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July 2013 - FRMC

Department
07/22/2013
The FDA approved Sorilux™ (calcipotriene) Foam as a topical treatment for adults with plaque psoriasis of the scalp.
The FDA approved Sorilux™ (calcipotriene) Foam as a topical treatment for adults with plaque psoriasis of the scalp.
The FDA approved Sorilux™...
07/22/2013
First Report Managed Care
Department
07/22/2013
The FDA approved Jakafi® (ruxolitinib) in November 2011 to treat patients with myelofibrosis, a bone marrow disease. 
The FDA approved Jakafi® (ruxolitinib) in November 2011 to treat patients with myelofibrosis, a bone marrow disease. 
The FDA approved...
07/22/2013
First Report Managed Care
Department
07/22/2013
Tim Casey
Orlando—Treatment-naïve patients with hepatitis C who took 150 mg of simeprevir once daily in combination with peginterferon and ribavirin had a significantly better sustained virological response (SVR) rate compared with those taking...
Orlando—Treatment-naïve patients with hepatitis C who took 150 mg of simeprevir once daily in combination with peginterferon and ribavirin had a significantly better sustained virological response (SVR) rate compared with those taking...
Orlando—Treatment-naïve patients...
07/22/2013
First Report Managed Care
Conference Insider
07/22/2013
Tim Casey
Orlando—Clinicians have numerous options to treat patients with ulcerative colitis, a form of inflammatory bowel disease. The therapies include 5-amino-salacylic acid, thiopurine, and anti-tumor necrosis factor (TNF) agents such as...
Orlando—Clinicians have numerous options to treat patients with ulcerative colitis, a form of inflammatory bowel disease. The therapies include 5-amino-salacylic acid, thiopurine, and anti-tumor necrosis factor (TNF) agents such as...
Orlando—Clinicians have numerous...
07/22/2013
First Report Managed Care
Conference Insider
07/22/2013
Tim Casey
Orlando—An analysis of two phase 3 trials found that a higher percentage of patients who received linaclotide to treat abdominal and bowel symptoms had clinically meaningful improvement compared with a group receiving placebo. The clinically...
Orlando—An analysis of two phase 3 trials found that a higher percentage of patients who received linaclotide to treat abdominal and bowel symptoms had clinically meaningful improvement compared with a group receiving placebo. The clinically...
Orlando—An analysis of two phase...
07/22/2013
First Report Managed Care
Conference Insider
07/22/2013
Tim Casey
Orlando—Patients with venous thromboembolism (VTE) who took extended duration thromboprophylaxis had an incremental cost-effectiveness ratio of $8123 per quality-adjusted life year (QALY), according to a cost-effectiveness decision tree...
Orlando—Patients with venous thromboembolism (VTE) who took extended duration thromboprophylaxis had an incremental cost-effectiveness ratio of $8123 per quality-adjusted life year (QALY), according to a cost-effectiveness decision tree...
Orlando—Patients with venous...
07/22/2013
First Report Managed Care
07/22/2013
Tim Casey
Patients with irritable bowel syndrome whose symptoms improved after 4 weeks of treatment with linaclotide were highly likely to continue feeling better at week 12.
Patients with irritable bowel syndrome whose symptoms improved after 4 weeks of treatment with linaclotide were highly likely to continue feeling better at week 12.
Patients with irritable bowel...
07/22/2013
First Report Managed Care
Conference Insider
07/22/2013
Tim Casey
Orlando—After controlling for patient and operative factors, the authors in a study of patients undergoing major gastrointestinal surgeries found numerous factors were associated with an increased risk of 30-day unplanned readmissions.
Orlando—After controlling for patient and operative factors, the authors in a study of patients undergoing major gastrointestinal surgeries found numerous factors were associated with an increased risk of 30-day unplanned readmissions.
Orlando—After controlling for...
07/22/2013
First Report Managed Care
Conference Insider
07/22/2013
Tim Casey
Orlando—As screening rates for colorectal cancer have increased in recent years, the incidence and death rates due to the disease have declined. Still, approximately 22 million people in the United States have never been screened, and the...
Orlando—As screening rates for colorectal cancer have increased in recent years, the incidence and death rates due to the disease have declined. Still, approximately 22 million people in the United States have never been screened, and the...
Orlando—As screening rates for...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
Chicago—Among the estimated 26,870 women who were diagnosed with breast cancer in 2012, 20% had tumors that overexpress the human epidermal growth factor 2 (HER2) gene, a marker of severity of disease that can influence therapy selection. All...
