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Extraintestinal Manifestations Topic Center

Featured Content

Research Highlights
10/17/2025
Rebecca Mashaw
A 2-decade Israeli cohort study reveals stable but clinically significant rates of ocular complications in adults newly diagnosed with inflammatory bowel disease.
A 2-decade Israeli cohort study reveals stable but clinically significant rates of ocular complications in adults newly diagnosed with inflammatory bowel disease.
A 2-decade Israeli cohort study...
10/17/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
08/26/2025
Riya Gandhi, MA
A nationwide cohort analysis from Sweden reveals a 48% increased risk of interstitial lung disease among patients with inflammatory bowel disease, with ulcerative colitis and Crohn’s disease both contributing to elevated rates.
A nationwide cohort analysis from Sweden reveals a 48% increased risk of interstitial lung disease among patients with inflammatory bowel disease, with ulcerative colitis and Crohn’s disease both contributing to elevated rates.
A nationwide cohort analysis...
08/26/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
08/11/2025
Jessica Garlewicz
Integrating brief questionnaires like IBIS-Q into clinic workflows may facilitate earlier SpA recognition, improve interdisciplinary care coordination, and ultimately enhance long-term outcomes for patients with IBD.
Integrating brief questionnaires like IBIS-Q into clinic workflows may facilitate earlier SpA recognition, improve interdisciplinary care coordination, and ultimately enhance long-term outcomes for patients with IBD.
Integrating brief questionnaires...
08/11/2025
Advances in Inflammatory Bowel Disease Network
News
12/05/2024
Riya Gandhi, MA
A large cohort study reveals key factors linked to multiple extraintestinal manifestations in inflammatory bowel disease, offering new insights into personalized treatment approaches.
A large cohort study reveals key factors linked to multiple extraintestinal manifestations in inflammatory bowel disease, offering new insights into personalized treatment approaches.
A large cohort study reveals key...
12/05/2024
Advances in Inflammatory Bowel Disease Network
Dermot McGovern
Podcast
06/19/2024
Dr McGovern discusses the results of a study he and colleagues conducted into the genetic and serological associations of extraintestinal manifestations among patients with inflammatory bowel disease.
Dr McGovern discusses the results of a study he and colleagues conducted into the genetic and serological associations of extraintestinal manifestations among patients with inflammatory bowel disease.
Dr McGovern discusses the...
06/19/2024
Advances in Inflammatory Bowel Disease Network

News

Research Highlights
08/11/2025
Jessica Garlewicz
Integrating brief questionnaires like IBIS-Q into clinic workflows may facilitate earlier SpA recognition, improve interdisciplinary care coordination, and ultimately enhance long-term outcomes for patients with IBD.
Integrating brief questionnaires like IBIS-Q into clinic workflows may facilitate earlier SpA recognition, improve interdisciplinary care coordination, and ultimately enhance long-term outcomes for patients with IBD.
Integrating brief questionnaires...
08/11/2025
Advances in Inflammatory Bowel Disease Network
News
12/05/2024
Riya Gandhi, MA
A large cohort study reveals key factors linked to multiple extraintestinal manifestations in inflammatory bowel disease, offering new insights into personalized treatment approaches.
A large cohort study reveals key factors linked to multiple extraintestinal manifestations in inflammatory bowel disease, offering new insights into personalized treatment approaches.
A large cohort study reveals key...
12/05/2024
Advances in Inflammatory Bowel Disease Network
Research Review
02/03/2026
Rebecca Mashaw
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from more than 1.5 million individuals, providing the most extensive evidence yet on MASLD’s prevalence and associated factors in patients with Crohn’s disease and ulcerative colitis.
The study draws on data from...
02/03/2026
Gastroenterology
News
11/06/2025
Rebecca Mashaw
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said...
11/06/2025
Advances in Inflammatory Bowel Disease Network
FDA alert
FDA Alert
10/14/2025
Rebecca Mashaw
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for upadacitinib therapy among patients who have received any approved systemic therapy for IBD “in the event TNF blockers are clinically inadvisable."
The new indication allows for...
10/14/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
09/18/2025
Jessica Garlewicz
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that most baseline concomitant therapies do not require modification or exclusion when initiating advanced therapy in clinical trial settings.
New study findings suggest that...
09/18/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
09/04/2025
Rebecca Mashaw
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with acute severe ulcerative colitis remain at elevated thrombotic risk for up to 12 weeks post-hospitalization.
New findings show patients with...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
09/04/2025
Rebecca Mashaw
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing Crohn’s disease achieved higher rates of fistula resolution and clinical response with upadacitinib versus placebo.
Patients with fistulizing...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
09/04/2025
Jessica Garlewicz
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a diagnostic blind spot in pediatric CD management and supports adding baseline pelvic MRI to initial workup, even in the absence of perianal symptoms.
The study highlights a...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
09/04/2025
Jessica Garlewicz
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight mirikizumab as a therapeutic option that delivers not only symptom relief but also sustained improvements in quality of life and functional outcomes for patients with moderate to severe CD.
Study findings highlight...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
09/04/2025
Jessica Garlewicz
Risankizumab led to earlier and sustained improvements in individual symptoms—including abdominal pain, bowel urgency, fecal incontinence, and sleep interruption
Risankizumab led to earlier and sustained improvements in individual symptoms—including abdominal pain, bowel urgency, fecal incontinence, and sleep interruption
Risankizumab led to earlier and...
09/04/2025
Advances in Inflammatory Bowel Disease Network
Research Highlights
09/04/2025
Jessica Garlewicz
The study met all primary and multiplicity-controlled secondary endpoints, including clinical and endoscopic outcomes through 48 weeks.
The study met all primary and multiplicity-controlled secondary endpoints, including clinical and endoscopic outcomes through 48 weeks.
The study met all primary and...
09/04/2025
Advances in Inflammatory Bowel Disease Network

