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August 2013 - FRMC

08/15/2013
The FDA approved tazarotene foam for acne vulgaris based on the results of two, phase 3 studies conducted in the US and Canada. 
The FDA approved tazarotene foam for acne vulgaris based on the results of two, phase 3 studies conducted in the US and Canada. 
The FDA approved tazarotene foam...
08/15/2013
First Report Managed Care
08/15/2013
Tori Socha
Chicago—Of patients with chronic myeloid leukemia (CML) who are treated with tyrosine-kinase inhibitors (TKIs), 20% to 30% develop resistance to the drugs; others are intolerant.
Chicago—Of patients with chronic myeloid leukemia (CML) who are treated with tyrosine-kinase inhibitors (TKIs), 20% to 30% develop resistance to the drugs; others are intolerant.
Chicago—Of patients with chronic...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—After 2 years of treatment, 43% of patients with advanced melanoma who received nivolumab were alive, according to a phase 1 study. The 1-year overall survival rate was 62%, and median overall survival was 16.8 months. All patients...
Chicago—After 2 years of treatment, 43% of patients with advanced melanoma who received nivolumab were alive, according to a phase 1 study. The 1-year overall survival rate was 62%, and median overall survival was 16.8 months. All patients...
Chicago—After 2 years of...
08/15/2013
First Report Managed Care
08/15/2013
Tori Socha
Chicago—A broad perspective of disease burden and impact of treatment may be gained utilizing patient-reported outcomes (PROs) such as health-related quality of life (HRQoL). For patients with multiple myeloma (MM) and other hematologic...
Chicago—A broad perspective of disease burden and impact of treatment may be gained utilizing patient-reported outcomes (PROs) such as health-related quality of life (HRQoL). For patients with multiple myeloma (MM) and other hematologic...
Chicago—A broad perspective of...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—At a minimum of 15 months follow-up, patients with unresectable, metastatic BRAF wild-type melanoma who received 24 mg of lenvatinib once daily had a median progression-free survival of 3.7 months and a median overall survival of 9.5...
Chicago—At a minimum of 15 months follow-up, patients with unresectable, metastatic BRAF wild-type melanoma who received 24 mg of lenvatinib once daily had a median progression-free survival of 3.7 months and a median overall survival of 9.5...
Chicago—At a minimum of 15...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—According to a survey, most oncologists and hematologists have faced drug shortages in recent years and have had to deny, delay, or modify treatment regimens for cancer patients. Although the scarcity of these drugs has received...
Chicago—According to a survey, most oncologists and hematologists have faced drug shortages in recent years and have had to deny, delay, or modify treatment regimens for cancer patients. Although the scarcity of these drugs has received...
Chicago—According to a survey,...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Patients with moderate-to-severe chronic low back pain who received 12 weeks of treatment with the Butrans® (buprenorphine) transdermal system had significant improvements in several activities of daily living compared with a placebo group.
Patients with moderate-to-severe chronic low back pain who received 12 weeks of treatment with the Butrans® (buprenorphine) transdermal system had significant improvements in several activities of daily living compared with a placebo group.
Patients with moderate-to-severe...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
An analysis of a claims database found that 61% of patients with diabetic peripheral neuropathy had not received treatment for the disease.Although if patients took medications, they typically used opioids to manage the condition.
An analysis of a claims database found that 61% of patients with diabetic peripheral neuropathy had not received treatment for the disease.Although if patients took medications, they typically used opioids to manage the condition.
An analysis of a claims database...
08/15/2013
First Report Managed Care
Conference Insider
08/15/2013
Tim Casey
Fort Lauderdale—In the United States, approximately 100 million adults have chronic pain, which is associated with $275 billion in healthcare costs and $300 billion in lost worker productivity each year. The combined costs are larger than...
Fort Lauderdale—In the United States, approximately 100 million adults have chronic pain, which is associated with $275 billion in healthcare costs and $300 billion in lost worker productivity each year. The combined costs are larger than...
Fort Lauderdale—In the United...
08/15/2013
First Report Managed Care
08/15/2013
Tori Socha
There are limited options available for the treatment of irritable bowel syndrome with constipation, but linaclotide has recently been approved.
There are limited options available for the treatment of irritable bowel syndrome with constipation, but linaclotide has recently been approved.
There are limited options...
08/15/2013
First Report Managed Care
08/15/2013
Tori Socha
Irritable bowel syndrome (chronic functional gastrointestinal disorder) causes low quality of life and psychosocial wellbeing, and decreased sexual desire.
Irritable bowel syndrome (chronic functional gastrointestinal disorder) causes low quality of life and psychosocial wellbeing, and decreased sexual desire.
Irritable bowel...
08/15/2013
First Report Managed Care
08/15/2013
Tori Socha
  Orlando—Characterizing the therapeutic benefit of novel agents for irritable bowel syndrome relies heavily on patient-reported outcomes (PROs) assessing multiple gastrointestinal symptoms. Common approaches that sum or average responses...
  Orlando—Characterizing the therapeutic benefit of novel agents for irritable bowel syndrome relies heavily on patient-reported outcomes (PROs) assessing multiple gastrointestinal symptoms. Common approaches that sum or average responses...
