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March 2011 - FRMC

News Connection
03/21/2011
Eileen Koutnik-Fotopoulos
Rare variants of genes involved in idiopathic hypogonadotropic hypogonadism contribute to the occurrence of functional hypothalamic amenorrhea in some women. 
Rare variants of genes involved in idiopathic hypogonadotropic hypogonadism contribute to the occurrence of functional hypothalamic amenorrhea in some women. 
Rare variants of genes involved...
03/21/2011
First Report Managed Care
Conference Insider
03/21/2011
Kevin L. Carter
Although the incidence of surgical site infections (SSIs) after cardiothoracic (CT) surgery is relatively low, these infections can carry significant morbidity and mortality and can incur substantial costs. The overall incidence of serious...
Although the incidence of surgical site infections (SSIs) after cardiothoracic (CT) surgery is relatively low, these infections can carry significant morbidity and mortality and can incur substantial costs. The overall incidence of serious...
Although the incidence of...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Sylvia Jenkins
Based on clinical and randomized controlled trials, practice guidelines for implantable cardioverter-defibrillator (ICD) therapy for primary prevention were established in 2006 and 2008. A 40-day period following a myocardial infarction (MI)...
Based on clinical and randomized controlled trials, practice guidelines for implantable cardioverter-defibrillator (ICD) therapy for primary prevention were established in 2006 and 2008. A 40-day period following a myocardial infarction (MI)...
Based on clinical and randomized...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Tori Socha
Patients with heart failure require rehospitalization at a high rate, creating a need to develop strategies to improve outcomes in these patients.
Patients with heart failure require rehospitalization at a high rate, creating a need to develop strategies to improve outcomes in these patients.
Patients with heart failure...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Tori Socha
Primary care clinicians are caring for an increasing number of older patients who have multiple diseases and conditions. Providing optimal care for these patients is a complex task, made more difficult by seemingly contradictory evidence of...
Primary care clinicians are caring for an increasing number of older patients who have multiple diseases and conditions. Providing optimal care for these patients is a complex task, made more difficult by seemingly contradictory evidence of...
Primary care clinicians are...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Jill Sederstorm
A new study of angiographic patency for male patients undergoing first-time elective coronary artery bypass grafting (CABG) found no difference in 1-year patency for those who had radial artery grafts compared with those who received...
A new study of angiographic patency for male patients undergoing first-time elective coronary artery bypass grafting (CABG) found no difference in 1-year patency for those who had radial artery grafts compared with those who received...
A new study of angiographic...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Kerri Fitzgerald
In a head-to-head study, researchers found that compared with losartan, candesartan is associated with lower all-cause mortality in patients with heart failure (HF). In a study presented in the Journal of the American Medical Association...
In a head-to-head study, researchers found that compared with losartan, candesartan is associated with lower all-cause mortality in patients with heart failure (HF). In a study presented in the Journal of the American Medical Association...
In a head-to-head study,...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Kristina Woodworth
A placebo-controlled study has found that eplerenone, a selective mineralocorticoid-receptor antagonist, reduced the risk of both cardiovascular-related death and heart failure hospitalizations in patients with chronic systolic heart failure...
A placebo-controlled study has found that eplerenone, a selective mineralocorticoid-receptor antagonist, reduced the risk of both cardiovascular-related death and heart failure hospitalizations in patients with chronic systolic heart failure...
A placebo-controlled study has...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Tori Socha
Clinical practice guidelines have been developed to help clinicians improve patient outcomes and to streamline delivery of healthcare by analyzing and summarizing data from relevant publications. 
Clinical practice guidelines have been developed to help clinicians improve patient outcomes and to streamline delivery of healthcare by analyzing and summarizing data from relevant publications. 
Clinical practice guidelines...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Tori Socha
Although it is standard practice for medical journals to require authors to disclose industry relationships, the requirements vary among journals and are often not specific, according to researchers. 
Although it is standard practice for medical journals to require authors to disclose industry relationships, the requirements vary among journals and are often not specific, according to researchers. 
