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Advances in Inflammatory Bowel Disease Network

Featured

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Expert Insights
06/12/2026
Raymond Cross, MD; Jennifer Seminerio, MD
Drs Cross and Seminerio discuss advanced combination therapy, which involves use of more than one biologic or a biologic and an advanced small molecule, including trial results to date, types of combinations, safety considerations, and which...
Drs Cross and Seminerio discuss advanced combination therapy, which involves use of more than one biologic or a biologic and an advanced small molecule, including trial results to date, types of combinations, safety considerations, and which...
Drs Cross and Seminerio discuss...
06/12/2026
Advances in Inflammatory Bowel Disease Network
Research Review
06/11/2026
Jessica Garlewicz
A key theme of the narrative review is the disconnect between patients and healthcare providers regarding the importance of bowel urgency in Crohn's disease.
A key theme of the narrative review is the disconnect between patients and healthcare providers regarding the importance of bowel urgency in Crohn's disease.
A key theme of the narrative...
06/11/2026
Advances in Inflammatory Bowel Disease Network
Research Highlights
06/11/2026
Jessica Garlewicz
Investigators concluded that proactive disease management and continued use of effective therapies during pregnancy to control disease activity—not disease duration or age at diagnosis—is the primary determinant of neonatal outcomes in...
Investigators concluded that proactive disease management and continued use of effective therapies during pregnancy to control disease activity—not disease duration or age at diagnosis—is the primary determinant of neonatal outcomes in...
Investigators concluded that...
06/11/2026
AIBD NP/PA Institute
From AIBD NP/PA Institute
Research Report
06/11/2026
Jessica Garlewicz
The effect of biologic therapy in reducing risks of recurrence following surgery for Crohn’s disease was observed across patient subgroups, suggesting broad benefit regardless of individual risk profile, researchers reported.
The effect of biologic therapy in reducing risks of recurrence following surgery for Crohn’s disease was observed across patient subgroups, suggesting broad benefit regardless of individual risk profile, researchers reported.
The effect of biologic therapy...
06/11/2026
AIBD NP/PA Institute
From AIBD NP/PA Institute
Research Review
06/11/2026
Jessica Garlewicz
In the first human study to demonstrate distinct P-80 metabolism in patients with Crohn's disease, researchers found that "dietary sweeteners and P-80 metabolites showed significant correlations with disease activity.”
In the first human study to demonstrate distinct P-80 metabolism in patients with Crohn's disease, researchers found that "dietary sweeteners and P-80 metabolites showed significant correlations with disease activity.”
In the first human study to...
06/11/2026
Advances in Inflammatory Bowel Disease Network
Gil Melmed
Conference Coverage
06/01/2026
Gil Y. Melmed, MD
Dr Melmed reviews the prehabilitation protocol trialed at Cedars-Sinai among patients with IBD who were preparing for surgery, which showed a definite reduction in complications among the cohort that received multidisciplinary care as well as...
Dr Melmed reviews the prehabilitation protocol trialed at Cedars-Sinai among patients with IBD who were preparing for surgery, which showed a definite reduction in complications among the cohort that received multidisciplinary care as well as...
Dr Melmed reviews the...
06/01/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
05/22/2026
Raymond Cross, MD; Jordan Axelrad, MD
Drs Raymond Cross and Jordan Axelrad provide guidance to clinicians about the best ways to put risks—both of uncontrolled IBD and of therapies—into perspective for patients.
Drs Raymond Cross and Jordan Axelrad provide guidance to clinicians about the best ways to put risks—both of uncontrolled IBD and of therapies—into perspective for patients.
Drs Raymond Cross and Jordan...
05/22/2026
Advances in Inflammatory Bowel Disease Network
Bruce Sands
Expert Insights
05/19/2026
Bruce E. Sands, MD, MS
Dr Sands reviews the results of the DUET-CD study of combination therapy with guselkumab and golimumab in patients with Crohn's disease, which showed a significant increase in efficacy for the combination versus either drug independently.
