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Crohn's Disease Topic Center

Featured Content

Research Highlights
Infliximab and Ustekinumab Show Comparable Effectiveness in Biologic-Naïve Crohn’s Disease
01/14/2026
Jessica Garlewicz
Endoscopic response, transmural remission, and transmural response rates showed no significant differences between treatment groups at either assessment window.
Endoscopic response, transmural remission, and transmural response rates showed no significant differences between treatment groups at either assessment window.
Endoscopic response, transmural...
01/14/2026
Advances in Inflammatory Bowel Disease Network
Research Highlights
Upadacitinib Improves Outcomes in Fistulizing Crohn’s Disease
09/04/2025
Rebecca Mashaw
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing...
09/04/2025
Advances in Inflammatory Bowel Disease Network
News
Validation of a Simple Ultrasound Score for Crohn’s Disease
08/28/2025
Rebecca Mashaw
A multicenter study confirms the accuracy and reliability of a simplified ultrasound score for assessing Crohn’s disease activity.
A multicenter study confirms the accuracy and reliability of a simplified ultrasound score for assessing Crohn’s disease activity.
A multicenter study confirms the...
08/28/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Real-World Effectiveness and Safety of Risankizumab in Crohn’s Disease
08/21/2025
Rebecca Mashaw
Risankizumab demonstrates sustained clinical benefit and favorable safety in Crohn’s disease, including among ustekinumab-experienced patients.
Risankizumab demonstrates sustained clinical benefit and favorable safety in Crohn’s disease, including among ustekinumab-experienced patients.
Risankizumab demonstrates...
08/21/2025
Advances in Inflammatory Bowel Disease Network
News
Terminal Ileum Resection in Crohn’s Disease Linked to Increased Colorectal Cancer Risk
07/29/2025
Jessica Garlewicz
Further studies are warranted to explore the underlying mechanisms and to refine screening strategies based on individualized risk.
Further studies are warranted to explore the underlying mechanisms and to refine screening strategies based on individualized risk.
Further studies are warranted to...
07/29/2025
Gastroenterology
From Gastroenterology
Research Highlights
Advanced Therapies Show Greater Efficacy in Colonic vs Ileal Crohn’s Disease
07/24/2025
Rebecca Mashaw
In a meta-analysis of 14 randomized clinical trials, Janus kinase inhibitors and other advanced therapies demonstrated significantly higher efficacy in colonic compared to ileal Crohn’s disease.
In a meta-analysis of 14 randomized clinical trials, Janus kinase inhibitors and other advanced therapies demonstrated significantly higher efficacy in colonic compared to ileal Crohn’s disease.
In a meta-analysis of 14...
07/24/2025
Advances in Inflammatory Bowel Disease Network
News
Guselkumab Induction and SC Maintenance Shows Efficacy and Safety in Crohn’s Disease
07/24/2025
Rebecca Mashaw
In both trials, guselkumab significantly surpassed placebo for primary composite endpoints of clinical response at week 12 followed by either clinical remission or endoscopic response at week 48.
In both trials, guselkumab significantly surpassed placebo for primary composite endpoints of clinical response at week 12 followed by either clinical remission or endoscopic response at week 48.
In both trials, guselkumab...
07/24/2025
Advances in Inflammatory Bowel Disease Network
News
Stricture-Related Resections Rising in Crohn’s Disease Despite Overall Decline in Surgical Rates
05/29/2025
Jessica Garlewicz
The study aimed to assess longitudinal trends in crohn's disease-related bowel surgeries, particularly for obstruction, following the introduction of infliximab in 1998.
The study aimed to assess longitudinal trends in crohn's disease-related bowel surgeries, particularly for obstruction, following the introduction of infliximab in 1998.
The study aimed to assess...
05/29/2025
Advances in Inflammatory Bowel Disease Network
Miguel Regueiro MD
Conference coverage
Miguel Regueiro, MD, on Updates in Treatment of Perianal Crohn's Disease
05/12/2025
Miguel D. Regueiro, MD
Dr Regueiro reviews his presentation of the Patricia and Ralph Gianella lecture from DDW 2025 on the updates to the treatment algorithm for perianal Crohn's disease.
Dr Regueiro reviews his presentation of the Patricia and Ralph Gianella lecture from DDW 2025 on the updates to the treatment algorithm for perianal Crohn's disease.
Dr Regueiro reviews his...
05/12/2025
Advances in Inflammatory Bowel Disease Network
Ed Barnes
Conference coverage
Edward Barnes, MD, on Penetrating and Stricturing Crohn's Disease
05/09/2025
Edward L. Barnes
Dr Barnes reviews the key points of his presentation from the AIBD regional meeting on managing penetrating and stricturing complications of Crohn's disease.
Dr Barnes reviews the key points of his presentation from the AIBD regional meeting on managing penetrating and stricturing complications of Crohn's disease.
Dr Barnes reviews the key points...
05/09/2025
Advances in Inflammatory Bowel Disease Network
News
MASLD Linked to Worse Clinical Outcomes in Hospitalized Crohn’s Disease Patients
04/03/2025
Jessica Garlewicz
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409...