Although it is standard practice...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Jill Sederstorm
Men with postoperative incontinence issues persisting at least 1 year after receiving a radical prostatectomy were found to have fewer incontinence episodes after 8 weeks of behavioral therapy when compared with a control group; however,...
Men with postoperative incontinence issues persisting at least 1 year after receiving a radical prostatectomy were found to have fewer incontinence episodes after 8 weeks of behavioral therapy when compared with a control group; however,...
Men with postoperative...
03/21/2011
First Report Managed Care
Conference Insider
03/21/2011
Tori Socha
In patients undergoing major abdominal surgery, optimal perioperative fluid management remains challenging, according to researchers. Adequate tissue perfusion is an essential component of oxygenation and can improve postoperative outcomes....
In patients undergoing major abdominal surgery, optimal perioperative fluid management remains challenging, according to researchers. Adequate tissue perfusion is an essential component of oxygenation and can improve postoperative outcomes....
In patients undergoing major...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Tori Socha
Treatment and monitoring of patients with multiple sclerosis (MS) made important strides in 2010, according to a review in Nature [2011;7:74-75]. Magnetic resonance imaging (MRI) and immunologic biomarkers were identified to track the...
Treatment and monitoring of patients with multiple sclerosis (MS) made important strides in 2010, according to a review in Nature [2011;7:74-75]. Magnetic resonance imaging (MRI) and immunologic biomarkers were identified to track the...
Treatment and monitoring of...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Tori Socha
The median age at onset of multiple sclerosis (MS) is approximately 30 years. Initially, the disease is often characterized by relapses and remissions, followed by a progressive worsening of neurologic function (secondary progressive MS). In...
The median age at onset of multiple sclerosis (MS) is approximately 30 years. Initially, the disease is often characterized by relapses and remissions, followed by a progressive worsening of neurologic function (secondary progressive MS). In...
The median age at onset of...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Tori Socha
Disease-modifying drugs currently available for the treatment of multiple sclerosis (MS), including various formulations of interferon beta (IFNβ ), glatiramer acetate, natalizumab, and mitoxantrone, require parenteral administration....
Disease-modifying drugs currently available for the treatment of multiple sclerosis (MS), including various formulations of interferon beta (IFNβ ), glatiramer acetate, natalizumab, and mitoxantrone, require parenteral administration....
Disease-modifying drugs...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Tori Socha
Multiple sclerosis (MS) is a chronic and disabling disease of the central nervous system that affects nearly 400,000 Americans; approximately 200 people receive a diagnosis of MS each week. Worldwide, the number of people with the disease is...
Multiple sclerosis (MS) is a chronic and disabling disease of the central nervous system that affects nearly 400,000 Americans; approximately 200 people receive a diagnosis of MS each week. Worldwide, the number of people with the disease is...
Multiple sclerosis (MS) is a...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Mary Beth Nierengarten
Results of a multicenter, randomized, double-blind trial [Arch Intern Med. 2010;170 (22):2021-2027] show that the adrenergic alpha-blocker tamsulosin did not accelerate the expulsion of distal ureteral stones in patients with renal colic.
Results of a multicenter, randomized, double-blind trial [Arch Intern Med. 2010;170 (22):2021-2027] show that the adrenergic alpha-blocker tamsulosin did not accelerate the expulsion of distal ureteral stones in patients with renal colic.
Results of a multicenter,...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Mary Beth Nierengarten
Results of two phase 3, double-blind, placebo-controlled, randomized clinical trials [N Engl J Med. 2011;364(1):22-32] show that patients with irritable bowel syndrome (IBS) treated with rifaximin for 2 weeks had significant improvements for...
Results of two phase 3, double-blind, placebo-controlled, randomized clinical trials [N Engl J Med. 2011;364(1):22-32] show that patients with irritable bowel syndrome (IBS) treated with rifaximin for 2 weeks had significant improvements for...