Chicago—Among the estimated 26,870 women who were diagnosed with breast cancer in 2012, 20% had tumors that overexpress the human epidermal growth factor 2 (HER2) gene, a marker of severity of disease that can influence therapy selection. All...
Chicago—Among the estimated...
07/22/2013
First Report Managed Care
News
07/22/2013
Tim Casey
Chicago—An analysis of a phase 3, randomized, multicenter, open-label study found that patients with pretreated relapsed and refractory multiple myeloma had an improvement in health-related quality of life if they received pomalidomide plus...
Chicago—An analysis of a phase 3, randomized, multicenter, open-label study found that patients with pretreated relapsed and refractory multiple myeloma had an improvement in health-related quality of life if they received pomalidomide plus...
Chicago—An analysis of a phase...
07/22/2013
First Report Managed Care
07/22/2013
Tim Casey
Patients with cancer who had breakthrough pain were statistically significantly more likely to have daily functioning problems compared with cancer patients who are pain-free, according to a database analysis of commercially-insured health...
Patients with cancer who had breakthrough pain were statistically significantly more likely to have daily functioning problems compared with cancer patients who are pain-free, according to a database analysis of commercially-insured health...
Patients with cancer who had...
07/22/2013
First Report Managed Care
07/22/2013
Tim Casey
The initial study in humans of the investigational agent BMN 673 found that the oral drug has substantial anti-tumor activity in deleterious germline BRCA ovarian and breast cancer, according to a phase 1/2 trial.
The initial study in humans of the investigational agent BMN 673 found that the oral drug has substantial anti-tumor activity in deleterious germline BRCA ovarian and breast cancer, according to a phase 1/2 trial.
The initial study in humans of...
07/22/2013
First Report Managed Care
07/22/2013
Tim Casey
Patients with recurrent and metastatic cervical cancer who received bevacizumab with their chemotherapy regimens had statistically significant improvement in overall survival compared with those taking chemotherapy alone. 
Patients with recurrent and metastatic cervical cancer who received bevacizumab with their chemotherapy regimens had statistically significant improvement in overall survival compared with those taking chemotherapy alone. 
Patients with recurrent and...
07/22/2013
First Report Managed Care
07/22/2013
Tim Casey
Chicago—After a year of treatment, 68.9% of patients with metastatic melanoma who took ipilimumab plus sargramostin were alive compared with 52.9% of patients who received ipilimumab alone, according to a multicenter, randomized, phase 2...
Chicago—After a year of treatment, 68.9% of patients with metastatic melanoma who took ipilimumab plus sargramostin were alive compared with 52.9% of patients who received ipilimumab alone, according to a multicenter, randomized, phase 2...
Chicago—After a year of...
07/22/2013
First Report Managed Care
Conference Insider
07/22/2013
Tim Casey
Chicago—An international, multicenter, double-blind, randomized, phase 3 trial found that patients with radioactive iodine-refractory differentiated thyroid cancer who took sorafenib had a significant improvement in progression-free survival...
Chicago—An international, multicenter, double-blind, randomized, phase 3 trial found that patients with radioactive iodine-refractory differentiated thyroid cancer who took sorafenib had a significant improvement in progression-free survival...
Chicago—An international,...
07/22/2013
First Report Managed Care
07/22/2013
Tim Casey
Patients with advanced ovarian cancer who took pazopanib daily after initial treatment with surgery and chemotherapy had significantly longer progression-free survival compared with those who received placebo. 
Patients with advanced ovarian cancer who took pazopanib daily after initial treatment with surgery and chemotherapy had significantly longer progression-free survival compared with those who received placebo. 
Patients with advanced ovarian...
07/22/2013
First Report Managed Care
07/22/2013
Tim Casey
  Chicago—Patients with hormone-naïve prostate cancer who took 160 mg of enzalutamide daily for 24 weeks had a median decrease in prostate-specific antigen (PSA) of 99.6%, according to a phase 2, open-label, single-arm study. In addition,...
  Chicago—Patients with hormone-naïve prostate cancer who took 160 mg of enzalutamide daily for 24 weeks had a median decrease in prostate-specific antigen (PSA) of 99.6%, according to a phase 2, open-label, single-arm study. In addition,...
  Chicago—Patients with...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
There is a growing model of inpatient care that includes the use of hospitalists, which may be one of the factors exacerbating the already poor level of communication between inpatient and outpatient healthcare providers. The discontinuity of...
There is a growing model of inpatient care that includes the use of hospitalists, which may be one of the factors exacerbating the already poor level of communication between inpatient and outpatient healthcare providers. The discontinuity of...
There is a growing model of...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
A common costly component to overall healthcare costs is hospital readmission. The 30-day readmission rate in the United States is 18% according to recent studies, and the cost of readmissions among Medicare beneficiaries is an estimated $17...