04/03/2025
Gastroenterology
From Gastroenterology

News

Research Highlights
Upadacitinib Improves Outcomes in Fistulizing Crohn’s Disease
09/04/2025
Rebecca Mashaw
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing...
09/04/2025
Advances in Inflammatory Bowel Disease Network
News
Validation of a Simple Ultrasound Score for Crohn’s Disease
08/28/2025
Rebecca Mashaw
A multicenter study confirms the accuracy and reliability of a simplified ultrasound score for assessing Crohn’s disease activity.
A multicenter study confirms the accuracy and reliability of a simplified ultrasound score for assessing Crohn’s disease activity.
A multicenter study confirms the...
08/28/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Real-World Effectiveness and Safety of Risankizumab in Crohn’s Disease
08/21/2025
Rebecca Mashaw
Risankizumab demonstrates sustained clinical benefit and favorable safety in Crohn’s disease, including among ustekinumab-experienced patients.
Risankizumab demonstrates sustained clinical benefit and favorable safety in Crohn’s disease, including among ustekinumab-experienced patients.
Risankizumab demonstrates...
08/21/2025
Advances in Inflammatory Bowel Disease Network
News
Terminal Ileum Resection in Crohn’s Disease Linked to Increased Colorectal Cancer Risk
07/29/2025
Jessica Garlewicz
Further studies are warranted to explore the underlying mechanisms and to refine screening strategies based on individualized risk.
Further studies are warranted to explore the underlying mechanisms and to refine screening strategies based on individualized risk.
Further studies are warranted to...
07/29/2025
Gastroenterology
Research Highlights
Advanced Therapies Show Greater Efficacy in Colonic vs Ileal Crohn’s Disease
07/24/2025
Rebecca Mashaw
In a meta-analysis of 14 randomized clinical trials, Janus kinase inhibitors and other advanced therapies demonstrated significantly higher efficacy in colonic compared to ileal Crohn’s disease.
In a meta-analysis of 14 randomized clinical trials, Janus kinase inhibitors and other advanced therapies demonstrated significantly higher efficacy in colonic compared to ileal Crohn’s disease.
In a meta-analysis of 14...
07/24/2025
Advances in Inflammatory Bowel Disease Network
News
Guselkumab Induction and SC Maintenance Shows Efficacy and Safety in Crohn’s Disease
07/24/2025
Rebecca Mashaw
In both trials, guselkumab significantly surpassed placebo for primary composite endpoints of clinical response at week 12 followed by either clinical remission or endoscopic response at week 48.
In both trials, guselkumab significantly surpassed placebo for primary composite endpoints of clinical response at week 12 followed by either clinical remission or endoscopic response at week 48.
In both trials, guselkumab...
07/24/2025
Advances in Inflammatory Bowel Disease Network
News
Stricture-Related Resections Rising in Crohn’s Disease Despite Overall Decline in Surgical Rates
05/29/2025
Jessica Garlewicz
The study aimed to assess longitudinal trends in crohn's disease-related bowel surgeries, particularly for obstruction, following the introduction of infliximab in 1998.
The study aimed to assess longitudinal trends in crohn's disease-related bowel surgeries, particularly for obstruction, following the introduction of infliximab in 1998.
The study aimed to assess...
05/29/2025
Advances in Inflammatory Bowel Disease Network
News
MASLD Linked to Worse Clinical Outcomes in Hospitalized Crohn’s Disease Patients
04/03/2025
Jessica Garlewicz
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409...
04/03/2025
Gastroenterology
News
Early Response to Upadacitinib Predicts Long-Term Improvements in Crohn’s Disease
04/03/2025
Jessica Garlewicz
Patients with early response achieved higher rates of clinical remission and reductions in fatigue and impairment.
Patients with early response achieved higher rates of clinical remission and reductions in fatigue and impairment.
Patients with early response...
04/03/2025
Advances in Inflammatory Bowel Disease Network
News
VCE-Guided Treat-to-Target Strategy Reduces Flares in Crohn’s Disease Remission
04/01/2025
Jessica Garlewicz
The study highlights the utility of mucosal assessment in driving treatment optimization, even in asymptomatic patients.
The study highlights the utility of mucosal assessment in driving treatment optimization, even in asymptomatic patients.
The study highlights the utility...
04/01/2025
Advances in Inflammatory Bowel Disease Network
Research Review
New Meta-Analysis Highlights Burden of MASLD Among IBD Patients
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
News
Medicare Will Cover GLP-1s for Obesity Under Deal with Pharma
11/06/2025
Rebecca Mashaw
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said...
11/06/2025
Advances in Inflammatory Bowel Disease Network
FDA alert
FDA Alert
FDA Approves Updated Indication for Upadacitinib in IBD
10/14/2025
Rebecca Mashaw
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for...
10/14/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Concomitant Medications Do Not Alter Efficacy of Advanced Therapies in Ulcerative Colitis, Study Finds
09/18/2025
Jessica Garlewicz
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that...
