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Hereditary Angioedema Topic Center

Research Summary
Barriers to Normalization Persist for U.S. Patients With Hereditary Angioedema
01/18/2026
Rebecca Mashaw
New survey data highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among patients being treated for hereditary angioedema.
New survey data highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among patients being treated for hereditary angioedema.
New survey data highlight...
01/18/2026
Allergy & Immunology
Research Highlights
Updated International Consensus on HAE-nC1INH Diagnosis and Treatment
01/16/2026
Rebecca Mashaw
The 2025 global consensus represents a major step forward in unifying global expert opinion on HAE-nC1INH diagnosis and care.
The 2025 global consensus represents a major step forward in unifying global expert opinion on HAE-nC1INH diagnosis and care.
The 2025 global consensus...
01/16/2026
Allergy & Immunology
Patient Survey
Barriers to Normalization Persist for U.S. Patients With Hereditary Angioedema
01/16/2026
Rebecca Mashaw
New survey data published in Annals of Allergy, Asthma, and Immunology highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among treated patients.
New survey data published in Annals of Allergy, Asthma, and Immunology highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among treated patients.
New survey data published in...
01/16/2026
Allergy & Immunology
Quiz
Therapeutic Innovations in HAE
01/11/2026
Do you know about the most recent advances in therapies for hereditary angioedema? Take our quiz to test your knowledge!
Do you know about the most recent advances in therapies for hereditary angioedema? Take our quiz to test your knowledge!
Do you know about the most...
01/11/2026
Allergy & Immunology
Research Highlights
Elevated Comorbidity Burden and Surgical Interventions in Patients With HAE-C1INH
12/06/2025
Jessica Garlewicz
Study findings underscore the need for heightened clinical surveillance and early recognition to avoid unnecessary procedures and improve long-term patient outcomes.
Study findings underscore the need for heightened clinical surveillance and early recognition to avoid unnecessary procedures and improve long-term patient outcomes.
Study findings underscore the...
12/06/2025
Allergy & Immunology
Patient-Reported Outcomes
Injectable On-Demand HAE Treatments Undermine Quality of Life, Study Finds
12/06/2025
Jessica Garlewicz
This analysis highlights the persistent challenges that impact health-related quality of life (HRQoL) across emotional, social, and practical domains.
This analysis highlights the persistent challenges that impact health-related quality of life (HRQoL) across emotional, social, and practical domains.
This analysis highlights the...
12/06/2025
Allergy & Immunology
Emerging Therapies
Advances in HAE Therapeutics Highlight Path Toward Personalized, Patient-Centered Care
12/06/2025
Jessica Garlewicz
The future of HAE management will likely focus on tailoring regimens to patient-specific needs, attack phenotypes, and treatment goals.
The future of HAE management will likely focus on tailoring regimens to patient-specific needs, attack phenotypes, and treatment goals.
The future of HAE management...
12/06/2025
Allergy & Immunology
Clinical Trials
Deucrictibant Demonstrates Durable Efficacy and Safety in Long-Term Prophylaxis of Hereditary Angioedema
11/13/2025
Jessica Garlewicz
Interim results from the open-label extension of the CHAPTER-1 phase 2 trial support the long-term efficacy and safety of deucrictibant, an oral bradykinin B2 receptor antagonist, for hereditary angioedema prophylaxis
Interim results from the open-label extension of the CHAPTER-1 phase 2 trial support the long-term efficacy and safety of deucrictibant, an oral bradykinin B2 receptor antagonist, for hereditary angioedema prophylaxis
Interim results from the...
11/13/2025
Allergy & Immunology

