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September 2011 - FRMC

Cited Studies on Biomarker Discoveries Prone to Exaggerating Effects
09/19/2011
Christin Melton
Studies are increasingly linking biomarkers to disease risk, treatment response, and disease progression. A recent literature review in the Journal of the American Medical Association [2011;305(21):2200-2207] indicates that some associations...
Studies are increasingly linking biomarkers to disease risk, treatment response, and disease progression. A recent literature review in the Journal of the American Medical Association [2011;305(21):2200-2207] indicates that some associations...
Studies are increasingly linking...
09/19/2011
First Report Managed Care
Telaprevir Improves Outcomes in Some Patients with Hepatitis C
09/19/2011
Christin Melton
Chicago—An analytic model used to calculate long-term outcomes for hypothetical patients with the hepatitis C virus (HCV) projected that patients treated with a combination of telaprevir and peginterferon/ribavirin (PR) would survive between...
Chicago—An analytic model used to calculate long-term outcomes for hypothetical patients with the hepatitis C virus (HCV) projected that patients treated with a combination of telaprevir and peginterferon/ribavirin (PR) would survive between...
Chicago—An analytic model used...
09/19/2011
First Report Managed Care
Linaclotide Significantly Improves Quality of Life and Abdominal Symptoms
09/19/2011
Christin Melton
Trials comparing linaclotide with placebo found that a daily dose reduced the severity of chronic constipation and improveed quality of life. 
Trials comparing linaclotide with placebo found that a daily dose reduced the severity of chronic constipation and improveed quality of life. 
Trials comparing linaclotide...
09/19/2011
First Report Managed Care
Comparing Adjuvant Chemotherapy Regimens in Non–Small-Cell Lung Cancer
09/19/2011
Tim Casey
Chicago—A randomized phase 2 trial found that cisplatin plus pemetrexed was a safe and effective adjuvant chemotherapy regimen for patients with early-stage non–small-cell lung cancer (NSCLC). Patients taking cisplatin plus pemetrexed...
Chicago—A randomized phase 2 trial found that cisplatin plus pemetrexed was a safe and effective adjuvant chemotherapy regimen for patients with early-stage non–small-cell lung cancer (NSCLC). Patients taking cisplatin plus pemetrexed...
Chicago—A randomized phase 2...
09/19/2011
First Report Managed Care
Six-Year Follow-Up of Lenalidomide for Multiple Myeloma
09/19/2011
Tim Casey
Chicago—After 6 years of follow-up in a phase 2 trial, researchers found that a combination therapy of dexamethasone, lenalidomide, and clarithromycin remained an effective regimen for patients who were newly diagnosed with multiple myeloma....
Chicago—After 6 years of follow-up in a phase 2 trial, researchers found that a combination therapy of dexamethasone, lenalidomide, and clarithromycin remained an effective regimen for patients who were newly diagnosed with multiple myeloma....
Chicago—After 6 years of...
09/19/2011
First Report Managed Care
Glucose-Lowering Effect of Insulin Degludec
09/19/2011
Tim Casey
San Diego—In a randomized, double-blind, 2-period, crossover trial, researchers found the glucose-lowering effect of insulin degludec was evenly distributed in the first and second 12-hour periods in patients with type 2 diabetes. They also...
San Diego—In a randomized, double-blind, 2-period, crossover trial, researchers found the glucose-lowering effect of insulin degludec was evenly distributed in the first and second 12-hour periods in patients with type 2 diabetes. They also...
San Diego—In a randomized,...
09/19/2011
First Report Managed Care
Cost of Comorbidities in Obese Adults
09/19/2011
Tim Casey
San Diego—Using data from research databases, researchers confirmed that patients with a body mass index (BMI) ≥35 kg/m2 had a higher prevalence of and costs associated with comorbidities compared with patients who had a BMI between 25 and...
San Diego—Using data from research databases, researchers confirmed that patients with a body mass index (BMI) ≥35 kg/m2 had a higher prevalence of and costs associated with comorbidities compared with patients who had a BMI between 25 and...
San Diego—Using data from...
09/19/2011
First Report Managed Care
Pooled Analysis of Exenatide to Treat Type 2 Diabetes
09/19/2011
Tim Casey
San Diego—A pooled analysis of 16 studies found that patients with type 2 diabetes treated with exenatide twice daily or once weekly had significant improvements in hemoglobin A1c (HbA1c) level, fasting glucose, body weight, and systolic...
