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Chronic Myeloid Leukemia

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News
06/08/2026
Grace Taylor, MS, MA
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with...
06/08/2026
First Report Managed Care
News
05/20/2026
Hannah Musick
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib...
05/20/2026
First Report Managed Care
News
12/28/2021
Jolynn Tumolo
Generic versions of imatinib were comparable in bioequivalence and bioavailability to the branded drug across studies, according to recent findings.
Generic versions of imatinib were comparable in bioequivalence and bioavailability to the branded drug across studies, according to recent findings.
Generic versions of imatinib...
12/28/2021
First Report Managed Care
News
12/07/2021
Jolynn Tumolo
Among patients with chronic myeloid leukemia who had already been treated with at least two tyrosine kinase inhibitors, asciminib resulted in greater major molecular response than bosutinib.
Among patients with chronic myeloid leukemia who had already been treated with at least two tyrosine kinase inhibitors, asciminib resulted in greater major molecular response than bosutinib.
Among patients with chronic...
12/07/2021
First Report Managed Care
News
12/01/2021
Jolynn Tumolo
Researchers concluded that asciminib was safe and effective in patients with chronic myeloid leukemia who did not benefit from alternative treatments in clinical practice.
Researchers concluded that asciminib was safe and effective in patients with chronic myeloid leukemia who did not benefit from alternative treatments in clinical practice.
Researchers concluded that...
12/01/2021
First Report Managed Care
News
11/01/2021
The FDA granted accelerated approval to asciminib for the use in the treatment of patients with Ph+ CML in CP with or without the T315I mutation who were previously treated with 2 or more TKIs.
The FDA granted accelerated approval to asciminib for the use in the treatment of patients with Ph+ CML in CP with or without the T315I mutation who were previously treated with 2 or more TKIs.
The FDA granted accelerated...
11/01/2021
Oncology
From Oncology
News
09/20/2021
The increase in use of TKIs for patients with CML and the increase in TKI drug prices place considerable financial pressure on Medicare part-D insurers.
The increase in use of TKIs for patients with CML and the increase in TKI drug prices place considerable financial pressure on Medicare part-D insurers.
The increase in use of TKIs for...
09/20/2021
Journal of Clinical Pathways
From Journal of Clinical Pathways
News
03/12/2021
Maria Asimopoulos
“With the increasing discovery of the involvement of further molecules and pathways, we believe the scientific community will—at some point—be able to achieve TFR in our patient population and, finally, target and eradicate CML once and for...
“With the increasing discovery of the involvement of further molecules and pathways, we believe the scientific community will—at some point—be able to achieve TFR in our patient population and, finally, target and eradicate CML once and for...
“With the increasing discovery...
03/12/2021
First Report Managed Care
News
03/09/2021
Maria Asimopoulos
“Overall efficacy and safety results support the use of nilotinib 300 mg [twice daily] as frontline therapy for optimal long-term outcomes, especially in patients aiming for [treatment-free remission],” researchers concluded.
“Overall efficacy and safety results support the use of nilotinib 300 mg [twice daily] as frontline therapy for optimal long-term outcomes, especially in patients aiming for [treatment-free remission],” researchers concluded.
“Overall efficacy and safety...
03/09/2021
First Report Managed Care
News
02/18/2021
Maria Asimopoulos
“Our results provide important new information to inform the discussion between patients with CML and clinicians about the risks and benefits of TKI discontinuation and the potential to assess TKI cessation more accurately,” researchers...
“Our results provide important new information to inform the discussion between patients with CML and clinicians about the risks and benefits of TKI discontinuation and the potential to assess TKI cessation more accurately,” researchers...
“Our results provide important...
02/18/2021
First Report Managed Care
News
02/14/2014
The FDA granted full approval on Thursday for Synribo (omacetaxine mepesuccinate), according to a news release from Teva Pharmaceuticals, the drug's manufacturer. The injectable drug was initially approved under the FDA's accelerated approval...
The FDA granted full approval on Thursday for Synribo (omacetaxine mepesuccinate), according to a news release from Teva Pharmaceuticals, the drug's manufacturer. The injectable drug was initially approved under the FDA's accelerated approval...
The FDA granted full approval on...
02/14/2014
First Report Managed Care

Newsfeed

News
06/08/2026
Grace Taylor, MS, MA
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with...
