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Multiple Myeloma Topic Center

Featured Article

News
12/02/2025
Grace Taylor, MS, MA
A study presented at the 22nd International Myeloma Society (IMS) Annual Meeting shows that extramedullary disease significantly increases health care utilization and costs for patients with triple-class–exposed (TCE) relapsed/refractory...
A study presented at the 22nd International Myeloma Society (IMS) Annual Meeting shows that extramedullary disease significantly increases health care utilization and costs for patients with triple-class–exposed (TCE) relapsed/refractory...
A study presented at the 22nd...
12/02/2025
First Report Managed Care
News
11/17/2025
Grace Taylor, MS, MA
A US claims study reveals that patients with relapsed or refractory multiple myeloma (RRMM) who discontinue lenalidomide face overwhelming monthly health care costs driven primarily by drug and infusion expenses.
A US claims study reveals that patients with relapsed or refractory multiple myeloma (RRMM) who discontinue lenalidomide face overwhelming monthly health care costs driven primarily by drug and infusion expenses.
A US claims study reveals that...
11/17/2025
First Report Managed Care
News
11/10/2025
Hannah Musick
In a pooled analysis of GRIFFIN and PERSEUS, transplant-eligible adults aged ≥65 years with newly diagnosed multiple myeloma who received daratumumab-VRd followed by D-R achieved deeper responses and higher MRD-negativity with a trend toward...
In a pooled analysis of GRIFFIN and PERSEUS, transplant-eligible adults aged ≥65 years with newly diagnosed multiple myeloma who received daratumumab-VRd followed by D-R achieved deeper responses and higher MRD-negativity with a trend toward...
In a pooled analysis of GRIFFIN...
11/10/2025
First Report Managed Care
Jagannath
CONFERENCE COVERAGE
10/17/2025
Sundar Jagannath, MBBS
At SOHO 2025, Sundar Jagannath, MBBS, joined Noopur Raje, MD, Krina Patel, MD, and other experts to discuss groundbreaking advances in CAR T-cell, bispecific, and trispecific therapies that are transforming multiple myeloma from a chronic...
At SOHO 2025, Sundar Jagannath, MBBS, joined Noopur Raje, MD, Krina Patel, MD, and other experts to discuss groundbreaking advances in CAR T-cell, bispecific, and trispecific therapies that are transforming multiple myeloma from a chronic...
At SOHO 2025, Sundar Jagannath,...
10/17/2025
First Report Managed Care
News
10/10/2025
Hannah Musick
Both patients and providers ranked progression-free survival as the most important treatment attribute in multiple myeloma, but also strongly valued the ability to live without ongoing treatment and the presence of scientific innovation.
Both patients and providers ranked progression-free survival as the most important treatment attribute in multiple myeloma, but also strongly valued the ability to live without ongoing treatment and the presence of scientific innovation.
Both patients and providers...
10/10/2025
First Report Managed Care
Lonial
CONFERENCE COVERAGE
10/10/2025
Sagar Lonial, MD
Dr Sagar Lonial discusses his SOHO 2025 case presentation on evolving definitions of high-risk smoldering multiple myeloma, the growing evidence for early intervention, and how innovations such as CAR T-cell therapies and bispecific...
Dr Sagar Lonial discusses his SOHO 2025 case presentation on evolving definitions of high-risk smoldering multiple myeloma, the growing evidence for early intervention, and how innovations such as CAR T-cell therapies and bispecific...
Dr Sagar Lonial discusses his...
10/10/2025
First Report Managed Care
News
10/07/2025
Grace Taylor, MS, MA
A large Veterans Health Administration (VHA) study found no significant difference in multiple myeloma incidence between patients with rheumatoid arthritis treated with biologic or targeted synthetic disease-modifying anti-rheumatic drugs...
A large Veterans Health Administration (VHA) study found no significant difference in multiple myeloma incidence between patients with rheumatoid arthritis treated with biologic or targeted synthetic disease-modifying anti-rheumatic drugs...
A large Veterans Health...
10/07/2025
First Report Managed Care
Usmani Headshot
Conference Coverage
09/08/2025
Saad Z. Usmani, MD, FACP
Dr Saad Usmani, chief of the myeloma service at Memorial Sloan Kettering Cancer Center, explores the evolving debate on early intervention for high-risk smoldering multiple myeloma, highlighting pivotal trial data and its potential to reshape...
Dr Saad Usmani, chief of the myeloma service at Memorial Sloan Kettering Cancer Center, explores the evolving debate on early intervention for high-risk smoldering multiple myeloma, highlighting pivotal trial data and its potential to reshape...
Dr Saad Usmani, chief of the...