09/18/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Persistent Prothrombotic State Observed in Patients With ASUC
09/04/2025
Rebecca Mashaw
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Upadacitinib Improves Outcomes in Fistulizing Crohn’s Disease
09/04/2025
Rebecca Mashaw
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Pelvic MRI Detects Subclinical Perianal Disease in Pediatric Crohn’s Disease
09/04/2025
Jessica Garlewicz
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Mirikizumab Improves Quality of Life and Work Productivity in Moderate to Severe Crohn’s Disease
09/04/2025
Jessica Garlewicz
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Risankizumab Improves Symptom Resolution and Quality of Life in Ulcerative Colitis
09/04/2025
Jessica Garlewicz
Risankizumab led to earlier and sustained improvements in individual symptoms—including abdominal pain, bowel urgency, fecal incontinence, and sleep interruption
Risankizumab led to earlier and sustained improvements in individual symptoms—including abdominal pain, bowel urgency, fecal incontinence, and sleep interruption
Risankizumab led to earlier and...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Guselkumab Demonstrates Efficacy and Safety in Moderate-to-Severe Crohn’s Disease
09/04/2025
Jessica Garlewicz
The study met all primary and multiplicity-controlled secondary endpoints, including clinical and endoscopic outcomes through 48 weeks.
The study met all primary and multiplicity-controlled secondary endpoints, including clinical and endoscopic outcomes through 48 weeks.
The study met all primary and...
09/04/2025
Advances in Inflammatory Bowel Disease Network

Interactive Features

Quiz
Risk Factors for Surgery in Crohn’s Disease
02/26/2025
Rebecca Mashaw
Estimates vary but indicate that half or more of patients with Crohn's disease will require surgery at some point in their disease course. Do you know which factors place your patients at high risk for surgery? Take our quiz to find out!
Estimates vary but indicate that half or more of patients with Crohn's disease will require surgery at some point in their disease course. Do you know which factors place your patients at high risk for surgery? Take our quiz to find out!
Estimates vary but indicate that...
02/26/2025
Advances in Inflammatory Bowel Disease Network
medical quiz
Quiz
Surgical Outcomes for Crohn's Disease vs Ulcerative Colitis
07/14/2023
Priyam Vora
Are surgical outcomes the same for patients with Crohn's disease as they are for patients with ulcerative colitis? Find out with a quick quiz.
Are surgical outcomes the same for patients with Crohn's disease as they are for patients with ulcerative colitis? Find out with a quick quiz.
Are surgical outcomes the same...
07/14/2023
Advances in Inflammatory Bowel Disease Network
doc writing notes
Quiz
SIBO and Crohn's Disease
04/28/2023
Rebecca Mashaw
Is there any link between small intestinal bacterial overgrowth and clinical relapse in patients with quiescent Crohn disease? Take the test to find out!
Is there any link between small intestinal bacterial overgrowth and clinical relapse in patients with quiescent Crohn disease? Take the test to find out!
Is there any link between small...
04/28/2023
Advances in Inflammatory Bowel Disease Network
Quiz
Terminal Ileal Resection and CRC Risk
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
Does Hormone Replacement Therapy Affect IBD?
07/18/2025
Can hormone replacement therapy help or harm disease activity among women with IBD? Our quiz will show the answer!
Can hormone replacement therapy help or harm disease activity among women with IBD? Our quiz will show the answer!
Can hormone replacement therapy...
07/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
Can Perspiration Reveal IBD Biomarkers?
07/18/2025
Can a wearable sensor help monitor disease activity in IBD--via sweat? Take our quiz to get the answer.
Can a wearable sensor help monitor disease activity in IBD--via sweat? Take our quiz to get the answer.
Can a wearable sensor help...
07/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
Making EHRs Work
07/01/2025
Rebecca Mashaw
Which of the following factors did clinicians say in a recent study is particularly important for EHR functionality in the context of IBD?
Which of the following factors did clinicians say in a recent study is particularly important for EHR functionality in the context of IBD?
Which of the following factors...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
Do EHRs Help or Hinder in IBD Care?
07/01/2025
Rebecca Mashaw
According to a recent survey of clinicians who care for patients with inflammatory bowel disease, what percentage reported that their EHR system does not enhance patient care in IBD?
According to a recent survey of clinicians who care for patients with inflammatory bowel disease, what percentage reported that their EHR system does not enhance patient care in IBD?
According to a recent survey of...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
Advanced Combination Treatment for Refractory IBD
07/01/2025
Rebecca Mashaw
A multicenter Canadian study to evaluate advanced combination treatment (ACT) in patients with refractory inflammatory bowel disease (IBD) arrived at which of the following conclusions?
A multicenter Canadian study to evaluate advanced combination treatment (ACT) in patients with refractory inflammatory bowel disease (IBD) arrived at which of the following conclusions?
A multicenter Canadian study to...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
Hormone Replacement Impact on IBD
05/22/2025
Rebecca Mashaw
Does hormone replacement therapy have any effect on treatment for IBD among postmenopausal women? Take our quiz to find out!