Expert Insights

Conference Coverage
01/24/2026
Dr Cates describes her award-winning poster on the use of anal pap smears to identify patients at high risk of developing anal cancer and advance them to high-resolution anometry.
Dr Cates describes her award-winning poster on the use of anal pap smears to identify patients at high risk of developing anal cancer and advance them to high-resolution anometry.
Dr Cates describes her...
01/24/2026
Advances in Inflammatory Bowel Disease Network
Conference Coverage
01/24/2026
Dana Neugut, MD
Dr Neugut reviews her award-winning poster from AIBD on the association of Childhood Opportunity Index with time to infliximab discontinuation in pediatric patients with inflammatory bowel disease.
Dr Neugut reviews her award-winning poster from AIBD on the association of Childhood Opportunity Index with time to infliximab discontinuation in pediatric patients with inflammatory bowel disease.
Dr Neugut reviews her...
01/24/2026
Advances in Inflammatory Bowel Disease Network
Conference Coverage
01/20/2026
Ece Unal, MD
Cleveland Clinic surgery resident Ece Unal, MD, gives an overview of her award-winning poster on a systematic review of excision of skin tags in perianal Crohn’s Disease, presented at the AIBD Annual Meeting.
Cleveland Clinic surgery resident Ece Unal, MD, gives an overview of her award-winning poster on a systematic review of excision of skin tags in perianal Crohn’s Disease, presented at the AIBD Annual Meeting.
Cleveland Clinic surgery...
01/20/2026
Advances in Inflammatory Bowel Disease Network
From the AIBD Open Air Studio
01/20/2026
Wei Wei Lee, MD
Dr Lee describes her award-winning poster presentation on the frequency of changes in diagnosis from ulcerative colitis to Crohn's disease among pediatric patients.
Dr Lee describes her award-winning poster presentation on the frequency of changes in diagnosis from ulcerative colitis to Crohn's disease among pediatric patients.
Dr Lee describes her...
01/20/2026
Advances in Inflammatory Bowel Disease Network
IBD Drive time logo
Expert Insights
01/13/2026
Raymond Cross, MD; Sara Horst, MD
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive Time, Dr Raymond Cross switches seats and acts as the guest with Sara Horst, MD, as host, to discuss the complexities of ostomy complications.
In this episode of IBD Drive...
01/13/2026
Advances in Inflammatory Bowel Disease Network
Oriana Damas
From the AIBD Open Air Studio
12/29/2025
Oriana Damas, MD, MSCTI
Awarded the Sherman Emerging Leader Prize at the Advances in IBD annual meeting, Dr Oriana Damas encouraged others to use passion, dedication, and vision to move the field forward.
Awarded the Sherman Emerging Leader Prize at the Advances in IBD annual meeting, Dr Oriana Damas encouraged others to use passion, dedication, and vision to move the field forward.
Awarded the Sherman Emerging...
12/29/2025
Advances in Inflammatory Bowel Disease Network
Michael Kappelman
From the AIBD Open Air Studio
12/29/2025
Michael Kappelman, MD
Dr Michael Kappelman, one of the Sherman Prize winners for 2025, speaks from the Open Air Studio at the Advances in IBD meeting about his clinical and research work with pediatric patients with ulcerative colitis or Crohn's disease.
Dr Michael Kappelman, one of the Sherman Prize winners for 2025, speaks from the Open Air Studio at the Advances in IBD meeting about his clinical and research work with pediatric patients with ulcerative colitis or Crohn's disease.
Dr Michael Kappelman, one of the...
12/29/2025
Advances in Inflammatory Bowel Disease Network
Scott Snapper
From the AIBD Open Air Studio
12/29/2025
Scott Snapper, MD
Sherman Prize winner Dr Scott Snapper reviewed his team's work on the genetics associated with IBD in children from the Open Air Studio at the Advances in IBD annual meeting.
Sherman Prize winner Dr Scott Snapper reviewed his team's work on the genetics associated with IBD in children from the Open Air Studio at the Advances in IBD annual meeting.
Sherman Prize winner Dr Scott...
12/29/2025
Advances in Inflammatory Bowel Disease Network
Corey & Miguel
From the AIBD Open Air Studio
12/23/2025
Miguel D. Regueiro, MD; Corey A. Siegel, MD, MS
For the 9th year, Drs Miguel Regueiro and Corey Siegel both claim victory in their annual debate—this time, about switching vs optimizing therapies—and remain friends.
For the 9th year, Drs Miguel Regueiro and Corey Siegel both claim victory in their annual debate—this time, about switching vs optimizing therapies—and remain friends.
For the 9th year, Drs Miguel...
12/23/2025
Advances in Inflammatory Bowel Disease Network
Ray Cross and Tina Ha
From the AIBD Open Air Studio
12/23/2025
Raymond Cross, MD; Christina Ha, MD
In the first-ever video version of the IBD Drive Time podcast, Drs Raymond Cross and Christina Ha discuss positioning IBD therapies from our Open Air Studio at the AIBD Annual Meeting.
In the first-ever video version of the IBD Drive Time podcast, Drs Raymond Cross and Christina Ha discuss positioning IBD therapies from our Open Air Studio at the AIBD Annual Meeting.
In the first-ever video version...
12/23/2025
Advances in Inflammatory Bowel Disease Network