Dr Sands reviews the results of the DUET-CD study of combination therapy with guselkumab and golimumab in patients with Crohn's disease, which showed a significant increase in efficacy for the combination versus either drug independently.
Dr Sands reviews the results of...
05/19/2026
Advances in Inflammatory Bowel Disease Network
Maria Abreu
Research Insights
05/19/2026
Maria Abreu, MD
Dr Abreu recaps the results of a late breaking abstract from Digestive Disease Week on the DUET-UC study, which tested whether a combination of two advanced therapies showed an additive or synergistic effect in patients refractory ulcerative...
Dr Abreu recaps the results of a late breaking abstract from Digestive Disease Week on the DUET-UC study, which tested whether a combination of two advanced therapies showed an additive or synergistic effect in patients refractory ulcerative...
Dr Abreu recaps the results of a...
05/19/2026
Advances in Inflammatory Bowel Disease Network
Research Review
05/15/2026
Jessica Garlewicz
Although the study was not powered to detect statistical significance, the findings suggest a potential benefit of incorporating drug levels into routine management.
Although the study was not powered to detect statistical significance, the findings suggest a potential benefit of incorporating drug levels into routine management.
Although the study was not...
05/15/2026
Advances in Inflammatory Bowel Disease Network
Research Highlights
05/13/2026
Any antibiotic exposure during childhood was associated with a 42% increased risk of later IBD compared with no exposure, the investigators reported.
Any antibiotic exposure during childhood was associated with a 42% increased risk of later IBD compared with no exposure, the investigators reported.
Any antibiotic exposure during...
05/13/2026
Advances in Inflammatory Bowel Disease Network

Interactive Features

Quiz
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
07/18/2025
Can hormone replacement therapy help or harm disease activity among women with IBD? Our quiz will show the answer!
Can hormone replacement therapy help or harm disease activity among women with IBD? Our quiz will show the answer!
Can hormone replacement therapy...
07/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/18/2025
Can a wearable sensor help monitor disease activity in IBD--via sweat? Take our quiz to get the answer.
Can a wearable sensor help monitor disease activity in IBD--via sweat? Take our quiz to get the answer.
Can a wearable sensor help...
07/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/01/2025
Rebecca Mashaw
Which of the following factors did clinicians say in a recent study is particularly important for EHR functionality in the context of IBD?
Which of the following factors did clinicians say in a recent study is particularly important for EHR functionality in the context of IBD?
Which of the following factors...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/01/2025
Rebecca Mashaw
According to a recent survey of clinicians who care for patients with inflammatory bowel disease, what percentage reported that their EHR system does not enhance patient care in IBD?
According to a recent survey of clinicians who care for patients with inflammatory bowel disease, what percentage reported that their EHR system does not enhance patient care in IBD?
According to a recent survey of...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/01/2025
Rebecca Mashaw
A multicenter Canadian study to evaluate advanced combination treatment (ACT) in patients with refractory inflammatory bowel disease (IBD) arrived at which of the following conclusions?
A multicenter Canadian study to evaluate advanced combination treatment (ACT) in patients with refractory inflammatory bowel disease (IBD) arrived at which of the following conclusions?
A multicenter Canadian study to...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/01/2025
A recent study evaluated the use of a wearable sensor to measure inflammatory biomarkers in perspiration as a noninvasive method for monitoring IBD activity. What did it show? Take our quiz to see if you know the answer!
A recent study evaluated the use of a wearable sensor to measure inflammatory biomarkers in perspiration as a noninvasive method for monitoring IBD activity. What did it show? Take our quiz to see if you know the answer!
A recent study evaluated the use...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
05/22/2025
Rebecca Mashaw
Does hormone replacement therapy have any effect on treatment for IBD among postmenopausal women? Take our quiz to find out!
Does hormone replacement therapy have any effect on treatment for IBD among postmenopausal women? Take our quiz to find out!
Does hormone replacement therapy...
