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Gout News

Research Highlights
Emerging Microbiome Insights Suggest Novel Adjunct Targets in Gout Management
01/14/2026
Jessica Garlewicz
Growing evidence links alterations in the intestinal microbiome to hyperuricemia and gout, raising interest in whether microbiome-targeted strategies could complement established urate-lowering therapies.
Growing evidence links alterations in the intestinal microbiome to hyperuricemia and gout, raising interest in whether microbiome-targeted strategies could complement established urate-lowering therapies.
Growing evidence links...
01/14/2026
Rheumatology & Arthritis
News
Febuxostat Linked to Higher Hepatotoxicity Risk Than Benzbromarone in Gout Patients
09/15/2025
Riya Gandhi, MA
A propensity score–matched cohort study reveals that febuxostat use carries a significantly higher risk of liver enzyme abnormalities than benzbromarone, particularly among patients with pre-existing liver function elevations.
A propensity score–matched cohort study reveals that febuxostat use carries a significantly higher risk of liver enzyme abnormalities than benzbromarone, particularly among patients with pre-existing liver function elevations.
A propensity score–matched...
09/15/2025
Rheumatology & Arthritis
News
Colchicine Drug Levels Not Predictive of Efficacy or Side Effects in Gout Flare Prevention
09/15/2025
Riya Gandhi, MA
A post hoc analysis of a randomized clinical trial finds no consistent link between plasma colchicine concentrations and flare prevention or adverse effects—challenging the utility of therapeutic drug monitoring in routine gout care.
A post hoc analysis of a randomized clinical trial finds no consistent link between plasma colchicine concentrations and flare prevention or adverse effects—challenging the utility of therapeutic drug monitoring in routine gout care.
A post hoc analysis of a...
09/15/2025
Rheumatology & Arthritis
Research Highlights
Only One-Third of Gout Flare Patients Follow Up After ED Visit, Study Finds
09/15/2025
Riya Gandhi, MA
New research identifies social and clinical factors—such as marital status, age, and colchicine use—that may influence whether patients seek outpatient care after visiting the emergency department for a gout flare.
New research identifies social and clinical factors—such as marital status, age, and colchicine use—that may influence whether patients seek outpatient care after visiting the emergency department for a gout flare.
New research identifies social...
09/15/2025
Rheumatology & Arthritis
News
Time Trends and Predictors of Gout Remission
09/04/2025
Rebecca Mashaw
Gout remission rates steadily increase to 63% by year 6 on urate-lowering therapy, with odds of remission affected by age, race, comorbidities, disease severity, and choice of treatment.
Gout remission rates steadily increase to 63% by year 6 on urate-lowering therapy, with odds of remission affected by age, race, comorbidities, disease severity, and choice of treatment.
Gout remission rates steadily...
09/04/2025
Rheumatology & Arthritis
News
Treat-to-Target Urate-Lowering Therapy Significantly Improves Quality of Life in Patients With Gout
08/26/2025
Riya Gandhi, MA
A post-hoc analysis of a 72-week randomized trial shows that targeted urate-lowering therapy improves physical function, mobility, and pain in gout patients, with measurable benefits beginning as early as 24 weeks.
A post-hoc analysis of a 72-week randomized trial shows that targeted urate-lowering therapy improves physical function, mobility, and pain in gout patients, with measurable benefits beginning as early as 24 weeks.
A post-hoc analysis of a 72-week...
08/26/2025
Rheumatology & Arthritis
News
Chronic Opioid Use Elevated in Gout Patients, Especially in Underserved Groups
08/26/2025
Riya Gandhi, MA
A large, matched cohort study using U.S. Veterans Health Administration data found that patients with gout are significantly more likely to receive chronic opioid prescriptions than those without gout—particularly among underserved...
A large, matched cohort study using U.S. Veterans Health Administration data found that patients with gout are significantly more likely to receive chronic opioid prescriptions than those without gout—particularly among underserved...
A large, matched cohort study...
08/26/2025
Rheumatology & Arthritis
News
Lignan-Rich Whole Grains Linked to Lower Gout Risk in Large Cohort Study
07/29/2025
Jessica Garlewicz
These results could support plant-based dietary patterns and highlight a potential role for the gut microbiome in modulating gout risk.
These results could support plant-based dietary patterns and highlight a potential role for the gut microbiome in modulating gout risk.
These results could support...
07/29/2025
Rheumatology & Arthritis
News
Monthly Pegloticase Dosing with Methotrexate Shows Promising Efficacy and Safety in Uncontrolled Gout
06/24/2025
Jessica Garlewicz
For rheumatologists, these findings suggest that monthly dosing of pegloticase with MTX may offer a more patient-friendly regimen without compromising therapeutic outcomes, particularly for those with uncontrolled gout requiring long-term...
For rheumatologists, these findings suggest that monthly dosing of pegloticase with MTX may offer a more patient-friendly regimen without compromising therapeutic outcomes, particularly for those with uncontrolled gout requiring long-term...
For rheumatologists, these...
06/24/2025
Rheumatology & Arthritis
Research Highlights
NSAID Prophylaxis Linked to Higher CV Risk Than Colchicine in Gout Patients Starting Allopurinol
06/24/2025
Jessica Garlewicz
Given the known cardiovascular burden among patients with gout, these findings may prompt changes in prophylaxis prescribing practices to prioritize long-term cardiovascular safety.
Given the known cardiovascular burden among patients with gout, these findings may prompt changes in prophylaxis prescribing practices to prioritize long-term cardiovascular safety.
Given the known cardiovascular...
06/24/2025
Rheumatology & Arthritis

