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Study Finds Rising PrEP Use and Declining Costs Amid Shift to Generics
04/02/2025
Grace Taylor, MS, MA
A recent study shows rising pre-exposure prophylaxis (PrEP) utilization and declining costs as generic formulations replace branded versions in HIV prevention.
A recent study shows rising pre-exposure prophylaxis (PrEP) utilization and declining costs as generic formulations replace branded versions in HIV prevention.
A recent study shows rising...
04/02/2025
First Report Managed Care
News
HIV Cases Rise Among Gay Latinos
07/24/2024
Grace Taylor, MS, MA
As HIV rates continue to rise among Latino gay and bisexual men, health policy advocates stress the need for more federal assistance for HIV treatment and prevention in this community.
As HIV rates continue to rise among Latino gay and bisexual men, health policy advocates stress the need for more federal assistance for HIV treatment and prevention in this community.
As HIV rates continue to rise...
07/24/2024
First Report Managed Care
News
Injectable PrEP Overall Acceptable, Preferred for HIV Prevention
07/15/2023
Maria Asimopoulos
“Given overall acceptability, injectable PrEP should be included as part of a menu of prevention options, allowing end-users to select the modality that suits their preferences, needs and lifestyle,” researchers advised.
“Given overall acceptability, injectable PrEP should be included as part of a menu of prevention options, allowing end-users to select the modality that suits their preferences, needs and lifestyle,” researchers advised.
“Given overall acceptability,...
07/15/2023
First Report Managed Care
News
Study Estimates Billable Per Patient Costs of Providing PrEP
12/20/2022
Jolynn Tumolo
Researchers used clinic billing records in Washington, DC and Chicago to estimate the annual billable costs associated with the use of preexposure prophylaxis for HIV.
Researchers used clinic billing records in Washington, DC and Chicago to estimate the annual billable costs associated with the use of preexposure prophylaxis for HIV.
Researchers used clinic billing...
12/20/2022
First Report Managed Care
News
Women View PrEP Services as a Natural Extension of OB/GYN Care
11/17/2022
Jolynn Tumolo
“Multiple participants suggested that initial counseling on PrEP should be offered universally to patients, regardless of sexual history or personal risk factors,” researchers advised.
“Multiple participants suggested that initial counseling on PrEP should be offered universally to patients, regardless of sexual history or personal risk factors,” researchers advised.
“Multiple participants suggested...
11/17/2022
First Report Managed Care
News
Black Sexual Minority Men Report Higher Prevalence of PrEP Use Than White Men
11/14/2022
Jolynn Tumolo
Investigators conducted a survey to determine how prevalent the use of pre- and post-exposure prophylaxis was among over 63,000 participants.
Investigators conducted a survey to determine how prevalent the use of pre- and post-exposure prophylaxis was among over 63,000 participants.
Investigators conducted a survey...
11/14/2022
First Report Managed Care
News
PrEP Most Effective for Reducing HIV Incidence in Men Who Have Sex With Men
11/07/2022
Jolynn Tumolo
Among a variety of interventions, pre-exposure prophylaxis was the only method that showed consistent effectiveness in reducing the incidence of HIV, new findings show.
Among a variety of interventions, pre-exposure prophylaxis was the only method that showed consistent effectiveness in reducing the incidence of HIV, new findings show.
Among a variety of...
11/07/2022
First Report Managed Care
News
Positive Sources of PrEP Awareness Include Partners, Peers, Health Promotions
09/27/2022
Jolynn Tumolo
"Messages from health campaigns were perceived as most positive, and those from religious institutions as least positive," authors said.
"Messages from health campaigns were perceived as most positive, and those from religious institutions as least positive," authors said.
"Messages from health campaigns...
09/27/2022
First Report Managed Care
News
Monitoring HIV Strains to Prevent PrEP Failure, Viral Transmission
09/09/2022
Jolynn Tumolo
Study authors employed a strategy to monitor populations for HIV strains that are resistant to tenofovir and emtricitabine and ensure PrEP failure rates remain rare.
Study authors employed a strategy to monitor populations for HIV strains that are resistant to tenofovir and emtricitabine and ensure PrEP failure rates remain rare.
Study authors employed a...
09/09/2022
First Report Managed Care
News
High Distress in Black MSM Lowers Odds of Antiretroviral Therapy Adherence
09/02/2022
Jolynn Tumolo
High rates of psychological distress may represent an important barrier against HIV treatment adherence for Black men who have sex with men living in urban areas, researchers said.
High rates of psychological distress may represent an important barrier against HIV treatment adherence for Black men who have sex with men living in urban areas, researchers said.
