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Gout Topic Center

Featured

Expert Insights
02/03/2026
Daniel Hal Solomon, MD
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon...
02/03/2026
Rheumatology & Arthritis
Research Highlights
01/14/2026
Jessica Garlewicz
Growing evidence links alterations in the intestinal microbiome to hyperuricemia and gout, raising interest in whether microbiome-targeted strategies could complement established urate-lowering therapies.
Growing evidence links alterations in the intestinal microbiome to hyperuricemia and gout, raising interest in whether microbiome-targeted strategies could complement established urate-lowering therapies.
Growing evidence links...
01/14/2026
Rheumatology & Arthritis
News
09/15/2025
Riya Gandhi, MA
A propensity score–matched cohort study reveals that febuxostat use carries a significantly higher risk of liver enzyme abnormalities than benzbromarone, particularly among patients with pre-existing liver function elevations.
A propensity score–matched cohort study reveals that febuxostat use carries a significantly higher risk of liver enzyme abnormalities than benzbromarone, particularly among patients with pre-existing liver function elevations.
A propensity score–matched...
09/15/2025
Rheumatology & Arthritis
News
09/15/2025
Riya Gandhi, MA
A post hoc analysis of a randomized clinical trial finds no consistent link between plasma colchicine concentrations and flare prevention or adverse effects—challenging the utility of therapeutic drug monitoring in routine gout care.
A post hoc analysis of a randomized clinical trial finds no consistent link between plasma colchicine concentrations and flare prevention or adverse effects—challenging the utility of therapeutic drug monitoring in routine gout care.
A post hoc analysis of a...
09/15/2025
Rheumatology & Arthritis
Research Highlights
09/15/2025
Riya Gandhi, MA
New research identifies social and clinical factors—such as marital status, age, and colchicine use—that may influence whether patients seek outpatient care after visiting the emergency department for a gout flare.
New research identifies social and clinical factors—such as marital status, age, and colchicine use—that may influence whether patients seek outpatient care after visiting the emergency department for a gout flare.
New research identifies social...
09/15/2025
Rheumatology & Arthritis
News
08/26/2025
Riya Gandhi, MA
A post-hoc analysis of a 72-week randomized trial shows that targeted urate-lowering therapy improves physical function, mobility, and pain in gout patients, with measurable benefits beginning as early as 24 weeks.
A post-hoc analysis of a 72-week randomized trial shows that targeted urate-lowering therapy improves physical function, mobility, and pain in gout patients, with measurable benefits beginning as early as 24 weeks.
A post-hoc analysis of a 72-week...
08/26/2025
Rheumatology & Arthritis
News
08/26/2025
Riya Gandhi, MA
A large, matched cohort study using U.S. Veterans Health Administration data found that patients with gout are significantly more likely to receive chronic opioid prescriptions than those without gout—particularly among underserved...
A large, matched cohort study using U.S. Veterans Health Administration data found that patients with gout are significantly more likely to receive chronic opioid prescriptions than those without gout—particularly among underserved...
A large, matched cohort study...
08/26/2025
Rheumatology & Arthritis
News
06/18/2025
Rebecca Mashaw
A Phase 4 trial showed monthly rather than biweekly pegloticase infusions could improve patient adherence and still maintain control of gout.
A Phase 4 trial showed monthly rather than biweekly pegloticase infusions could improve patient adherence and still maintain control of gout.
A Phase 4 trial showed monthly...
06/18/2025
Rheumatology & Arthritis
News
06/10/2025
Rebecca Mashaw
Researchers found that patients’ perception of gout flare symptoms are reliable indicators of flare frequency.
Researchers found that patients’ perception of gout flare symptoms are reliable indicators of flare frequency.
Researchers found that patients’...
06/10/2025
Rheumatology & Arthritis
News
05/08/2025
Rebecca Mashaw
Findings of a new study encourage optimizing ULT for patients with gout and chronic kidney disease without fear of worsening kidney outcomes.
Findings of a new study encourage optimizing ULT for patients with gout and chronic kidney disease without fear of worsening kidney outcomes.
Findings of a new study...
05/08/2025
Rheumatology & Arthritis
News
03/13/2025
Anthony Calabro, MA
Gout flare prophylaxis with colchicine was associated with a lower rate of cardiovascular events for up to the next 180 days compared with no prophylaxis.
Gout flare prophylaxis with colchicine was associated with a lower rate of cardiovascular events for up to the next 180 days compared with no prophylaxis.
Gout flare prophylaxis with...
03/13/2025
Rheumatology & Arthritis