Results of two phase 3,...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Mary Beth Nierengarten
Results of a descriptive study of the top-selling 200 pediatric OTC medications on the market during 52 weeks found high levels of variability and inconsistency in dosing directions and measuring devices.
Results of a descriptive study of the top-selling 200 pediatric OTC medications on the market during 52 weeks found high levels of variability and inconsistency in dosing directions and measuring devices.
Results of a descriptive study...
03/21/2011
First Report Managed Care
News Connection
03/21/2011
Kerri Fitzgerald
In 2009, the number of uninsured reached 50 million people nationwide. The 2010 Patient Protection and Affordable Care Act was designed to decrease the number of uninsured individuals by providing Medicaid or subsidizing coverage to...
In 2009, the number of uninsured reached 50 million people nationwide. The 2010 Patient Protection and Affordable Care Act was designed to decrease the number of uninsured individuals by providing Medicaid or subsidizing coverage to...
In 2009, the number of uninsured...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Kevin L. Carter
The most common cause of death among patients with type 2 diabetes mellitus is cardiovascular disease. While progress has been made in establishing preventive care among this population, there is still an excess of deaths associated with...
The most common cause of death among patients with type 2 diabetes mellitus is cardiovascular disease. While progress has been made in establishing preventive care among this population, there is still an excess of deaths associated with...
The most common cause of death...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Tori Socha
For patients with cardiovascular disease, standard of care is dual antiplatelet therapy (DAT) with clopidogrel plus aspirin.
For patients with cardiovascular disease, standard of care is dual antiplatelet therapy (DAT) with clopidogrel plus aspirin.
For patients with cardiovascular...
03/21/2011
First Report Managed Care
Feature
03/21/2011
Tori Socha
More than 10% of the adults in the United States have diabetes; in those aged ≥60 years of age, the prevalence is 23%. Approximately 14.8 million Americans aged ≥18 years are affected by major depressive disorder (MDD) in a given year. The...
More than 10% of the adults in the United States have diabetes; in those aged ≥60 years of age, the prevalence is 23%. Approximately 14.8 million Americans aged ≥18 years are affected by major depressive disorder (MDD) in a given year. The...
More than 10% of the adults in...
03/21/2011
First Report Managed Care
News Connection
03/18/2011
The most recent Kaiser Family Foundation health tracking poll, conducted in the wake of the healthcare reform repeal vote in the US House of Representatives, found that 22% of Americans believe that the Patient Protection and Affordable Care...
The most recent Kaiser Family Foundation health tracking poll, conducted in the wake of the healthcare reform repeal vote in the US House of Representatives, found that 22% of Americans believe that the Patient Protection and Affordable Care...
The most recent Kaiser Family...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—Between 2001 and 2006 the number of patients in the Medicare population receiving Mohs micrographic surgery (MMS) for nonmelanoma skin cancer (NMSC) doubled, according to a retrospective review of Medicare patients receiving...
New Orleans—Between 2001 and 2006 the number of patients in the Medicare population receiving Mohs micrographic surgery (MMS) for nonmelanoma skin cancer (NMSC) doubled, according to a retrospective review of Medicare patients receiving...
New Orleans—Between 2001 and...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—According to an analysis of the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) program from 1973 through 2006, patients with regressing melanoma had a higher survival rate than those with...
New Orleans—According to an analysis of the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) program from 1973 through 2006, patients with regressing melanoma had a higher survival rate than those with...
New Orleans—According to an...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—A pooled analysis of three phase 3, randomized, double-blind, placebo-controlled trials of patients with moderate-to-severe psoriasis found that patients taking briakinumab had superior results to those taking placebo as measured...
New Orleans—A pooled analysis of three phase 3, randomized, double-blind, placebo-controlled trials of patients with moderate-to-severe psoriasis found that patients taking briakinumab had superior results to those taking placebo as measured...
New Orleans—A pooled analysis of...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—A 12-week, double-blind, placebo-controlled, phase 2b study found that patients with psoriasis who took tofacitinib had sustained clinically meaningful improvement in pruritus severity. Carla Mamolo, PhD, associate director of...