In the News

Research Summary
Barriers to Normalization Persist for U.S. Patients With Hereditary Angioedema
01/18/2026
Rebecca Mashaw
New survey data highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among patients being treated for hereditary angioedema.
New survey data highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among patients being treated for hereditary angioedema.
New survey data highlight...
01/18/2026
Allergy & Immunology
Research Highlights
Elevated Comorbidity Burden and Surgical Interventions in Patients With HAE-C1INH
12/06/2025
Jessica Garlewicz
Study findings underscore the need for heightened clinical surveillance and early recognition to avoid unnecessary procedures and improve long-term patient outcomes.
Study findings underscore the need for heightened clinical surveillance and early recognition to avoid unnecessary procedures and improve long-term patient outcomes.
Study findings underscore the...
12/06/2025
Allergy & Immunology
Emerging Therapies
Advances in HAE Therapeutics Highlight Path Toward Personalized, Patient-Centered Care
12/06/2025
Jessica Garlewicz
The future of HAE management will likely focus on tailoring regimens to patient-specific needs, attack phenotypes, and treatment goals.
The future of HAE management will likely focus on tailoring regimens to patient-specific needs, attack phenotypes, and treatment goals.
The future of HAE management...
12/06/2025
Allergy & Immunology
Clinical Trials
Deucrictibant Demonstrates Durable Efficacy and Safety in Long-Term Prophylaxis of Hereditary Angioedema
11/13/2025
Jessica Garlewicz
Interim results from the open-label extension of the CHAPTER-1 phase 2 trial support the long-term efficacy and safety of deucrictibant, an oral bradykinin B2 receptor antagonist, for hereditary angioedema prophylaxis
Interim results from the open-label extension of the CHAPTER-1 phase 2 trial support the long-term efficacy and safety of deucrictibant, an oral bradykinin B2 receptor antagonist, for hereditary angioedema prophylaxis
Interim results from the...
11/13/2025
Allergy & Immunology
Research Review
MDD in Asthma Patients Associated With Worse Outcomes in Older Adults
01/29/2026
Rebecca Mashaw
A recent cohort study by highlights how psychological health influences asthma control and healthcare utilization, underscoring a need for integrated care in older populations.
A recent cohort study by highlights how psychological health influences asthma control and healthcare utilization, underscoring a need for integrated care in older populations.
A recent cohort study by...
01/29/2026
Allergy & Immunology
Research Summary
Barriers to Normalization Persist for U.S. Patients With Hereditary Angioedema
01/18/2026
Rebecca Mashaw
New survey data highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among patients being treated for hereditary angioedema.
New survey data highlight persistent disease burden, frequent attacks, and widespread concern about lifelong medication use among patients being treated for hereditary angioedema.
New survey data highlight...
01/18/2026
Allergy & Immunology
Comorbidities
Oscillometry-Based Markers Reveal Airway Dynamics in Asthma–OSA Overlap
12/06/2025
Jessica Garlewicz
While the exact mechanistic interactions remain complex, oscillometric patterns provided insight into changes in respiratory rhythm and resistance related to nocturnal airway collapse and remodeling.
While the exact mechanistic interactions remain complex, oscillometric patterns provided insight into changes in respiratory rhythm and resistance related to nocturnal airway collapse and remodeling.
While the exact mechanistic...
12/06/2025
Allergy & Immunology
Morbidity & Mortality
Mortality From Coexisting Asthma and Cardiovascular Disease Rising
12/06/2025
Jessica Garlewicz
This analysis found significant disparities in mortality across demographic groups.
This analysis found significant disparities in mortality across demographic groups.
This analysis found significant...
12/06/2025
Allergy & Immunology
Research Highlights
Elevated Comorbidity Burden and Surgical Interventions in Patients With HAE-C1INH
12/06/2025
Jessica Garlewicz
Study findings underscore the need for heightened clinical surveillance and early recognition to avoid unnecessary procedures and improve long-term patient outcomes.
Study findings underscore the need for heightened clinical surveillance and early recognition to avoid unnecessary procedures and improve long-term patient outcomes.
Study findings underscore the...
12/06/2025
Allergy & Immunology
Emerging Therapies
Advances in HAE Therapeutics Highlight Path Toward Personalized, Patient-Centered Care
12/06/2025
Jessica Garlewicz
The future of HAE management will likely focus on tailoring regimens to patient-specific needs, attack phenotypes, and treatment goals.
The future of HAE management will likely focus on tailoring regimens to patient-specific needs, attack phenotypes, and treatment goals.
The future of HAE management...
12/06/2025
Allergy & Immunology
News
Blastocystis Colonization Alters Gut Microbiota in Patients With Urticaria
12/06/2025
Jessica Garlewicz
New evidence suggests that blastocystis infection may contribute to immune dysregulation in urticaria through alterations in the intestinal microbiota.
New evidence suggests that blastocystis infection may contribute to immune dysregulation in urticaria through alterations in the intestinal microbiota.
New evidence suggests that...
12/06/2025
Allergy & Immunology
News
Outpatient Study Highlights Effectiveness of Penicillin Allergy Delabeling via Oral Challenge
11/17/2025
Jessica Garlewicz
A retrospective chart review conducted at an outpatient allergy clinic found that oral drug challenges are safe and highly effective for penicillin allergy delabeling.
A retrospective chart review conducted at an outpatient allergy clinic found that oral drug challenges are safe and highly effective for penicillin allergy delabeling.
A retrospective chart review...
11/17/2025
Allergy & Immunology
News
Cephalosporin Allergy Evaluation Improves Antibiotic Stewardship in Immunocompromised Inpatients
11/17/2025
Jessica Garlewicz
A targeted inpatient allergy consult service employing risk stratification and drug provocation testing significantly improved antibiotic stewardship by safely de-labeling cephalosporin allergies in immunocompromised patients.
A targeted inpatient allergy consult service employing risk stratification and drug provocation testing significantly improved antibiotic stewardship by safely de-labeling cephalosporin allergies in immunocompromised patients.
A targeted inpatient allergy...
11/17/2025
Allergy & Immunology
News
Drug-Related Anaphylaxis Mortality Remains Stable but Disparities Persist
11/13/2025
Jessica Garlewicz
A new national analysis of death certificate data from 2011 to 2023 reveals that drug-related anaphylaxis continues to be a significant contributor to anaphylaxis-related deaths in the United States, particularly among older adults and...
A new national analysis of death certificate data from 2011 to 2023 reveals that drug-related anaphylaxis continues to be a significant contributor to anaphylaxis-related deaths in the United States, particularly among older adults and...
A new national analysis of death...
11/13/2025
Allergy & Immunology