Insights

Expert Insights
02/03/2026
Daniel Hal Solomon, MD
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon...
02/03/2026
Rheumatology & Arthritis
RHEUMATOLOGY
08/05/2019
Dr Solomon discusses what rheumatologists should know about interleukin-1β inhibitors, his research on the relationship between the inhibitors and gout, and more.
Dr Solomon discusses what rheumatologists should know about interleukin-1β inhibitors, his research on the relationship between the inhibitors and gout, and more.
Dr Solomon discusses what...
08/05/2019
Rheumatology & Arthritis
Expert Insights
02/03/2026
Daniel Hal Solomon, MD
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon reviews the design of, recruitment for, and established outcomes of the TRUST trial, a randomized controlled active comparator strategy for gout to compare a treat to target serum urate strategy versus an approach...
In this podcast, Dr Solomon...
02/03/2026
Rheumatology & Arthritis
Mark Hwang
Video
11/19/2025
Mark Hwang, MD
Dr Hwang reviews key findings of research he presented at ACR Convergence on inflammatory back pain and the importance of multimodality evaluation to identify patients with axial spondyloarthritis vs mechanical back pain.
Dr Hwang reviews key findings of research he presented at ACR Convergence on inflammatory back pain and the importance of multimodality evaluation to identify patients with axial spondyloarthritis vs mechanical back pain.
Dr Hwang reviews key findings of...
11/19/2025
Rheumatology & Arthritis
Alexis Ogdie
Conference Coverage
11/05/2025
Alexis Ogdie, MD
Dr Ogdie provides updates on new and emerging therapies for psoriatic arthritis, which she presented at the ACR Convergence in Chicago.
Dr Ogdie provides updates on new and emerging therapies for psoriatic arthritis, which she presented at the ACR Convergence in Chicago.
Dr Ogdie provides updates on new...
11/05/2025
Rheumatology & Arthritis
Laura Coates
Conference Coverage
11/03/2025
Laura Coates, MBChB
Dr Coates discusses her presentation at ACR Convergence on a study that found the risk of developing psoriatic arthritis was lowest among patients with psoriasis who were treated with IL-17 inhibitors compared to those treated with IL-23,...
Dr Coates discusses her presentation at ACR Convergence on a study that found the risk of developing psoriatic arthritis was lowest among patients with psoriasis who were treated with IL-17 inhibitors compared to those treated with IL-23,...
Dr Coates discusses her...
11/03/2025
Rheumatology & Arthritis
Sofia Ramiro
Conference Coverage
10/28/2025
Sofia Ramiro, MD
Dr Ramiro reviews her presentation at ACR Convergence on the SPACE cohort study of the difference in structural lesions of the spine as assessed on radiographs and on MRI between patients with early axial SPA and patients with nonaxial SpA...
Dr Ramiro reviews her presentation at ACR Convergence on the SPACE cohort study of the difference in structural lesions of the spine as assessed on radiographs and on MRI between patients with early axial SPA and patients with nonaxial SpA...
Dr Ramiro reviews her...
10/28/2025
Rheumatology & Arthritis
Paras Karmacharya
Conference Coverage
10/28/2025
Paras Karmacharya, MD
Dr Karmacharya reviews his presentation from ACR Convergence a population-based study from the UK THIN database across psoriatic arthritis, psoriasis, and axial spondyloarthritis to find distinct and remarkably stable patterns of...
Dr Karmacharya reviews his presentation from ACR Convergence a population-based study from the UK THIN database across psoriatic arthritis, psoriasis, and axial spondyloarthritis to find distinct and remarkably stable patterns of...
Dr Karmacharya reviews his...
10/28/2025
Rheumatology & Arthritis
Dacre Knight
Podcast
04/30/2025
Dacre Knight, MD
Dacre Knight, MD, from Mayo Clinic-Florida, provides insights into hypermobility disorders, including Ehlers-Danlos Syndrome, and why they are difficult to diagnose and challenging to treat.
Dacre Knight, MD, from Mayo Clinic-Florida, provides insights into hypermobility disorders, including Ehlers-Danlos Syndrome, and why they are difficult to diagnose and challenging to treat.
Dacre Knight, MD, from Mayo...
04/30/2025
Rheumatology & Arthritis
Al Kim
Video
01/31/2025
Alfred Kim, MD, PhD
Dr Kim reviews the the impact of poor sleep and circadian dysfunction on patients with systemic lupus erythematosus.
Dr Kim reviews the the impact of poor sleep and circadian dysfunction on patients with systemic lupus erythematosus.
Dr Kim reviews the the impact of...
01/31/2025
Rheumatology & Arthritis
Len Calabrese
Podcast
01/02/2025
Leonard Calabrese, DO
Dr Calabrese discusses the similarities between long COVID, fibromyalgia, and in its most severe form, myalgic encephalomyelitis/chronic fatigue syndrome, and the importance of reassuring patients that their symptoms and conditions are real.
Dr Calabrese discusses the similarities between long COVID, fibromyalgia, and in its most severe form, myalgic encephalomyelitis/chronic fatigue syndrome, and the importance of reassuring patients that their symptoms and conditions are real.
Dr Calabrese discusses the...
01/02/2025
Rheumatology & Arthritis
Bryant England
Video
12/06/2024
Bryant England, MD
Dr England recaps his presentation on interstitial lung disease among patients with rheumatoid arthritis, including the importance of early detection and how to diagnose this condition,
Dr England recaps his presentation on interstitial lung disease among patients with rheumatoid arthritis, including the importance of early detection and how to diagnose this condition,
Dr England recaps his...
12/06/2024
Rheumatology & Arthritis

