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Primary Humoral Immunodeficiency Topic Center

Exclusives

News
06/22/2023
Jolynn Tumolo
Multidisciplinary management, including prophylaxis against infection, helps increase the potential for a healthy pregnancy among patients with primary immune deficiencies, researchers say.
Multidisciplinary management, including prophylaxis against infection, helps increase the potential for a healthy pregnancy among patients with primary immune deficiencies, researchers say.
Multidisciplinary management,...
06/22/2023
Rheumatology & Arthritis
laptop with stethoscope
News
06/08/2023
Jolynn Tumolo
Combining electronic health record data such as laboratory tests, radiological orders, and medications provides improved detection of primary immunodeficiency disease, research shows.
Combining electronic health record data such as laboratory tests, radiological orders, and medications provides improved detection of primary immunodeficiency disease, research shows.
Combining electronic health...
06/08/2023
Rheumatology & Arthritis
gastrointestinal
News
05/31/2023
Jolynn Tumolo
Multidisciplinary care of patients with common variable immune deficiency is important in addressing frequent noninfectious gastrointestinal manifestations, researchers say.
Multidisciplinary care of patients with common variable immune deficiency is important in addressing frequent noninfectious gastrointestinal manifestations, researchers say.
Multidisciplinary care of...
05/31/2023
Rheumatology & Arthritis
infection + immunology
News
05/24/2023
Malignancies, allergic reactions, and autoimmune-inflammatory manifestations occur with some frequency among patients with primary immunodeficiency diseases.
Malignancies, allergic reactions, and autoimmune-inflammatory manifestations occur with some frequency among patients with primary immunodeficiency diseases.
Malignancies, allergic...
05/24/2023
Rheumatology & Arthritis
News
03/16/2023
Jolynn Tumolo
Viral infections can be the most significant morbidity in some patients with primary immunodeficiency disease, researchers say.
Viral infections can be the most significant morbidity in some patients with primary immunodeficiency disease, researchers say.
Viral infections can be the most...
03/16/2023
Rheumatology & Arthritis
News
12/11/2022
Better understanding of common cutaneous manifestations among patients with primary immunodeficiencies can enhance timely diagnosis and treatment plans.
Better understanding of common cutaneous manifestations among patients with primary immunodeficiencies can enhance timely diagnosis and treatment plans.
Better understanding of common...
12/11/2022
Rheumatology & Arthritis
News
11/29/2022
Better knowledge of the initial presenting manifestations of primary immunodeficiencies (or inborn errors of immunity) may improve awareness and avoid diagnostic delay.
Better knowledge of the initial presenting manifestations of primary immunodeficiencies (or inborn errors of immunity) may improve awareness and avoid diagnostic delay.
Better knowledge of the initial...
11/29/2022
Rheumatology & Arthritis
News
11/03/2022
Researchers examined whether Nordic score is useful for predicting clinical response among pediatric patients with immune thrombocytopenia.
Researchers examined whether Nordic score is useful for predicting clinical response among pediatric patients with immune thrombocytopenia.
Researchers examined whether...
11/03/2022
Rheumatology & Arthritis
News
10/27/2022
Experts studied the prevalence of fatigue among patients with primary immunodeficiency and investigated the associated factors.
Experts studied the prevalence of fatigue among patients with primary immunodeficiency and investigated the associated factors.
Experts studied the prevalence...
10/27/2022
Rheumatology & Arthritis
News
10/27/2022
Patients who are moderately or severely immunocompromised are encouraged to stay up to date with their COVID-19 and influenza vaccination schedules in order to stay healthy this flu season.
Patients who are moderately or severely immunocompromised are encouraged to stay up to date with their COVID-19 and influenza vaccination schedules in order to stay healthy this flu season.
Patients who are moderately or...
10/27/2022
Rheumatology & Arthritis
News
10/26/2022
Patients diagnosed with immune thrombocytopenia were often found to have comorbid thyroid disease.
Patients diagnosed with immune thrombocytopenia were often found to have comorbid thyroid disease.
Patients diagnosed with immune...
10/26/2022
Rheumatology & Arthritis

