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Disorders of Gut-Brain Interaction Topic Center

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News
ARFID Symptoms Common in Patients With DGBI, Population Study Finds
09/18/2025
Jessica Garlewicz
For gastroenterologists, this study underscores the importance of recognizing restrictive eating patterns in DGBI and coordinating multidisciplinary management to address both GI and psychosocial factors.
For gastroenterologists, this study underscores the importance of recognizing restrictive eating patterns in DGBI and coordinating multidisciplinary management to address both GI and psychosocial factors.
For gastroenterologists, this...
09/18/2025
Gastroenterology
News
Avoidant/Restrictive Eating Prevalent in People With and Without Bowel Symptoms
08/28/2025
Riya Gandhi, MA
One in 5 adults in the general population report avoidant/restrictive eating, with higher rates—and more severe symptom burden—among those with bowel symptoms, suggesting a need for clinical screening across diverse patient groups.
One in 5 adults in the general population report avoidant/restrictive eating, with higher rates—and more severe symptom burden—among those with bowel symptoms, suggesting a need for clinical screening across diverse patient groups.
One in 5 adults in the general...
08/28/2025
Gastroenterology
Quiz
DGBIs and GERD
08/07/2025
Rebecca Mashaw
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between esophageal disorders of gut-brain interaction and refractory reflux symptoms? Test your knowledge with our quick quiz!
Is there any association between...
08/07/2025
Gastroenterology
News
Gut-Brain Disorders Show Increase in Post-Pandemic Era
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
News
Prevalence of Overlapping Esophageal DGBIs and GERD in Patients With Refractory Reflux
08/01/2025
Rebecca Mashaw
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that more than 70% of patients with proven gastroesophageal reflux disease and refractory symptoms also exhibit features of esophageal disorders of gut-brain interaction.
A prospective study reveals that...
08/01/2025
Gastroenterology
Gut Check logo
Podcast
Gut Check: Laurie Keefer, PhD, on Gut-Directed Hypnotherapy
04/18/2025
Brian E. Lacy, PhD, MD; Laurie Keefer
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian...
04/18/2025
Gastroenterology
Gut Check logo
Podcast
Gut Check: Hypermobility and Gastric Disorders with Dr Dacre Knight
03/10/2025
Brian E. Lacy, PhD, MD; Dacre Knight, MD
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides...
03/10/2025
Gastroenterology
Bill Chey
Videos
William Chey, MD, on the Role of Diet in Disorders of Gut-Brain Interaction
07/30/2024
William D. Chey, MD
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation...
07/30/2024
Gastroenterology
Gut Check logo
Podcast
Gut Check: Douglas Drossman, MD, on Treating DGBIs With Neuromodulators
05/08/2024
Douglas A. Drossman, MD
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas...
05/08/2024
Gastroenterology
doc with stethoscope
Poll
Multidisciplinary Care in GI Recovery
01/09/2024
In treating gastrointestinal disorders, do gastroenterologists work better alone or as part of a multidisciplinary team? Answer our poll to understand the approaches better!
In treating gastrointestinal disorders, do gastroenterologists work better alone or as part of a multidisciplinary team? Answer our poll to understand the approaches better!
In treating gastrointestinal...
01/09/2024
Gastroenterology
Gut Check
Podcast
AGA/ACG Guideline on Chronic Constipation
08/07/2023
William D. Chey, MD; Lin Chang
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal...
08/07/2023
Gastroenterology

