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Ulcerative Colitis

Ulcerative Colitis
Excellence Forum
Leaders in the field sharing authoritative insights and institutional best practices.

Maria Abreu
Research Insights
Maria Abreu, MD, on the DUET-UC Trial of Combination Therapy
05/19/2026
Maria Abreu, MD
Dr Abreu recaps the results of a late breaking abstract from Digestive Disease Week on the DUET-UC study, which tested whether a combination of two advanced therapies showed an additive or synergistic effect in patients refractory ulcerative...
Dr Abreu recaps the results of a late breaking abstract from Digestive Disease Week on the DUET-UC study, which tested whether a combination of two advanced therapies showed an additive or synergistic effect in patients refractory ulcerative...
Dr Abreu recaps the results of a...
05/19/2026
Advances in Inflammatory Bowel Disease Network
Jean-Frederic Colombel
Expert Insights
Jean-Frederic Colombel, MD, on Disease Clearance With Mirikizumab in Ulcerative Colitis
05/06/2026
Jean-Frederic Colombel
Dr Colombel discusses his presentation at DDW 2026 on a post-doc analysis of the long-term outcomes of the LUCENT trial of mirikizumab, which showed that the IL-23p19 inhibitor achieved and maintained disease clearance for up to 4 years among...
Dr Colombel discusses his presentation at DDW 2026 on a post-doc analysis of the long-term outcomes of the LUCENT trial of mirikizumab, which showed that the IL-23p19 inhibitor achieved and maintained disease clearance for up to 4 years among...
Dr Colombel discusses his...
05/06/2026
Advances in Inflammatory Bowel Disease Network
Stephen Hanauer
Conference Coverage
Stephen Hanauer, MD on Optimizing Early Management of Ulcerative Colitis
12/12/2025
Stephen B. Hanauer, MD
A targeted, risk-stratified approach helps to ensure the best outcomes in treating ulcerative colitis, Dr Hanauer stated.
A targeted, risk-stratified approach helps to ensure the best outcomes in treating ulcerative colitis, Dr Hanauer stated.
A targeted, risk-stratified...
12/12/2025
Advances in Inflammatory Bowel Disease Network
Ed Loftus
Conference Coverage
Edward Loftus, MD, on Recognizing and Managing Smoldering Ulcerative Colitis
12/12/2025
Edward V. Loftus, Jr., MD
Dr Loftus discussed the importance of recognizing that patients with ulcerative colitis may have subclinical--and damaging--inflammation in the absence of symptoms in his address at the 2025 AIBD Annual Meeting.
Dr Loftus discussed the importance of recognizing that patients with ulcerative colitis may have subclinical--and damaging--inflammation in the absence of symptoms in his address at the 2025 AIBD Annual Meeting.
Dr Loftus discussed the...
12/12/2025
Advances in Inflammatory Bowel Disease Network
Vipul Jairath
Conference Coverage
Vipul Jairath, MBChB, on the ANTHEM Study of Icotrokinra in UC
11/05/2025
Vipul Jairath, MD
Dr Jairath discusses the phase 2B study results of icotrokinra, a novel, oral interleukin-23 peptide, for the treatment of moderately to severely active ulcerative colitis, which were presented at the ACG 2025 Scientific Meeting.
Dr Jairath discusses the phase 2B study results of icotrokinra, a novel, oral interleukin-23 peptide, for the treatment of moderately to severely active ulcerative colitis, which were presented at the ACG 2025 Scientific Meeting.
Dr Jairath discusses the phase...
11/05/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: David Rubin, MD, on the ACG Guidelines for Ulcerative Colitis
08/04/2025
David T. Rubin, MD; Raymond Cross, MD
Host Raymond Cross, MD, discusses the updates in the American College of Gastroenterology guideline on managing ulcerative colitis with first author David Rubin, MD.
Host Raymond Cross, MD, discusses the updates in the American College of Gastroenterology guideline on managing ulcerative colitis with first author David Rubin, MD.
Host Raymond Cross, MD,...
08/04/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Edward Barnes, MD, on Pouch Complications
05/09/2025
Edward L. Barnes
Guest host Sara Horst, MD, and Dr Edward Barnes discuss complications of ileal pouch-anal anastamosis surgery and whether recent use of antibiotics puts patients at risk of pouchitis.