News

News
06/22/2023
Jolynn Tumolo
Multidisciplinary management, including prophylaxis against infection, helps increase the potential for a healthy pregnancy among patients with primary immune deficiencies, researchers say.
Multidisciplinary management, including prophylaxis against infection, helps increase the potential for a healthy pregnancy among patients with primary immune deficiencies, researchers say.
Multidisciplinary management,...
06/22/2023
Rheumatology & Arthritis
laptop with stethoscope
News
06/08/2023
Jolynn Tumolo
Combining electronic health record data such as laboratory tests, radiological orders, and medications provides improved detection of primary immunodeficiency disease, research shows.
Combining electronic health record data such as laboratory tests, radiological orders, and medications provides improved detection of primary immunodeficiency disease, research shows.
Combining electronic health...
06/08/2023
Rheumatology & Arthritis
gastrointestinal
News
05/31/2023
Jolynn Tumolo
Multidisciplinary care of patients with common variable immune deficiency is important in addressing frequent noninfectious gastrointestinal manifestations, researchers say.
Multidisciplinary care of patients with common variable immune deficiency is important in addressing frequent noninfectious gastrointestinal manifestations, researchers say.
Multidisciplinary care of...
05/31/2023
Rheumatology & Arthritis
infection + immunology
News
05/24/2023
Malignancies, allergic reactions, and autoimmune-inflammatory manifestations occur with some frequency among patients with primary immunodeficiency diseases.
Malignancies, allergic reactions, and autoimmune-inflammatory manifestations occur with some frequency among patients with primary immunodeficiency diseases.
Malignancies, allergic...
05/24/2023
Rheumatology & Arthritis
News
03/16/2023
Jolynn Tumolo
Viral infections can be the most significant morbidity in some patients with primary immunodeficiency disease, researchers say.
Viral infections can be the most significant morbidity in some patients with primary immunodeficiency disease, researchers say.
Viral infections can be the most...
03/16/2023
Rheumatology & Arthritis
News
01/24/2023
Patients with immunocompromised systems may suffer from severe manifestations from Mpox, warns the latest update from the U.S. Centers for Disease Control and Prevention.
Patients with immunocompromised systems may suffer from severe manifestations from Mpox, warns the latest update from the U.S. Centers for Disease Control and Prevention.
Patients with immunocompromised...
01/24/2023
Rheumatology & Arthritis
News
12/11/2022
Better understanding of common cutaneous manifestations among patients with primary immunodeficiencies can enhance timely diagnosis and treatment plans.
Better understanding of common cutaneous manifestations among patients with primary immunodeficiencies can enhance timely diagnosis and treatment plans.
Better understanding of common...
12/11/2022
Rheumatology & Arthritis
News
11/29/2022
Better knowledge of the initial presenting manifestations of primary immunodeficiencies (or inborn errors of immunity) may improve awareness and avoid diagnostic delay.
Better knowledge of the initial presenting manifestations of primary immunodeficiencies (or inborn errors of immunity) may improve awareness and avoid diagnostic delay.
Better knowledge of the initial...
11/29/2022
Rheumatology & Arthritis
News
11/03/2022
Researchers examined whether Nordic score is useful for predicting clinical response among pediatric patients with immune thrombocytopenia.
Researchers examined whether Nordic score is useful for predicting clinical response among pediatric patients with immune thrombocytopenia.
Researchers examined whether...
11/03/2022
Rheumatology & Arthritis
News
10/27/2022
Experts studied the prevalence of fatigue among patients with primary immunodeficiency and investigated the associated factors.
Experts studied the prevalence of fatigue among patients with primary immunodeficiency and investigated the associated factors.
Experts studied the prevalence...
10/27/2022
Rheumatology & Arthritis
Expert Insights
02/03/2026
Daniel Hal Solomon, MD
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon...
02/03/2026
Rheumatology & Arthritis
Research Highlights
01/14/2026
Jessica Garlewicz