Does hormone replacement therapy have any effect on treatment for IBD among postmenopausal women? Take our quiz to find out!
Does hormone replacement therapy...
05/22/2025
Advances in Inflammatory Bowel Disease Network
Quiz
Upper GI Crohn's Disease
03/18/2025
Rebecca Mashaw
How much do you know about upper GI Crohn's disease? Take our quiz to check your knowledge!
How much do you know about upper GI Crohn's disease? Take our quiz to check your knowledge!
How much do you know about upper...
03/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
Preoperative Nutrition for Crohn’s Disease Patients
03/18/2025
Rebecca Mashaw
What is one benefit of preoperative exclusive enteral nutrition for Crohn’s disease patients? Take our quiz to find out if you know the answer!
What is one benefit of preoperative exclusive enteral nutrition for Crohn’s disease patients? Take our quiz to find out if you know the answer!
What is one benefit of...
03/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
Risk Factors for Surgery in Crohn’s Disease
02/26/2025
Rebecca Mashaw
Estimates vary but indicate that half or more of patients with Crohn's disease will require surgery at some point in their disease course. Do you know which factors place your patients at high risk for surgery? Take our quiz to find out!
Estimates vary but indicate that half or more of patients with Crohn's disease will require surgery at some point in their disease course. Do you know which factors place your patients at high risk for surgery? Take our quiz to find out!
Estimates vary but indicate that...
02/26/2025
Advances in Inflammatory Bowel Disease Network

Insights

Miguel Regueiro MD
Conference coverage
Miguel Regueiro, MD, on Updates in Treatment of Perianal Crohn's Disease
05/12/2025
Miguel D. Regueiro, MD
Dr Regueiro reviews his presentation of the Patricia and Ralph Gianella lecture from DDW 2025 on the updates to the treatment algorithm for perianal Crohn's disease.
Dr Regueiro reviews his presentation of the Patricia and Ralph Gianella lecture from DDW 2025 on the updates to the treatment algorithm for perianal Crohn's disease.
Dr Regueiro reviews his...
05/12/2025
Advances in Inflammatory Bowel Disease Network
Ed Barnes
Conference coverage
Edward Barnes, MD, on Penetrating and Stricturing Crohn's Disease
05/09/2025
Edward L. Barnes
Dr Barnes reviews the key points of his presentation from the AIBD regional meeting on managing penetrating and stricturing complications of Crohn's disease.
Dr Barnes reviews the key points of his presentation from the AIBD regional meeting on managing penetrating and stricturing complications of Crohn's disease.
Dr Barnes reviews the key points...
05/09/2025
Advances in Inflammatory Bowel Disease Network
Marla Dubinsky
Conference coverage
Marla Dubinsky, MD, on Risk Stratification in Crohn's Disease
01/16/2025
Dr Dubinsky opened the 2024 Advances in Inflammatory Bowel Disease conference with a firm statement that virtually all patients with Crohn's disease should be treated quickly after diagnosis with approved and effective therapies to help...
Dr Dubinsky opened the 2024 Advances in Inflammatory Bowel Disease conference with a firm statement that virtually all patients with Crohn's disease should be treated quickly after diagnosis with approved and effective therapies to help...
Dr Dubinsky opened the 2024...
01/16/2025
Advances in Inflammatory Bowel Disease Network
Anthony de Buck
Conference coverage
Anthony de Buck, MD, on Positioning Surgery for Crohn's Disease
12/10/2024
Dr de Buck explains how early surgery may be an excellent option in Crohn's disease, when to provide adjuvant medical therapy, monitoring patients after procedures, and that the type of surgery is less important than the timing.
Dr de Buck explains how early surgery may be an excellent option in Crohn's disease, when to provide adjuvant medical therapy, monitoring patients after procedures, and that the type of surgery is less important than the timing.
Dr de Buck explains how early...
12/10/2024
Advances in Inflammatory Bowel Disease Network
Jim Lewis
Videos
James Lewis, MD, on Diet and Nutrition in Crohn's Disease
12/09/2024
James D. Lewis
Dr James Lewis, from the University of Pennsylvania, recaps his presentation on using diet as an adjunct to medical therapy for Crohn's disease, and its potential to induce remission and even prevent IBD among those at high risk.
Dr James Lewis, from the University of Pennsylvania, recaps his presentation on using diet as an adjunct to medical therapy for Crohn's disease, and its potential to induce remission and even prevent IBD among those at high risk.
Dr James Lewis, from the...
12/09/2024
Advances in Inflammatory Bowel Disease Network
Video
Remo Panaccione, MD, on the GRAVITI Trials of Guselkumab in Crohn's Disease
12/02/2024
Dr Panaccione reviews the latest trial results for guselkumab in treating Crohn's disease, showing that both IV and subcutaneous induction are superior to placebo.
Dr Panaccione reviews the latest trial results for guselkumab in treating Crohn's disease, showing that both IV and subcutaneous induction are superior to placebo.
Dr Panaccione reviews the latest...
