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Disorders of Gut-Brain Interaction Topic Center

Featured Article

Research Highlights
01/15/2026
Rebecca Mashaw
By linking reduced beneficial bacteria and SCFAs with possible inflammatory signaling, the findings of a recent study may inform future microbiota-targeted therapies for IBS-C.
By linking reduced beneficial bacteria and SCFAs with possible inflammatory signaling, the findings of a recent study may inform future microbiota-targeted therapies for IBS-C.
By linking reduced beneficial...
01/15/2026
Gastroenterology
News
09/18/2025
Jessica Garlewicz
For gastroenterologists, this study underscores the importance of recognizing restrictive eating patterns in DGBI and coordinating multidisciplinary management to address both GI and psychosocial factors.
For gastroenterologists, this study underscores the importance of recognizing restrictive eating patterns in DGBI and coordinating multidisciplinary management to address both GI and psychosocial factors.
For gastroenterologists, this...
09/18/2025
Gastroenterology
News
08/28/2025
Riya Gandhi, MA
One in 5 adults in the general population report avoidant/restrictive eating, with higher rates—and more severe symptom burden—among those with bowel symptoms, suggesting a need for clinical screening across diverse patient groups.
One in 5 adults in the general population report avoidant/restrictive eating, with higher rates—and more severe symptom burden—among those with bowel symptoms, suggesting a need for clinical screening across diverse patient groups.
One in 5 adults in the general...
08/28/2025
Gastroenterology
Quiz
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
News
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology
Gut Check logo
Podcast
04/18/2025
Brian E. Lacy, PhD, MD; Laurie Keefer
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian...
04/18/2025
Gastroenterology
Gut Check logo
Podcast
03/10/2025
Brian E. Lacy, PhD, MD; Dacre Knight, MD
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides...
03/10/2025
Gastroenterology
Bill Chey
Expert Insights
07/30/2024
William D. Chey, MD
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation...
07/30/2024
Gastroenterology
Gut Check logo
Podcast
05/08/2024
Douglas A. Drossman, MD
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas...
05/08/2024
Gastroenterology
doc with stethoscope
Poll
01/09/2024
In treating gastrointestinal disorders, do gastroenterologists work better alone or as part of a multidisciplinary team? Answer our poll to understand the approaches better!
In treating gastrointestinal disorders, do gastroenterologists work better alone or as part of a multidisciplinary team? Answer our poll to understand the approaches better!
In treating gastrointestinal...
01/09/2024
Gastroenterology