High rates of psychological...
09/02/2022
First Report Managed Care
News
Social Support Affects PrEP Use in Black Sexual Minority Individuals Experiencing Discrimination
07/29/2022
Jolynn Tumolo
"While our findings showed some unanticipated relationships, they provide insight into how discrimination and stigma may influence PrEP use and disparities," researchers said.
"While our findings showed some unanticipated relationships, they provide insight into how discrimination and stigma may influence PrEP use and disparities," researchers said.
"While our findings showed some...
07/29/2022
First Report Managed Care

Newsfeed

News
HIV Cases Rise Among Gay Latinos
07/24/2024
Grace Taylor, MS, MA
As HIV rates continue to rise among Latino gay and bisexual men, health policy advocates stress the need for more federal assistance for HIV treatment and prevention in this community.
As HIV rates continue to rise among Latino gay and bisexual men, health policy advocates stress the need for more federal assistance for HIV treatment and prevention in this community.
As HIV rates continue to rise...
07/24/2024
First Report Managed Care
News
Injectable PrEP Overall Acceptable, Preferred for HIV Prevention
07/15/2023
Maria Asimopoulos
“Given overall acceptability, injectable PrEP should be included as part of a menu of prevention options, allowing end-users to select the modality that suits their preferences, needs and lifestyle,” researchers advised.
“Given overall acceptability, injectable PrEP should be included as part of a menu of prevention options, allowing end-users to select the modality that suits their preferences, needs and lifestyle,” researchers advised.
“Given overall acceptability,...
07/15/2023
First Report Managed Care
News
Study Estimates Billable Per Patient Costs of Providing PrEP
12/20/2022
Jolynn Tumolo
Researchers used clinic billing records in Washington, DC and Chicago to estimate the annual billable costs associated with the use of preexposure prophylaxis for HIV.
Researchers used clinic billing records in Washington, DC and Chicago to estimate the annual billable costs associated with the use of preexposure prophylaxis for HIV.
Researchers used clinic billing...
12/20/2022
First Report Managed Care
News
Women View PrEP Services as a Natural Extension of OB/GYN Care
11/17/2022
Jolynn Tumolo
“Multiple participants suggested that initial counseling on PrEP should be offered universally to patients, regardless of sexual history or personal risk factors,” researchers advised.
“Multiple participants suggested that initial counseling on PrEP should be offered universally to patients, regardless of sexual history or personal risk factors,” researchers advised.
“Multiple participants suggested...
11/17/2022
First Report Managed Care
News
Black Sexual Minority Men Report Higher Prevalence of PrEP Use Than White Men
11/14/2022
Jolynn Tumolo
Investigators conducted a survey to determine how prevalent the use of pre- and post-exposure prophylaxis was among over 63,000 participants.
Investigators conducted a survey to determine how prevalent the use of pre- and post-exposure prophylaxis was among over 63,000 participants.
Investigators conducted a survey...
11/14/2022
First Report Managed Care
News
PrEP Most Effective for Reducing HIV Incidence in Men Who Have Sex With Men
11/07/2022
Jolynn Tumolo
Among a variety of interventions, pre-exposure prophylaxis was the only method that showed consistent effectiveness in reducing the incidence of HIV, new findings show.
Among a variety of interventions, pre-exposure prophylaxis was the only method that showed consistent effectiveness in reducing the incidence of HIV, new findings show.
Among a variety of...
11/07/2022
First Report Managed Care
News
Positive Sources of PrEP Awareness Include Partners, Peers, Health Promotions
09/27/2022
Jolynn Tumolo
"Messages from health campaigns were perceived as most positive, and those from religious institutions as least positive," authors said.
"Messages from health campaigns were perceived as most positive, and those from religious institutions as least positive," authors said.
"Messages from health campaigns...
09/27/2022
First Report Managed Care
News
Monitoring HIV Strains to Prevent PrEP Failure, Viral Transmission
09/09/2022
Jolynn Tumolo
Study authors employed a strategy to monitor populations for HIV strains that are resistant to tenofovir and emtricitabine and ensure PrEP failure rates remain rare.
Study authors employed a strategy to monitor populations for HIV strains that are resistant to tenofovir and emtricitabine and ensure PrEP failure rates remain rare.
Study authors employed a...
09/09/2022
First Report Managed Care
News
High Distress in Black MSM Lowers Odds of Antiretroviral Therapy Adherence
09/02/2022
Jolynn Tumolo
High rates of psychological distress may represent an important barrier against HIV treatment adherence for Black men who have sex with men living in urban areas, researchers said.
