/2024
Rebecca Mashaw
What dietary factors contributed most to deaths from colorectal cancer? Take our quiz to find out!
What dietary factors contributed most to deaths from colorectal cancer? Take our quiz to find out!
What dietary factors contributed...
12/06/2024
Gastroenterology
Quiz
12/03/2024
Riya Gandhi, MA
Which of the following screening guidelines are recommended for patients with a familial history of colorectal cancer? Take our quiz to find out.
Which of the following screening guidelines are recommended for patients with a familial history of colorectal cancer? Take our quiz to find out.
Which of the following screening...
12/03/2024
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a recent study of patients with GERD and persistent reflux symptoms despite PPI therapy? Take our quick quiz to find out!
What did researchers find in a...
08/07/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology
Quiz
07/18/2025
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated techniques to improve return rates for fecal immunochemical tests for colorectal cancer. Find out what worked best by taking our quick quiz!
The TEMPO trial investigated...
07/18/2025
Gastroenterology
Quiz
07/18/2025
Rebecca Mashaw
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several social determinants of health (SDOH) are associated with the prevalence of metabolic-associated steatotic liver disease. What has been identified as the most consistent associated SDOH?
Research has shown that several...
07/18/2025
Gastroenterology
Quiz
07/18/2025
Rebecca Mashaw
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of metabolic-associated steatotic liver disease (MASLD) is increasing. What will it be in the future? Take our quiz to find out.
The prevalence of...
07/18/2025
Gastroenterology