Insights

News
Gut-Brain Disorders Show Increase in Post-Pandemic Era
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
Gut Check logo
Podcast
Gut Check: Laurie Keefer, PhD, on Gut-Directed Hypnotherapy
04/18/2025
Brian E. Lacy, PhD, MD; Laurie Keefer
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian Lacy to discuss brain-gut behavioral therapies, including hypnotherapy, and how they can help patients effectively cope with the chronic symptoms of digestive disorders as well as depression and anxiety.
Dr Laurie Keefer joins Dr Brian...
04/18/2025
Gastroenterology
Gut Check logo
Podcast
Gut Check: Hypermobility and Gastric Disorders with Dr Dacre Knight
03/10/2025
Brian E. Lacy, PhD, MD; Dacre Knight, MD
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides insights into hypermobility syndromes and their relationships to disorders of gut-brain interaction and gastrointestinal symptoms in the latest Gut Check, hosted by Dr Brian Lacy.
Dr Dacre Knight provides...
03/10/2025
Gastroenterology
Bill Chey
Videos
William Chey, MD, on the Role of Diet in Disorders of Gut-Brain Interaction
07/30/2024
William D. Chey, MD
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation on the role of diet in disorders of gut-brain interaction from Digestive Disease Week 2024.
Dr Chey reviews his presentation...
07/30/2024
Gastroenterology
Gut Check logo
Podcast
Gut Check: Douglas Drossman, MD, on Treating DGBIs With Neuromodulators
05/08/2024
Douglas A. Drossman, MD
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas Drossman back to Gut Check for a follow-up podcast on disorders of gut-brain interaction, to review the use of neuromodulators in treatment.
Dr Brian Lacy brings Dr Douglas...
05/08/2024
Gastroenterology
Gut Check
Podcast
AGA/ACG Guideline on Chronic Constipation
08/07/2023
William D. Chey, MD; Lin Chang
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal societies in United States—the American Gastroenterological Association and the American College of Gastroenterology—collaborated to produce guidance on pharmacological agents available for the treatment of...
The 2 leading gastrointestinal...
08/07/2023
Gastroenterology
gut brain interaction
News
Gut-Brain Interaction Disorders Result in Poorer Quality of Life
06/02/2023
Priyam Vora
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the...
06/02/2023
Gastroenterology
Emaran Mayer, MD
Conference Coverage
Emeran Mayer, MD, Talks About All Things Gut
06/01/2023
Priyam Vora
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut...
06/01/2023
Gastroenterology
Keefer 2021
Podcast
Laurie Keefer, PhD, on Brain-Gut Behavioral Therapy
05/03/2023
In this podcast, Dr Keefer, from the Icahn School of Medicine at Mt Sinai in New York City, discusses how different types of behavioral therapies can help in the management of disorders of gut-brain interaction, such as irritable bowel...
In this podcast, Dr Keefer, from the Icahn School of Medicine at Mt Sinai in New York City, discusses how different types of behavioral therapies can help in the management of disorders of gut-brain interaction, such as irritable bowel...
In this podcast, Dr Keefer, from...
05/03/2023
Gastroenterology
News
Multidisciplinary Care More Effective for Follow-Up GI Recovery
09/12/2022
Recent research confirms the importance of a multidisciplinary team of health care providers in achieving optimal outcomes in follow-up care among patients with gastrointestinal disorders.
Recent research confirms the importance of a multidisciplinary team of health care providers in achieving optimal outcomes in follow-up care among patients with gastrointestinal disorders.
Recent research confirms the...
09/12/2022
Gastroenterology
Research Highlights
Incidence of Hepatocellular Carcinoma in MASLD Patients Quantified in Large Meta-Analysis
09/15/2025
Rebecca Mashaw
Robust pooled data highlight markedly increased hepatocellular carcinoma risk among MASLD patients with advanced fibrosis.
Robust pooled data highlight markedly increased hepatocellular carcinoma risk among MASLD patients with advanced fibrosis.
Robust pooled data highlight...
09/15/2025
Gastroenterology
FDA Alert
Obeticholic Acid Withdrawn From US Market for PBC; FDA Puts Clinical Trials on Hold
09/15/2025
Rebecca Mashaw
Intercept Pharmaceuticals will voluntarily withdraw its obeticholic acid product, Ocaliva, from the US market for the treatment of primary biliary cholangitis.
Intercept Pharmaceuticals will voluntarily withdraw its obeticholic acid product, Ocaliva, from the US market for the treatment of primary biliary cholangitis.
Intercept Pharmaceuticals will...
09/15/2025
Gastroenterology
Research Highlights
Analysis Challenges NordICC Trial Conclusions on CRC Screening and Mortality
09/05/2025
Rebecca Mashaw
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the...
09/05/2025
Gastroenterology
Research Highlights
Cumulative Social Risk Linked to Poorer Survival in Stage III Colorectal Cancer
09/05/2025
Rebecca Mashaw
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
09/05/2025
Gastroenterology
Research Highlights
Fatty Pancreas Disease Linked to Elevated Risk of Pancreatic Cancer
09/04/2025
Jessica Garlewicz
The key takeaway for clinicians is the importance of recognizing fatty pancreas disease as more than an incidental imaging finding.
The key takeaway for clinicians is the importance of recognizing fatty pancreas disease as more than an incidental imaging finding.
The key takeaway for clinicians...
09/04/2025
Gastroenterology
News
Hypertension Linked to Liver Disease Progression and Adverse Outcomes in MASLD
09/04/2025
Jessica Garlewicz
Across three large prospective cohorts, hypertension was consistently associated with worse liver-related and systemic outcomes.
Across three large prospective cohorts, hypertension was consistently associated with worse liver-related and systemic outcomes.
Across three large prospective...
09/04/2025
Gastroenterology
News
GLP-1 Receptor Agonists Linked to Lower Risk of Peptic Ulcer Disease in Patients with T2DM
09/04/2025
Jessica Garlewicz
GLP-1 RAs may offer additional protection against gastrointestinal complications among patients with type 2 diabetes mellitus.
GLP-1 RAs may offer additional protection against gastrointestinal complications among patients with type 2 diabetes mellitus.
GLP-1 RAs may offer additional...
09/04/2025
Gastroenterology
Alan Bonder
Conference Coverage
Alan Bonder, MD, on New Therapies for Pruritis in Liver Disease
08/26/2025
Alan Bonder, MD
Dr Bonder recaps news from the European Association for the Study of the Liver meeting on new therapies being investigated for the relief of pruritis in patients with primary biliary cholangitis.
Dr Bonder recaps news from the European Association for the Study of the Liver meeting on new therapies being investigated for the relief of pruritis in patients with primary biliary cholangitis.
Dr Bonder recaps news from the...
08/26/2025
Gastroenterology
FDA alert
FDA Alert
FDA Approves Semaglutide for MASH With Advanced Fibrosis
08/21/2025
Rebecca Mashaw
The first pharmacologic option authorized by the agency for MASH with moderate to severe fibrosis addresses a growing public health challenge.
The first pharmacologic option authorized by the agency for MASH with moderate to severe fibrosis addresses a growing public health challenge.
The first pharmacologic option...
08/21/2025
Gastroenterology
News
Racial Disparities Persist in Colorectal Cancer Outcomes
08/12/2025
Rebecca Mashaw
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in...
08/12/2025
Gastroenterology