09/08/2025
First Report Managed Care
Martin
Conference Coverage
09/03/2025
Thomas G. Martin, III, MD
Dr Thomas Martin previews his SOHO 2025 session and explores the pressing next questions in multiple myeloma, including when to treat smoldering disease, how to better define and manage high-risk patients, and how innovations like bispecifics...
Dr Thomas Martin previews his SOHO 2025 session and explores the pressing next questions in multiple myeloma, including when to treat smoldering disease, how to better define and manage high-risk patients, and how innovations like bispecifics...
Dr Thomas Martin previews his...
09/03/2025
First Report Managed Care
Raje Headshot
Conference Coverage
09/02/2025
Noopur S. Raje, MD
At SOHO 2025, Dr Noopur Raje will present a cutting-edge overview of CAR T-cell therapy in multiple myeloma, highlighting long-term efficacy data, novel targets like GPRC5D, emerging dual-targeting and in vivo CAR strategies, and the evolving...
At SOHO 2025, Dr Noopur Raje will present a cutting-edge overview of CAR T-cell therapy in multiple myeloma, highlighting long-term efficacy data, novel targets like GPRC5D, emerging dual-targeting and in vivo CAR strategies, and the evolving...
At SOHO 2025, Dr Noopur Raje...
09/02/2025
First Report Managed Care
News
07/23/2025
Grace Taylor, MS, MA
The ADVANCE trial shows that adding daratumumab to carfilzomib-lenalidomide-dexamethasone (KRd) significantly improves minimal residual disease (MRD) negativity in newly diagnosed multiple myeloma, according to a study presented at the 2025...
The ADVANCE trial shows that adding daratumumab to carfilzomib-lenalidomide-dexamethasone (KRd) significantly improves minimal residual disease (MRD) negativity in newly diagnosed multiple myeloma, according to a study presented at the 2025...
The ADVANCE trial shows that...
07/23/2025
First Report Managed Care

Newsfeed

News
12/02/2025
Grace Taylor, MS, MA
A study presented at the 22nd International Myeloma Society (IMS) Annual Meeting shows that extramedullary disease significantly increases health care utilization and costs for patients with triple-class–exposed (TCE) relapsed/refractory...
A study presented at the 22nd International Myeloma Society (IMS) Annual Meeting shows that extramedullary disease significantly increases health care utilization and costs for patients with triple-class–exposed (TCE) relapsed/refractory...
A study presented at the 22nd...
12/02/2025
First Report Managed Care
News
11/17/2025
Grace Taylor, MS, MA
A US claims study reveals that patients with relapsed or refractory multiple myeloma (RRMM) who discontinue lenalidomide face overwhelming monthly health care costs driven primarily by drug and infusion expenses.
A US claims study reveals that patients with relapsed or refractory multiple myeloma (RRMM) who discontinue lenalidomide face overwhelming monthly health care costs driven primarily by drug and infusion expenses.
A US claims study reveals that...
11/17/2025
First Report Managed Care
News
11/10/2025
Hannah Musick
In a pooled analysis of GRIFFIN and PERSEUS, transplant-eligible adults aged ≥65 years with newly diagnosed multiple myeloma who received daratumumab-VRd followed by D-R achieved deeper responses and higher MRD-negativity with a trend toward...
In a pooled analysis of GRIFFIN and PERSEUS, transplant-eligible adults aged ≥65 years with newly diagnosed multiple myeloma who received daratumumab-VRd followed by D-R achieved deeper responses and higher MRD-negativity with a trend toward...
In a pooled analysis of GRIFFIN...
11/10/2025
First Report Managed Care
News
10/10/2025
Hannah Musick
Both patients and providers ranked progression-free survival as the most important treatment attribute in multiple myeloma, but also strongly valued the ability to live without ongoing treatment and the presence of scientific innovation.
Both patients and providers ranked progression-free survival as the most important treatment attribute in multiple myeloma, but also strongly valued the ability to live without ongoing treatment and the presence of scientific innovation.
Both patients and providers...
10/10/2025
First Report Managed Care
News
10/07/2025
Grace Taylor, MS, MA
A large Veterans Health Administration (VHA) study found no significant difference in multiple myeloma incidence between patients with rheumatoid arthritis treated with biologic or targeted synthetic disease-modifying anti-rheumatic drugs...
A large Veterans Health Administration (VHA) study found no significant difference in multiple myeloma incidence between patients with rheumatoid arthritis treated with biologic or targeted synthetic disease-modifying anti-rheumatic drugs...
A large Veterans Health...
10/07/2025
First Report Managed Care
News
07/23/2025
Grace Taylor, MS, MA
The ADVANCE trial shows that adding daratumumab to carfilzomib-lenalidomide-dexamethasone (KRd) significantly improves minimal residual disease (MRD) negativity in newly diagnosed multiple myeloma, according to a study presented at the 2025...