05/22/2025
Advances in Inflammatory Bowel Disease Network
Quiz
03/18/2025
Rebecca Mashaw
How much do you know about upper GI Crohn's disease? Take our quiz to check your knowledge!
How much do you know about upper GI Crohn's disease? Take our quiz to check your knowledge!
How much do you know about upper...
03/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
03/18/2025
Rebecca Mashaw
What is one benefit of preoperative exclusive enteral nutrition for Crohn’s disease patients? Take our quiz to find out if you know the answer!
What is one benefit of preoperative exclusive enteral nutrition for Crohn’s disease patients? Take our quiz to find out if you know the answer!
What is one benefit of...
03/18/2025
Advances in Inflammatory Bowel Disease Network

Expert Insights

IBD Drive time logo
Expert Insights
06/12/2026
Raymond Cross, MD; Jennifer Seminerio, MD
Drs Cross and Seminerio discuss advanced combination therapy, which involves use of more than one biologic or a biologic and an advanced small molecule, including trial results to date, types of combinations, safety considerations, and which...
Drs Cross and Seminerio discuss advanced combination therapy, which involves use of more than one biologic or a biologic and an advanced small molecule, including trial results to date, types of combinations, safety considerations, and which...
Drs Cross and Seminerio discuss...
06/12/2026
Advances in Inflammatory Bowel Disease Network
Gil Melmed
Conference Coverage
06/01/2026
Gil Y. Melmed, MD
Dr Melmed reviews the prehabilitation protocol trialed at Cedars-Sinai among patients with IBD who were preparing for surgery, which showed a definite reduction in complications among the cohort that received multidisciplinary care as well as...
Dr Melmed reviews the prehabilitation protocol trialed at Cedars-Sinai among patients with IBD who were preparing for surgery, which showed a definite reduction in complications among the cohort that received multidisciplinary care as well as...
Dr Melmed reviews the...
06/01/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
05/22/2026
Raymond Cross, MD; Jordan Axelrad, MD
Drs Raymond Cross and Jordan Axelrad provide guidance to clinicians about the best ways to put risks—both of uncontrolled IBD and of therapies—into perspective for patients.
Drs Raymond Cross and Jordan Axelrad provide guidance to clinicians about the best ways to put risks—both of uncontrolled IBD and of therapies—into perspective for patients.
Drs Raymond Cross and Jordan...
05/22/2026
Advances in Inflammatory Bowel Disease Network
Bruce Sands
Expert Insights
05/19/2026
Bruce E. Sands, MD, MS
Dr Sands reviews the results of the DUET-CD study of combination therapy with guselkumab and golimumab in patients with Crohn's disease, which showed a significant increase in efficacy for the combination versus either drug independently.
Dr Sands reviews the results of the DUET-CD study of combination therapy with guselkumab and golimumab in patients with Crohn's disease, which showed a significant increase in efficacy for the combination versus either drug independently.
Dr Sands reviews the results of...
05/19/2026
Advances in Inflammatory Bowel Disease Network
Maria Abreu
Research Insights
05/19/2026
Maria Abreu, MD
Dr Abreu recaps the results of a late breaking abstract from Digestive Disease Week on the DUET-UC study, which tested whether a combination of two advanced therapies showed an additive or synergistic effect in patients refractory ulcerative...
Dr Abreu recaps the results of a late breaking abstract from Digestive Disease Week on the DUET-UC study, which tested whether a combination of two advanced therapies showed an additive or synergistic effect in patients refractory ulcerative...
Dr Abreu recaps the results of a...
05/19/2026
Advances in Inflammatory Bowel Disease Network
Miguel Regueiro MD
Research Review
05/13/2026
Miguel D. Regueiro, MD
Dr Regueiro reviews his presentation from Digestive Disease Week on the treatment of perianal Crohn's disease, including advances in medical therapies and surgical approaches. 
Dr Regueiro reviews his presentation from Digestive Disease Week on the treatment of perianal Crohn's disease, including advances in medical therapies and surgical approaches. 