12/02/2024
Advances in Inflammatory Bowel Disease Network
Phillip Gu
Video
Phillip Gu, MD, on Preventing Postoperative Crohn's Disease Recurrence
09/11/2024
Dr Gu reviews his address at the AIBD regional meeting on the recurrence of postoperative Crohn's disease, including how to assess risks and steps that can help to prevent it.
Dr Gu reviews his address at the AIBD regional meeting on the recurrence of postoperative Crohn's disease, including how to assess risks and steps that can help to prevent it.
Dr Gu reviews his address at the...
09/11/2024
Advances in Inflammatory Bowel Disease Network
Florian Rieder
Video
Florian Rieder, MD, on Optimizing Outcomes in Crohn's Disease
08/21/2024
Dr Rieder reviews the options for treatment of Crohn's disease in terms of safety, treatment of comorbidities, and efficacy for moderate to severe disease.
Dr Rieder reviews the options for treatment of Crohn's disease in terms of safety, treatment of comorbidities, and efficacy for moderate to severe disease.
Dr Rieder reviews the options...
08/21/2024
Advances in Inflammatory Bowel Disease Network
Ed Loftus
Video
Edward Loftus, MD, on Upadacitinib in Crohn's Disease
06/06/2024
Dr Loftus recaps his poster presentation on a subanalysis from the upadacitinib phase 3 trials in Crohn's disease examining the effect on anxiety, depression, fatigue, and bowel urgency.
Dr Loftus recaps his poster presentation on a subanalysis from the upadacitinib phase 3 trials in Crohn's disease examining the effect on anxiety, depression, fatigue, and bowel urgency.
Dr Loftus recaps his poster...
06/06/2024
Advances in Inflammatory Bowel Disease Network
Miguel D. Regueiro
Conference Coverage
Miguel Regueiro, MD, on Postoperative Crohn's Disease
05/15/2024
Miguel D. Regueiro, MD
Dr Regueiro recaps his keynote address on the management postoperative Crohn's disease, including new surgical techniques and medications that could help prevent the occurrence of postoperative disease.
Dr Regueiro recaps his keynote address on the management postoperative Crohn's disease, including new surgical techniques and medications that could help prevent the occurrence of postoperative disease.
Dr Regueiro recaps his keynote...
05/15/2024
Advances in Inflammatory Bowel Disease Network
Conference Coverage
AIBD Poster Award Winner: Katherine Cates, MD
01/24/2026
Dr Cates describes her award-winning poster on the use of anal pap smears to identify patients at high risk of developing anal cancer and advance them to high-resolution anometry.
Dr Cates describes her award-winning poster on the use of anal pap smears to identify patients at high risk of developing anal cancer and advance them to high-resolution anometry.
Dr Cates describes her...
01/24/2026
Advances in Inflammatory Bowel Disease Network
Conference Coverage
AIBD Poster Award Winner: Dana Neugut, MD
01/24/2026
Dana Neugut, MD
Dr Neugut reviews her award-winning poster from AIBD on the association of Childhood Opportunity Index with time to infliximab discontinuation in pediatric patients with inflammatory bowel disease.
Dr Neugut reviews her award-winning poster from AIBD on the association of Childhood Opportunity Index with time to infliximab discontinuation in pediatric patients with inflammatory bowel disease.
Dr Neugut reviews her...
01/24/2026
Advances in Inflammatory Bowel Disease Network
Conference Coverage
AIBD Poster Award Winner: Ece Unal, MD
01/20/2026
Ece Unal, MD
Cleveland Clinic surgery resident Ece Unal, MD, gives an overview of her award-winning poster on a systematic review of excision of skin tags in perianal Crohn’s Disease, presented at the AIBD Annual Meeting.
Cleveland Clinic surgery resident Ece Unal, MD, gives an overview of her award-winning poster on a systematic review of excision of skin tags in perianal Crohn’s Disease, presented at the AIBD Annual Meeting.
Cleveland Clinic surgery...
01/20/2026
Advances in Inflammatory Bowel Disease Network
From the AIBD Open Air Studio
AIBD Poster Award Winner: Wei Wei Lee, MD
01/20/2026
Wei Wei Lee, MD
Dr Lee describes her award-winning poster presentation on the frequency of changes in diagnosis from ulcerative colitis to Crohn's disease among pediatric patients.
Dr Lee describes her award-winning poster presentation on the frequency of changes in diagnosis from ulcerative colitis to Crohn's disease among pediatric patients.
Dr Lee describes her...
01/20/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Raymond Cross, MD, on Ostomy Complications
01/13/2026
Raymond Cross, MD; Sara Horst, MD
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive...
01/13/2026
Advances in Inflammatory Bowel Disease Network
Oriana Damas
From the AIBD Open Air Studio
The Sherman Emerging Leader Award: Oriana Damas, MD
12/29/2025
Oriana Damas, MD, MSCTI
Awarded the Sherman Emerging Leader Prize at the Advances in IBD annual meeting, Dr Oriana Damas encouraged others to use passion, dedication, and vision to move the field forward.