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Gastroenterology Newsletter

News

News
Gut-Brain Disorders Show Increase in Post-Pandemic Era
08/04/2025
Rebecca Mashaw
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey reveals a significant rise in disorders of gut-brain interaction (DGBI) after the COVID-19 pandemic, with implications for health care utilization and quality of life.
A population-based survey...
08/04/2025
Gastroenterology
gut brain interaction
News
Gut-Brain Interaction Disorders Result in Poorer Quality of Life
06/02/2023
Priyam Vora
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the impact of disorders of gut-brain interaction goes beyond just the condition, extending to the mental and physical well-being too.
New findings reveal how the...
06/02/2023
Gastroenterology
Emaran Mayer, MD
Conference Coverage
Emeran Mayer, MD, Talks About All Things Gut
06/01/2023
Priyam Vora
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut connectome translates microbial signals into health and disease, often in response to external cues such as diet and circadian disruption.
Dr Mayer explains how the gut...
06/01/2023
Gastroenterology
News
Multidisciplinary Care More Effective for Follow-Up GI Recovery
09/12/2022
Recent research confirms the importance of a multidisciplinary team of health care providers in achieving optimal outcomes in follow-up care among patients with gastrointestinal disorders.
Recent research confirms the importance of a multidisciplinary team of health care providers in achieving optimal outcomes in follow-up care among patients with gastrointestinal disorders.
Recent research confirms the...
09/12/2022
Gastroenterology
News
GWAS Data Show Shared Genetics Between Alzheimer’s and GI Tract Disorders
08/24/2022
Researchers found a positive genetic overlap and correlation between Alzheimer’s disease and a variety of gastrointestinal disorders, including irritable bowel syndrome, but not with inflammatory bowel disease.
Researchers found a positive genetic overlap and correlation between Alzheimer’s disease and a variety of gastrointestinal disorders, including irritable bowel syndrome, but not with inflammatory bowel disease.
Researchers found a positive...
08/24/2022
Gastroenterology
News
Multidisciplinary Care Yields Better Outcomes in DGBIs
01/18/2022
A 12-month trial demonstrated that patients with disorders of gut-brain interaction treated in a multidisciplinary clinic showed greater improvements over those treated with standard of care.
A 12-month trial demonstrated that patients with disorders of gut-brain interaction treated in a multidisciplinary clinic showed greater improvements over those treated with standard of care.
A 12-month trial demonstrated...
01/18/2022
Gastroenterology
News
AGA Clinical Practices Update: Pain Management in Patients With Disorders of Gut-Brain Interaction
01/03/2022
Experts suggest best practices for managing chronic gastrointestinal pain affecting patients with disorders of gut-brain interaction.
Experts suggest best practices for managing chronic gastrointestinal pain affecting patients with disorders of gut-brain interaction.
Experts suggest best practices...
01/03/2022
Gastroenterology
Conference Coverage
Impaired Vagal Regulation May Predict Pain Response to Stimulation Therapy in Pediatric Functional Abdominal Pain Disorders
10/18/2019
The authors of a new study presented at the NASPGHAN Annual Meeting and Postgraduate Course sought to determine whether a baseline VE measure could predict pain with PENFS therapy among adolescents with functional abdominal pain disorders.
The authors of a new study presented at the NASPGHAN Annual Meeting and Postgraduate Course sought to determine whether a baseline VE measure could predict pain with PENFS therapy among adolescents with functional abdominal pain disorders.
The authors of a new study...
10/18/2019
Gastroenterology
Research Highlights
Incidence of Hepatocellular Carcinoma in MASLD Patients Quantified in Large Meta-Analysis
09/15/2025
Rebecca Mashaw
Robust pooled data highlight markedly increased hepatocellular carcinoma risk among MASLD patients with advanced fibrosis.