Dr Regueiro reviews his...
05/13/2026
Advances in Inflammatory Bowel Disease Network
Stephen Hanauer
Conference Coverage
05/07/2026
Stephen B. Hanauer, MD
Dr Hanauer reviews the key themes that were discussed in sessions on inflammatory bowel diseases at Digestive Diseases Week 2026, including prevention, early treatment, and combination therapy.
Dr Hanauer reviews the key themes that were discussed in sessions on inflammatory bowel diseases at Digestive Diseases Week 2026, including prevention, early treatment, and combination therapy.
Dr Hanauer reviews the key...
05/07/2026
Advances in Inflammatory Bowel Disease Network
Jean-Frederic Colombel
Expert Insights
05/06/2026
Jean-Frederic Colombel
Dr Colombel discusses his presentation at DDW 2026 on a post-doc analysis of the long-term outcomes of the LUCENT trial of mirikizumab, which showed that the IL-23p19 inhibitor achieved and maintained disease clearance for up to 4 years among...
Dr Colombel discusses his presentation at DDW 2026 on a post-doc analysis of the long-term outcomes of the LUCENT trial of mirikizumab, which showed that the IL-23p19 inhibitor achieved and maintained disease clearance for up to 4 years among...
Dr Colombel discusses his...
05/06/2026
Advances in Inflammatory Bowel Disease Network
Ed Barnes
Conference Coverage
05/06/2026
Edward L. Barnes, MD
Dr Barnes reviewed his presentation of results from the VIVID 1 and VIVID 2 trials of mirkizumab in patients with Crohn's disease with exposure to anti-TNF therapy, which found that 65% of those in endoscopic response at week 52 maintained...
Dr Barnes reviewed his presentation of results from the VIVID 1 and VIVID 2 trials of mirkizumab in patients with Crohn's disease with exposure to anti-TNF therapy, which found that 65% of those in endoscopic response at week 52 maintained...
Dr Barnes reviewed his...
05/06/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
04/20/2026
Raymond Cross, MD; Colleen Kelly, MD
Host Raymond Cross, MD, calls on Dr Colleen Kelly to discuss the increasing prevalence of obesity among patients with IBD, how obesity can complicate Crohn's disease and ulcerative colitis, and the role of GLP-1 RAs and bariatric surgery in...
Host Raymond Cross, MD, calls on Dr Colleen Kelly to discuss the increasing prevalence of obesity among patients with IBD, how obesity can complicate Crohn's disease and ulcerative colitis, and the role of GLP-1 RAs and bariatric surgery in...
Host Raymond Cross, MD, calls on...
04/20/2026
Advances in Inflammatory Bowel Disease Network

Conference Coverage

Research Highlights
05/13/2026
Rebecca Mashaw
GALAXI 2 and 3 extension data suggest that escalating guselkumab maintenance dosing may safely improve clinical and endoscopic outcomes in Crohn’s disease patients with inadequate response.
GALAXI 2 and 3 extension data suggest that escalating guselkumab maintenance dosing may safely improve clinical and endoscopic outcomes in Crohn’s disease patients with inadequate response.
GALAXI 2 and 3 extension data...
05/13/2026
Advances in Inflammatory Bowel Disease Network
Research Highlights
05/13/2026
Jessica Garlewicz
Disease progression was more common in the cohort on step-up therapy, with higher rates of stricturing and penetrating complications and hospitalizations.
Disease progression was more common in the cohort on step-up therapy, with higher rates of stricturing and penetrating complications and hospitalizations.
Disease progression was more...
05/13/2026
Advances in Inflammatory Bowel Disease Network
Expert Insights
05/12/2026
Corey A. Siegel, MD, MS; Adam S. Cheifetz, MD
Drs Cheifetz and Siegel discuss an abstract presented at DDW on the value of "flipping the script" from traditional step-up therapy for IBD to using advanced therapy for virtually all Crohn's disease and ulcerative colitis patients.
