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Upper Tract Urothelial Cancer Topic Center

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News
Analysis Maps Evolution of UTUC Cells
10/23/2024
Jolynn Tumolo
The molecular characteristics of primary and metastatic tumors in patients with upper tract urothelial carcinoma (UTUC) are mostly stable, suggesting that oncologists may be able to use analyses of primary tumor samples for molecular...
The molecular characteristics of primary and metastatic tumors in patients with upper tract urothelial carcinoma (UTUC) are mostly stable, suggesting that oncologists may be able to use analyses of primary tumor samples for molecular...
The molecular characteristics of...
10/23/2024
First Report Managed Care
News
Guideline Addresses Nonmetastatic Upper Tract Urothelial Carcinoma Management
10/10/2024
Lisa Kuhns, PhD, MD
An American Urological Association/Society of Urologic Oncology guideline published in the Journal of Urology provides more than 3 dozen recommendations to guide clinicians through a current evidence-based approach to the diagnosis and...
An American Urological Association/Society of Urologic Oncology guideline published in the Journal of Urology provides more than 3 dozen recommendations to guide clinicians through a current evidence-based approach to the diagnosis and...
An American Urological...
10/10/2024
First Report Managed Care
News
Treatment Combination Advances Metastatic Urothelial Cancer Care
09/23/2024
Jolynn Tumolo
Recent data has established enfortumab vedotin (EV) and pembrolizumab (P) as the preferred first-line (1L) treatment option for patients with metastatic urothelial cancer, according to an article in American Society of Clinical Oncology...
Recent data has established enfortumab vedotin (EV) and pembrolizumab (P) as the preferred first-line (1L) treatment option for patients with metastatic urothelial cancer, according to an article in American Society of Clinical Oncology...
Recent data has established...
09/23/2024
First Report Managed Care
News
Stereotactic Magnetic Resonance (MR)-Guided Radiotherapy Shows Promise for Inoperable Upper Tract Urothelial Carcinoma
09/03/2024
Lisa Kuhns, PhD, MD
Stereotactic MR-guided radiotherapy shows promise as an effective treatment for upper tract urothelial carcinoma (UTUC), particularly in patients who are not candidates for surgery, according to a case study presented in Frontiers in Oncology.
Stereotactic MR-guided radiotherapy shows promise as an effective treatment for upper tract urothelial carcinoma (UTUC), particularly in patients who are not candidates for surgery, according to a case study presented in Frontiers in Oncology.
Stereotactic MR-guided...
09/03/2024
First Report Managed Care
News
Study Finds Gemcitabine-Docetaxel Combo Outperforms BCG in Treating High-Risk Bladder Cancer
08/23/2024
Lisa Kuhns, PhD, MD
Gemcitabine and docetaxel therapy may be a viable alternative to bacillus Calmette-Guérin (BCG) for patients with high-risk non-muscle invasive bladder cancer (NMIBC), according to study results published in JAMA Network Open.
Gemcitabine and docetaxel therapy may be a viable alternative to bacillus Calmette-Guérin (BCG) for patients with high-risk non-muscle invasive bladder cancer (NMIBC), according to study results published in JAMA Network Open.
Gemcitabine and docetaxel...
08/23/2024
First Report Managed Care
News
Consensus and Divergence in International Guidelines for Upper Tract Urothelial Carcinoma Management
08/09/2024
Lisa Kuhns, PhD, MD
“In this study, we sought to systematically compare current international guidelines and recommendations and to identify both discrepancies and similarities regarding the management of UTUC,” wrote researchers.
“In this study, we sought to systematically compare current international guidelines and recommendations and to identify both discrepancies and similarities regarding the management of UTUC,” wrote researchers.
“In this study, we sought to...
08/09/2024
First Report Managed Care