Guest host Sara Horst, MD, and Dr Edward Barnes discuss complications of ileal pouch-anal anastamosis surgery and whether recent use of antibiotics puts patients at risk of pouchitis.
Guest host Sara Horst, MD, and...
05/09/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Frank Scott, MD, on the AGA Guidelines for Ulcerative Colitis Management
12/30/2024
In this IBD Drive Time podcast, Dr Frank Scott from the University of Colorado and host Dr Raymond Cross discuss updates in the AGA guidelines for ulcerative colitis.
In this IBD Drive Time podcast, Dr Frank Scott from the University of Colorado and host Dr Raymond Cross discuss updates in the AGA guidelines for ulcerative colitis.
In this IBD Drive Time podcast,...
12/30/2024
Advances in Inflammatory Bowel Disease Network
Maia Kayal
Video
Maia Kayal MD, on Strategies for Managing Patients When Mesalamine Fails
12/27/2024
Dr Kayal reviews the options available when patients with ulcerative colitis do not respond or lose response to mesalamine therapy, and the considerations of patient factors, patient preferences, and safety that should be taken into account.
Dr Kayal reviews the options available when patients with ulcerative colitis do not respond or lose response to mesalamine therapy, and the considerations of patient factors, patient preferences, and safety that should be taken into account.
Dr Kayal reviews the options...
12/27/2024
Advances in Inflammatory Bowel Disease Network
Millie Long
Conference coverage
Millie Long, MD, on Defining Disease Severity in Ulcerative Colitis
12/16/2024
Dr Millie Long discusses the difference between the "snapshot" of disease activity and the "movie" of disease severity, and the importance of carefully assessing severity when choosing therapies and developing monitoring strategies for...
Dr Millie Long discusses the difference between the "snapshot" of disease activity and the "movie" of disease severity, and the importance of carefully assessing severity when choosing therapies and developing monitoring strategies for...
Dr Millie Long discusses the...
12/16/2024
Advances in Inflammatory Bowel Disease Network

Latest News

Conference Coverage
Endoscopic Management of Obstructing Pouch Twist
10/24/2012
A presentation on the first successful endoscopic management of a twisted J-pouch won both a Presidential Poster Award and ACG Case Reports Journal Award at the ACG Scientific Meeting on October 24.
A presentation on the first successful endoscopic management of a twisted J-pouch won both a Presidential Poster Award and ACG Case Reports Journal Award at the ACG Scientific Meeting on October 24.
A presentation on the first...
10/24/2012
Advances in Inflammatory Bowel Disease Network
Research Highlights
Combined Ultrasound and Calprotectin at 3 Months Predict Postoperative Recurrence in Crohn’s Disease
05/07/2026
Jessica Garlewicz
High specificity and positive predictive value suggest that patients meeting both thresholds are at high risk for early recurrence and may need closer monitoring.
High specificity and positive predictive value suggest that patients meeting both thresholds are at high risk for early recurrence and may need closer monitoring.
High specificity and positive...
05/07/2026
Advances in Inflammatory Bowel Disease Network
News
Oral Icotrokinra Demonstrates Efficacy in Ulcerative Colitis Regardless of Prior Advanced Therapy Exposure
05/05/2026
Jessica Garlewicz
While response rates were generally higher in patients without prior advanced therapy failure, meaningful improvements were still seen in those with treatment-resistant disease.
While response rates were generally higher in patients without prior advanced therapy failure, meaningful improvements were still seen in those with treatment-resistant disease.
While response rates were...
05/05/2026
Advances in Inflammatory Bowel Disease Network
Research Review
Early “Top-Down” Therapy Reduces Long-Term Complications in Crohn’s Disease
05/05/2026
Jessica Garlewicz
Disease progression and hospitalizations were more common in the step-up group, with higher rates of stricturing and penetrating complications.
Disease progression and hospitalizations were more common in the step-up group, with higher rates of stricturing and penetrating complications.
Disease progression and...
05/05/2026
Advances in Inflammatory Bowel Disease Network
Research Review
Upper GI Crohn’s Disease Remains Underrecognized, Lacks Standardized Guidance
04/02/2026
Jessica Garlewicz
A recent review noted a lack of consistent diagnostic definitions across modalities, complicating clinical interpretation and research comparisons.