  Orlando—Characterizing the...
08/15/2013
First Report Managed Care
Conference Insider
08/15/2013
Tori Socha
Researchers conducted a study to identify trends in IBS-related physician visits, evaluation, and management in the United States over the past 2 decades.
Researchers conducted a study to identify trends in IBS-related physician visits, evaluation, and management in the United States over the past 2 decades.
Researchers conducted a study to...
08/15/2013
First Report Managed Care
08/15/2013
Tori Socha
Previous studies have demonstrated that an effective patient-physician relationship can improve clinical outcomes in patients with irritable bowel syndrome (IBS).
Previous studies have demonstrated that an effective patient-physician relationship can improve clinical outcomes in patients with irritable bowel syndrome (IBS).
Previous studies have...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—Obese or overweight adults with dysglycemia who received phentermine and topiramate extended-release pills had a mean weight loss of 7.7% to 11.6% after 56 weeks of treatment, according to a post hoc analysis of a randomized,...
Chicago—Obese or overweight adults with dysglycemia who received phentermine and topiramate extended-release pills had a mean weight loss of 7.7% to 11.6% after 56 weeks of treatment, according to a post hoc analysis of a randomized,...
Chicago—Obese or overweight...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—Patients with type 2 diabetes who took linagliptin were not at higher risk of having cardiovascular events compared with patients who took other drugs, according to an analysis of 19 multicenter, randomized, double-blind, parallel...
Chicago—Patients with type 2 diabetes who took linagliptin were not at higher risk of having cardiovascular events compared with patients who took other drugs, according to an analysis of 19 multicenter, randomized, double-blind, parallel...
Chicago—Patients with type 2...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—Compared with a group receiving placebo, patients with type 2 diabetes who took 100 mg or 300 mg of canagliflozin had improvements in glycemic control and reductions in body weight, according to a pooled data analysis of 4 randomized,...
Chicago—Compared with a group receiving placebo, patients with type 2 diabetes who took 100 mg or 300 mg of canagliflozin had improvements in glycemic control and reductions in body weight, according to a pooled data analysis of 4 randomized,...
Chicago—Compared with a group...
08/15/2013
First Report Managed Care
Conference Insider
08/15/2013
Tim Casey
Chicago—An analysis of a large lifestyle change program in patients with type 2 diabetes found that diet and exercise modification can help patients, although <10% of participants were actively involved in the program. Sandra L. Jackson,...
Chicago—An analysis of a large lifestyle change program in patients with type 2 diabetes found that diet and exercise modification can help patients, although <10% of participants were actively involved in the program. Sandra L. Jackson,...
Chicago—An analysis of a large...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—After 26 weeks of treatment, patients with type 2 diabetes who received dulaglutide once weekly had a statistically significant reduction in hemoglobin A1c (HbA1c) levels compared with a placebo group and patients who took exenatide,...
Chicago—After 26 weeks of treatment, patients with type 2 diabetes who received dulaglutide once weekly had a statistically significant reduction in hemoglobin A1c (HbA1c) levels compared with a placebo group and patients who took exenatide,...
Chicago—After 26 weeks of...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—According to a randomized, open-label, phase 3 trial, patients with type 2 diabetes who received a combination of liraglutide and insulin degludec had significant reductions in hemoglobin A1c (HbA1c) levels after 26 weeks compared...
Chicago—According to a randomized, open-label, phase 3 trial, patients with type 2 diabetes who received a combination of liraglutide and insulin degludec had significant reductions in hemoglobin A1c (HbA1c) levels after 26 weeks compared...
Chicago—According to a...
08/15/2013
First Report Managed Care
08/15/2013
Tim Casey
Chicago—After 104 weeks of treatment, patients with type 2 diabetes who received albiglutide in combination with metformin had statistically and clinically significant glucose reductions compared with patients who took sitagliptin,...
Chicago—After 104 weeks of treatment, patients with type 2 diabetes who received albiglutide in combination with metformin had statistically and clinically significant glucose reductions compared with patients who took sitagliptin,...
Chicago—After 104 weeks of...
08/15/2013
First Report Managed Care
08/14/2013
Tim Casey
A trial of obese patients with type 2 diabetes found that Roux-en-Y gastric bypass surgery had greater weight loss than management programs. 
A trial of obese patients with type 2 diabetes found that Roux-en-Y gastric bypass surgery had greater weight loss than management programs. 
A trial of obese patients with...
08/14/2013
First Report Managed Care
News Connection
08/14/2013
Tori Socha
One of the provisions of the Patient Protection and Affordable Care Act (ACA) became effective on September 23, 2010. As of that date and in all states, all adults between 19 and 25 years of age are eligible for health insurance coverage...
One of the provisions of the Patient Protection and Affordable Care Act (ACA) became effective on September 23, 2010. As of that date and in all states, all adults between 19 and 25 years of age are eligible for health insurance coverage...
One of the provisions of the...
08/14/2013
First Report Managed Care
News Connection
08/14/2013
Tori Socha
Older adults admitted to the hospital for acute medical problems are at risk for adverse events both during and after the hospitalization. Possible events include pressure ulcers, falls, hospital-acquired infections, functional decline,...