06/08/2026
First Report Managed Care
News
05/20/2026
Hannah Musick
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib demonstrated higher major molecular response rates and fewer treatment discontinuations due to adverse events compared with imatinib and second-generation tyrosine kinase inhibitors in newly diagnosed chronic myeloid...
At 96 weeks, asciminib...
05/20/2026
First Report Managed Care
News
12/28/2021
Jolynn Tumolo
Generic versions of imatinib were comparable in bioequivalence and bioavailability to the branded drug across studies, according to recent findings.
Generic versions of imatinib were comparable in bioequivalence and bioavailability to the branded drug across studies, according to recent findings.
Generic versions of imatinib...
12/28/2021
First Report Managed Care
News
12/07/2021
Jolynn Tumolo
Among patients with chronic myeloid leukemia who had already been treated with at least two tyrosine kinase inhibitors, asciminib resulted in greater major molecular response than bosutinib.
Among patients with chronic myeloid leukemia who had already been treated with at least two tyrosine kinase inhibitors, asciminib resulted in greater major molecular response than bosutinib.
Among patients with chronic...
12/07/2021
First Report Managed Care
News
12/01/2021
Jolynn Tumolo
Researchers concluded that asciminib was safe and effective in patients with chronic myeloid leukemia who did not benefit from alternative treatments in clinical practice.
Researchers concluded that asciminib was safe and effective in patients with chronic myeloid leukemia who did not benefit from alternative treatments in clinical practice.
Researchers concluded that...
12/01/2021
First Report Managed Care
News
11/01/2021
The FDA granted accelerated approval to asciminib for the use in the treatment of patients with Ph+ CML in CP with or without the T315I mutation who were previously treated with 2 or more TKIs.
The FDA granted accelerated approval to asciminib for the use in the treatment of patients with Ph+ CML in CP with or without the T315I mutation who were previously treated with 2 or more TKIs.
The FDA granted accelerated...
11/01/2021
Oncology
News
09/20/2021
The increase in use of TKIs for patients with CML and the increase in TKI drug prices place considerable financial pressure on Medicare part-D insurers.
The increase in use of TKIs for patients with CML and the increase in TKI drug prices place considerable financial pressure on Medicare part-D insurers.
The increase in use of TKIs for...
09/20/2021
Journal of Clinical Pathways
News
03/12/2021
Maria Asimopoulos
“With the increasing discovery of the involvement of further molecules and pathways, we believe the scientific community will—at some point—be able to achieve TFR in our patient population and, finally, target and eradicate CML once and for...
“With the increasing discovery of the involvement of further molecules and pathways, we believe the scientific community will—at some point—be able to achieve TFR in our patient population and, finally, target and eradicate CML once and for...
“With the increasing discovery...
03/12/2021
First Report Managed Care
News
03/09/2021
Maria Asimopoulos
“Overall efficacy and safety results support the use of nilotinib 300 mg [twice daily] as frontline therapy for optimal long-term outcomes, especially in patients aiming for [treatment-free remission],” researchers concluded.
“Overall efficacy and safety results support the use of nilotinib 300 mg [twice daily] as frontline therapy for optimal long-term outcomes, especially in patients aiming for [treatment-free remission],” researchers concluded.
“Overall efficacy and safety...
03/09/2021
First Report Managed Care
News
02/18/2021
Maria Asimopoulos
“Our results provide important new information to inform the discussion between patients with CML and clinicians about the risks and benefits of TKI discontinuation and the potential to assess TKI cessation more accurately,” researchers...
“Our results provide important new information to inform the discussion between patients with CML and clinicians about the risks and benefits of TKI discontinuation and the potential to assess TKI cessation more accurately,” researchers...
“Our results provide important...
02/18/2021
First Report Managed Care
News
06/15/2026
Hannah Musick
Population health management strategies that combine early chronic kidney disease (CKD) detection, risk stratification, and integrated primary-nephrology care may help reduce disease progression, cardiovascular complications, and health care...
Population health management strategies that combine early chronic kidney disease (CKD) detection, risk stratification, and integrated primary-nephrology care may help reduce disease progression, cardiovascular complications, and health care...
Population health management...
06/15/2026
First Report Managed Care
Behind the Bill
06/12/2026
Grace Taylor, MS, MA
As the Centers for Medicare & Medicaid Services (CMS) intensifies its review of Medicaid demonstration waivers and state-directed payments, managed care stakeholders are assessing what heightened federal scrutiny could mean for program...