San Diego—A pooled analysis of 16 studies found that patients with type 2 diabetes treated with exenatide twice daily or once weekly had significant improvements in hemoglobin A1c (HbA1c) level, fasting glucose, body weight, and systolic...
San Diego—A pooled analysis of...
09/19/2011
First Report Managed Care
Oral Antidiabetics for Type 2 Diabetes and Chronic Kidney Disease
09/19/2011
Tim Casey
San Diego—An examination of electronic health record data from an integrated health system found that patients with type 2 diabetes and chronic kidney disease who had an oral antidiabetic drug regimen concordant with National Kidney...
San Diego—An examination of electronic health record data from an integrated health system found that patients with type 2 diabetes and chronic kidney disease who had an oral antidiabetic drug regimen concordant with National Kidney...
San Diego—An examination of...
09/19/2011
First Report Managed Care
Saxagliptin Safe, Effective after 4 Years
09/19/2011
Tim Casey
San Diego—After examining 4-year extensions of 2 randomized, double-blind, placebo-controlled trials, researchers found that patients with type 2 diabetes who took saxagliptin alone or in combination with metformin tolerated the medication....
San Diego—After examining 4-year extensions of 2 randomized, double-blind, placebo-controlled trials, researchers found that patients with type 2 diabetes who took saxagliptin alone or in combination with metformin tolerated the medication....
San Diego—After examining 4-year...
09/19/2011
First Report Managed Care
Factors Affecting Health Disparities in Diabetes Patients
09/19/2011
Tim Casey
San Diego—After analyzing electronic health records (EHRs) of patients with type 2 diabetes living in the southeast United States, researchers concluded that improving diabetes control and health equity can be achieved through focusing on...
San Diego—After analyzing electronic health records (EHRs) of patients with type 2 diabetes living in the southeast United States, researchers concluded that improving diabetes control and health equity can be achieved through focusing on...
San Diego—After analyzing...
09/19/2011
First Report Managed Care
Effect of Education, Counseling on Diabetes Care
09/19/2011
Tim Casey
San Diego—A retrospective analysis of medical insurance claims data found patients with diabetes who received education and counseling were more likely to have glycemic control and lower diabetes-related healthcare charges compared with those...
San Diego—A retrospective analysis of medical insurance claims data found patients with diabetes who received education and counseling were more likely to have glycemic control and lower diabetes-related healthcare charges compared with those...
San Diego—A retrospective...
09/19/2011
First Report Managed Care
Linagliptin to Treat Type 2 Diabetes Patients with Severe Renal Impairment
09/19/2011
Tim Casey
San Diego—In a randomized, double-blind, placebo-controlled, phase 3 trial of patients with type 2 diabetes and severe renal impairment, researchers found that those who took linagliptin for 12 weeks had a significant reduction in hemoglobin...
San Diego—In a randomized, double-blind, placebo-controlled, phase 3 trial of patients with type 2 diabetes and severe renal impairment, researchers found that those who took linagliptin for 12 weeks had a significant reduction in hemoglobin...
San Diego—In a randomized,...
09/19/2011
First Report Managed Care
Disease Stage and Liraglutide in Type 2 Diabetes
09/19/2011
Tim Casey
San Diego—A pooled analysis of 7 randomized phase 3a and 3b trials found that patients with type 2 diabetes who were treatment naïve or used liraglutide as an add-on therapy to 1 oral antidiabetic agent had a significant reduction in...
San Diego—A pooled analysis of 7 randomized phase 3a and 3b trials found that patients with type 2 diabetes who were treatment naïve or used liraglutide as an add-on therapy to 1 oral antidiabetic agent had a significant reduction in...
San Diego—A pooled analysis of 7...
09/19/2011
First Report Managed Care
More Rigorous Studies Needed to Assess Use of Advanced Access Scheduling in Primary Care
09/19/2011
Christin Melton
An analysis of published English-language studies on advanced access (AA) scheduling in the primary care setting revealed mixed results [Arch Intern Med. 2011;171(13):1150-1159]. Although wait times for an appointment typically decreased, as...
An analysis of published English-language studies on advanced access (AA) scheduling in the primary care setting revealed mixed results [Arch Intern Med. 2011;171(13):1150-1159]. Although wait times for an appointment typically decreased, as...
An analysis of published...