Older adults admitted to the hospital for acute medical problems are at risk for adverse events both during and after the hospitalization. Possible events include pressure ulcers, falls, hospital-acquired infections, functional decline,...
Older adults admitted to the...
08/14/2013
First Report Managed Care
08/14/2013
Tori Socha
Noting a lack of data required to correctly identify the characteristics of current oncology trials and the ability of those trials to advance care, researchers recently conducted a comprehensive analysis of the national oncology clinical...
Noting a lack of data required to correctly identify the characteristics of current oncology trials and the ability of those trials to advance care, researchers recently conducted a comprehensive analysis of the national oncology clinical...
Noting a lack of data required...
08/14/2013
First Report Managed Care
08/14/2013
Tori Socha
The incidence of sarcoidosis, a multisystem granulomatous disease of unclear etiology, is, according to researchers, high, with up to 40 cases per 100,000 individuals. In addition, mortality related to sarcoidosis is increasing. The disease...
The incidence of sarcoidosis, a multisystem granulomatous disease of unclear etiology, is, according to researchers, high, with up to 40 cases per 100,000 individuals. In addition, mortality related to sarcoidosis is increasing. The disease...
The incidence of sarcoidosis, a...
08/14/2013
First Report Managed Care
News Connection
08/14/2013


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Tori Socha

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Despite concerns that the Patient Protection and Affordable Care Act would lead to reductions in Medicare Advantage (MA) plan enrollments, 14.4 million Americans were enrolled in a MA plan as of March 2013, an increase of >12 million over...
Despite concerns that the Patient Protection and Affordable Care Act would lead to reductions in Medicare Advantage (MA) plan enrollments, 14.4 million Americans were enrolled in a MA plan as of March 2013, an increase of >12 million over...
Despite concerns that the...
08/14/2013
First Report Managed Care
08/14/2013
Tori Socha
For patients with Parkinson disease (PD), access to care may be limited by distance, disability, and distribution of physicians. It is estimated that 40% of Medicare beneficiaries with PD have not seen a neurologist.
For patients with Parkinson disease (PD), access to care may be limited by distance, disability, and distribution of physicians. It is estimated that 40% of Medicare beneficiaries with PD have not seen a neurologist.
For patients with Parkinson...
08/14/2013
First Report Managed Care
08/14/2013
Tori Socha
Prostate-specific antigen (PSA) screening in older men, including those with serious comorbidity, is common practice in spite of recommendations against PSA screening in that population. The recommendations against PSA screening in men with...
Prostate-specific antigen (PSA) screening in older men, including those with serious comorbidity, is common practice in spite of recommendations against PSA screening in that population. The recommendations against PSA screening in men with...
Prostate-specific antigen (PSA)...
08/14/2013
First Report Managed Care
08/14/2013
Tori Socha
Studies show that intensivist physicians improve patient outcomes in intensive care units (ICUs).
Studies show that intensivist physicians improve patient outcomes in intensive care units (ICUs).
Studies show that intensivist...
08/14/2013
First Report Managed Care
08/14/2013
Tori Socha
According to researchers, most elderly patients prefer only comfort measures at the end of life (EOL); however, clinicians are increasingly using life-sustaining technologies in a patient’s final stages. Whereas most people express a desire...
According to researchers, most elderly patients prefer only comfort measures at the end of life (EOL); however, clinicians are increasingly using life-sustaining technologies in a patient’s final stages. Whereas most people express a desire...
According to researchers, most...
08/14/2013
First Report Managed Care
08/14/2013
Tori Socha
The most common malignant neoplasm in American men is prostate cancer; there are 240,000 cases of prostate cancer and 30,000 deaths from the disease per year. Emerging technologies such as intensity-modulated radiotherapy (IMRT) have been...
The most common malignant neoplasm in American men is prostate cancer; there are 240,000 cases of prostate cancer and 30,000 deaths from the disease per year. Emerging technologies such as intensity-modulated radiotherapy (IMRT) have been...
The most common malignant...
08/14/2013
First Report Managed Care
News Connection
08/14/2013
Tim Casey
Soon after the American Medical Association (AMA) announced last year its plan to enhance physician satisfaction and practice sustainability, AMA chief executive officer James Madara, MD, received complaints from outside the medical...
Soon after the American Medical Association (AMA) announced last year its plan to enhance physician satisfaction and practice sustainability, AMA chief executive officer James Madara, MD, received complaints from outside the medical...
Soon after the American Medical...
08/14/2013
First Report Managed Care
News Connection
08/14/2013
Tim Casey
Through his academic training and work experience, Shivan Mehta, MD, MBA, understands better than most people the clinical and business aspects of medicine. Dr. Mehta, a practicing gastroenterologist, is also director of operations at the...
Through his academic training and work experience, Shivan Mehta, MD, MBA, understands better than most people the clinical and business aspects of medicine. Dr. Mehta, a practicing gastroenterologist, is also director of operations at the...
Through his academic training...
08/14/2013
First Report Managed Care