A common costly component to overall healthcare costs is hospital readmission. The 30-day readmission rate in the United States is 18% according to recent studies, and the cost of readmissions among Medicare beneficiaries is an estimated $17...
A common costly component to...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
Exacerbations of chronic obstructive pulmonary disease (COPD) are risk factors for disease progression. Patients with COPD who experience frequent acute exacerbations are at increased risk for death. In a study cohort in Switzerland, 23% to...
Exacerbations of chronic obstructive pulmonary disease (COPD) are risk factors for disease progression. Patients with COPD who experience frequent acute exacerbations are at increased risk for death. In a study cohort in Switzerland, 23% to...
Exacerbations of chronic...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
A large and growing population of Americans are being diagnosed with dementia, a chronic disease of aging characterized by progressive cognitive decline that interferes with independent functioning. In January 2011, President Barack Obama...
A large and growing population of Americans are being diagnosed with dementia, a chronic disease of aging characterized by progressive cognitive decline that interferes with independent functioning. In January 2011, President Barack Obama...
A large and growing population...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
In the past 10 years, according to researchers, the concept of physicians informing and involving patients in medical decisions has begun to take hold, at least in policy circles. The American Medical Association has endorsed the concept of...
In the past 10 years, according to researchers, the concept of physicians informing and involving patients in medical decisions has begun to take hold, at least in policy circles. The American Medical Association has endorsed the concept of...
In the past 10 years, according...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
It is estimated that lung cancer, the largest single cause of cancer death in the world, will account for >100,000 deaths in the United States in 2013. The majority of patients with lung cancer have been smokers and half of the 94 million...
It is estimated that lung cancer, the largest single cause of cancer death in the world, will account for >100,000 deaths in the United States in 2013. The majority of patients with lung cancer have been smokers and half of the 94 million...
It is estimated that lung...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
Approximately 400,000 Americans undergo long-term dialysis and patients with end-stage renal disease in the United States have a 20% to 25% 1-year mortality rate, which is comparable to many types of cancer. Being given an accurate estimate...
Approximately 400,000 Americans undergo long-term dialysis and patients with end-stage renal disease in the United States have a 20% to 25% 1-year mortality rate, which is comparable to many types of cancer. Being given an accurate estimate...
Approximately 400,000 Americans...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
Since 2006, Medicare Part D has had a policy that excludes benzodiazepines from mandatory drug coverage. The restriction had increased the use of nonbenzodiazepine sleep medications (zolpidem tartrate) to treat insomnia in nursing homes in...
Since 2006, Medicare Part D has had a policy that excludes benzodiazepines from mandatory drug coverage. The restriction had increased the use of nonbenzodiazepine sleep medications (zolpidem tartrate) to treat insomnia in nursing homes in...
Since 2006, Medicare Part D has...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
According to the Centers for Disease Control and Prevention (CDC), there are an estimated 3.2 million people in the United States living with hepatitis C virus (HCV) infection and new infections continue to occur. Once infected with HCV,...
According to the Centers for Disease Control and Prevention (CDC), there are an estimated 3.2 million people in the United States living with hepatitis C virus (HCV) infection and new infections continue to occur. Once infected with HCV,...
According to the Centers for...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
Diabetes mellitus has been diagnosed in an estimated 18.8 million adults in the United States. Patients with diabetes are at increased risk for disabling and life-threatening complications from microvascular diseases (affecting the kidneys,...
Diabetes mellitus has been diagnosed in an estimated 18.8 million adults in the United States. Patients with diabetes are at increased risk for disabling and life-threatening complications from microvascular diseases (affecting the kidneys,...
Diabetes mellitus has been...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
Decreasing preventable hospital-acquired conditions by 40% by the end of 2013 is a goal established by the US Department of Health & Human Services. The initiative to reduce those conditions included a focus on healthcare-associated...
Decreasing preventable hospital-acquired conditions by 40% by the end of 2013 is a goal established by the US Department of Health & Human Services. The initiative to reduce those conditions included a focus on healthcare-associated...
Decreasing preventable...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
Researchers recently conducted a study to examine the impact of treatment delay time as well as race/ethnicity, socioeconomic status, insurance status, cancer stage, and age on survival from breast cancer among adolescent and young...
Researchers recently conducted a study to examine the impact of treatment delay time as well as race/ethnicity, socioeconomic status, insurance status, cancer stage, and age on survival from breast cancer among adolescent and young...
Researchers recently conducted a...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
Worldwide, cervical cancer is the second most common cause of cancer morbidity and mortality in women. Human papillomavirus (HPV) is a necessary cause for the development of cervical cancer; HPV genotypes 16 and 18 account for approximately...
