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December 2012 - FRMC

12/17/2012
Kevin L. Carter
Alzheimer disease (AD) is the most common cause of dementia and currently affects about 5 million Americans. By 2050, this number is expected to increase to 13 million.
Alzheimer disease (AD) is the most common cause of dementia and currently affects about 5 million Americans. By 2050, this number is expected to increase to 13 million.
Alzheimer disease (AD) is the...
12/17/2012
First Report Managed Care
12/17/2012
Kevin L. Carter
Two important human lentiviruses have been described: (1) pandemic HIV type 1 (HIV-1), and (2) HIV type 2 (HIV-2), which is mainly confined to West Africa. Both viruses have similar transmission routes, cellular targets, and AIDS-defining...
Two important human lentiviruses have been described: (1) pandemic HIV type 1 (HIV-1), and (2) HIV type 2 (HIV-2), which is mainly confined to West Africa. Both viruses have similar transmission routes, cellular targets, and AIDS-defining...
Two important human lentiviruses...
12/17/2012
First Report Managed Care
12/17/2012
Tim Casey
Boston—Patients with hepatitis C had similar sustained virologic response rates after 12 weeks whether they took 1125 mg of telaprevir twice daily or 750 mg of telaprevir every 8 hours, according to a randomized, open-label, multicenter,...
Boston—Patients with hepatitis C had similar sustained virologic response rates after 12 weeks whether they took 1125 mg of telaprevir twice daily or 750 mg of telaprevir every 8 hours, according to a randomized, open-label, multicenter,...
Boston—Patients with hepatitis C...
12/17/2012
First Report Managed Care
12/17/2012
Tim Casey
Boston—An analysis of clinical trials found that co-infected patients had a reduction in boceprevir exposure compared with mono-infected patients with hepatitis C. The authors noted the difference likely occurred because of an interaction...
Boston—An analysis of clinical trials found that co-infected patients had a reduction in boceprevir exposure compared with mono-infected patients with hepatitis C. The authors noted the difference likely occurred because of an interaction...
Boston—An analysis of clinical...
12/17/2012
First Report Managed Care
Conference Insider
12/17/2012
Eileen Koutnik-Fotopoulos
San Diego—Insomnia is prevalent in the general population and quite common among people with mental health disorders. Approximately 50 to 70 million Americans suffer from chronic sleep disorders that adversely affect daily functioning,...
San Diego—Insomnia is prevalent in the general population and quite common among people with mental health disorders. Approximately 50 to 70 million Americans suffer from chronic sleep disorders that adversely affect daily functioning,...
San Diego—Insomnia is prevalent...
12/17/2012
First Report Managed Care
12/17/2012
Eileen Koutnik-Fotopoulos
San Diego—A retrospective cohort analysis of medical and pharmacy claims data from 24 state Medicaid plans found that schizophrenia patients newly treated with the atypical antipsychotic (AA) aripiprazole had lower hospitalization rates and...
San Diego—A retrospective cohort analysis of medical and pharmacy claims data from 24 state Medicaid plans found that schizophrenia patients newly treated with the atypical antipsychotic (AA) aripiprazole had lower hospitalization rates and...
San Diego—A retrospective cohort...
12/17/2012
First Report Managed Care
12/17/2012
Eileen Koutnik-Fotopoulos
San Diego—Data from 2 pivotal trials of 891 patients demonstrated that vilazodone was significantly superior to placebo on all depression rating scales tested, according to results presented during a poster session at the Psych Congress. The...
San Diego—Data from 2 pivotal trials of 891 patients demonstrated that vilazodone was significantly superior to placebo on all depression rating scales tested, according to results presented during a poster session at the Psych Congress. The...
San Diego—Data from 2 pivotal...
12/17/2012
First Report Managed Care
Conference Insider
12/17/2012
Eileen Koutnik-Fotopoulos
San Diego—Combination therapy has been used informally in mental health, but new evidence is emerging that combination therapy is safe and effective for difficult and treatment-resistant cases of attention-deficit hyperactivity disorder...