News

News
06/18/2025
Rebecca Mashaw
A Phase 4 trial showed monthly rather than biweekly pegloticase infusions could improve patient adherence and still maintain control of gout.
A Phase 4 trial showed monthly rather than biweekly pegloticase infusions could improve patient adherence and still maintain control of gout.
A Phase 4 trial showed monthly...
06/18/2025
Rheumatology & Arthritis
News
06/10/2025
Rebecca Mashaw
Researchers found that patients’ perception of gout flare symptoms are reliable indicators of flare frequency.
Researchers found that patients’ perception of gout flare symptoms are reliable indicators of flare frequency.
Researchers found that patients’...
06/10/2025
Rheumatology & Arthritis
News
05/08/2025
Rebecca Mashaw
Findings of a new study encourage optimizing ULT for patients with gout and chronic kidney disease without fear of worsening kidney outcomes.
Findings of a new study encourage optimizing ULT for patients with gout and chronic kidney disease without fear of worsening kidney outcomes.
Findings of a new study...
05/08/2025
Rheumatology & Arthritis
News
03/13/2025
Anthony Calabro, MA
Gout flare prophylaxis with colchicine was associated with a lower rate of cardiovascular events for up to the next 180 days compared with no prophylaxis.
Gout flare prophylaxis with colchicine was associated with a lower rate of cardiovascular events for up to the next 180 days compared with no prophylaxis.
Gout flare prophylaxis with...
03/13/2025
Rheumatology & Arthritis
News
01/17/2022
Investigators call for more high-quality studies to help reduce hospital admissions for gout.
Investigators call for more high-quality studies to help reduce hospital admissions for gout.
Investigators call for more...
01/17/2022
Rheumatology & Arthritis
News
11/06/2025
Rebecca Mashaw
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said the new lower prices also will be provided for Medicaid programs, with prices and timing decided state by state as they opt in.
Administration officials said...
11/06/2025
Rheumatology & Arthritis
Conference Coverage
10/27/2025
Jessica Garlewicz
Investigators reported at ACR Convergence 2025 that a genome risk score including 5 novel single nucleotide polymorphisms provides significant improvement in discriminating interstitial lung disease among patients with rheumatoid arthritis.
Investigators reported at ACR Convergence 2025 that a genome risk score including 5 novel single nucleotide polymorphisms provides significant improvement in discriminating interstitial lung disease among patients with rheumatoid arthritis.
Investigators reported at ACR...
10/27/2025
Rheumatology & Arthritis
Research Highlights
09/09/2025
Rebecca Mashaw
Structured monitoring and patient-physician collaboration are critical to successful tapering of anti-tumor necrosis factor therapy for patients with psoriatic arthritis or axial spondyloarthritis.
Structured monitoring and patient-physician collaboration are critical to successful tapering of anti-tumor necrosis factor therapy for patients with psoriatic arthritis or axial spondyloarthritis.
Structured monitoring and...
09/09/2025
Rheumatology & Arthritis
News
09/04/2025