Worldwide, cervical cancer is the second most common cause of cancer morbidity and mortality in women. Human papillomavirus (HPV) is a necessary cause for the development of cervical cancer; HPV genotypes 16 and 18 account for approximately...
Worldwide, cervical cancer is...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
According to researchers, “Hypoglycemia is a serious sequela of diabetes treatment not tracked by formal health surveillance. Associated harms span vehicle crashes and injuries, missed work, debilitating worry, medical complications, and...
According to researchers, “Hypoglycemia is a serious sequela of diabetes treatment not tracked by formal health surveillance. Associated harms span vehicle crashes and injuries, missed work, debilitating worry, medical complications, and...
According to researchers,...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
The most common noncardiac complication of percutaneous coronary intervention (PCI) is bleeding. Bleeding following PCI is associated with short- and long-term death, nonfatal myocardial infarction, stroke, blood transfusion, prolonged...
The most common noncardiac complication of percutaneous coronary intervention (PCI) is bleeding. Bleeding following PCI is associated with short- and long-term death, nonfatal myocardial infarction, stroke, blood transfusion, prolonged...
The most common noncardiac...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
According to researchers, individuals infected with HIV often experience hepatitis C virus (HCV) coinfection. Among patients treated with effective HIV antiretroviral therapy (ART), the presence of HCV infection has been associated with an...
According to researchers, individuals infected with HIV often experience hepatitis C virus (HCV) coinfection. Among patients treated with effective HIV antiretroviral therapy (ART), the presence of HCV infection has been associated with an...
According to researchers,...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Jill Sederstorm
A study investigating the cost effectiveness of diabetes mellitus screening strategies for children found that the cost per case was extremely high for all screening options; however, researchers noted that screening could be more cost...
A study investigating the cost effectiveness of diabetes mellitus screening strategies for children found that the cost per case was extremely high for all screening options; however, researchers noted that screening could be more cost...
A study investigating the cost...
07/22/2013
First Report Managed Care
07/22/2013
Kevin L. Carter
Enoxaparin sodium, a heparin with a low molecular weight, allows for simplified dosing without the need for vigilant monitoring through laboratory tests.
Enoxaparin sodium, a heparin with a low molecular weight, allows for simplified dosing without the need for vigilant monitoring through laboratory tests.
Enoxaparin sodium, a heparin...
07/22/2013
First Report Managed Care
07/22/2013
Tori Socha
The incidence rate of cancer in patients with mental illness is similar to that in patients without mental illness; however, overall mortality in cancer patients with mental illness is higher than in the general population. The rate of...
The incidence rate of cancer in patients with mental illness is similar to that in patients without mental illness; however, overall mortality in cancer patients with mental illness is higher than in the general population. The rate of...
The incidence rate of cancer in...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
Standard treatment for tight blood glucose control in patients with type 1 diabetes is intensive insulin therapy designed to prevent long-term complications. The use of insulin pumps, glucose sensors, or a combination of the 2 devices has...
Standard treatment for tight blood glucose control in patients with type 1 diabetes is intensive insulin therapy designed to prevent long-term complications. The use of insulin pumps, glucose sensors, or a combination of the 2 devices has...
Standard treatment for tight...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tori Socha
There is a shortage of primary care physicians in the United States, a situation made more critical in the face of an aging population and an increase in the incidence and prevalence of chronic illnesses. When the provisions of the Patient...
There is a shortage of primary care physicians in the United States, a situation made more critical in the face of an aging population and an increase in the incidence and prevalence of chronic illnesses. When the provisions of the Patient...
There is a shortage of primary...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tim Casey
As drugs become close to losing patent protection, brand manufacturers typically want to extend the exclusivity of their drugs for as long as possible. They spend billions of dollars to develop and market the products, which can generate...
As drugs become close to losing patent protection, brand manufacturers typically want to extend the exclusivity of their drugs for as long as possible. They spend billions of dollars to develop and market the products, which can generate...
As drugs become close to losing...
07/22/2013
First Report Managed Care
News Connection
07/22/2013
Tim Casey
Since the mid-1990s, Jonathan Tobin, PhD, and his colleagues have conducted research studies focused on increasing cancer screening among minority women. Three times, they received funding from the National Cancer Institute to assess patient...
Since the mid-1990s, Jonathan Tobin, PhD, and his colleagues have conducted research studies focused on increasing cancer screening among minority women. Three times, they received funding from the National Cancer Institute to assess patient...
Since the mid-1990s, Jonathan...
07/22/2013
First Report Managed Care