A recent review noted a lack of consistent diagnostic definitions across modalities, complicating clinical interpretation and research comparisons.
A recent review noted a lack of...
04/02/2026
Advances in Inflammatory Bowel Disease Network
Research Summary
Advanced Therapy May Reduce Antibiotic Dependence in Chronic Pouchitis After IPAA
03/18/2026
Jessica Garlewicz
These findings support considering immune-mediated therapy in selected patients although more research is needed to identify the patients likely to benefit most from advanced therapy.
These findings support considering immune-mediated therapy in selected patients although more research is needed to identify the patients likely to benefit most from advanced therapy.
These findings support...
03/18/2026
Advances in Inflammatory Bowel Disease Network
Research Review
New Meta-Analysis Highlights Burden of MASLD Among IBD Patients
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
News
Medicare Will Cover GLP-1s for Obesity Under Deal with Pharma
11/06/2025
Rebecca Mashaw
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said...
11/06/2025
Advances in Inflammatory Bowel Disease Network
FDA alert
FDA Alert
FDA Approves Updated Indication for Upadacitinib in IBD
10/14/2025
Rebecca Mashaw
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for...
10/14/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Concomitant Medications Do Not Alter Efficacy of Advanced Therapies in Ulcerative Colitis, Study Finds
09/18/2025
Jessica Garlewicz
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that...
09/18/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
Persistent Prothrombotic State Observed in Patients With ASUC
09/04/2025
Rebecca Mashaw
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with...
09/04/2025
Advances in Inflammatory Bowel Disease Network

Latest Podcasts

IBD Drive time logo
Podcast
IBD Drive Time: David Rubin, MD, on the ACG Guidelines for Ulcerative Colitis
08/04/2025
David T. Rubin, MD; Raymond Cross, MD
Host Raymond Cross, MD, discusses the updates in the American College of Gastroenterology guideline on managing ulcerative colitis with first author David Rubin, MD.
Host Raymond Cross, MD, discusses the updates in the American College of Gastroenterology guideline on managing ulcerative colitis with first author David Rubin, MD.
Host Raymond Cross, MD,...
08/04/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Edward Barnes, MD, on Pouch Complications
05/09/2025
Edward L. Barnes
Guest host Sara Horst, MD, and Dr Edward Barnes discuss complications of ileal pouch-anal anastamosis surgery and whether recent use of antibiotics puts patients at risk of pouchitis.
Guest host Sara Horst, MD, and Dr Edward Barnes discuss complications of ileal pouch-anal anastamosis surgery and whether recent use of antibiotics puts patients at risk of pouchitis.
Guest host Sara Horst, MD, and...
05/09/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Frank Scott, MD, on the AGA Guidelines for Ulcerative Colitis Management
12/30/2024
In this IBD Drive Time podcast, Dr Frank Scott from the University of Colorado and host Dr Raymond Cross discuss updates in the AGA guidelines for ulcerative colitis.
In this IBD Drive Time podcast, Dr Frank Scott from the University of Colorado and host Dr Raymond Cross discuss updates in the AGA guidelines for ulcerative colitis.
In this IBD Drive Time podcast,...
12/30/2024
Advances in Inflammatory Bowel Disease Network
Millie Long
Video
Millie Long, MD, on Comparative Effectiveness in Ulcerative Colitis
10/21/2024
Dr Long reviews her presentation from the AIBD regional meeting on using comparative effectiveness data to choose from among the growing number of therapies for treating ulcerative colitis.
Dr Long reviews her presentation from the AIBD regional meeting on using comparative effectiveness data to choose from among the growing number of therapies for treating ulcerative colitis.
Dr Long reviews her presentation...
10/21/2024
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Erin Forster, MD, on Risankizumab for Ulcerative Colitis
09/03/2024
Erin Forster, MD, MPH; Millie D. Long, MD, MPH; Raymond Cross, MD
Dr Erin Forster of the Medical University of South Carolina joins IBD Drive Time hosts Dr Millie Long and Dr Raymond Cross to review results of the trials for risankizumab in ulcerative colitis and discuss its positioning in treatment.