San Diego—Combination therapy has been used informally in mental health, but new evidence is emerging that combination therapy is safe and effective for difficult and treatment-resistant cases of attention-deficit hyperactivity disorder...
San Diego—Combination therapy...
12/17/2012
First Report Managed Care
12/17/2012
Tim Casey
Las Vegas—Research presented during a session at the Fall Managed Care Forum showed that employers, employees, and health plans can benefit from implementing wellness programs, managing chronic conditions such as diabetes, and having on-site...
Las Vegas—Research presented during a session at the Fall Managed Care Forum showed that employers, employees, and health plans can benefit from implementing wellness programs, managing chronic conditions such as diabetes, and having on-site...
Las Vegas—Research presented...
12/17/2012
First Report Managed Care
12/17/2012
Tim Casey
Las Vegas—Soon after patients are diagnosed with rheumatoid arthritis (RA), they experience symptoms, and, within 2 years, they have a moderate loss of function that can contribute to health problems, lost work time, and other issues. To...
Las Vegas—Soon after patients are diagnosed with rheumatoid arthritis (RA), they experience symptoms, and, within 2 years, they have a moderate loss of function that can contribute to health problems, lost work time, and other issues. To...
Las Vegas—Soon after patients...
12/17/2012
First Report Managed Care
12/17/2012
Tim Casey
Las Vegas—Regardless of the rising costs of oncology drugs, health insurers, the federal government, and other payers are increasingly likely to cover oncology medications, according to a recent survey. The 2012 Eisai Oncology Digest asked...
Las Vegas—Regardless of the rising costs of oncology drugs, health insurers, the federal government, and other payers are increasingly likely to cover oncology medications, according to a recent survey. The 2012 Eisai Oncology Digest asked...
Las Vegas—Regardless of the...
12/17/2012
First Report Managed Care
12/17/2012
Tim Casey
Las Vegas—Major depression disorder (MDD) is the most common psychiatric disorder in the United States, but few Americans with MDD receive optimum treatment, according to Ken Hopper, MD, executive consultant at BHM Healthcare Solutions, a...
Las Vegas—Major depression disorder (MDD) is the most common psychiatric disorder in the United States, but few Americans with MDD receive optimum treatment, according to Ken Hopper, MD, executive consultant at BHM Healthcare Solutions, a...
Las Vegas—Major depression...
12/17/2012
First Report Managed Care
12/17/2012
Tim Casey
Las Vegas—Treating patients with chronic pain can cause difficulties since there are both physiological components and psychological issues, which can lead to irritability or depression and make the condition even worse.
Las Vegas—Treating patients with chronic pain can cause difficulties since there are both physiological components and psychological issues, which can lead to irritability or depression and make the condition even worse.
Las Vegas—Treating patients with...
12/17/2012
First Report Managed Care
12/17/2012
Tori Socha
The Patient Protection and Affordable Care Act (ACA) includes provisions that require private health insurance companies to cover recommended preventive services with no patient cost-sharing, including copayments and deductibles. The...
The Patient Protection and Affordable Care Act (ACA) includes provisions that require private health insurance companies to cover recommended preventive services with no patient cost-sharing, including copayments and deductibles. The...
The Patient Protection and...
12/17/2012
First Report Managed Care
12/17/2012
Tori Socha
The prevalence of asthma has increased across all age groups over the past 10 years. Asthma is a chronic inflammatory disorder of the airways and adverse health outcomes can result when it is poorly controlled. Guidelines for the management...
The prevalence of asthma has increased across all age groups over the past 10 years. Asthma is a chronic inflammatory disorder of the airways and adverse health outcomes can result when it is poorly controlled. Guidelines for the management...
The prevalence of asthma has...
12/17/2012
First Report Managed Care
12/17/2012
Tori Socha
In the years between 1998 and 2009, the number of adults reporting treatment for asthma nearly doubled from 5.5 million (2.7% of US adults ≥18 years of age) in 1998 to 10.3 million (4.5%). Asthma is a chronic respiratory disease that causes...