Popular Articles

News
FDA Approves Budesonide Oral Suspension for EoE
02/28/2024
Rebecca Mashaw
The approval marks the first and only oral therapy for patients 11 and older with eosinophilic esophagitis.
The approval marks the first and only oral therapy for patients 11 and older with eosinophilic esophagitis.
The approval marks the first and...
02/28/2024
Gastroenterology
Allergen Focus
Photoallergic Contact Dermatitis
03/06/2024
Caroline Brumley, BS; Sara A. Hylwa, MD
Recognizing and testing for this rare but important photodermatosis are keys to alleviating patient distress.
Recognizing and testing for this rare but important photodermatosis are keys to alleviating patient distress.
Recognizing and testing for this...
03/06/2024
The Dermatologist
Conference Coverage
Plasma-Guided Adaptive Chemoimmunotherapy for Patients With First-Line Non-Small Cell Lung Cancer
05/27/2025
Allison Casey
According to a prospective clinical trial, the use of plasma-guided adaptive treatment led to a median progression-free survival comparable to historical controls for patients with advanced PD-L1–positive non-small cell lung cancer.
According to a prospective clinical trial, the use of plasma-guided adaptive treatment led to a median progression-free survival comparable to historical controls for patients with advanced PD-L1–positive non-small cell lung cancer.
According to a prospective...
05/27/2025
Oncology
Research Highlights
Updated International Consensus on HAE-nC1INH Diagnosis and Treatment
01/16/2026
Rebecca Mashaw
The 2025 global consensus represents a major step forward in unifying global expert opinion on HAE-nC1INH diagnosis and care.
The 2025 global consensus represents a major step forward in unifying global expert opinion on HAE-nC1INH diagnosis and care.
The 2025 global consensus...
01/16/2026
Allergy & Immunology
News
Cephalosporin Allergy Evaluation Improves Antibiotic Stewardship in Immunocompromised Inpatients
11/17/2025
Jessica Garlewicz
A targeted inpatient allergy consult service employing risk stratification and drug provocation testing significantly improved antibiotic stewardship by safely de-labeling cephalosporin allergies in immunocompromised patients.
A targeted inpatient allergy consult service employing risk stratification and drug provocation testing significantly improved antibiotic stewardship by safely de-labeling cephalosporin allergies in immunocompromised patients.
A targeted inpatient allergy...
11/17/2025
Allergy & Immunology

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