Dr Erin Forster of the Medical University of South Carolina joins IBD Drive Time hosts Dr Millie Long and Dr Raymond Cross to review results of the trials for risankizumab in ulcerative colitis and discuss its positioning in treatment.
Dr Erin Forster of the Medical...
09/03/2024
Advances in Inflammatory Bowel Disease Network
Raymond Cross, MD
Podcast
Raymond Cross, MD: Define UC Disease Severity in Regard to Symptoms
02/26/2024
Dr Cross reviews the highlights of his presentation on recommendations for initial diagnostics and treatment in the care of the hospitalized patient with ulcerative colitis.
Dr Cross reviews the highlights of his presentation on recommendations for initial diagnostics and treatment in the care of the hospitalized patient with ulcerative colitis.
Dr Cross reviews the highlights...
02/26/2024
Advances in Inflammatory Bowel Disease Network
Raymond Cross, MD
Conference Coverage
Raymond Cross, MD, on S1Ps for Treatment of IBD
04/14/2023
S1Ps may work best for patients with moderate to more moderate-severe range of ulcerative colitis in the outpatient setting, particularly those earlier in their treatment journey, Dr Raymond Cross said during his presentation at the AIBD...
S1Ps may work best for patients with moderate to more moderate-severe range of ulcerative colitis in the outpatient setting, particularly those earlier in their treatment journey, Dr Raymond Cross said during his presentation at the AIBD...
S1Ps may work best for patients...
04/14/2023
Advances in Inflammatory Bowel Disease Network
David Hudesman
Podcast
David Hudesman, MD, on Efficacy of Tofacitinib Induction for Ulcerative Colitis
03/07/2023
Dr Hudesman reviews the findings of a post hoc analysis he and colleagues conducted to assess associations between C-reactive protein, partial Mayo score, and efficacy outcomes during tofacitinib induction.
Dr Hudesman reviews the findings of a post hoc analysis he and colleagues conducted to assess associations between C-reactive protein, partial Mayo score, and efficacy outcomes during tofacitinib induction.
Dr Hudesman reviews the findings...
03/07/2023
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Corey Siegel, MD, on Acute Severe Ulcerative Colitis
12/17/2022
12/17/2022
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Podcast
IBD Drive Time: Dr Corey Siegel on Acute Severe Ulcerative Colitis
11/03/2022
IBD Drive Time host Raymond Cross, MD, talks with Dr Corey Siegel about caring for patients with acute severe ulcerative colitis in the hospital and after discharge.
IBD Drive Time host Raymond Cross, MD, talks with Dr Corey Siegel about caring for patients with acute severe ulcerative colitis in the hospital and after discharge.
IBD Drive Time host Raymond...
11/03/2022
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Jennifer Seminerio, MD, on Advanced Combination Therapy
06/12/2026
Raymond Cross, MD; Jennifer Seminerio, MD
Drs Cross and Seminerio discuss advanced combination therapy, which involves use of more than one biologic or a biologic and an advanced small molecule, including trial results to date, types of combinations, safety considerations, and which...
Drs Cross and Seminerio discuss advanced combination therapy, which involves use of more than one biologic or a biologic and an advanced small molecule, including trial results to date, types of combinations, safety considerations, and which...
Drs Cross and Seminerio discuss...
06/12/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Jordan Axelrad, MD, on Communicating Risks to Patients With IBD
05/22/2026
Raymond Cross, MD; Jordan Axelrad, MD
Drs Raymond Cross and Jordan Axelrad provide guidance to clinicians about the best ways to put risks—both of uncontrolled IBD and of therapies—into perspective for patients.
Drs Raymond Cross and Jordan Axelrad provide guidance to clinicians about the best ways to put risks—both of uncontrolled IBD and of therapies—into perspective for patients.
Drs Raymond Cross and Jordan...
05/22/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Colleen Kelly, MD, on Obesity and IBD
04/20/2026
Raymond Cross, MD; Colleen Kelly, MD
Host Raymond Cross, MD, calls on Dr Colleen Kelly to discuss the increasing prevalence of obesity among patients with IBD, how obesity can complicate Crohn's disease and ulcerative colitis, and the role of GLP-1 RAs and bariatric surgery in...