Behind the Bill

Behind the Bill
The Senate’s $3 Trillion Deal. Tax Relief Now, Medicaid Coverage Loss Later?
07/02/2025
Katie Hayes, MJ
The Senate has done it. After weeks of behind-the-scenes wrangling and last-minute amendments, lawmakers have passed a sprawling tax-and-spending megabill that makes good on a long-standing Republican goal: making the 2017 Trump tax cuts...
The Senate has done it. After weeks of behind-the-scenes wrangling and last-minute amendments, lawmakers have passed a sprawling tax-and-spending megabill that makes good on a long-standing Republican goal: making the 2017 Trump tax cuts...
The Senate has done it. After...
07/02/2025
First Report Managed Care
Behind the Bill
When a Cap Isn’t Just a Cap: How a Provider Tax Proposal Could Reshape Medicaid Financing
06/25/2025
Katie Hayes, MJ
In Washington, the most consequential policies are often buried in the fine print. One such detail in the Senate Finance Committee’s latest tax and spending proposal would gradually cap provider taxes—a core funding tool states use to pull in...
In Washington, the most consequential policies are often buried in the fine print. One such detail in the Senate Finance Committee’s latest tax and spending proposal would gradually cap provider taxes—a core funding tool states use to pull in...
In Washington, the most...
06/25/2025
First Report Managed Care
Behind the Bill
Rewriting the Safety Net? Inside the Senate’s Changes to Medicaid and the ACA
06/18/2025
Katie Hayes, MJ
Over the past few weeks, I’ve been following the progress of the One Big Beautiful Bill Act (OBBBA), which started in the House with sweeping tax reforms and some eye-catching health care proposals. Now, the Senate has released its (highly...
Over the past few weeks, I’ve been following the progress of the One Big Beautiful Bill Act (OBBBA), which started in the House with sweeping tax reforms and some eye-catching health care proposals. Now, the Senate has released its (highly...
Over the past few weeks, I’ve...
06/18/2025
First Report Managed Care
Behind the Bill
How States Might Respond to the One Big Beautiful Bill Act
06/11/2025
Katie Hayes, MJ
With the One Big Beautiful Bill Act (OBBBA) still in the hands of the Senate, much of the national conversation has centered on what this legislation would do to federal coverage programs. But regardless of how the federal process unfolds,...
With the One Big Beautiful Bill Act (OBBBA) still in the hands of the Senate, much of the national conversation has centered on what this legislation would do to federal coverage programs. But regardless of how the federal process unfolds,...
With the One Big Beautiful Bill...
06/11/2025
First Report Managed Care
Behind the Bill
Is the Affordable Care Act on the Chopping Block? What the One Big Beautiful Bill Act Tells Us.
06/04/2025
Katie Hayes, MJ
It’s been weeks of headline-grabbing debate over Medicaid work requirements, and the “One Big Beautiful Bill Act” remains in the Senate as they deliberate over several health care provisions. While the Medicaid provisions sparked most of the...
It’s been weeks of headline-grabbing debate over Medicaid work requirements, and the “One Big Beautiful Bill Act” remains in the Senate as they deliberate over several health care provisions. While the Medicaid provisions sparked most of the...
It’s been weeks of...
06/04/2025
First Report Managed Care
Behind the Bill
From House to Senate: The Journey of Cutting Medicaid
05/28/2025
Katie Hayes, MJ
Last week, the House of Representatives narrowly passed the One Big Beautiful Bill Act (HR 1, 119th Congress) by a single vote, sending the sweeping tax and spending reconciliation package, backed by President Trump, to the Senate. With its...
Last week, the House of Representatives narrowly passed the One Big Beautiful Bill Act (HR 1, 119th Congress) by a single vote, sending the sweeping tax and spending reconciliation package, backed by President Trump, to the Senate. With its...
Last week, the House of...
05/28/2025
First Report Managed Care
Behind the Bill
Eligibility, Paperwork, and Penalties: The Not-So-Hidden Costs of Medicaid ‘Reform’
05/21/2025
Katie Hayes, MJ
It’s been another eventful week in health policy—a phrase that’s quickly becoming routine. This time, House Republicans advanced a sweeping budget reconciliation bill, designed to implement elements of the March budget resolution, with a...
It’s been another eventful week in health policy—a phrase that’s quickly becoming routine. This time, House Republicans advanced a sweeping budget reconciliation bill, designed to implement elements of the March budget resolution, with a...
It’s been another eventful week...
05/21/2025
First Report Managed Care
Behind the Bill
A Busy Week in Drug Pricing Policy: Aligning US Drug Prices With Global Standards?
05/14/2025
Katie Hayes, MJ
It’s been a busy few days for drug pricing policy. While I’d love to dig into the details of both President Trump’s latest executive order and the newest Republican bill that would cut Medicaid spending, we don’t have the time—and this isn’t...
It’s been a busy few days for drug pricing policy. While I’d love to dig into the details of both President Trump’s latest executive order and the newest Republican bill that would cut Medicaid spending, we don’t have the time—and this isn’t...
It’s been a busy few days for...
05/14/2025
First Report Managed Care
BEHIND THE BILL
When Agencies Lose Power: How 3 Seismic Shifts are Transforming Pharmaceutical Regulation
05/07/2025
Katie Hayes, MJ
In the span of just 9 months, the landscape of administrative law has undergone a transformation so profound that pharmaceutical executives, health care providers, and patients alike are struggling to navigate the new terrain. The Supreme...
In the span of just 9 months, the landscape of administrative law has undergone a transformation so profound that pharmaceutical executives, health care providers, and patients alike are struggling to navigate the new terrain. The Supreme...
In the span of just 9 months,...
05/07/2025
First Report Managed Care
Behind the Bill
The Medicare Paradox, Part 3: Strategic Trade Doesn’t Have to be a Zero-Sum Game
05/07/2025
Katie Hayes, MJ
Over the past 2 weeks, I’ve examined the growing friction between the Section 232 pharmaceutical tariff investigations and the Medicare drug pricing reforms authorized by the Inflation Reduction Act (IRA). These 2 policy agendas—industrial...
Over the past 2 weeks, I’ve examined the growing friction between the Section 232 pharmaceutical tariff investigations and the Medicare drug pricing reforms authorized by the Inflation Reduction Act (IRA). These 2 policy agendas—industrial...
Over the past 2 weeks, I’ve...
05/07/2025
First Report Managed Care

