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Type 2 Inflammation Learning Library

Featured Video

Mona Shahriari
Rapid Refresh
10/15/2025
Mona Shahriari, MD, FAAD
Dr Mona Shahriari explains how type 2 inflammation drives atopic dermatitis flares, the role of key cytokines like IL-4 and IL-13, and how emerging treatments target this complex immune cascade.
Dr Mona Shahriari explains how type 2 inflammation drives atopic dermatitis flares, the role of key cytokines like IL-4 and IL-13, and how emerging treatments target this complex immune cascade.
Dr Mona Shahriari explains how...
10/15/2025
The Derm APP

Multimedia

jeff cohen
Clinical Pearls
12/01/2025
Jeffrey M. Cohen, MD
Unlock the clinical relevance of type 2 inflammation beyond atopic dermatitis. Dr Jeffrey Cohen explores cytokine pathways, JAK-STAT signaling, and pivotal dupilumab trials for prurigo nodularis, chronic spontaneous urticaria, and bullous...
Unlock the clinical relevance of type 2 inflammation beyond atopic dermatitis. Dr Jeffrey Cohen explores cytokine pathways, JAK-STAT signaling, and pivotal dupilumab trials for prurigo nodularis, chronic spontaneous urticaria, and bullous...
Unlock the clinical relevance of...
12/01/2025
The Derm APP
Mona Shahriari
Rapid Refresh
10/15/2025
Mona Shahriari, MD, FAAD
Dr Mona Shahriari explains how type 2 inflammation drives atopic dermatitis flares, the role of key cytokines like IL-4 and IL-13, and how emerging treatments target this complex immune cascade.
Dr Mona Shahriari explains how type 2 inflammation drives atopic dermatitis flares, the role of key cytokines like IL-4 and IL-13, and how emerging treatments target this complex immune cascade.
Dr Mona Shahriari explains how...
10/15/2025
The Derm APP
Kimberly McPeeks
Clinical Pearls
09/15/2025
Kimberly Kincaid McPeeks, MPAS, PA-C
NCCPA-certified physician assistant Kimberly McPeaks explores key differences between irritant and allergic contact dermatitis. Learn when to use patch testing, and get tips on patient education and management.
NCCPA-certified physician assistant Kimberly McPeaks explores key differences between irritant and allergic contact dermatitis. Learn when to use patch testing, and get tips on patient education and management.
NCCPA-certified physician...
09/15/2025
The Derm APP
Vivian Shi
Rapid Refresh
08/15/2025
Vivian Shi, MD
Dr Vivian Shi explores the burden of head and neck eczema, common triggers, and key diagnostic clues to distinguish atopic dermatitis from its mimickers.
Dr Vivian Shi explores the burden of head and neck eczema, common triggers, and key diagnostic clues to distinguish atopic dermatitis from its mimickers.
Dr Vivian Shi explores the...
08/15/2025
The Derm APP
Daniel Butler
Rapid Refresh
07/15/2025
Daniel C. Butler, MD
Dr Daniel Butler explores the role of Th2 immunity in dermatology. Learn about Th2-mediated skin diseases like atopic dermatitis and chronic spontaneous urticaria, cutting-edge biologics, JAK inhibitors, and best practices for patient...
Dr Daniel Butler explores the role of Th2 immunity in dermatology. Learn about Th2-mediated skin diseases like atopic dermatitis and chronic spontaneous urticaria, cutting-edge biologics, JAK inhibitors, and best practices for patient...
Dr Daniel Butler explores the...
07/15/2025
The Derm APP
Lakshi Aldredge
Rapid Refresh
06/15/2025
Lakshi Aldredge, NP
Dermatology NP Lakshee Aldridge explores type 2 inflammation, its role in atopic dermatitis and prurigo nodularis, and how IL-4, IL-13, and IL-31-targeted therapies restore immune balance and improve patient outcomes.
Dermatology NP Lakshee Aldridge explores type 2 inflammation, its role in atopic dermatitis and prurigo nodularis, and how IL-4, IL-13, and IL-31-targeted therapies restore immune balance and improve patient outcomes.
Dermatology NP Lakshee Aldridge...