High rates of psychological distress may represent an important barrier against HIV treatment adherence for Black men who have sex with men living in urban areas, researchers said.
High rates of psychological...
09/02/2022
First Report Managed Care
News
Social Support Affects PrEP Use in Black Sexual Minority Individuals Experiencing Discrimination
07/29/2022
Jolynn Tumolo
"While our findings showed some unanticipated relationships, they provide insight into how discrimination and stigma may influence PrEP use and disparities," researchers said.
"While our findings showed some unanticipated relationships, they provide insight into how discrimination and stigma may influence PrEP use and disparities," researchers said.
"While our findings showed some...
07/29/2022
First Report Managed Care
News
Balancing Clinical Outcomes and Cost: The Value of Biosimilars in Retinal Disease Management
09/26/2025
Juliet Gallagher
A recent study examining the impact of retinal diseases highlights their significant clinical, social, and economic burden.
A recent study examining the impact of retinal diseases highlights their significant clinical, social, and economic burden.
A recent study examining the...
09/26/2025
First Report Managed Care
News
Trump Administration to Test AI-Powered Prior Authorization in Medicare
09/25/2025
Grace Taylor, MS, MA
The Trump administration is set to launch a decade-long Medicare pilot that uses artificial intelligence (AI)-driven prior authorization to curb costs, sparking bipartisan concern over access to care and patient safety.
The Trump administration is set to launch a decade-long Medicare pilot that uses artificial intelligence (AI)-driven prior authorization to curb costs, sparking bipartisan concern over access to care and patient safety.
The Trump administration is set...
09/25/2025
First Report Managed Care
News
Policy Impact: FDA’s Interchangeability Designation Expands Biosimilar Access
09/25/2025
Juliet Gallagher
Insulin glargine, marketed as Semglee and its biosimilar insulin glargine-yfgn, was granted interchangeable status, allowing pharmacists to substitute it for the branded originator without requiring prescriber intervention. A new economic...
Insulin glargine, marketed as Semglee and its biosimilar insulin glargine-yfgn, was granted interchangeable status, allowing pharmacists to substitute it for the branded originator without requiring prescriber intervention. A new economic...
Insulin glargine, marketed as...
09/25/2025
First Report Managed Care
News
How Timing Shapes Biosimilar Success: Insights from US Market Data
09/24/2025
Juliet Gallagher
A recent study published in Value in Health sheds light on the competitive dynamics of biosimilar drugs in the US, specifically examining whether first-mover advantages resemble those seen in generic drug markets.
A recent study published in Value in Health sheds light on the competitive dynamics of biosimilar drugs in the US, specifically examining whether first-mover advantages resemble those seen in generic drug markets.
A recent study published in...
09/24/2025
First Report Managed Care
Hero Image
News
‘First Report Managed Care’ Webinar to Address Specialty Pharmacy Disruption, Cost Pressures, and Patient Access
09/24/2025
Danielle Sposato
Rising specialty drug costs, surging demand for GLP-1 therapies, and ongoing supply chain and policy challenges are putting patient access at risk. To address these pressures, First Report Managed Care will host a complimentary 60-minute...
Rising specialty drug costs, surging demand for GLP-1 therapies, and ongoing supply chain and policy challenges are putting patient access at risk. To address these pressures, First Report Managed Care will host a complimentary 60-minute...
Rising specialty drug costs,...
09/24/2025
First Report Managed Care
News
Biosimilars Match Humira in Structure, Show Greater Stability Under Real-World Stress
09/22/2025
Juliet Gallagher
A new analytical study underscores how advanced nuclear magnetic resonance (NMR) spectroscopy can sharpen head-to-head comparisons between Humira (adalimumab) and its biosimilars—particularly when products are challenged under real-world...
A new analytical study underscores how advanced nuclear magnetic resonance (NMR) spectroscopy can sharpen head-to-head comparisons between Humira (adalimumab) and its biosimilars—particularly when products are challenged under real-world...
A new analytical study...
09/22/2025
First Report Managed Care
News
$3.2 Million Saved Through Biosimilar Substitution in Rheumatology Clinics
09/19/2025
Juliet Gallagher
A study published in the Journal of Clinical Rheumatology found that a recent initiative at a large academic medical center significantly increased biosimilar uptake and generated substantial cost savings through targeted interventions.
A study published in the Journal of Clinical Rheumatology found that a recent initiative at a large academic medical center significantly increased biosimilar uptake and generated substantial cost savings through targeted interventions.
A study published in the Journal...