Robust pooled data highlight markedly increased hepatocellular carcinoma risk among MASLD patients with advanced fibrosis.
Robust pooled data highlight...
09/15/2025
Gastroenterology
FDA Alert
Obeticholic Acid Withdrawn From US Market for PBC; FDA Puts Clinical Trials on Hold
09/15/2025
Rebecca Mashaw
Intercept Pharmaceuticals will voluntarily withdraw its obeticholic acid product, Ocaliva, from the US market for the treatment of primary biliary cholangitis.
Intercept Pharmaceuticals will voluntarily withdraw its obeticholic acid product, Ocaliva, from the US market for the treatment of primary biliary cholangitis.
Intercept Pharmaceuticals will...
09/15/2025
Gastroenterology
Research Highlights
Analysis Challenges NordICC Trial Conclusions on CRC Screening and Mortality
09/05/2025
Rebecca Mashaw
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the NordICC study may underestimate the mortality benefits of screening colonoscopy due to inadequate follow-up time.
The 10-year results from the...
09/05/2025
Gastroenterology
Research Highlights
Cumulative Social Risk Linked to Poorer Survival in Stage III Colorectal Cancer
09/05/2025
Rebecca Mashaw
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found that each additional social risk factor significantly increased the likelihood of cancer-specific mortality among patients with advanced colorectal cancer.
A prospective cohort study found...
09/05/2025
Gastroenterology
Research Highlights
Fatty Pancreas Disease Linked to Elevated Risk of Pancreatic Cancer
09/04/2025
Jessica Garlewicz
The key takeaway for clinicians is the importance of recognizing fatty pancreas disease as more than an incidental imaging finding.
The key takeaway for clinicians is the importance of recognizing fatty pancreas disease as more than an incidental imaging finding.
The key takeaway for clinicians...
09/04/2025
Gastroenterology
News
Hypertension Linked to Liver Disease Progression and Adverse Outcomes in MASLD
09/04/2025
Jessica Garlewicz
Across three large prospective cohorts, hypertension was consistently associated with worse liver-related and systemic outcomes.
Across three large prospective cohorts, hypertension was consistently associated with worse liver-related and systemic outcomes.
Across three large prospective...
09/04/2025
Gastroenterology
News
GLP-1 Receptor Agonists Linked to Lower Risk of Peptic Ulcer Disease in Patients with T2DM
09/04/2025
Jessica Garlewicz
GLP-1 RAs may offer additional protection against gastrointestinal complications among patients with type 2 diabetes mellitus.
GLP-1 RAs may offer additional protection against gastrointestinal complications among patients with type 2 diabetes mellitus.
GLP-1 RAs may offer additional...
09/04/2025
Gastroenterology
FDA alert
FDA Alert
FDA Approves Semaglutide for MASH With Advanced Fibrosis
08/21/2025
Rebecca Mashaw
The first pharmacologic option authorized by the agency for MASH with moderate to severe fibrosis addresses a growing public health challenge.
The first pharmacologic option authorized by the agency for MASH with moderate to severe fibrosis addresses a growing public health challenge.
The first pharmacologic option...
08/21/2025
Gastroenterology
News
Racial Disparities Persist in Colorectal Cancer Outcomes
08/12/2025
Rebecca Mashaw
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in colorectal cancer screening and treatment, systemic inequities continue to drive higher incidence and mortality rates among Black Americans compared with White individuals, according to a recent review.
Despite significant advances in...
08/12/2025
Gastroenterology
News
Over 20 Years of Colorectal Cancer Disparities Reveal Racial and Regional Gaps in US Mortality
08/08/2025
Riya Gandhi, MA
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in colorectal cancer deaths, a 20-year study finds Black men and residents of Southern and Midwestern states continue to face disproportionately high mortality rates.
Despite national declines in...
08/08/2025
Gastroenterology

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