In the years between 1998 and 2009, the number of adults reporting treatment for asthma nearly doubled from 5.5 million (2.7% of US adults ≥18 years of age) in 1998 to 10.3 million (4.5%). Asthma is a chronic respiratory disease that causes...
In the years between 1998 and...
12/17/2012
First Report Managed Care
12/17/2012
Tori Socha
Previous studies have demonstrated associations between obesity and type 2 diabetes, and between changes in body weight and incident type 2 diabetes. There is also an association between the increase worldwide in obesity and the increased...
Previous studies have demonstrated associations between obesity and type 2 diabetes, and between changes in body weight and incident type 2 diabetes. There is also an association between the increase worldwide in obesity and the increased...
Previous studies have...
12/17/2012
First Report Managed Care
12/17/2012
Eileen Koutnik-Fotopoulos
An analysis of 6 of the most novel risk factors for improvement in cardiovascular risk assessment found 4 markers that were independent predictors of incident coronary heart disease (CHD)/cardiovascular disease (CVD) in intermediate-risk...
An analysis of 6 of the most novel risk factors for improvement in cardiovascular risk assessment found 4 markers that were independent predictors of incident coronary heart disease (CHD)/cardiovascular disease (CVD) in intermediate-risk...
An analysis of 6 of the most...
12/17/2012
First Report Managed Care
12/17/2012
Alice Brindle
Benefits of screening for prostate cancer include reduction in disease-related mortality, increase in the number of life-years gained, and a reduction in the rate of advanced disease. However, prostate-specific antigen (PSA) screening is...
Benefits of screening for prostate cancer include reduction in disease-related mortality, increase in the number of life-years gained, and a reduction in the rate of advanced disease. However, prostate-specific antigen (PSA) screening is...
Benefits of screening for...
12/17/2012
First Report Managed Care
12/17/2012
Mary Beth Nierengarten
Results of a phase 3, double-blind, placebo-controlled study [N Engl J Med. 2012;367(6):495-507] show that tofacitinib monotherapy is associated with a reduction in signs and symptoms of rheumatoid arthritis (RA) and improvement in physical...
Results of a phase 3, double-blind, placebo-controlled study [N Engl J Med. 2012;367(6):495-507] show that tofacitinib monotherapy is associated with a reduction in signs and symptoms of rheumatoid arthritis (RA) and improvement in physical...
Results of a phase 3,...
12/17/2012
First Report Managed Care
12/17/2012
Mary Beth Nierengarten
Results of a randomized, prospective, open-label, multicenter trial [N Engl J Med. 2012; DOI:10.1056/NEJMoa1208410] showed no significant reduction in 30-day mortality in patients with cardiogenic shock complicating acute myocardial...
Results of a randomized, prospective, open-label, multicenter trial [N Engl J Med. 2012; DOI:10.1056/NEJMoa1208410] showed no significant reduction in 30-day mortality in patients with cardiogenic shock complicating acute myocardial...
Results of a randomized,...
12/17/2012
First Report Managed Care
12/17/2012
Kevin L. Carter
The long-term prognosis for older patients with mantle-cell lymphoma is poor. Only a minority of patients have a complete remission, and relapse or progression usually occurs within 2 to 3 years, resulting in an overall survival of <5...
The long-term prognosis for older patients with mantle-cell lymphoma is poor. Only a minority of patients have a complete remission, and relapse or progression usually occurs within 2 to 3 years, resulting in an overall survival of <5...
The long-term prognosis for...
12/17/2012
First Report Managed Care
12/17/2012
Mary Mihalovic
Patients with active ulcerative colitis and treated with the selective oral Janus kinase inhibitor tofacitinib were more likely to show clinical response and remission.
Patients with active ulcerative colitis and treated with the selective oral Janus kinase inhibitor tofacitinib were more likely to show clinical response and remission.
Patients with active ulcerative...
12/17/2012
First Report Managed Care
12/17/2012
Tori Socha
The intensity of pancreatitis can range from a mild, self-limiting episode to a severe or even fatal event. There have been case reports and studies suggesting that pancreatitis may be caused by statin use. According to researchers, few of...