The ADVANCE trial shows that adding daratumumab to carfilzomib-lenalidomide-dexamethasone (KRd) significantly improves minimal residual disease (MRD) negativity in newly diagnosed multiple myeloma, according to a study presented at the 2025...
The ADVANCE trial shows that...
07/23/2025
First Report Managed Care
News
10/18/2024
Jolynn Tumolo
Peripheral residual disease identified using next-generation flow in patients with transplant-eligible multiple myeloma was associated with a 13-fold increased risk of progression or death, according to a clinical trial update published...
Peripheral residual disease identified using next-generation flow in patients with transplant-eligible multiple myeloma was associated with a 13-fold increased risk of progression or death, according to a clinical trial update published...
Peripheral residual disease...
10/18/2024
First Report Managed Care
News
12/22/2022
Edan Stanley
Authors shared updated efficacy and safety data from the phase 3 CANDOR study in which patients with relapsed or refractory multiple myeloma were treated with two combination therapy options.
Authors shared updated efficacy and safety data from the phase 3 CANDOR study in which patients with relapsed or refractory multiple myeloma were treated with two combination therapy options.
Authors shared updated efficacy...
12/22/2022
First Report Managed Care
News
12/21/2022
Jolynn Tumolo
Researchers reviewed data from the MASTER and GRIFFIN trials to determine whether patients could undergo stem cell transplants after receiving induction therapy that included daratumumab and lenolidamide. 
Researchers reviewed data from the MASTER and GRIFFIN trials to determine whether patients could undergo stem cell transplants after receiving induction therapy that included daratumumab and lenolidamide. 
Researchers reviewed data from...
12/21/2022
First Report Managed Care
News
12/15/2022
Jolynn Tumolo
Researchers studied a heavily pretreated patient population to determine which drugs were being administered, as well as their impact on overall survival.
Researchers studied a heavily pretreated patient population to determine which drugs were being administered, as well as their impact on overall survival.
Researchers studied a heavily...
12/15/2022
First Report Managed Care
News
03/20/2026
Lisa Kuhns, PhD, MD
Machine learning models may help clinicians pinpoint which older patients with rheumatoid arthritis are most likely to fall off therapy—before it happens.
Machine learning models may help clinicians pinpoint which older patients with rheumatoid arthritis are most likely to fall off therapy—before it happens.
Machine learning models may help...
03/20/2026
First Report Managed Care
Behind the Bill
03/19/2026
Hannah Musick
A sweeping proposed Affordable Care Act (ACA) Marketplace rule for 2027 is drawing sharp pushback from states, setting up a high-stakes debate over coverage, affordability, and program integrity.
A sweeping proposed Affordable Care Act (ACA) Marketplace rule for 2027 is drawing sharp pushback from states, setting up a high-stakes debate over coverage, affordability, and program integrity.
A sweeping proposed Affordable...
03/19/2026
First Report Managed Care
News
03/18/2026
Hannah Musick
A systematic review of diffuse large B-cell lymphoma (DLBCL) registration trials found that while most primary outcomes are reported for older adults, key data on secondary endpoints, toxicity, and quality of life remain largely missing,...
A systematic review of diffuse large B-cell lymphoma (DLBCL) registration trials found that while most primary outcomes are reported for older adults, key data on secondary endpoints, toxicity, and quality of life remain largely missing,...
A systematic review of diffuse...
03/18/2026
First Report Managed Care
News
03/18/2026
Lisa Kuhns, PhD, MD
Decades of clinical trials are reshaping diabetic kidney disease care, with combination therapies now delivering unprecedented gains in renal and cardiovascular outcomes.
Decades of clinical trials are reshaping diabetic kidney disease care, with combination therapies now delivering unprecedented gains in renal and cardiovascular outcomes.
Decades of clinical trials are...
03/18/2026
First Report Managed Care
News
03/17/2026
Grace Taylor, MS, MA
Fixed-duration epcoritamab combined with rituximab plus lenalidomide (R2) delivers high complete response rates and durable remissions in relapsed or refractory (R/R) follicular lymphoma, according to a study published in Blood.
Fixed-duration epcoritamab combined with rituximab plus lenalidomide (R2) delivers high complete response rates and durable remissions in relapsed or refractory (R/R) follicular lymphoma, according to a study published in Blood.
Fixed-duration epcoritamab...
03/17/2026
First Report Managed Care
News
03/16/2026
Lisa Kuhns, PhD, MD
Bispecific antibodies are emerging as an effective, off-the-shelf option for relapsed or refractory diffuse large B-cell lymphoma (DLBCL), with promising response rates and growing evidence that they can be delivered safely in community...
Bispecific antibodies are emerging as an effective, off-the-shelf option for relapsed or refractory diffuse large B-cell lymphoma (DLBCL), with promising response rates and growing evidence that they can be delivered safely in community...