Growing evidence links alterations in the intestinal microbiome to hyperuricemia and gout, raising interest in whether microbiome-targeted strategies could complement established urate-lowering therapies.
Growing evidence links alterations in the intestinal microbiome to hyperuricemia and gout, raising interest in whether microbiome-targeted strategies could complement established urate-lowering therapies.
Growing evidence links...
01/14/2026
Rheumatology & Arthritis
Mark Hwang
Video
11/19/2025
Mark Hwang, MD
Dr Hwang reviews key findings of research he presented at ACR Convergence on inflammatory back pain and the importance of multimodality evaluation to identify patients with axial spondyloarthritis vs mechanical back pain.
Dr Hwang reviews key findings of research he presented at ACR Convergence on inflammatory back pain and the importance of multimodality evaluation to identify patients with axial spondyloarthritis vs mechanical back pain.
Dr Hwang reviews key findings of...
11/19/2025
Rheumatology & Arthritis
News
11/06/2025
Rebecca Mashaw
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said...
11/06/2025
Rheumatology & Arthritis
Alexis Ogdie
Conference Coverage
11/05/2025
Alexis Ogdie, MD
Dr Ogdie provides updates on new and emerging therapies for psoriatic arthritis, which she presented at the ACR Convergence in Chicago.
Dr Ogdie provides updates on new and emerging therapies for psoriatic arthritis, which she presented at the ACR Convergence in Chicago.
Dr Ogdie provides updates on new...
11/05/2025
Rheumatology & Arthritis
Laura Coates
Conference Coverage
11/03/2025
Laura Coates, MBChB
Dr Coates discusses her presentation at ACR Convergence on a study that found the risk of developing psoriatic arthritis was lowest among patients with psoriasis who were treated with IL-17 inhibitors compared to those treated with IL-23,...
Dr Coates discusses her presentation at ACR Convergence on a study that found the risk of developing psoriatic arthritis was lowest among patients with psoriasis who were treated with IL-17 inhibitors compared to those treated with IL-23,...
Dr Coates discusses her...
11/03/2025
Rheumatology & Arthritis
Conference Coverage
10/31/2025
Riya Gandhi, MA
A large national study of U.S. veterans presented at ACR Convergence reveals that PTSD increases the risk of RA, especially in never-smokers, suggesting distinct immune mechanisms may drive disease in different exposure subgroups.
A large national study of U.S. veterans presented at ACR Convergence reveals that PTSD increases the risk of RA, especially in never-smokers, suggesting distinct immune mechanisms may drive disease in different exposure subgroups.
A large national study of U.S....
10/31/2025
Rheumatology & Arthritis
Conference Coverage
10/31/2025
Riya Gandhi, MA
Over 70% of rheumatoid arthritis patients who screen positive for anxiety, depression, or fibromyalgia report memory, sleep, or fatigue problems, highlighting the value of symptom checklists in noninflammatory disease assessment.
Over 70% of rheumatoid arthritis patients who screen positive for anxiety, depression, or fibromyalgia report memory, sleep, or fatigue problems, highlighting the value of symptom checklists in noninflammatory disease assessment.
Over 70% of rheumatoid arthritis...
10/31/2025
Rheumatology & Arthritis
Conference Coverage
10/31/2025
Riya Gandhi, MA
A targeted workflow intervention involving pharmacists and coordinated care increased recombinant zoster vaccine uptake from 10% to over 15% among RA patients under 50—surpassing institutional goals and highlighting scalable strategies to...
A targeted workflow intervention involving pharmacists and coordinated care increased recombinant zoster vaccine uptake from 10% to over 15% among RA patients under 50—surpassing institutional goals and highlighting scalable strategies to...
A targeted workflow intervention...
10/31/2025
Rheumatology & Arthritis
Conference Coverage
10/31/2025
Riya Gandhi, MA
Early data from the ERIN registry reveal diverse rheumatic immune-related adverse events (rh-irAEs), with RA-like polyarthritis and age-specific SpA phenotypes dominating presentations—highlighting the need for tailored management approaches.
Early data from the ERIN registry reveal diverse rheumatic immune-related adverse events (rh-irAEs), with RA-like polyarthritis and age-specific SpA phenotypes dominating presentations—highlighting the need for tailored management approaches.
Early data from the ERIN...
10/31/2025
Rheumatology & Arthritis