06/15/2025
The Derm APP
Steven R. Feldman, MD, PhD
Clinical Pearls
05/15/2025
Steven R. Feldman, MD, PhD
Poor adherence to topical treatments is a major barrier in managing atopic dermatitis.
Poor adherence to topical treatments is a major barrier in managing atopic dermatitis.
Poor adherence to topical...
05/15/2025
The Derm APP
Lauren McGrath
Clinical Pearls
04/15/2025
Lauren McGrath
Explore new systemic treatments for type 2 inflammation in atopic dermatitis, including lebrikizumab, nemolizumab, upadacitinib, and dupilumab.
Explore new systemic treatments for type 2 inflammation in atopic dermatitis, including lebrikizumab, nemolizumab, upadacitinib, and dupilumab.
Explore new systemic treatments...
04/15/2025
The Derm APP
Lauren McGrath
Clinical Pearls
03/15/2025
Lauren McGrath
Explore the latest topical therapies for type 2 inflammation in atopic dermatitis, including tapinarof, roflumilast, and ruxolitinib creams.
Explore the latest topical therapies for type 2 inflammation in atopic dermatitis, including tapinarof, roflumilast, and ruxolitinib creams.
Explore the latest topical...
03/15/2025
The Derm APP
Peter Lio
Clinical Pearls
02/12/2025
Peter Lio, MD, FAAD
Dr Peter Lio explores the link between environmental factors, such as pollution and lifestyle changes, and the rise of atopic dermatitis and type 2 inflammation.
Dr Peter Lio explores the link between environmental factors, such as pollution and lifestyle changes, and the rise of atopic dermatitis and type 2 inflammation.
Dr Peter Lio explores the link...
02/12/2025
The Derm APP
jeff cohen
Clinical Pearls
12/01/2025
Jeffrey M. Cohen, MD
Unlock the clinical relevance of type 2 inflammation beyond atopic dermatitis. Dr Jeffrey Cohen explores cytokine pathways, JAK-STAT signaling, and pivotal dupilumab trials for prurigo nodularis, chronic spontaneous urticaria, and bullous...
Unlock the clinical relevance of type 2 inflammation beyond atopic dermatitis. Dr Jeffrey Cohen explores cytokine pathways, JAK-STAT signaling, and pivotal dupilumab trials for prurigo nodularis, chronic spontaneous urticaria, and bullous...
Unlock the clinical relevance of...
12/01/2025
The Derm APP
Mona Shahriari
Rapid Refresh
10/15/2025
Mona Shahriari, MD, FAAD
Dr Mona Shahriari explains how type 2 inflammation drives atopic dermatitis flares, the role of key cytokines like IL-4 and IL-13, and how emerging treatments target this complex immune cascade.
Dr Mona Shahriari explains how type 2 inflammation drives atopic dermatitis flares, the role of key cytokines like IL-4 and IL-13, and how emerging treatments target this complex immune cascade.
Dr Mona Shahriari explains how...
10/15/2025
The Derm APP
Celebrate PA Week
APP Perspectives
10/08/2025
Coleen Stern, MA
Celebrate PA Week, October 6 to 12, 2025.
Celebrate PA Week, October 6 to 12, 2025.
Celebrate PA Week, October 6 to...
10/08/2025
The Derm APP
Andrea Nguyen
Clinical Pearls
09/25/2025
Andrea Nguyen, DMSc, MPAS, PA-C
Explore how NPs and PAs can overcome access barriers and support individualized care for patients with vitiligo.
Explore how NPs and PAs can overcome access barriers and support individualized care for patients with vitiligo.
Explore how NPs and PAs can...
09/25/2025
The Derm APP
Kimberly McPeeks
Clinical Pearls
09/15/2025
Kimberly Kincaid McPeeks, MPAS, PA-C
NCCPA-certified physician assistant Kimberly McPeaks explores key differences between irritant and allergic contact dermatitis. Learn when to use patch testing, and get tips on patient education and management.
NCCPA-certified physician assistant Kimberly McPeaks explores key differences between irritant and allergic contact dermatitis. Learn when to use patch testing, and get tips on patient education and management.
NCCPA-certified physician...