Host Raymond Cross, MD, calls on Dr Colleen Kelly to discuss the increasing prevalence of obesity among patients with IBD, how obesity can complicate Crohn's disease and ulcerative colitis, and the role of GLP-1 RAs and bariatric surgery in...
Host Raymond Cross, MD, calls on...
04/20/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Jared Magee, MD, on Men's Health in IBD
04/07/2026
Raymond Cross, MD; Jared Magee, MD
Drs Raymond Cross and Jared Magee discuss some of the special concerns that affect men with inflammatory bowel disease, from cardiac concerns to sexual dysfunction and assessing for anal cancer.
Drs Raymond Cross and Jared Magee discuss some of the special concerns that affect men with inflammatory bowel disease, from cardiac concerns to sexual dysfunction and assessing for anal cancer.
Drs Raymond Cross and Jared...
04/07/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: The Best of ECCO 2026
03/25/2026
Raymond Cross, MD; Sara Horst, MD; Jordan Axelrad, MD
Host Raymond Cross, MD, is joined by Drs Sara Horst and Jordan Axelrad to review the findings of their picks for the best presentations from the European Crohn's and Colitis Organization meeting held earlier this year.
Host Raymond Cross, MD, is joined by Drs Sara Horst and Jordan Axelrad to review the findings of their picks for the best presentations from the European Crohn's and Colitis Organization meeting held earlier this year.
Host Raymond Cross, MD, is...
03/25/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Shirley Cohen-Mekelburg, MD on Self-Care for IBD Patients
03/17/2026
Shirley Cohen-Mekelburg; Raymond Cross, MD
Host Raymond Cross, MD, calls on Dr Shirley Mekelburg-Cohen to discuss the importance of self-care among patients with IBD, what self-care consists of, and how to help patients learn to partner with their clinicians in controlling their...
Host Raymond Cross, MD, calls on Dr Shirley Mekelburg-Cohen to discuss the importance of self-care among patients with IBD, what self-care consists of, and how to help patients learn to partner with their clinicians in controlling their...
Host Raymond Cross, MD, calls on...
03/17/2026
Advances in Inflammatory Bowel Disease Network
New IBD Logo
Expert Insights
IBD Drive Time: James Lewis, MD, on Dysplasia Surveillance in IBD
02/23/2026
Raymond Cross, MD; James D. Lewis, MD
Dr James Lewis from the University of Pennsylvania and host Dr Raymond Cross discuss the risk of colon cancer among patients with inflammatory bowel disease, the importance of appropriate surveillance, and special considerations for choosing...
Dr James Lewis from the University of Pennsylvania and host Dr Raymond Cross discuss the risk of colon cancer among patients with inflammatory bowel disease, the importance of appropriate surveillance, and special considerations for choosing...
Dr James Lewis from the...
02/23/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
IBD Drive Time: Raymond Cross, MD, on Ostomy Complications
01/13/2026
Raymond Cross, MD; Sara Horst, MD
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive...
01/13/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Conference Coverage
IBD Drive Time: The Best of ACG With Dr Sara Horst
12/01/2025
Raymond Cross, MD; Sara Horst, MD
Dr Sara Horst joins IBD Drive Time host Dr Raymond Cross to review their choices for the best presentations from the American College of Gastroenterology annual meeting.
Dr Sara Horst joins IBD Drive Time host Dr Raymond Cross to review their choices for the best presentations from the American College of Gastroenterology annual meeting.
Dr Sara Horst joins IBD Drive...
12/01/2025
Advances in Inflammatory Bowel Disease Network
IBD Drive Time
Podcast
IBD Drive Time: Freddy Caldera, MD, on Vaccines for Patients With IBD
11/03/2025
Raymond Cross, MD; Freddy Caldera, DO
Freddy Caldera, DO, returns to talk to IBD Drive Time host Raymond Cross, MD, about the best current recommendations for patients with IBD in the midst of controversy and confusion.
Freddy Caldera, DO, returns to talk to IBD Drive Time host Raymond Cross, MD, about the best current recommendations for patients with IBD in the midst of controversy and confusion.
Freddy Caldera, DO, returns to...
11/03/2025
Advances in Inflammatory Bowel Disease Network

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