Interactive Features

Quiz
08/07/2025
Rebecca Mashaw
Do men or women achieve better outcomes with advanced therapies for axial spondyloarthritis? Find out by taking our quick quiz.
Do men or women achieve better outcomes with advanced therapies for axial spondyloarthritis? Find out by taking our quick quiz.
Do men or women achieve better...
08/07/2025
Rheumatology & Arthritis
Quiz
08/07/2025
Rebecca Mashaw
One factor showed a substantial association with mortality among patients with rheumatoid arthritis. Find out what it is with our quiz!
One factor showed a substantial association with mortality among patients with rheumatoid arthritis. Find out what it is with our quiz!
One factor showed a substantial...
08/07/2025
Rheumatology & Arthritis
Quiz
07/21/2025
Rebecca Mashaw
07/21/2025
Rheumatology & Arthritis
Quiz
08/30/2024
Riya Gandhi, MA
Is there any association between nonsteroidal anti-inflammatory drugs (NSAIDs), axial spondyloarthritis (axSpA), and risk of cardiovascular disease (CVD)?a) No, there is no evidence that NSAID use increases the risk of CVD on patients with...
Is there any association between nonsteroidal anti-inflammatory drugs (NSAIDs), axial spondyloarthritis (axSpA), and risk of cardiovascular disease (CVD)?a) No, there is no evidence that NSAID use increases the risk of CVD on patients with...
Is there any association between...
08/30/2024
Rheumatology & Arthritis
Quiz
08/07/2024
Rebecca Mashaw
What demographic characteristics are typical of patients with axial spondyloarthritis? Learn more when you take our quick quiz!
What demographic characteristics are typical of patients with axial spondyloarthritis? Learn more when you take our quick quiz!
What demographic characteristics...
08/07/2024
Rheumatology & Arthritis
Quiz
03/14/2024

Priyam Vora, Associate Editor

Priyam Vora, Associate Editor
Is obesity a risk and severity factor among patients with rheumatic conditions? Or does weight have no bearing on autoimmune disorders? Find out with one quick question!
Is obesity a risk and severity factor among patients with rheumatic conditions? Or does weight have no bearing on autoimmune disorders? Find out with one quick question!
Is obesity a risk and severity...
03/14/2024
Rheumatology & Arthritis
Quiz
02/22/2024
Priyam Vora
Researchers developed the Psoriatic Arthritis Risk Estimation Tool (PRESTO) to predict the 1- and 5-year risk of developing psoriatic arthritis in patients with psoriasis. Take our quiz to test your knowledge on the subject!
Researchers developed the Psoriatic Arthritis Risk Estimation Tool (PRESTO) to predict the 1- and 5-year risk of developing psoriatic arthritis in patients with psoriasis. Take our quiz to test your knowledge on the subject!
Researchers developed the...
02/22/2024
Rheumatology & Arthritis
Quiz
02/06/2024
Priyam Vora
Take a quick quiz to test your knowledge on gout, a form of arthritis typically characterized by severe pain, redness, and tenderness in joints.
Take a quick quiz to test your knowledge on gout, a form of arthritis typically characterized by severe pain, redness, and tenderness in joints.
Take a quick quiz to test your...
02/06/2024
Rheumatology & Arthritis
spinal xray
Quiz
02/01/2024
A retrospective cohort study identified 1426 adults with prevalent ankylosing spondylitis. Do you know the characteristic with the highest odds ratio to fractures among these patients? Take our quiz to test your knowledge!
A retrospective cohort study identified 1426 adults with prevalent ankylosing spondylitis. Do you know the characteristic with the highest odds ratio to fractures among these patients? Take our quiz to test your knowledge!
A retrospective cohort study...
02/01/2024
Rheumatology & Arthritis