09/15/2025
The Derm APP
Peggy Vernon
Clinical Pearls
09/05/2025
Peggy Vernon, RN, MA, CPNP, DCNP, FAANP
A review of topical treatments for pediatric atopic dermatitis, from calcineurin inhibitors to newer options like crisaborole and ruxolitinib.
A review of topical treatments for pediatric atopic dermatitis, from calcineurin inhibitors to newer options like crisaborole and ruxolitinib.
A review of topical treatments...
09/05/2025
The Derm APP
Peter Lio
Clinical Pearls
08/25/2025
Peter Lio, MD, FAAD
Integrative medicine bridges conventional treatments with complementary approaches, offering a holistic, patient-centered strategy for dermatologic care.
Integrative medicine bridges conventional treatments with complementary approaches, offering a holistic, patient-centered strategy for dermatologic care.
Integrative medicine bridges...
08/25/2025
The Derm APP
Vivian Shi
Rapid Refresh
08/15/2025
Vivian Shi, MD
Dr Vivian Shi explores the burden of head and neck eczema, common triggers, and key diagnostic clues to distinguish atopic dermatitis from its mimickers.
Dr Vivian Shi explores the burden of head and neck eczema, common triggers, and key diagnostic clues to distinguish atopic dermatitis from its mimickers.
Dr Vivian Shi explores the...
08/15/2025
The Derm APP
Jeffrey M. Cohen, MD
Clinical Pearls
08/05/2025
Jeffrey M. Cohen, MD
Dr Cohen examines the complex relationship between psoriasis and multiple sclerosis (MS), focusing on the impact of TNF-alpha inhibitors.
Dr Cohen examines the complex relationship between psoriasis and multiple sclerosis (MS), focusing on the impact of TNF-alpha inhibitors.
Dr Cohen examines the complex...
08/05/2025
The Derm APP
David Rosmarin
Rapid Refresh
07/25/2025
David Rosmarin, MD
Learn to distinguish between segmental and non-segmental vitiligo, identify signs of active disease, and explore clinical features like confetti depigmentation, trichrome patterns, and Koebner phenomenon in this detailed breakdown.
Learn to distinguish between segmental and non-segmental vitiligo, identify signs of active disease, and explore clinical features like confetti depigmentation, trichrome patterns, and Koebner phenomenon in this detailed breakdown.
Learn to distinguish between...
07/25/2025
The Derm APP

News

doctors
News
06/20/2025
Riya Gandhi, MA
Could a targeted biologic therapy change the treatment landscape for COPD patients with type 2 inflammation?
Could a targeted biologic therapy change the treatment landscape for COPD patients with type 2 inflammation?
Could a targeted biologic...
06/20/2025
The Derm APP
children
News
05/28/2025
Riya Gandhi, MA
A long-term study shows that dupilumab significantly reduces asthma exacerbations in children with type 2 asthma, offering sustained benefits for both allergic and non-allergic patients.
A long-term study shows that dupilumab significantly reduces asthma exacerbations in children with type 2 asthma, offering sustained benefits for both allergic and non-allergic patients.
A long-term study shows that...
05/28/2025
The Derm APP
AD
News
04/10/2025
Riya Gandhi, MA
A new study finds that dupilumab significantly improves eczema symptoms in young children, whether they have asthma, allergic rhinitis, or food allergies.
A new study finds that dupilumab significantly improves eczema symptoms in young children, whether they have asthma, allergic rhinitis, or food allergies.
A new study finds that dupilumab...
04/10/2025
The Derm APP
telemedicine
News
02/24/2025
Riya Gandhi, MA
A new study reveals distinct inflammatory and fibrotic signatures in localized scleroderma, highlighting the role of adaptive immunity and potential therapeutic targets.
A new study reveals distinct inflammatory and fibrotic signatures in localized scleroderma, highlighting the role of adaptive immunity and potential therapeutic targets.
A new study reveals distinct...
02/24/2025
The Derm APP
contact dermtitis + Neck + Eczema + rash
News
02/14/2025
Riya Gandhi, MA
A study highlights the broad anti-inflammatory effects of dupilumab in prurigo nodularis, with potential implications for addressing systemic disease comorbidities.