Popular Articles

Dr Shari Lipner
Podcast
Could Isolated Nail Psoriasis Predict Psoriatic Arthritis?
03/27/2024
Shari Lipner, MD, PhD
In a cross-sectional study of 36 isolated nail psoriasis patients, 7 of them (19%) went on to develop psoriatic arthritis in the following years. Is there more to this connection between isolated nail psoriasis and early detection of PsA? Dr...
In a cross-sectional study of 36 isolated nail psoriasis patients, 7 of them (19%) went on to develop psoriatic arthritis in the following years. Is there more to this connection between isolated nail psoriasis and early detection of PsA? Dr...
In a cross-sectional study of 36...
03/27/2024
Rheumatology & Arthritis
News
Monitoring axSpA Disease Activity in Clinical Practice
06/14/2024

Rebecca Mashaw, Digital Managing Editor

Rebecca Mashaw, Digital Managing Edit...
A composite measure of disease activity in axial spondyloarthritis that includes extra-articular manifestations could provide more accurate assessments, researchers say.
A composite measure of disease activity in axial spondyloarthritis that includes extra-articular manifestations could provide more accurate assessments, researchers say.
A composite measure of disease...
06/14/2024
Rheumatology & Arthritis
News
Sex, Age Differences Affect Interstitial Lung Disease Subtypes in Rheumatoid Arthritis
10/18/2024
Jessica Garlewicz
Researchers aimed to explore risk factors associated with usual interstitial pneumonia and nonspecific interstitial pneumonia.
Researchers aimed to explore risk factors associated with usual interstitial pneumonia and nonspecific interstitial pneumonia.
Researchers aimed to explore...
10/18/2024
Rheumatology & Arthritis
News
Antiobesity Medication, Weight Loss, and Mortality Among OA Patients
02/08/2024
Rebecca Mashaw
Researchers investigated whether using antiobesity medications, and the pace of weight loss, reduced mortality among patients with overweight or obesity and knee or hip osteoarthritis.
Researchers investigated whether using antiobesity medications, and the pace of weight loss, reduced mortality among patients with overweight or obesity and knee or hip osteoarthritis.
Researchers investigated whether...
02/08/2024
Rheumatology & Arthritis
News
Disease Activity, Physical Function Associated With Worse Quality of Life in axSpA
08/06/2024
Rebecca Mashaw
Clinical and sociodemographic characteristics are critical in quality of life and functioning, researchers reported.
Clinical and sociodemographic characteristics are critical in quality of life and functioning, researchers reported.
Clinical and sociodemographic...
08/06/2024
Rheumatology & Arthritis

Partner Spotlight

Axial Involvement in SpA: A Patient-Centered Exploration, Chapter 1
SPONSORED
Axial Involvement in SpA, Chapter 1
04/26/2022
Ethan Craig, MD, MPH, discusses 3 of his patient cases to identify and differentiate axial involvement within the spectrum of SpA.
Ethan Craig, MD, MPH, discusses 3 of his patient cases to identify and differentiate axial involvement within the spectrum of SpA.
Ethan Craig, MD, MPH, discusses...
04/26/2022
Rheumatology & Arthritis

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