Bispecific antibodies are...
03/16/2026
First Report Managed Care
News
03/13/2026
Lisa Kuhns, PhD, MD
A real-world study suggests semaglutide not only drives meaningful weight loss but may also improve muscle strength and reduce sarcopenic obesity in patients with severe obesity.
A real-world study suggests semaglutide not only drives meaningful weight loss but may also improve muscle strength and reduce sarcopenic obesity in patients with severe obesity.
A real-world study suggests...
03/13/2026
First Report Managed Care
Behind the Bill
03/13/2026
Grace Taylor, MS, MA
A bipartisan Senate bill advancing toward floor consideration would mandate new cybersecurity standards under the Health Insurance Portability and Accountability Act, strengthen federal oversight, and expand breach transparency.
A bipartisan Senate bill advancing toward floor consideration would mandate new cybersecurity standards under the Health Insurance Portability and Accountability Act, strengthen federal oversight, and expand breach transparency.
A bipartisan Senate bill...
03/13/2026
First Report Managed Care
News
03/12/2026
Lisa Kuhns, PhD, MD
A single bispecific antibody used across multiple lymphoma indications could save oncology practices hundreds of thousands of dollars and thousands of staff hours annually, according to a new mixed-methods analysis published in Future...
A single bispecific antibody used across multiple lymphoma indications could save oncology practices hundreds of thousands of dollars and thousands of staff hours annually, according to a new mixed-methods analysis published in Future...
A single bispecific antibody...
03/12/2026
First Report Managed Care
News
03/11/2026
Hannah Musick
In an indirect comparison of third-line or later follicular lymphoma, epcoritamab demonstrated significantly higher response rates vs chemoimmunotherapy and favorable safety compared with other bispecific antibodies.
In an indirect comparison of third-line or later follicular lymphoma, epcoritamab demonstrated significantly higher response rates vs chemoimmunotherapy and favorable safety compared with other bispecific antibodies.
In an indirect comparison of...
03/11/2026
First Report Managed Care

Insights

Jagannath
CONFERENCE COVERAGE
10/17/2025
Sundar Jagannath, MBBS
At SOHO 2025, Sundar Jagannath, MBBS, joined Noopur Raje, MD, Krina Patel, MD, and other experts to discuss groundbreaking advances in CAR T-cell, bispecific, and trispecific therapies that are transforming multiple myeloma from a chronic...
At SOHO 2025, Sundar Jagannath, MBBS, joined Noopur Raje, MD, Krina Patel, MD, and other experts to discuss groundbreaking advances in CAR T-cell, bispecific, and trispecific therapies that are transforming multiple myeloma from a chronic...
At SOHO 2025, Sundar Jagannath,...
10/17/2025
First Report Managed Care
Lonial
CONFERENCE COVERAGE
10/10/2025
Sagar Lonial, MD
Dr Sagar Lonial discusses his SOHO 2025 case presentation on evolving definitions of high-risk smoldering multiple myeloma, the growing evidence for early intervention, and how innovations such as CAR T-cell therapies and bispecific...
Dr Sagar Lonial discusses his SOHO 2025 case presentation on evolving definitions of high-risk smoldering multiple myeloma, the growing evidence for early intervention, and how innovations such as CAR T-cell therapies and bispecific...
Dr Sagar Lonial discusses his...
10/10/2025
First Report Managed Care
Headshot of Dr Hira Shaikh, University of Iowa
Interview
01/19/2023
Maria Asimopoulos
Hira Shaikh, MD, assistant professor of hematology, oncology, and bone marrow transplant, University of Iowa Hospitals and Clinics, walks through the details of her study which compared multiple myeloma survival outcomes among Hispanic vs...
Hira Shaikh, MD, assistant professor of hematology, oncology, and bone marrow transplant, University of Iowa Hospitals and Clinics, walks through the details of her study which compared multiple myeloma survival outcomes among Hispanic vs...
Hira Shaikh, MD, assistant...
01/19/2023
First Report Managed Care
Headshot of Joshua Richter, MD, Mount Sinai
Interview
10/18/2022
Maria Asimopoulos
Joshua Richter, MD, associate professor of medicine, hematology, and oncology, Tisch Cancer Institute, Icahn School of Medicine, Mount Sinai, reviews real-world data presented at the SOHO 2022 Annual Meeting in which combination bortezomib,...
Joshua Richter, MD, associate professor of medicine, hematology, and oncology, Tisch Cancer Institute, Icahn School of Medicine, Mount Sinai, reviews real-world data presented at the SOHO 2022 Annual Meeting in which combination bortezomib,...
Joshua Richter, MD, associate...
10/18/2022
First Report Managed Care