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June 2014 - FRMC

06/19/2014
Tim Casey
Tampa—Within the next 5 years, specialty pharmaceuticals are expected to account for more than half of the overall drug spending in the United States. By 2016, 8 of the top 10 branded drugs will be specialty medications, while 53 specialty...
Tampa—Within the next 5 years, specialty pharmaceuticals are expected to account for more than half of the overall drug spending in the United States. By 2016, 8 of the top 10 branded drugs will be specialty medications, while 53 specialty...
Tampa—Within the next 5 years,...
06/19/2014
First Report Managed Care
06/19/2014
Tim Casey
The FDA approved oral medications—sofosbuvir and simeprevir—to treat hepatitis C.
The FDA approved oral medications—sofosbuvir and simeprevir—to treat hepatitis C.
The FDA approved oral...
06/19/2014
First Report Managed Care
06/19/2014
Kerri Fitzgerald
Tampa—Approximately 74% of patients with schizophrenia are nonadherent to oral antipsychotic medications. Even short treatment gaps with oral antipsychotics are associated with increased relapse risk, and 80% of patients with schizophrenia...
Tampa—Approximately 74% of patients with schizophrenia are nonadherent to oral antipsychotic medications. Even short treatment gaps with oral antipsychotics are associated with increased relapse risk, and 80% of patients with schizophrenia...
Tampa—Approximately 74% of...
06/19/2014
First Report Managed Care
06/19/2014
Tim Casey
Orlando—In the United States, half of the 24 million people with chronic obstructive pulmonary disease (COPD) are undiagnosed. Still, a person dies from COPD every 4 minutes. The disease is the fourth leading cause of death and will be the...
Orlando—In the United States, half of the 24 million people with chronic obstructive pulmonary disease (COPD) are undiagnosed. Still, a person dies from COPD every 4 minutes. The disease is the fourth leading cause of death and will be the...
Orlando—In the United States,...
06/19/2014
First Report Managed Care
06/19/2014
Tim Casey
According to the Centers for Disease Control and Prevention, 34.9% of adults in the United States are obese, while the estimated obesity-related costs are $147 billion per year.
According to the Centers for Disease Control and Prevention, 34.9% of adults in the United States are obese, while the estimated obesity-related costs are $147 billion per year.
According to the Centers for...
06/19/2014
First Report Managed Care
06/19/2014
Tim Casey
Orlando—A 2011 report from the Institute of Medicine (IOM) found that chronic pain affects 116 million people in the United States, more than the total affected by heart disease, cancer, and diabetes combined. The disease also costs the...
Orlando—A 2011 report from the Institute of Medicine (IOM) found that chronic pain affects 116 million people in the United States, more than the total affected by heart disease, cancer, and diabetes combined. The disease also costs the...
Orlando—A 2011 report from the...
06/19/2014
First Report Managed Care
06/19/2014
Tim Casey
San Diego—Patients with chronic obstructive pulmonary disease (COPD) who also had mild and moderate liver impairment or severe renal impairment tolerated a single orally-inhaled dose of olodaterol, according to 2 single-center, open-label...
San Diego—Patients with chronic obstructive pulmonary disease (COPD) who also had mild and moderate liver impairment or severe renal impairment tolerated a single orally-inhaled dose of olodaterol, according to 2 single-center, open-label...
San Diego—Patients with chronic...
06/19/2014
First Report Managed Care
06/19/2014
Tim Casey
San Diego—Patients with idiopathic pulmonary fibrosis (IPF) who received 150 mg of nintedanib twice daily had a significant reduction in the rate of decline of forced vital capacity (FVC) compared with a placebo group, according to 2 phase 3,...
San Diego—Patients with idiopathic pulmonary fibrosis (IPF) who received 150 mg of nintedanib twice daily had a significant reduction in the rate of decline of forced vital capacity (FVC) compared with a placebo group, according to 2 phase 3,...
San Diego—Patients with...
06/19/2014
First Report Managed Care
06/19/2014
Mary Mihalovic
A recent study has shown that an 8-week regimen consisting of the antiviral agents ledipasvir and sofosbuvir was just as effective as a 12-week regimen in previously untreated patients with hepatitis C without cirrhosis [N Engl J Med. DOI:...
A recent study has shown that an 8-week regimen consisting of the antiviral agents ledipasvir and sofosbuvir was just as effective as a 12-week regimen in previously untreated patients with hepatitis C without cirrhosis [N Engl J Med. DOI:...
