Stenting Improves Long-Term Survival for Patients With Complete Blockages Undergoing PCI
New Data Demonstrates Lower Risk of Cardiovascular Death at Six Months and Lower Incidence of Cardiac Arrest at One Year Compared to Non-Stenting
New Data Demonstrates Lower Risk of Cardiovascular Death at Six Months and Lower Incidence of Cardiac Arrest at One Year Compared to Non-Stenting
Society for Cardiovascular Angiography & Interventions (SCAI) News
WASHINGTON, D.C. — In patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI), stenting demonstrated improved long-term survival and fewer cardiac arrests at one year. The late-breaking data were presented May 1 at the Society for Cardiovascular Angiography & Interventions (SCAI) 2025 Scientific Sessions.
Coronary artery disease (CAD) is the most common type of heart disease and a leading cause of death worldwide. CTO PCI is a minimally invasive procedure to treat CAD by reopening blocked arteries with a catheter and stent. CTO PCI is a challenging procedure and has been associated with lower success and higher in-hospital event rates compared to non-CTO PCI. The decision to place a stent may significantly impact clinical outcomes. While stenting improves blood vessel blockage or obstruction, the long-term benefits of stenting in CTO PCI remain debated.
The retrospective, single-center observational study evaluated the association between stented versus non-stented CTOs at a high-volume PCI center. Patients were stratified into stented and non-stented groups. Baseline characteristics were assessed using descriptive statistics.
A total of 677 patients underwent CTO PCI, with 81.2% receiving stents. Stenting was associated with improved long-term outcomes, including a lower risk of cardiovascular death at six months (adjusted odds ratio 0.20, 95% confidence interval 0.06–0.71) and a lower incidence of cardiac arrest at one year (adjusted odds ratio 0.21, 95% confidence interval 0.06–0.72). No significant differences were observed in 30-day all-cause mortality or in-hospital complications.
“While stenting is widely accepted as beneficial for patients with total blockages, the data presented at SCAI Scientific Sessions provides further evidence that it should be considered safe and effective in the long term,” said M Chadi Alraies, MD, MPH, FACC, FSCAI, Clinical Associate Professor of Medicine at Wayne State University School of Medicine, Medical Director Cardiac Catheterization Lab at Detroit Medical Center in Detroit, Mich. and lead author of the study. “Our study provides evidence that stenting can be an important treatment option for patients undergoing CTO PCI.”
The authors note that further studies are needed to refine treatment strategies and optimize CTO PCI outcomes.
Session Details:
- “Clinical Outcomes of Stented vs. Non-Stented Chronic Total Occlusion Patients”
- Thursday, May 1, 2025; 11:17-11:25 AM ET
- Walter E. Washington Convention Center, Exhibit Hall D
About SCAI Scientific Sessions 2025
The SCAI Scientific Sessions annual meeting convenes 2,000 of the world’s premier clinicians, scientists, researchers, and innovators in the field of interventional cardiology and endovascular medicine. With 500+ faculty and hundreds of abstracts, experts in the field work together to share the latest clinical data, procedural guidance, and advanced expertise. Highlights will include live cases, featured clinical research, new SCAI clinical documents, case-based learning, and keynote speakers. For more information, visit SCAI 2025 Scientific Sessions | SCAI.
About Society for Cardiovascular Angiography & Interventions (SCAI)
The Society for Cardiovascular Angiography & Interventions, established in 1978, stands as the primary nonprofit medical society dedicated to representing invasive and interventional cardiology. SCAI's mission is to guide the global interventional cardiovascular community by fostering education, advocacy, research, and upholding standards for quality patient care. For more than 40 years, SCAI has exemplified professional excellence and innovation worldwide, cultivating a reputable community of over 5,000 members committed to advancing medical science and providing life-saving care for individuals, both adults and children, affected by cardiovascular disease. For more information, visit SCAI.ORG.
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