Drs Cheifetz and Siegel discuss an abstract presented at DDW on the value of "flipping the script" from traditional step-up therapy for IBD to using advanced therapy for virtually all Crohn's disease and ulcerative colitis patients.
Drs Cheifetz and Siegel discuss...
05/12/2026
Advances in Inflammatory Bowel Disease Network
Research Review
05/08/2026
Jessica Garlewicz
FUZION is the first and only randomized, controlled trial to show efficacy of an IL-23p19 antagonist in perianal fistulizing Crohn’s disease and the first trial of any therapy for perianal Crohn's disease since 1999.
FUZION is the first and only randomized, controlled trial to show efficacy of an IL-23p19 antagonist in perianal fistulizing Crohn’s disease and the first trial of any therapy for perianal Crohn's disease since 1999.
FUZION is the first and only...
05/08/2026
Advances in Inflammatory Bowel Disease Network
Research Review
05/06/2026
Jessica Garlewicz
The study uniquely focused on patients with baseline bowel urgency, integrating symptom burden with objective mucosal healing endpoints.
The study uniquely focused on patients with baseline bowel urgency, integrating symptom burden with objective mucosal healing endpoints.
The study uniquely focused on...
05/06/2026
Advances in Inflammatory Bowel Disease Network
Research Highlights
05/06/2026
Jessica Garlewicz
Among vaccinated patients with active IBD, RSV infection rates were no longer significantly different compared with those with nonactive disease.
Among vaccinated patients with active IBD, RSV infection rates were no longer significantly different compared with those with nonactive disease.
Among vaccinated patients with...
05/06/2026
Advances in Inflammatory Bowel Disease Network
Research Highlights
05/06/2026
Jessica Garlewicz
Endoscopic and histologic improvements early in treatment appear to serve as reliable indicators of sustained remission without corticosteroids.
Endoscopic and histologic improvements early in treatment appear to serve as reliable indicators of sustained remission without corticosteroids.
Endoscopic and histologic...
05/06/2026
Advances in Inflammatory Bowel Disease Network
Best of 2025
From the AIBD Open Air Studio
12/18/2025
Marla C. Dubinsky, MD; Parambir Dulai, MD; Bruce E. Sands, MD, MS
Drs Marla Dubinsky, Bruce Sands, and Parambir Dulai inaugurated the Open Air Studio at the Advances in IBD 2025 annual meeting with a review of the best research and most promising advances in the treatment of inflammatory bowel disease...
Drs Marla Dubinsky, Bruce Sands, and Parambir Dulai inaugurated the Open Air Studio at the Advances in IBD 2025 annual meeting with a review of the best research and most promising advances in the treatment of inflammatory bowel disease...
Drs Marla Dubinsky, Bruce Sands,...
12/18/2025
Advances in Inflammatory Bowel Disease Network
Phillip Fleshner
Conference Coverage
12/18/2025
Rebecca Mashaw
In his address to the Advances in IBD annual meeting, Dr Phillip Fleshner stressed the importance of early involvement of the surgeon in collaborative patient care and that the need for surgery should not be viewed as a failure of medical...
In his address to the Advances in IBD annual meeting, Dr Phillip Fleshner stressed the importance of early involvement of the surgeon in collaborative patient care and that the need for surgery should not be viewed as a failure of medical...
In his address to the Advances...
12/18/2025
Advances in Inflammatory Bowel Disease Network
Ray Cross
Conference Coverage
12/17/2025
Jessica Garlewicz
Dr Raymond Cross emphasized the importance of identifying risk early and aligning therapy with both clinical severity and patient-specific needs as IBD moves toward precision medicine.
Dr Raymond Cross emphasized the importance of identifying risk early and aligning therapy with both clinical severity and patient-specific needs as IBD moves toward precision medicine.
Dr Raymond Cross emphasized the...
12/17/2025
Advances in Inflammatory Bowel Disease Network