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Trending Articles

News
Few Medicare Providers Offer Intensive Behavioral Therapy for Obesity
10/13/2023
Jolynn Tumolo
A study found that only 1.2% of primary care providers offered Intensive Behavioral Therapy (IBT) services over 7 years, with some being consistent users, early adopters, and late adopters.
A study found that only 1.2% of primary care providers offered Intensive Behavioral Therapy (IBT) services over 7 years, with some being consistent users, early adopters, and late adopters.
A study found that only 1.2% of...
10/13/2023
First Report Managed Care
Samantha Roushan
Interview
Innovating Prior Authorization With Responsible AI
10/27/2023
Sam Roushan
Sam Roushan, Senior Vice President of Clinical Transformation at Cohere Health, shares how responsible AI is informed with sound clinical knowledge and can stay within ethical and legal boundaries and benefit payers, providers, and patients.
Sam Roushan, Senior Vice President of Clinical Transformation at Cohere Health, shares how responsible AI is informed with sound clinical knowledge and can stay within ethical and legal boundaries and benefit payers, providers, and patients.
Sam Roushan, Senior Vice...
10/27/2023
First Report Managed Care
News
Asthma Management Critical During Pregnancy
11/21/2023
Jolynn Tumolo
Potential roadblocks to adequate management of asthma in pregnant women include nonadherence to medication, lack of education, and smoking habits. The review mentions a retrospective study that found pregnant women with asthma tended to...
Potential roadblocks to adequate management of asthma in pregnant women include nonadherence to medication, lack of education, and smoking habits. The review mentions a retrospective study that found pregnant women with asthma tended to...
Potential roadblocks to adequate...
11/21/2023
First Report Managed Care
Sean Brady Headshot
Commentary
The Hidden Threat: Heart Failure in Elderly Diabetic Populations
01/04/2024
Sean Brady
The correlation between diabetes and heart failure poses a significant risk, as almost one-third of elderly individuals with diabetes encounter heart failure. Sean Brady provides insights into upcoming innovative solutions aimed at addressing...
The correlation between diabetes and heart failure poses a significant risk, as almost one-third of elderly individuals with diabetes encounter heart failure. Sean Brady provides insights into upcoming innovative solutions aimed at addressing...
The correlation between diabetes...
01/04/2024
First Report Managed Care
Feature Story
Medical Cost Increases Projected for 2024
03/01/2024
Paul Nicolaus
PwC's Health Research Institute surveyed health plan actuaries covering nearly 100 million employer-sponsored and 10 million Affordable Care Act marketplace members to project medical cost trends for 2023-2024, highlighting factors like...
PwC's Health Research Institute surveyed health plan actuaries covering nearly 100 million employer-sponsored and 10 million Affordable Care Act marketplace members to project medical cost trends for 2023-2024, highlighting factors like...
PwC's Health Research Institute...
03/01/2024
First Report Managed Care

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