New Orleans—A 12-week, double-blind, placebo-controlled, phase 2b study found that patients with psoriasis who took tofacitinib had sustained clinically meaningful improvement in pruritus severity. Carla Mamolo, PhD, associate director of...
New Orleans—A 12-week,...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—An analysis of adult patients with moderate-to-severe psoriasis found that those treated with adalimumab had significantly fewer medical services and significantly lower pharmacy costs and medical services costs compared with...
New Orleans—An analysis of adult patients with moderate-to-severe psoriasis found that those treated with adalimumab had significantly fewer medical services and significantly lower pharmacy costs and medical services costs compared with...
New Orleans—An analysis of adult...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—Patients taking ustekinumab for ≤3 years had similar rates of serious and nonserious cardiovascular (CV) events compared with a placebo group, according to a pooled analysis of phase 2 and 3 trials. Kenneth B. Gordon, MD, medical...
New Orleans—Patients taking ustekinumab for ≤3 years had similar rates of serious and nonserious cardiovascular (CV) events compared with a placebo group, according to a pooled analysis of phase 2 and 3 trials. Kenneth B. Gordon, MD, medical...
New Orleans—Patients taking...
03/18/2011
First Report Managed Care
Conference Insider
03/18/2011
Tim Casey
As part of the Patient Protection and Affordable Care Act (HR 3590), healthcare providers will be held more responsible for their quality of care and adherence to information technology initiatives such as quality reporting and electronic...
As part of the Patient Protection and Affordable Care Act (HR 3590), healthcare providers will be held more responsible for their quality of care and adherence to information technology initiatives such as quality reporting and electronic...
As part of the Patient...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—In a retrospective cohort study of 97 patients with Sézary syndrome receiving multiple immune-modifying therapies, the following factors were strongest for predicting complete response to treatment compared with no response: lower...
New Orleans—In a retrospective cohort study of 97 patients with Sézary syndrome receiving multiple immune-modifying therapies, the following factors were strongest for predicting complete response to treatment compared with no response: lower...
New Orleans—In a retrospective...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—A large retrospective cohort study found that taking tumor necrosis factor (TNF) inhibitors to treat psoriasis was associated with a significant reduction in the risk of myocardial infarction (MI) compared with not taking TNF...
New Orleans—A large retrospective cohort study found that taking tumor necrosis factor (TNF) inhibitors to treat psoriasis was associated with a significant reduction in the risk of myocardial infarction (MI) compared with not taking TNF...
New Orleans—A large...
03/18/2011
First Report Managed Care
Feature
03/18/2011
Tim Casey
New Orleans—According to a database analysis study, there were an estimated 3.7 million cases of nonmelanoma skin cancer (NMSC) in the United States in 2009. The disease cost the government $8.6 billion in 2008, and that estimate may be low...
New Orleans—According to a database analysis study, there were an estimated 3.7 million cases of nonmelanoma skin cancer (NMSC) in the United States in 2009. The disease cost the government $8.6 billion in 2008, and that estimate may be low...
New Orleans—According to a...
03/18/2011
First Report Managed Care
News Connection
03/18/2011
Tim Casey
Although health spending in the United States in 2009 increased at the slowest rate in 50 years, the percentage of US gross domestic product (GDP) devoted to healthcare was the highest in the history of the National Health Expenditure (NHE)...
Although health spending in the United States in 2009 increased at the slowest rate in 50 years, the percentage of US gross domestic product (GDP) devoted to healthcare was the highest in the history of the National Health Expenditure (NHE)...
Although health spending in the...
03/18/2011
First Report Managed Care
Department
03/18/2011
Tim Casey
The FDA approved 21 drugs in 2010, down from 26 in 2009 and 24 in 2008. Last year’s total included 15 new molecular entities and 6 biologics.
The FDA approved 21 drugs in 2010, down from 26 in 2009 and 24 in 2008. Last year’s total included 15 new molecular entities and 6 biologics.
The FDA approved 21 drugs in...
03/18/2011
First Report Managed Care