Insights

News
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
Gut Check logo
Podcast
04/18/2025
Brian E. Lacy, PhD, MD; Laurie Keefer
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian...
04/18/2025
Gastroenterology
Gut Check logo
Podcast
03/10/2025
Brian E. Lacy, PhD, MD; Dacre Knight, MD
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides...
03/10/2025
Gastroenterology
Bill Chey
Expert Insights
07/30/2024
William D. Chey, MD
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation...
07/30/2024
Gastroenterology
Gut Check logo
Podcast
05/08/2024
Douglas A. Drossman, MD
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas...
05/08/2024
Gastroenterology
Gut Check
Podcast
08/07/2023
William D. Chey, MD; Lin Chang
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal...
08/07/2023
Gastroenterology
gut brain interaction
News
06/02/2023
Priyam Vora
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the...
06/02/2023
Gastroenterology
Emaran Mayer, MD
Conference Coverage
06/01/2023
Priyam Vora
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut...
06/01/2023
Gastroenterology
Keefer 2021
Podcast
05/03/2023
In this podcast, Dr Keefer, from the Icahn School of Medicine at Mt Sinai in New York City, discusses how different types of behavioral therapies can help in the management of disorders of gut-brain interaction, such as irritable bowel...
In this podcast, Dr Keefer, from the Icahn School of Medicine at Mt Sinai in New York City, discusses how different types of behavioral therapies can help in the management of disorders of gut-brain interaction, such as irritable bowel...
In this podcast, Dr Keefer, from...
05/03/2023
Gastroenterology
News
09/12/2022
Recent research confirms the importance of a multidisciplinary team of health care providers in achieving optimal outcomes in follow-up care among patients with gastrointestinal disorders.
Recent research confirms the importance of a multidisciplinary team of health care providers in achieving optimal outcomes in follow-up care among patients with gastrointestinal disorders.
Recent research confirms the...
09/12/2022
Gastroenterology
Research Review
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
Medication
01/29/2026
Anthony Lembo, MD; Megan Riehl, PsyD; Brooks D. Cash, MD
Our expert panel continues as Drs Cash, Lembo, and Riehl delve into the existing medications available to treat IBS-C, from neuromodulators to secretagogues and the sodium/hydrogen exchanger (NHE3) inhibitor tenapanor.
Our expert panel continues as Drs Cash, Lembo, and Riehl delve into the existing medications available to treat IBS-C, from neuromodulators to secretagogues and the sodium/hydrogen exchanger (NHE3) inhibitor tenapanor.
Our expert panel continues as...
01/29/2026
Gastroenterology
Treatment Guidance
01/27/2026
Nezam Afdhal, MD; Meena Bansal, MD; Zobair Younossi, MD
As hepatologists Nezam Afdhal, Meena Bansal, and Zobair Younossi continue their expert roundtable, the topic turns to the management of MASLD and MASH, including the best use of two new types of drugs--resmetirom and the GLP-1 agonists.
As hepatologists Nezam Afdhal, Meena Bansal, and Zobair Younossi continue their expert roundtable, the topic turns to the management of MASLD and MASH, including the best use of two new types of drugs--resmetirom and the GLP-1 agonists.
As hepatologists Nezam Afdhal,...
01/27/2026
Gastroenterology
Expert Insights
01/27/2026
Nezam Afdhal, MD; Meena Bansal, MD; Zobair Younossi, MD
The expert panel on MASLD and MASH continues its discussion with guidance on when a patients with suspected steatotic liver disease should be referred to a hepatology specialist.
The expert panel on MASLD and MASH continues its discussion with guidance on when a patients with suspected steatotic liver disease should be referred to a hepatology specialist.
The expert panel on MASLD and...
01/27/2026
Gastroenterology
Gut Check logo
Integrative Therapy
01/25/2026
Brian E. Lacy, PhD, MD; Jami Kinnucan, MD
Dr Brian Lacy hosts Dr Jami Kinnucan to discuss the pros and cons of using cannabis to treat some symptoms of gastrointestinal diseases.
Dr Brian Lacy hosts Dr Jami Kinnucan to discuss the pros and cons of using cannabis to treat some symptoms of gastrointestinal diseases.
Dr Brian Lacy hosts Dr Jami...
01/25/2026
Gastroenterology
Patient Treatment
01/23/2026
Anthony Lembo, MD; Brooks D. Cash, MD; Megan Riehl, PsyD
In part 2 of this roundtable series, Drs Anthony Lembo, Megan Riehl, and Brooks Cash review the varieties of treatments available for irritable bowel syndrome-constipation, including diet, lifestyle modifications, and medication.
In part 2 of this roundtable series, Drs Anthony Lembo, Megan Riehl, and Brooks Cash review the varieties of treatments available for irritable bowel syndrome-constipation, including diet, lifestyle modifications, and medication.
In part 2 of this roundtable...
01/23/2026
Gastroenterology
Diagnostics
01/22/2026
Anthony Lembo, MD; Megan Riehl, PsyD; Brooks D. Cash, MD
Diagnosing irritable bowel syndrome with constipation can be challenging. In this video, Drs Anthony Lembo, Brooks Cash, and Megan Riehl discuss the importance and the tests required to make a positive diagnosis rather than a diagnosis of...
Diagnosing irritable bowel syndrome with constipation can be challenging. In this video, Drs Anthony Lembo, Brooks Cash, and Megan Riehl discuss the importance and the tests required to make a positive diagnosis rather than a diagnosis of...
Diagnosing irritable bowel...
01/22/2026
Gastroenterology
Hilary Ugras
Clinical Pearls
01/21/2026
Hilary Ugras, NP
Hilary Ugras, NP, reviews the types of medical therapies available for treating IBS-C and how to position them in treating patients.
Hilary Ugras, NP, reviews the types of medical therapies available for treating IBS-C and how to position them in treating patients.
Hilary Ugras, NP, reviews the...
01/21/2026
Gastroenterology
Expert Insights
01/19/2026
Nezam Afdhal, MD; Meena Bansal, MD; Zobair Younossi, MD
In Part 2 of this expert roundtable Drs Afdhal, Bansal, and Younossi discuss how to determine which patients need to be screened for MASLD/MASH, how to conduct screening, and which modalities are best.
In Part 2 of this expert roundtable Drs Afdhal, Bansal, and Younossi discuss how to determine which patients need to be screened for MASLD/MASH, how to conduct screening, and which modalities are best.
In Part 2 of this expert...
01/19/2026
Gastroenterology
Expert Insights
01/15/2026
Nezam Afdhal, MD; Meena Bansal, MD; Zobair Younossi, MD
In part 1 of this multipart series on MASLD and MASH, Drs Nezam Afdhal, Meena Bansal, and Zobair Younossi provide an overview of the growing prevalence of metabolic-associated steatotic liver disease (MASLD) and metabolic-associated...
In part 1 of this multipart series on MASLD and MASH, Drs Nezam Afdhal, Meena Bansal, and Zobair Younossi provide an overview of the growing prevalence of metabolic-associated steatotic liver disease (MASLD) and metabolic-associated...
In part 1 of this multipart...
01/15/2026
Gastroenterology