A recent study has shown that an...
06/19/2014
First Report Managed Care
06/19/2014
Mary Mihalovic
Combination treatment of ritonavir-enhanced ABT-450 with ombitasvir, dasabuvir, and ribavirin was shown to be effective in both previously treated and untreated patients with hepatitis C and compensated cirrhosis, according to a recent study...
Combination treatment of ritonavir-enhanced ABT-450 with ombitasvir, dasabuvir, and ribavirin was shown to be effective in both previously treated and untreated patients with hepatitis C and compensated cirrhosis, according to a recent study...
Combination treatment of...
06/19/2014
First Report Managed Care
06/19/2014
Mary Mihalovic
A 12-week, single-tablet regimen consisting of the nucleotide polymerase inhibitor, sofosbuvir, and the NS5A inhibitor, ledipasvir, was shown to be highly effective in previously untreated patients with hepatitis C genotype 1, according to...
A 12-week, single-tablet regimen consisting of the nucleotide polymerase inhibitor, sofosbuvir, and the NS5A inhibitor, ledipasvir, was shown to be highly effective in previously untreated patients with hepatitis C genotype 1, according to...
A 12-week, single-tablet regimen...
06/19/2014
First Report Managed Care
06/19/2014
Kerri Fitzgerald
Commonly, interstitial pneumonia (IP) complicates collagen vascular disease (CVD) and IP may be the first or only manifestation of CVD. It is difficult to distinguish IP from CVD and many patients may be diagnosed with idiopathic IP....
Commonly, interstitial pneumonia (IP) complicates collagen vascular disease (CVD) and IP may be the first or only manifestation of CVD. It is difficult to distinguish IP from CVD and many patients may be diagnosed with idiopathic IP....
Commonly, interstitial pneumonia...
06/19/2014
First Report Managed Care
06/19/2014
Kerri Fitzgerald
Previous studies have suggested that acetylcysteine is a beneficial treatment for idiopathic pulmonary fibrosis (IPF); however, data from placebo-controlled trials are lacking. A recent study by the Idiopathic Pulmonary Fibrosis Clinical...
Previous studies have suggested that acetylcysteine is a beneficial treatment for idiopathic pulmonary fibrosis (IPF); however, data from placebo-controlled trials are lacking. A recent study by the Idiopathic Pulmonary Fibrosis Clinical...
Previous studies have suggested...
06/19/2014
First Report Managed Care
06/19/2014
Kerri Fitzgerald
Two previous phase 3 trials have found that pirfenidone reduced disease progression in patients with idiopathic pulmonary fibrosis (IPF), as measured by the decline in forced vital capacity (FVC) or vital capacity. However, another phase 3...
Two previous phase 3 trials have found that pirfenidone reduced disease progression in patients with idiopathic pulmonary fibrosis (IPF), as measured by the decline in forced vital capacity (FVC) or vital capacity. However, another phase 3...
Two previous phase 3 trials have...
06/19/2014
First Report Managed Care
06/19/2014
Kerri Fitzgerald
Chronic obstructive pulmonary disease (COPD) is associated with annual direct costs of $29.5 billion. COPD exacerbations are the key drivers of the healthcare costs, accounting for approximately 70%. Comorbid chronic conditions among COPD...
Chronic obstructive pulmonary disease (COPD) is associated with annual direct costs of $29.5 billion. COPD exacerbations are the key drivers of the healthcare costs, accounting for approximately 70%. Comorbid chronic conditions among COPD...
Chronic obstructive pulmonary...
06/19/2014
First Report Managed Care
06/19/2014
Melissa D. Cooper
There are an estimated 15 million Medicare beneficiaries using retiree health benefit plans as supplemental coverage. An additional >2 million pre-retirees are also using retiree health benefit plans as a primary source of coverage, making...
There are an estimated 15 million Medicare beneficiaries using retiree health benefit plans as supplemental coverage. An additional >2 million pre-retirees are also using retiree health benefit plans as a primary source of coverage, making...
There are an estimated 15...
06/19/2014
First Report Managed Care
06/18/2014
Sarah O'Brien
The expansion of prescription opioids among adults >65 years of age may be an indication of a fragmented healthcare system, in which patients receive opioids from multiple physicians who do not or cannot communicate with one another,...
The expansion of prescription opioids among adults >65 years of age may be an indication of a fragmented healthcare system, in which patients receive opioids from multiple physicians who do not or cannot communicate with one another,...
The expansion of prescription...