Awarded the Sherman Emerging Leader Prize at the Advances in IBD annual meeting, Dr Oriana Damas encouraged others to use passion, dedication, and vision to move the field forward.
Awarded the Sherman Emerging...
12/29/2025
Advances in Inflammatory Bowel Disease Network
Michael Kappelman
From the AIBD Open Air Studio
The Sherman Prize: Michael Kappelman, MD
12/29/2025
Michael Kappelman, MD
Dr Michael Kappelman, one of the Sherman Prize winners for 2025, speaks from the Open Air Studio at the Advances in IBD meeting about his clinical and research work with pediatric patients with ulcerative colitis or Crohn's disease.
Dr Michael Kappelman, one of the Sherman Prize winners for 2025, speaks from the Open Air Studio at the Advances in IBD meeting about his clinical and research work with pediatric patients with ulcerative colitis or Crohn's disease.
Dr Michael Kappelman, one of the...
12/29/2025
Advances in Inflammatory Bowel Disease Network
Scott Snapper
From the AIBD Open Air Studio
The Sherman Prize: Scott Snapper, MD
12/29/2025
Scott Snapper, MD
Sherman Prize winner Dr Scott Snapper reviewed his team's work on the genetics associated with IBD in children from the Open Air Studio at the Advances in IBD annual meeting.
Sherman Prize winner Dr Scott Snapper reviewed his team's work on the genetics associated with IBD in children from the Open Air Studio at the Advances in IBD annual meeting.
Sherman Prize winner Dr Scott...
12/29/2025
Advances in Inflammatory Bowel Disease Network
Corey & Miguel
From the AIBD Open Air Studio
Optimize or Switch Therapy? Siegel vs Regueiro Debate
12/23/2025
Miguel D. Regueiro, MD; Corey A. Siegel, MD, MS
For the 9th year, Drs Miguel Regueiro and Corey Siegel both claim victory in their annual debate—this time, about switching vs optimizing therapies—and remain friends.
For the 9th year, Drs Miguel Regueiro and Corey Siegel both claim victory in their annual debate—this time, about switching vs optimizing therapies—and remain friends.
For the 9th year, Drs Miguel...
12/23/2025
Advances in Inflammatory Bowel Disease Network
Ray Cross and Tina Ha
From the AIBD Open Air Studio
IBD Drive Time: Christina Ha, MD, on Positioning IBD Therapies
12/23/2025
Raymond Cross, MD; Christina Ha, MD
In the first-ever video version of the IBD Drive Time podcast, Drs Raymond Cross and Christina Ha discuss positioning IBD therapies from our Open Air Studio at the AIBD Annual Meeting.
In the first-ever video version of the IBD Drive Time podcast, Drs Raymond Cross and Christina Ha discuss positioning IBD therapies from our Open Air Studio at the AIBD Annual Meeting.
In the first-ever video version...
12/23/2025
Advances in Inflammatory Bowel Disease Network

Latest News

Research Highlights
Upadacitinib Improves Outcomes in Fistulizing Crohn’s Disease
09/04/2025
Rebecca Mashaw
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing...
09/04/2025
Advances in Inflammatory Bowel Disease Network
News
Validation of a Simple Ultrasound Score for Crohn’s Disease
08/28/2025
Rebecca Mashaw
A multicenter study confirms the accuracy and reliability of a simplified ultrasound score for assessing Crohn’s disease activity.
A multicenter study confirms the accuracy and reliability of a simplified ultrasound score for assessing Crohn’s disease activity.
A multicenter study confirms the...
08/28/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Real-World Effectiveness and Safety of Risankizumab in Crohn’s Disease
08/21/2025
Rebecca Mashaw
Risankizumab demonstrates sustained clinical benefit and favorable safety in Crohn’s disease, including among ustekinumab-experienced patients.
Risankizumab demonstrates sustained clinical benefit and favorable safety in Crohn’s disease, including among ustekinumab-experienced patients.
Risankizumab demonstrates...
08/21/2025
Advances in Inflammatory Bowel Disease Network
News
Terminal Ileum Resection in Crohn’s Disease Linked to Increased Colorectal Cancer Risk
07/29/2025
Jessica Garlewicz
Further studies are warranted to explore the underlying mechanisms and to refine screening strategies based on individualized risk.
Further studies are warranted to explore the underlying mechanisms and to refine screening strategies based on individualized risk.
Further studies are warranted to...
07/29/2025
Gastroenterology
Research Highlights
Advanced Therapies Show Greater Efficacy in Colonic vs Ileal Crohn’s Disease
07/24/2025
Rebecca Mashaw
In a meta-analysis of 14 randomized clinical trials, Janus kinase inhibitors and other advanced therapies demonstrated significantly higher efficacy in colonic compared to ileal Crohn’s disease.
In a meta-analysis of 14 randomized clinical trials, Janus kinase inhibitors and other advanced therapies demonstrated significantly higher efficacy in colonic compared to ileal Crohn’s disease.
In a meta-analysis of 14...