09/19/2011
First Report Managed Care
Spending and Quality in First Year of the Alternative Quality Contract
09/19/2011
Tori Socha
In January 2009, Blue Cross Blue Shield (BCBS) of Massachusetts implemented the Alternative Quality Contract (AQC) payment system. Based on global payment and pay for performance, AQC was implemented in response to continued growth in...
In January 2009, Blue Cross Blue Shield (BCBS) of Massachusetts implemented the Alternative Quality Contract (AQC) payment system. Based on global payment and pay for performance, AQC was implemented in response to continued growth in...
In January 2009, Blue Cross Blue...
09/19/2011
First Report Managed Care
Infections and Cost in Obese Patients Undergoing Colectomy
09/19/2011
Tori Socha
Policymakers utilize rates of surgical site infection (SSI) as a surrogate measure of quality in surgery. Beginning in 2012, hospital SSI rates will be reported to the public. Federal, state, and local pay-for-performance policies are...
Policymakers utilize rates of surgical site infection (SSI) as a surrogate measure of quality in surgery. Beginning in 2012, hospital SSI rates will be reported to the public. Federal, state, and local pay-for-performance policies are...
Policymakers utilize rates of...
09/19/2011
First Report Managed Care
Medicare Part D and Nondrug Medical Spending
09/19/2011
Tori Socha
The Medicare Part D prescription drug benefit has been associated with increased medication use, reduced expenses, and improved patient adherence rates.
The Medicare Part D prescription drug benefit has been associated with increased medication use, reduced expenses, and improved patient adherence rates.
The Medicare Part D prescription...
09/19/2011
First Report Managed Care
Diabetic Kidney Disease in the United States
09/19/2011
Tori Socha
In the developed world, diabetic kidney disease (DKD) is the leading cause of chronic kidney disease. It is estimated that 40% of individuals with diabetes develop DKD, manifested as albuminuria, impaired glomerular filtration rate (GFR), or...
In the developed world, diabetic kidney disease (DKD) is the leading cause of chronic kidney disease. It is estimated that 40% of individuals with diabetes develop DKD, manifested as albuminuria, impaired glomerular filtration rate (GFR), or...
In the developed world, diabetic...
09/19/2011
First Report Managed Care
Most Americans Not Familiar with Parts of ACA Designed to Improve Coverage Access
09/19/2011
The August 2011 tracking poll conducted by the Henry J. Kaiser Family Foundation focused on the opinions of Americans currently without health insurance and the ways they think the Patient Protection and Affordable Care Act (ACA) will affect...
The August 2011 tracking poll conducted by the Henry J. Kaiser Family Foundation focused on the opinions of Americans currently without health insurance and the ways they think the Patient Protection and Affordable Care Act (ACA) will affect...
The August 2011 tracking poll...
09/19/2011
First Report Managed Care
Study Examines Cost-Shifting and MedPAC Perspectives on Hospital Pricing, Profitability
09/19/2011
Tim Casey
A recent analysis of 7 common procedures found that hospitals’ contribution margins were 831% higher when treating patients covered by private health insurance compared with Medicare patients. The results also indicated that in 4 of the...
A recent analysis of 7 common procedures found that hospitals’ contribution margins were 831% higher when treating patients covered by private health insurance compared with Medicare patients. The results also indicated that in 4 of the...
A recent analysis of 7 common...
09/19/2011
First Report Managed Care
Drug Shortages Cause Concern for Healthcare Industry
09/19/2011
Tim Casey
Since 1968, Michael Cohen has worked as a pharmacist, focusing on helping patients and ensuring he is providing safe and effective therapies. Mr. Cohen is now president of the Institute for Safe Medication Practices, a nonprofit...
Since 1968, Michael Cohen has worked as a pharmacist, focusing on helping patients and ensuring he is providing safe and effective therapies. Mr. Cohen is now president of the Institute for Safe Medication Practices, a nonprofit...
Since 1968, Michael Cohen has...
09/19/2011
First Report Managed Care

Behind the Bill

Behind the Bill
The Senate’s $3 Trillion Deal. Tax Relief Now, Medicaid Coverage Loss Later?
07/02/2025
Katie Hayes, MJ
The Senate has done it. After weeks of behind-the-scenes wrangling and last-minute amendments, lawmakers have passed a sprawling tax-and-spending megabill that makes good on a long-standing Republican goal: making the 2017 Trump tax cuts...