As the Centers for Medicare & Medicaid Services (CMS) intensifies its review of Medicaid demonstration waivers and state-directed payments, managed care stakeholders are assessing what heightened federal scrutiny could mean for program...
As the Centers for Medicare &...
06/12/2026
First Report Managed Care
News
06/11/2026
Hannah Musick
Datopotamab deruxtecan plus pembrolizumab, with or without platinum-based chemotherapy, produced durable responses and manageable safety across programmed death-ligand 1 expression levels in patients with advanced non–small cell lung cancer...
Datopotamab deruxtecan plus pembrolizumab, with or without platinum-based chemotherapy, produced durable responses and manageable safety across programmed death-ligand 1 expression levels in patients with advanced non–small cell lung cancer...
Datopotamab deruxtecan plus...
06/11/2026
First Report Managed Care
News
06/09/2026
Rebecca Amrick
Obstetrician/gynecologist (OB/GYN) offices may serve as an additional setting to inform women on colorectal cancer (CRC) and provide preventative screenings, but discrepancies in care still exist based on age, race, income, and insurance...
Obstetrician/gynecologist (OB/GYN) offices may serve as an additional setting to inform women on colorectal cancer (CRC) and provide preventative screenings, but discrepancies in care still exist based on age, race, income, and insurance...
Obstetrician/gynecologist...
06/09/2026
First Report Managed Care
News
06/08/2026
Grace Taylor, MS, MA
Pneumonia-related hospitalizations among patients with multiple myeloma are becoming increasingly costly despite declining mortality rates, highlighting persistent disparities and the urgent need for strategies to prevent serious infections...
Pneumonia-related hospitalizations among patients with multiple myeloma are becoming increasingly costly despite declining mortality rates, highlighting persistent disparities and the urgent need for strategies to prevent serious infections...
Pneumonia-related...
06/08/2026
First Report Managed Care
News
06/08/2026
Grace Taylor, MS, MA
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with chronic myeloid leukemia (CML) found that food restrictions associated with certain tyrosine kinase inhibitors (TKIs) may complicate daily routines, reduce treatment adherence, and increase interest in more...
A US survey of patients with...
06/08/2026
First Report Managed Care
News
06/05/2026
Grace Taylor, MS, MA
Clinical pharmacists nearly doubled SGLT2 inhibitor initiation among veterans with chronic kidney disease (CKD) and type 2 diabetes in a large US Department of Veterans Affairs quality improvement study.
Clinical pharmacists nearly doubled SGLT2 inhibitor initiation among veterans with chronic kidney disease (CKD) and type 2 diabetes in a large US Department of Veterans Affairs quality improvement study.
Clinical pharmacists nearly...
06/05/2026
First Report Managed Care
News
06/05/2026
Rebecca Amrick
Researchers examined epidural spinal injections as a candidate for de-implementation, specifically for patients with chronic low back pain, and provided suggestions for successfully redirecting care toward more effective and sustainable...
Researchers examined epidural spinal injections as a candidate for de-implementation, specifically for patients with chronic low back pain, and provided suggestions for successfully redirecting care toward more effective and sustainable...
Researchers examined epidural...
06/05/2026
First Report Managed Care
News
06/04/2026
Rebecca Amrick
A clinical trial comparing CT-P39 with reference omalizumab found both drugs to be comparable both in efficacy and safety, indicating CT-P39 as a suitable alternative to omalizumab for patients with chronic spontaneous urticaria (CSU).
A clinical trial comparing CT-P39 with reference omalizumab found both drugs to be comparable both in efficacy and safety, indicating CT-P39 as a suitable alternative to omalizumab for patients with chronic spontaneous urticaria (CSU).
A clinical trial comparing...
06/04/2026
First Report Managed Care
Behind the Bill
05/29/2026
Grace Taylor, MS, MA
The Centers for Medicare & Medicaid Services (CMS) has finalized updates to the federal Independent Dispute Resolution (IDR) process under the No Surprises Act, lowering administrative fees, creating a centralized dispute portal, and...
The Centers for Medicare & Medicaid Services (CMS) has finalized updates to the federal Independent Dispute Resolution (IDR) process under the No Surprises Act, lowering administrative fees, creating a centralized dispute portal, and...
The Centers for Medicare &...
05/29/2026
First Report Managed Care