07/24/2025
Advances in Inflammatory Bowel Disease Network
News
Guselkumab Induction and SC Maintenance Shows Efficacy and Safety in Crohn’s Disease
07/24/2025
Rebecca Mashaw
In both trials, guselkumab significantly surpassed placebo for primary composite endpoints of clinical response at week 12 followed by either clinical remission or endoscopic response at week 48.
In both trials, guselkumab significantly surpassed placebo for primary composite endpoints of clinical response at week 12 followed by either clinical remission or endoscopic response at week 48.
In both trials, guselkumab...
07/24/2025
Advances in Inflammatory Bowel Disease Network
News
Stricture-Related Resections Rising in Crohn’s Disease Despite Overall Decline in Surgical Rates
05/29/2025
Jessica Garlewicz
The study aimed to assess longitudinal trends in crohn's disease-related bowel surgeries, particularly for obstruction, following the introduction of infliximab in 1998.
The study aimed to assess longitudinal trends in crohn's disease-related bowel surgeries, particularly for obstruction, following the introduction of infliximab in 1998.
The study aimed to assess...
05/29/2025
Advances in Inflammatory Bowel Disease Network
News
MASLD Linked to Worse Clinical Outcomes in Hospitalized Crohn’s Disease Patients
04/03/2025
Jessica Garlewicz
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409 hospitalizations for Crohn's disease, of which 26,229 (3.3%) involved patients with coexisting metabolic dysfunction-associated steatotic liver disease.
A new study examined 792,409...
04/03/2025
Gastroenterology
News
Early Response to Upadacitinib Predicts Long-Term Improvements in Crohn’s Disease
04/03/2025
Jessica Garlewicz
Patients with early response achieved higher rates of clinical remission and reductions in fatigue and impairment.
Patients with early response achieved higher rates of clinical remission and reductions in fatigue and impairment.
Patients with early response...
04/03/2025
Advances in Inflammatory Bowel Disease Network
News
VCE-Guided Treat-to-Target Strategy Reduces Flares in Crohn’s Disease Remission
04/01/2025
Jessica Garlewicz
The study highlights the utility of mucosal assessment in driving treatment optimization, even in asymptomatic patients.
The study highlights the utility of mucosal assessment in driving treatment optimization, even in asymptomatic patients.
The study highlights the utility...
04/01/2025
Advances in Inflammatory Bowel Disease Network
Research Review
New Meta-Analysis Highlights Burden of MASLD Among IBD Patients
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
News
Medicare Will Cover GLP-1s for Obesity Under Deal with Pharma
11/06/2025
Rebecca Mashaw
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said...
11/06/2025
Advances in Inflammatory Bowel Disease Network
FDA alert
FDA Alert
FDA Approves Updated Indication for Upadacitinib in IBD
10/14/2025
Rebecca Mashaw
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for...
10/14/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Concomitant Medications Do Not Alter Efficacy of Advanced Therapies in Ulcerative Colitis, Study Finds
09/18/2025
Jessica Garlewicz
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that...
09/18/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Persistent Prothrombotic State Observed in Patients With ASUC
09/04/2025
Rebecca Mashaw
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Upadacitinib Improves Outcomes in Fistulizing Crohn’s Disease
09/04/2025
Rebecca Mashaw
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Pelvic MRI Detects Subclinical Perianal Disease in Pediatric Crohn’s Disease
09/04/2025
Jessica Garlewicz
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Mirikizumab Improves Quality of Life and Work Productivity in Moderate to Severe Crohn’s Disease
09/04/2025
Jessica Garlewicz
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Risankizumab Improves Symptom Resolution and Quality of Life in Ulcerative Colitis
09/04/2025
Jessica Garlewicz
Risankizumab led to earlier and sustained improvements in individual symptoms—including abdominal pain, bowel urgency, fecal incontinence, and sleep interruption
Risankizumab led to earlier and sustained improvements in individual symptoms—including abdominal pain, bowel urgency, fecal incontinence, and sleep interruption
Risankizumab led to earlier and...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Guselkumab Demonstrates Efficacy and Safety in Moderate-to-Severe Crohn’s Disease
09/04/2025
Jessica Garlewicz
The study met all primary and multiplicity-controlled secondary endpoints, including clinical and endoscopic outcomes through 48 weeks.
The study met all primary and multiplicity-controlled secondary endpoints, including clinical and endoscopic outcomes through 48 weeks.
The study met all primary and...
09/04/2025
Advances in Inflammatory Bowel Disease Network

Latest Podcasts

IBD Drive time logo
Expert Insights
IBD Drive Time: Raymond Cross, MD, on Ostomy Complications
01/13/2026
Raymond Cross, MD; Sara Horst, MD
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive...
01/13/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Conference Coverage
IBD Drive Time: The Best of ACG With Dr Sara Horst
12/01/2025
Raymond Cross, MD; Sara Horst, MD
Dr Sara Horst joins IBD Drive Time host Dr Raymond Cross to review their choices for the best presentations from the American College of Gastroenterology annual meeting.