06/18/2014
First Report Managed Care
06/18/2014
Kerri Fitzgerald
Studies have shown that diabetes is a chronic physical health condition often linked with symptoms of depression. Comorbid depression and diabetes can significantly worsen patient self-care, health, and economic burden of diabetes. The...
Studies have shown that diabetes is a chronic physical health condition often linked with symptoms of depression. Comorbid depression and diabetes can significantly worsen patient self-care, health, and economic burden of diabetes. The...
Studies have shown that diabetes...
06/18/2014
First Report Managed Care
06/18/2014
Mary Beth Nierengarten
The results of a model-based health economic study showed that the use of aclidinium bromide as maintenance treatment of moderate-to-severe chronic obstructive pulmonary disease (COPD) may be more cost-effective than tiotropium bromide...
The results of a model-based health economic study showed that the use of aclidinium bromide as maintenance treatment of moderate-to-severe chronic obstructive pulmonary disease (COPD) may be more cost-effective than tiotropium bromide...
The results of a model-based...
06/18/2014
First Report Managed Care
06/18/2014
Sarah O'Brien
Prior to electronic health records (EHRs), educational materials for patients were primarily handouts and pamphlets.
Prior to electronic health records (EHRs), educational materials for patients were primarily handouts and pamphlets.
Prior to electronic health...
06/18/2014
First Report Managed Care
06/18/2014
Eileen Koutnik-Fotopoulos
Results from the DESCARTES (Durable Effect of PCSK9 Antibody Compared with Placebo Study) trial found that the investigational PCSK9 inhibitor, evolocumab, for the treatment of hyperlipidemia significantly reduced low-density lipoprotein...
Results from the DESCARTES (Durable Effect of PCSK9 Antibody Compared with Placebo Study) trial found that the investigational PCSK9 inhibitor, evolocumab, for the treatment of hyperlipidemia significantly reduced low-density lipoprotein...
Results from the DESCARTES...
06/18/2014
First Report Managed Care
06/18/2014
Kerri Fitzgerald
Diabetes medications are insulin-dependent, and the efficacy of these drugs diminishes when the function of pancreatic islet ß-cells declines during the progression of diabetes. Some diabetes drugs can cause weight gain in patients, which...
Diabetes medications are insulin-dependent, and the efficacy of these drugs diminishes when the function of pancreatic islet ß-cells declines during the progression of diabetes. Some diabetes drugs can cause weight gain in patients, which...
Diabetes medications are...
06/18/2014
First Report Managed Care
Managed Care Q&A
06/18/2014
First Report Managed Care conducted an interview with Norm Smith, one of our Editorial Advisory Board members, to discuss how the Patient Protection and Affordable Care Act (ACA) is impacting the managed markets, including costs, coverage,...
First Report Managed Care conducted an interview with Norm Smith, one of our Editorial Advisory Board members, to discuss how the Patient Protection and Affordable Care Act (ACA) is impacting the managed markets, including costs, coverage,...
First Report Managed Care...
06/18/2014
First Report Managed Care
06/18/2014
Eileen Koutnik-Fotopoulos
Inadequate health literacy is a pervasive problem with major implications for reduced health status and health disparities. Education is a fundamental strategy of stroke prevention and treatment, but the effect of health literacy on stroke...
Inadequate health literacy is a pervasive problem with major implications for reduced health status and health disparities. Education is a fundamental strategy of stroke prevention and treatment, but the effect of health literacy on stroke...
Inadequate health literacy is a...
06/18/2014
First Report Managed Care
06/18/2014
Tim Casey
The IMS Health Institute for Healthcare Informatics issued a report saying the US healthcare system could save in annual healthcare costs if medications were used responsibly.
The IMS Health Institute for Healthcare Informatics issued a report saying the US healthcare system could save in annual healthcare costs if medications were used responsibly.
The IMS Health Institute for...
06/18/2014
First Report Managed Care
Conference Insider
06/18/2014
Tim Casey
Orlando—By now, more than 4 years since the passage of the Patient Protection and Affordable Care Act (ACA), patients, providers, payers, and pharmaceutical companies have become accustomed to an evolving healthcare industry. Michael Lovdal,...
Orlando—By now, more than 4 years since the passage of the Patient Protection and Affordable Care Act (ACA), patients, providers, payers, and pharmaceutical companies have become accustomed to an evolving healthcare industry. Michael Lovdal,...
Orlando—By now, more than 4...
06/18/2014
First Report Managed Care