The intensity of pancreatitis can range from a mild, self-limiting episode to a severe or even fatal event. There have been case reports and studies suggesting that pancreatitis may be caused by statin use. According to researchers, few of...
The intensity of pancreatitis...
12/17/2012
First Report Managed Care
News
12/17/2012
Tori Socha
Multiple sclerosis (MS) is a multi-faceted autoimmune demyelinating disorder affecting >400,000 individuals in the United States. Prevention of relapses in patients with MS is a primary goal of MS therapy. Confirmation of a relapse in...
Multiple sclerosis (MS) is a multi-faceted autoimmune demyelinating disorder affecting >400,000 individuals in the United States. Prevention of relapses in patients with MS is a primary goal of MS therapy. Confirmation of a relapse in...
Multiple sclerosis (MS) is a...
12/17/2012
First Report Managed Care
News
12/17/2012
Tori Socha
Multiple sclerosis (MS), a chronic condition that usually affects people in the prime of their lives, is characterized by clinical progression over time manifested by the accumulation of disability. The most widely prescribed...
Multiple sclerosis (MS), a chronic condition that usually affects people in the prime of their lives, is characterized by clinical progression over time manifested by the accumulation of disability. The most widely prescribed...
Multiple sclerosis (MS), a...
12/17/2012
First Report Managed Care
News
12/17/2012
Tori Socha
The most common disabling neurologic disease among adults 18 to 60 years of age is multiple sclerosis (MS). Disease-modifying therapies (DMTs) are the gold standard of disease management for MS, with the goal of preventing or delaying...
The most common disabling neurologic disease among adults 18 to 60 years of age is multiple sclerosis (MS). Disease-modifying therapies (DMTs) are the gold standard of disease management for MS, with the goal of preventing or delaying...
The most common disabling...
12/17/2012
First Report Managed Care
News
12/17/2012
Tori Socha
Parenteral agents (interferon beta and glatiramer acetate) are common treatments for multiple sclerosis (MS), a chronic demyelinating and neurodegenerative disease of the central nervous system. According to researchers, oxidative stress and...
Parenteral agents (interferon beta and glatiramer acetate) are common treatments for multiple sclerosis (MS), a chronic demyelinating and neurodegenerative disease of the central nervous system. According to researchers, oxidative stress and...
Parenteral agents (interferon...
12/17/2012
First Report Managed Care
12/17/2012
Tori Socha
Ensuring that all individuals in the United States who are living with HIV have access to quality healthcare has been a challenge since the onset of the epidemic. The Patient Protection and Affordable Care Act (ACA) is designed to expand...
Ensuring that all individuals in the United States who are living with HIV have access to quality healthcare has been a challenge since the onset of the epidemic. The Patient Protection and Affordable Care Act (ACA) is designed to expand...
Ensuring that all individuals in...
12/17/2012
First Report Managed Care
Conference Insider
12/17/2012
Tim Casey
Las Vegas—It is no secret healthcare providers are facing challenges. Hospitals and physicians have struggled with reimbursement and profitability. They are also concerned with selected provisions of the Patient Protection and Affordable Care...
Las Vegas—It is no secret healthcare providers are facing challenges. Hospitals and physicians have struggled with reimbursement and profitability. They are also concerned with selected provisions of the Patient Protection and Affordable Care...
Las Vegas—It is no secret...
12/17/2012
First Report Managed Care
Conference Insider
12/17/2012
Tim Casey
Las Vegas—For the past 15 years, federal government legislation has helped transform the healthcare industry. In 1997, the Balanced Budget Act established the Medicare sustainable growth rate, which has led to a $300 billion underfunded...
Las Vegas—For the past 15 years, federal government legislation has helped transform the healthcare industry. In 1997, the Balanced Budget Act established the Medicare sustainable growth rate, which has led to a $300 billion underfunded...
Las Vegas—For the past 15 years,...
12/17/2012
First Report Managed Care