Podcasts

Expert Insights
02/03/2026
Daniel Hal Solomon, MD
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon...
02/03/2026
Rheumatology & Arthritis
Dacre Knight
Podcast
04/30/2025
Dacre Knight, MD
Dacre Knight, MD, from Mayo Clinic-Florida, provides insights into hypermobility disorders, including Ehlers-Danlos Syndrome, and why they are difficult to diagnose and challenging to treat.
Dacre Knight, MD, from Mayo Clinic-Florida, provides insights into hypermobility disorders, including Ehlers-Danlos Syndrome, and why they are difficult to diagnose and challenging to treat.
Dacre Knight, MD, from Mayo...
04/30/2025
Rheumatology & Arthritis
Len Calabrese
Podcast
01/02/2025
Leonard Calabrese, DO
Dr Calabrese discusses the similarities between long COVID, fibromyalgia, and in its most severe form, myalgic encephalomyelitis/chronic fatigue syndrome, and the importance of reassuring patients that their symptoms and conditions are real.
Dr Calabrese discusses the similarities between long COVID, fibromyalgia, and in its most severe form, myalgic encephalomyelitis/chronic fatigue syndrome, and the importance of reassuring patients that their symptoms and conditions are real.
Dr Calabrese discusses the...
01/02/2025
Rheumatology & Arthritis
Misti Paudel
Podcast
08/12/2024
Dr Paudel reviews research she and colleagues conducted to validate the EULAR definition of difficult-to-treat rheumatoid arthritis, and differences among patients with difficult-to-treat RA versus those with controlled disease.
Dr Paudel reviews research she and colleagues conducted to validate the EULAR definition of difficult-to-treat rheumatoid arthritis, and differences among patients with difficult-to-treat RA versus those with controlled disease.
Dr Paudel reviews research she...
08/12/2024
Rheumatology & Arthritis
Vikas Majithia
Podcast
06/20/2024
Drs Majithia and Butendieck provide some perspective on the continuing issues surrounding the diagnosis and effective treatment of gout, the most common inflammatory arthritis in the US.
Drs Majithia and Butendieck provide some perspective on the continuing issues surrounding the diagnosis and effective treatment of gout, the most common inflammatory arthritis in the US.
Drs Majithia and Butendieck...
06/20/2024
Rheumatology & Arthritis
Podcast
04/08/2024
In this podcast, Drs England and Smith discuss the key recommendations and how to implement exercise, rehabilitation, diet, and additional interventions as part of an integrative management approach for people with rheumatoid arthritis.
In this podcast, Drs England and Smith discuss the key recommendations and how to implement exercise, rehabilitation, diet, and additional interventions as part of an integrative management approach for people with rheumatoid arthritis.
In this podcast, Drs England and...
04/08/2024
Rheumatology & Arthritis
Dr Shari Lipner
Podcast
03/27/2024
Shari Lipner, MD, PhD
In a cross-sectional study of 36 isolated nail psoriasis patients, 7 of them (19%) went on to develop psoriatic arthritis in the following years. Is there more to this connection between isolated nail psoriasis and early detection of PsA? Dr...
In a cross-sectional study of 36 isolated nail psoriasis patients, 7 of them (19%) went on to develop psoriatic arthritis in the following years. Is there more to this connection between isolated nail psoriasis and early detection of PsA? Dr...
In a cross-sectional study of 36...
03/27/2024
Rheumatology & Arthritis
Jeff Sparks
Podcast
03/14/2024
Dr Jeffrey Sparks and research assistant Emily Kowalski from Brigham & Women's Hospital in Boston share their findings from a study of the risk factors found among patient with systemic rheumatic diseases for repeat infections with COVID-19.
Dr Jeffrey Sparks and research assistant Emily Kowalski from Brigham & Women's Hospital in Boston share their findings from a study of the risk factors found among patient with systemic rheumatic diseases for repeat infections with COVID-19.
Dr Jeffrey Sparks and research...
03/14/2024
Rheumatology & Arthritis
Neal Birnbam
Podcast
03/08/2024
Dr Birnbaum comments on how the new rule from the Centers for Medicare & Medicaid Services setting tighter timelines for health insurers to act on requests for authorization for medications and procedures.
Dr Birnbaum comments on how the new rule from the Centers for Medicare & Medicaid Services setting tighter timelines for health insurers to act on requests for authorization for medications and procedures.
Dr Birnbaum comments on how the...
03/08/2024
Rheumatology & Arthritis
Len Calabrese
Podcast
02/29/2024
Dr Leonard Calabrese of the Cleveland Clinic discusses the similarities and differences of fibromyalgia, chronic fatigue syndrome, and long COVID, and why classifying these diseases properly is important to diagnosis and treatment.
Dr Leonard Calabrese of the Cleveland Clinic discusses the similarities and differences of fibromyalgia, chronic fatigue syndrome, and long COVID, and why classifying these diseases properly is important to diagnosis and treatment.
Dr Leonard Calabrese of the...
02/29/2024
Rheumatology & Arthritis