The Senate has done it. After weeks of behind-the-scenes wrangling and last-minute amendments, lawmakers have passed a sprawling tax-and-spending megabill that makes good on a long-standing Republican goal: making the 2017 Trump tax cuts...
The Senate has done it. After...
07/02/2025
First Report Managed Care
Behind the Bill
When a Cap Isn’t Just a Cap: How a Provider Tax Proposal Could Reshape Medicaid Financing
06/25/2025
Katie Hayes, MJ
In Washington, the most consequential policies are often buried in the fine print. One such detail in the Senate Finance Committee’s latest tax and spending proposal would gradually cap provider taxes—a core funding tool states use to pull in...
In Washington, the most consequential policies are often buried in the fine print. One such detail in the Senate Finance Committee’s latest tax and spending proposal would gradually cap provider taxes—a core funding tool states use to pull in...
In Washington, the most...
06/25/2025
First Report Managed Care
Behind the Bill
Rewriting the Safety Net? Inside the Senate’s Changes to Medicaid and the ACA
06/18/2025
Katie Hayes, MJ
Over the past few weeks, I’ve been following the progress of the One Big Beautiful Bill Act (OBBBA), which started in the House with sweeping tax reforms and some eye-catching health care proposals. Now, the Senate has released its (highly...
Over the past few weeks, I’ve been following the progress of the One Big Beautiful Bill Act (OBBBA), which started in the House with sweeping tax reforms and some eye-catching health care proposals. Now, the Senate has released its (highly...
Over the past few weeks, I’ve...
06/18/2025
First Report Managed Care
Behind the Bill
How States Might Respond to the One Big Beautiful Bill Act
06/11/2025
Katie Hayes, MJ
With the One Big Beautiful Bill Act (OBBBA) still in the hands of the Senate, much of the national conversation has centered on what this legislation would do to federal coverage programs. But regardless of how the federal process unfolds,...
With the One Big Beautiful Bill Act (OBBBA) still in the hands of the Senate, much of the national conversation has centered on what this legislation would do to federal coverage programs. But regardless of how the federal process unfolds,...
With the One Big Beautiful Bill...
06/11/2025
First Report Managed Care
Behind the Bill
Is the Affordable Care Act on the Chopping Block? What the One Big Beautiful Bill Act Tells Us.
06/04/2025
Katie Hayes, MJ
It’s been weeks of headline-grabbing debate over Medicaid work requirements, and the “One Big Beautiful Bill Act” remains in the Senate as they deliberate over several health care provisions. While the Medicaid provisions sparked most of the...
It’s been weeks of headline-grabbing debate over Medicaid work requirements, and the “One Big Beautiful Bill Act” remains in the Senate as they deliberate over several health care provisions. While the Medicaid provisions sparked most of the...
It’s been weeks of...
06/04/2025
First Report Managed Care
Behind the Bill
From House to Senate: The Journey of Cutting Medicaid
05/28/2025
Katie Hayes, MJ
Last week, the House of Representatives narrowly passed the One Big Beautiful Bill Act (HR 1, 119th Congress) by a single vote, sending the sweeping tax and spending reconciliation package, backed by President Trump, to the Senate. With its...
Last week, the House of Representatives narrowly passed the One Big Beautiful Bill Act (HR 1, 119th Congress) by a single vote, sending the sweeping tax and spending reconciliation package, backed by President Trump, to the Senate. With its...
Last week, the House of...
05/28/2025
First Report Managed Care
Behind the Bill
Eligibility, Paperwork, and Penalties: The Not-So-Hidden Costs of Medicaid ‘Reform’
05/21/2025
Katie Hayes, MJ
It’s been another eventful week in health policy—a phrase that’s quickly becoming routine. This time, House Republicans advanced a sweeping budget reconciliation bill, designed to implement elements of the March budget resolution, with a...
It’s been another eventful week in health policy—a phrase that’s quickly becoming routine. This time, House Republicans advanced a sweeping budget reconciliation bill, designed to implement elements of the March budget resolution, with a...
It’s been another eventful week...
05/21/2025
First Report Managed Care
Behind the Bill
A Busy Week in Drug Pricing Policy: Aligning US Drug Prices With Global Standards?
05/14/2025
Katie Hayes, MJ
It’s been a busy few days for drug pricing policy. While I’d love to dig into the details of both President Trump’s latest executive order and the newest Republican bill that would cut Medicaid spending, we don’t have the time—and this isn’t...