Rebecca Mashaw
Gout remission rates steadily increase to 63% by year 6 on urate-lowering therapy, with odds of remission affected by age, race, comorbidities, disease severity, and choice of treatment.
Gout remission rates steadily increase to 63% by year 6 on urate-lowering therapy, with odds of remission affected by age, race, comorbidities, disease severity, and choice of treatment.
Gout remission rates steadily...
09/04/2025
Rheumatology & Arthritis
Research Highlights
08/21/2025
Rebecca Mashaw
Elevated adiponectin and leptin independently and synergistically increase fracture risk in patients with rheumatoid arthritis.
Elevated adiponectin and leptin independently and synergistically increase fracture risk in patients with rheumatoid arthritis.
Elevated adiponectin and leptin...
08/21/2025
Rheumatology & Arthritis
News
08/21/2025
Rebecca Mashaw
Findings of recent study underscore the need for age-aware training and the adoption of frameworks like the Geriatric 5Ms to mitigate age-related disparities in rheumatologic care.
Findings of recent study underscore the need for age-aware training and the adoption of frameworks like the Geriatric 5Ms to mitigate age-related disparities in rheumatologic care.
Findings of recent study...
08/21/2025
Rheumatology & Arthritis
News
08/11/2025
Jessica Garlewicz
Female patients were significantly older and had higher pain scores, while men had higher CRP levels, suggesting potential disparities in disease presentation and inflammation markers.
Female patients were significantly older and had higher pain scores, while men had higher CRP levels, suggesting potential disparities in disease presentation and inflammation markers.
Female patients were...
08/11/2025
Rheumatology & Arthritis
Research Highlights
08/11/2025
Jessica Garlewicz
Integrating brief questionnaires like IBIS-Q into clinic workflows may facilitate earlier SpA recognition, improve interdisciplinary care coordination, and ultimately enhance long-term outcomes for patients with IBD.
Integrating brief questionnaires like IBIS-Q into clinic workflows may facilitate earlier SpA recognition, improve interdisciplinary care coordination, and ultimately enhance long-term outcomes for patients with IBD.
Integrating brief questionnaires...
08/11/2025
Advances in Inflammatory Bowel Disease Network
News
07/29/2025
Jessica Garlewicz
These real-world findings may be of interest to clinicians managing older adults with symptomatic, advanced knee OA who are not candidates for or are delaying surgery.
These real-world findings may be of interest to clinicians managing older adults with symptomatic, advanced knee OA who are not candidates for or are delaying surgery.
These real-world findings may be...
07/29/2025
Rheumatology & Arthritis
News
07/29/2025
Jessica Garlewicz
The results offer practicing rheumatologists a potential new direction for pain management in knee osteoarthritis among patients with metabolic comorbidities.
The results offer practicing rheumatologists a potential new direction for pain management in knee osteoarthritis among patients with metabolic comorbidities.
The results offer practicing...
07/29/2025
Rheumatology & Arthritis