09/19/2025
First Report Managed Care
News
Pharmacists Lead, Physicians Lag? Provider Perspectives on Biosimilars and Interchangeability
09/18/2025
Juliet Gallagher
A new cross-sectional survey of 249 US outpatient clinicians—150 physicians and 99 pharmacists who treat immunologic conditions—offers a timely snapshot of how front-line decision-makers view biosimilars and the US Food and Drug...
A new cross-sectional survey of 249 US outpatient clinicians—150 physicians and 99 pharmacists who treat immunologic conditions—offers a timely snapshot of how front-line decision-makers view biosimilars and the US Food and Drug...
A new cross-sectional survey of...
09/18/2025
First Report Managed Care
News
Payer-Driven Biosimilar Preferences Create Financial and Operational Strain for Health Systems
09/17/2025
Juliet Gallagher
The expansion of US Food and Drug Administration (FDA)-approved biosimilars has been heralded as a major advancement for lowering healthcare costs in the US, with the potential to reduce both system-wide expenditures and patient out-of-pocket...
The expansion of US Food and Drug Administration (FDA)-approved biosimilars has been heralded as a major advancement for lowering healthcare costs in the US, with the potential to reduce both system-wide expenditures and patient out-of-pocket...
The expansion of US Food and...
09/17/2025
First Report Managed Care
News
DTX101 Gene Therapy Ends Development, Offers Key Lessons for Future Hemophilia B Treatment Strategies
09/16/2025
Grace Taylor, MS, MA
Early-phase trials of the DTX101 gene therapy in hemophilia B showed manageable safety but insufficient efficacy, leading to program discontinuation while offering critical insights for future gene therapy development.
Early-phase trials of the DTX101 gene therapy in hemophilia B showed manageable safety but insufficient efficacy, leading to program discontinuation while offering critical insights for future gene therapy development.
Early-phase trials of the DTX101...
09/16/2025
First Report Managed Care

Insights

Headshot of Brian Mustanski, Northwestern University
Interview
Insurance Coverage, Relationship Status, Other Factors Linked to PrEP Reinitiation
04/14/2022
Maria Asimopoulos
Brian Mustanski, PhD, professor of medical social sciences, Northwestern University, shares factors influencing whether patients reinitiate preexposure prophylaxis for HIV after discontinuation.
Brian Mustanski, PhD, professor of medical social sciences, Northwestern University, shares factors influencing whether patients reinitiate preexposure prophylaxis for HIV after discontinuation.
Brian Mustanski, PhD, professor...
04/14/2022
First Report Managed Care
Chris Beyrer
Podcasts
PrEP in the United States Faces Slow Uptake and Coverage Among Payers
06/30/2021
Julie Gould
Chris Beyrer, MD, infectious disease epidemiologist and professor at Johns Hopkins Bloomberg School of Public Health, breaks down current rates of HIV across the United States as well as the challenges linked with controlling this...
Chris Beyrer, MD, infectious disease epidemiologist and professor at Johns Hopkins Bloomberg School of Public Health, breaks down current rates of HIV across the United States as well as the challenges linked with controlling this...
Chris Beyrer, MD, infectious...
06/30/2021
First Report Managed Care
Addressing Barriers to Preventive HIV Care for At-Risk Patient Populations
Podcasts
Addressing Barriers to Preventive HIV Care for At-Risk Patient Populations
01/25/2021
Ed Pezalla, MD, CEO, Enlightenment Bioconsult LLC, speaks about the barriers to preventive HIV care, pinpoints how payers can reach at-risk populations, and reviews the US Preventive Services Task Force’s measures requiring health plans to...
Ed Pezalla, MD, CEO, Enlightenment Bioconsult LLC, speaks about the barriers to preventive HIV care, pinpoints how payers can reach at-risk populations, and reviews the US Preventive Services Task Force’s measures requiring health plans to...
Ed Pezalla, MD, CEO,...
01/25/2021
First Report Managed Care
Examining a New Class of Antiretroviral Therapy for Patients With Multidrug-Resistant HIV-1 Infection
Videos
Examining a New Class of Antiretroviral Therapy for Patients With Multidrug-Resistant HIV-1 Infection
09/23/2020
Max Lataillade, DO, head of global research strategy, ViiV Healthcare, discusses the findings of the BRIGHTE study that demonstrated a significant decrease in HIV-1 RNA levels among patients treated with fostemsavir, a first-in-class...
Max Lataillade, DO, head of global research strategy, ViiV Healthcare, discusses the findings of the BRIGHTE study that demonstrated a significant decrease in HIV-1 RNA levels among patients treated with fostemsavir, a first-in-class...
Max Lataillade, DO, head of...
09/23/2020
First Report Managed Care

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