It’s been a busy few days for drug pricing policy. While I’d love to dig into the details of both President Trump’s latest executive order and the newest Republican bill that would cut Medicaid spending, we don’t have the time—and this isn’t...
It’s been a busy few days for...
05/14/2025
First Report Managed Care
BEHIND THE BILL
When Agencies Lose Power: How 3 Seismic Shifts are Transforming Pharmaceutical Regulation
05/07/2025
Katie Hayes, MJ
In the span of just 9 months, the landscape of administrative law has undergone a transformation so profound that pharmaceutical executives, health care providers, and patients alike are struggling to navigate the new terrain. The Supreme...
In the span of just 9 months, the landscape of administrative law has undergone a transformation so profound that pharmaceutical executives, health care providers, and patients alike are struggling to navigate the new terrain. The Supreme...
In the span of just 9 months,...
05/07/2025
First Report Managed Care
Behind the Bill
The Medicare Paradox, Part 3: Strategic Trade Doesn’t Have to be a Zero-Sum Game
05/07/2025
Katie Hayes, MJ
Over the past 2 weeks, I’ve examined the growing friction between the Section 232 pharmaceutical tariff investigations and the Medicare drug pricing reforms authorized by the Inflation Reduction Act (IRA). These 2 policy agendas—industrial...
Over the past 2 weeks, I’ve examined the growing friction between the Section 232 pharmaceutical tariff investigations and the Medicare drug pricing reforms authorized by the Inflation Reduction Act (IRA). These 2 policy agendas—industrial...
Over the past 2 weeks, I’ve...
05/07/2025
First Report Managed Care

Trending Articles

News
Who Will Benefit Under the Medicare Part D Out-of-Pocket Spending Cap?
02/27/2024
Dean Celia
Starting in 2024, Medicare Part D enrollees could benefit from a cap placed on out-of-pocket drug spending, thanks to a provision in the Inflation Reduction Act of 2022 (IRA).
Starting in 2024, Medicare Part D enrollees could benefit from a cap placed on out-of-pocket drug spending, thanks to a provision in the Inflation Reduction Act of 2022 (IRA).
Starting in 2024, Medicare Part...
02/27/2024
First Report Managed Care
News
The Impact of Inhibitors on Surgical Management in Patients With Hemophilia
04/04/2024
Hannah Musick
The development of inhibitors in patients with hemophilia poses challenges for achieving perioperative hemostasis and may result in complications and deviations from the surgical plan, highlighting the need for strategies to address inhibitor...
The development of inhibitors in patients with hemophilia poses challenges for achieving perioperative hemostasis and may result in complications and deviations from the surgical plan, highlighting the need for strategies to address inhibitor...
The development of inhibitors in...
04/04/2024
First Report Managed Care
Conference Coverage
Expanding Pharmacists’ Role in Providing Clinical Care: Addressing Public Health Challenges
05/02/2024
Danielle Sposato
Panelists from various backgrounds discuss the critical role of pharmacists in addressing public health challenges such as HIV/AIDS and advocating for expanded clinical care and reimbursement pathways to improve health outcomes in communities.
Panelists from various backgrounds discuss the critical role of pharmacists in addressing public health challenges such as HIV/AIDS and advocating for expanded clinical care and reimbursement pathways to improve health outcomes in communities.
Panelists from various...
05/02/2024
First Report Managed Care
Managed Care Q&A
Prioritizing Patient Voices in Drug Development and Coverage
05/27/2024
In this interview, guest experts discuss the importance of incorporating patient voices into health care decision-making, highlighting opportunities for collaboration and enhancement in drug development and patient coverage.
In this interview, guest experts discuss the importance of incorporating patient voices into health care decision-making, highlighting opportunities for collaboration and enhancement in drug development and patient coverage.
In this interview, guest experts...
05/27/2024
First Report Managed Care
Blog
The Clash Over Medicare: Key Lawsuits Challenging the IRA’s Drug Negotiation Provisions
07/11/2024
Katie Hayes, MJ
The IRA has spawned a series of lawsuits from pharmaceutical companies. Here, we provide the latest status updates on several of them.
The IRA has spawned a series of lawsuits from pharmaceutical companies. Here, we provide the latest status updates on several of them.
The IRA has spawned a series of...
07/11/2024
First Report Managed Care

September 2011 Volume 8 Issue 9

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