Interactive Feature

Quiz
01/07/2021
Author:  Theodore R. Fields, MD Hospital for Special Surgery Weill Cornell Medical College   A 67-year-old man presents for follow-up of his gout and kidney disease. His mother and brother had...
Author:  Theodore R. Fields, MD Hospital for Special Surgery Weill Cornell Medical College   A 67-year-old man presents for follow-up of his gout and kidney disease. His mother and brother had...
...
01/07/2021
Rheumatology & Arthritis
Quiz
10/24/2018
The use of canakinumab can lower the incidence of gout attacks without changing serum uric acid levels. What is the ideal frequency of canakinumab administration?IncorrectThe correct answer is "Every 3 months."...
The use of canakinumab can lower the incidence of gout attacks without changing serum uric acid levels. What is the ideal frequency of canakinumab administration?IncorrectThe correct answer is "Every 3 months."...
The...
10/24/2018
Rheumatology & Arthritis
Quiz
08/07/2025
Rebecca Mashaw
Do men or women achieve better outcomes with advanced therapies for axial spondyloarthritis? Find out by taking our quick quiz.
Do men or women achieve better outcomes with advanced therapies for axial spondyloarthritis? Find out by taking our quick quiz.
Do men or women achieve better...
08/07/2025
Rheumatology & Arthritis
Quiz
08/07/2025
Rebecca Mashaw
One factor showed a substantial association with mortality among patients with rheumatoid arthritis. Find out what it is with our quiz!
One factor showed a substantial association with mortality among patients with rheumatoid arthritis. Find out what it is with our quiz!
One factor showed a substantial...
08/07/2025
Rheumatology & Arthritis
Quiz
07/21/2025
Rebecca Mashaw
07/21/2025
Rheumatology & Arthritis
Quiz
08/30/2024
Riya Gandhi, MA
Is there any association between nonsteroidal anti-inflammatory drugs (NSAIDs), axial spondyloarthritis (axSpA), and risk of cardiovascular disease (CVD)?a) No, there is no evidence that NSAID use increases the risk of CVD on patients with...
Is there any association between nonsteroidal anti-inflammatory drugs (NSAIDs), axial spondyloarthritis (axSpA), and risk of cardiovascular disease (CVD)?a) No, there is no evidence that NSAID use increases the risk of CVD on patients with...
Is there any association between...
08/30/2024
Rheumatology & Arthritis
Quiz
08/07/2024
Rebecca Mashaw
What demographic characteristics are typical of patients with axial spondyloarthritis? Learn more when you take our quick quiz!
What demographic characteristics are typical of patients with axial spondyloarthritis? Learn more when you take our quick quiz!
What demographic characteristics...
08/07/2024
Rheumatology & Arthritis
Quiz
03/14/2024

Priyam Vora, Associate Editor

Priyam Vora, Associate Editor
Is obesity a risk and severity factor among patients with rheumatic conditions? Or does weight have no bearing on autoimmune disorders? Find out with one quick question!
Is obesity a risk and severity factor among patients with rheumatic conditions? Or does weight have no bearing on autoimmune disorders? Find out with one quick question!
Is obesity a risk and severity...
03/14/2024
Rheumatology & Arthritis
Quiz
02/22/2024
Priyam Vora
Researchers developed the Psoriatic Arthritis Risk Estimation Tool (PRESTO) to predict the 1- and 5-year risk of developing psoriatic arthritis in patients with psoriasis. Take our quiz to test your knowledge on the subject!
Researchers developed the Psoriatic Arthritis Risk Estimation Tool (PRESTO) to predict the 1- and 5-year risk of developing psoriatic arthritis in patients with psoriasis. Take our quiz to test your knowledge on the subject!
Researchers developed the...
02/22/2024
Rheumatology & Arthritis
Quiz
02/06/2024
Priyam Vora
Take a quick quiz to test your knowledge on gout, a form of arthritis typically characterized by severe pain, redness, and tenderness in joints.
Take a quick quiz to test your knowledge on gout, a form of arthritis typically characterized by severe pain, redness, and tenderness in joints.
Take a quick quiz to test your...
02/06/2024
Rheumatology & Arthritis
spinal xray
Quiz
02/01/2024
A retrospective cohort study identified 1426 adults with prevalent ankylosing spondylitis. Do you know the characteristic with the highest odds ratio to fractures among these patients? Take our quiz to test your knowledge!
A retrospective cohort study identified 1426 adults with prevalent ankylosing spondylitis. Do you know the characteristic with the highest odds ratio to fractures among these patients? Take our quiz to test your knowledge!
A retrospective cohort study...
02/01/2024
Rheumatology & Arthritis