Dr Sara Horst joins IBD Drive Time host Dr Raymond Cross to review their choices for the best presentations from the American College of Gastroenterology annual meeting.
Dr Sara Horst joins IBD Drive...
12/01/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive Time
Podcast
IBD Drive Time: Freddy Caldera, MD, on Vaccines for Patients With IBD
11/03/2025
Raymond Cross, MD; Freddy Caldera, DO
Freddy Caldera, DO, returns to talk to IBD Drive Time host Raymond Cross, MD, about the best current recommendations for patients with IBD in the midst of controversy and confusion.
Freddy Caldera, DO, returns to talk to IBD Drive Time host Raymond Cross, MD, about the best current recommendations for patients with IBD in the midst of controversy and confusion.
Freddy Caldera, DO, returns to...
11/03/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive Time
Podcast
IBD Drive Time: Megan Riehl, PsyD, on Mental Health and IBD
10/22/2025
Raymond Cross, MD; Megan Riehl, PsyD
Clinical psychologist Megan Riehl, Psy D, talks with IBD Drive Time host Raymond Cross, MD, about the prevalence of anxiety and depression and even post-traumatic stress disorder among patients with inflammatory bowel disease--and how...
Clinical psychologist Megan Riehl, Psy D, talks with IBD Drive Time host Raymond Cross, MD, about the prevalence of anxiety and depression and even post-traumatic stress disorder among patients with inflammatory bowel disease--and how...
Clinical psychologist Megan...
10/22/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive Time
Podcast
IBD Drive Time: Florian Rieder, MD, on Stricturing and Penetrating Crohn's Disease
10/06/2025
Raymond Cross, MD; Florian Rieder
Host Raymond Cross, MD, welcomes back Dr Florian Rieder, an internationally recognized expert in penetrating and stricturing complications of Crohn's disease, to talk about diagnosing, performing endoscopy, and treating this challenging...
Host Raymond Cross, MD, welcomes back Dr Florian Rieder, an internationally recognized expert in penetrating and stricturing complications of Crohn's disease, to talk about diagnosing, performing endoscopy, and treating this challenging...
Host Raymond Cross, MD, welcomes...
10/06/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Jason Schairer, MD, on Extraintestinal Manifestations in IBD
09/25/2025
Jason Schairer, MD; Raymond Cross, MD
Host Raymond Cross, MD, and guest Dr Jason Schairer discuss the varieties of extraintestinal manifestations that may be seen in patients with IBD, how to diagnose them and when to rely on colleagues in dermatology, ophthalmology, and...
Host Raymond Cross, MD, and guest Dr Jason Schairer discuss the varieties of extraintestinal manifestations that may be seen in patients with IBD, how to diagnose them and when to rely on colleagues in dermatology, ophthalmology, and...
Host Raymond Cross, MD, and...
09/25/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
Ryan Ungaro, MD, on Perturbances in Metabolic Pathways in IBD
09/02/2025
Raymond Cross, MD; Ryan Ungaro
Dr Raymond Cross discusses with Dr Ryan Ungaro how the Mount Sinai Crohn's and Colitis Registry, a prospective observational cohort, is being studied to determine if its detailed clinical information and omics data collected can identify new...
Dr Raymond Cross discusses with Dr Ryan Ungaro how the Mount Sinai Crohn's and Colitis Registry, a prospective observational cohort, is being studied to determine if its detailed clinical information and omics data collected can identify new...
Dr Raymond Cross discusses with...
09/02/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive Time
Podcast
IBD Drive Time: Anita Afzali, MD, on the ACG Guidelines for Crohn's Disease
08/18/2025
Raymond Cross, MD; Anita Afzali
Dr Anita Afzali reviews with Dr Raymond Cross the updated guidelines for managing Crohn's disease from the American College of Gastroenterology,
Dr Anita Afzali reviews with Dr Raymond Cross the updated guidelines for managing Crohn's disease from the American College of Gastroenterology,
Dr Anita Afzali reviews with Dr...
08/18/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: David Rubin, MD, on the ACG Guidelines for Ulcerative Colitis
08/04/2025
David T. Rubin, MD; Raymond Cross, MD
Host Raymond Cross, MD, discusses the updates in the American College of Gastroenterology guideline on managing ulcerative colitis with first author David Rubin, MD.
Host Raymond Cross, MD, discusses the updates in the American College of Gastroenterology guideline on managing ulcerative colitis with first author David Rubin, MD.
Host Raymond Cross, MD,...
08/04/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Corey Siegel, MD, on Defining Quality Care for IBD
07/15/2025
Raymond Cross, MD; Corey A. Siegel, MD, MS
Host Raymond Cross, MD, and Dr Corey Siegel delve into the factors that constitute quality care for patients with IBD today, and how the definition of quality care has evolved over time.
Host Raymond Cross, MD, and Dr Corey Siegel delve into the factors that constitute quality care for patients with IBD today, and how the definition of quality care has evolved over time.
Host Raymond Cross, MD, and Dr...
07/15/2025
Advances in Inflammatory Bowel Disease Network

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