Interactive Features

Quiz
08/07/2025
Rebecca Mashaw
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in patients with Crohn’s disease associated with colorectal cancer risk? See what recent research found by taking our quiz.
Is terminal ileum resection in...
08/07/2025
Gastroenterology
Quiz
07/18/2025
Can hormone replacement therapy help or harm disease activity among women with IBD? Our quiz will show the answer!
Can hormone replacement therapy help or harm disease activity among women with IBD? Our quiz will show the answer!
Can hormone replacement therapy...
07/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/18/2025
Can a wearable sensor help monitor disease activity in IBD--via sweat? Take our quiz to get the answer.
Can a wearable sensor help monitor disease activity in IBD--via sweat? Take our quiz to get the answer.
Can a wearable sensor help...
07/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/01/2025
Rebecca Mashaw
Which of the following factors did clinicians say in a recent study is particularly important for EHR functionality in the context of IBD?
Which of the following factors did clinicians say in a recent study is particularly important for EHR functionality in the context of IBD?
Which of the following factors...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/01/2025
Rebecca Mashaw
According to a recent survey of clinicians who care for patients with inflammatory bowel disease, what percentage reported that their EHR system does not enhance patient care in IBD?
According to a recent survey of clinicians who care for patients with inflammatory bowel disease, what percentage reported that their EHR system does not enhance patient care in IBD?
According to a recent survey of...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
07/01/2025
Rebecca Mashaw
A multicenter Canadian study to evaluate advanced combination treatment (ACT) in patients with refractory inflammatory bowel disease (IBD) arrived at which of the following conclusions?
A multicenter Canadian study to evaluate advanced combination treatment (ACT) in patients with refractory inflammatory bowel disease (IBD) arrived at which of the following conclusions?
A multicenter Canadian study to...
07/01/2025
Advances in Inflammatory Bowel Disease Network
Quiz
05/22/2025
Rebecca Mashaw
Does hormone replacement therapy have any effect on treatment for IBD among postmenopausal women? Take our quiz to find out!
Does hormone replacement therapy have any effect on treatment for IBD among postmenopausal women? Take our quiz to find out!
Does hormone replacement therapy...
05/22/2025
Advances in Inflammatory Bowel Disease Network
Quiz
03/18/2025
Rebecca Mashaw
How much do you know about upper GI Crohn's disease? Take our quiz to check your knowledge!
How much do you know about upper GI Crohn's disease? Take our quiz to check your knowledge!
How much do you know about upper...
03/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
03/18/2025
Rebecca Mashaw
What is one benefit of preoperative exclusive enteral nutrition for Crohn’s disease patients? Take our quiz to find out if you know the answer!
What is one benefit of preoperative exclusive enteral nutrition for Crohn’s disease patients? Take our quiz to find out if you know the answer!
What is one benefit of...
03/18/2025
Advances in Inflammatory Bowel Disease Network
Quiz
02/26/2025
Rebecca Mashaw
Estimates vary but indicate that half or more of patients with Crohn's disease will require surgery at some point in their disease course. Do you know which factors place your patients at high risk for surgery? Take our quiz to find out!
Estimates vary but indicate that half or more of patients with Crohn's disease will require surgery at some point in their disease course. Do you know which factors place your patients at high risk for surgery? Take our quiz to find out!
Estimates vary but indicate that...
02/26/2025
Advances in Inflammatory Bowel Disease Network