A study highlights the broad anti-inflammatory effects of dupilumab in prurigo nodularis, with potential implications for addressing systemic disease comorbidities.
A study highlights the broad...
02/14/2025
The Derm APP
SOC
News
01/29/2025
Riya Gandhi, MA
New findings uncover the role of immune triggers, including vaccines and therapies, in chronic pruritus and its association with heightened type 2 inflammation markers.
New findings uncover the role of immune triggers, including vaccines and therapies, in chronic pruritus and its association with heightened type 2 inflammation markers.
New findings uncover the role of...
01/29/2025
The Derm APP
Atopic dermatitis
News
01/17/2025
Riya Gandhi, MA
New research highlights the safety benefits of dupilumab over traditional immunosuppressants in reducing upper respiratory infection risks for patients with moderate-to-severe atopic dermatitis.
New research highlights the safety benefits of dupilumab over traditional immunosuppressants in reducing upper respiratory infection risks for patients with moderate-to-severe atopic dermatitis.
New research highlights the...
01/17/2025
The Derm APP
Atopic dermatitis
News
01/07/2025
Riya Gandhi, MA
A groundbreaking questionnaire aims to address the unmet need for timely detection and referral of coexisting type 2 inflammation-related diseases, bridging gaps in interdisciplinary care.
A groundbreaking questionnaire aims to address the unmet need for timely detection and referral of coexisting type 2 inflammation-related diseases, bridging gaps in interdisciplinary care.
A groundbreaking questionnaire...
01/07/2025
The Derm APP
doctors
News
06/20/2025
Riya Gandhi, MA
Could a targeted biologic therapy change the treatment landscape for COPD patients with type 2 inflammation?
Could a targeted biologic therapy change the treatment landscape for COPD patients with type 2 inflammation?
Could a targeted biologic...
06/20/2025
The Derm APP
children
News
05/28/2025
Riya Gandhi, MA
A long-term study shows that dupilumab significantly reduces asthma exacerbations in children with type 2 asthma, offering sustained benefits for both allergic and non-allergic patients.
A long-term study shows that dupilumab significantly reduces asthma exacerbations in children with type 2 asthma, offering sustained benefits for both allergic and non-allergic patients.
A long-term study shows that...
05/28/2025
The Derm APP
AD
News
04/10/2025
Riya Gandhi, MA
A new study finds that dupilumab significantly improves eczema symptoms in young children, whether they have asthma, allergic rhinitis, or food allergies.
A new study finds that dupilumab significantly improves eczema symptoms in young children, whether they have asthma, allergic rhinitis, or food allergies.
A new study finds that dupilumab...
04/10/2025
The Derm APP
telemedicine
News
02/24/2025
Riya Gandhi, MA
A new study reveals distinct inflammatory and fibrotic signatures in localized scleroderma, highlighting the role of adaptive immunity and potential therapeutic targets.
A new study reveals distinct inflammatory and fibrotic signatures in localized scleroderma, highlighting the role of adaptive immunity and potential therapeutic targets.
A new study reveals distinct...
02/24/2025
The Derm APP
contact dermtitis + Neck + Eczema + rash
News
02/14/2025
Riya Gandhi, MA
A study highlights the broad anti-inflammatory effects of dupilumab in prurigo nodularis, with potential implications for addressing systemic disease comorbidities.
A study highlights the broad anti-inflammatory effects of dupilumab in prurigo nodularis, with potential implications for addressing systemic disease comorbidities.
A study highlights the broad...
02/14/2025
The Derm APP
SOC
News
01/29/2025
Riya Gandhi, MA
New findings uncover the role of immune triggers, including vaccines and therapies, in chronic pruritus and its association with heightened type 2 inflammation markers.
New findings uncover the role of immune triggers, including vaccines and therapies, in chronic pruritus and its association with heightened type 2 inflammation markers.
New findings uncover the role of...
01/29/2025
The Derm APP
Atopic dermatitis
News
01/17/2025
Riya Gandhi, MA
New research highlights the safety benefits of dupilumab over traditional immunosuppressants in reducing upper respiratory infection risks for patients with moderate-to-severe atopic dermatitis.
New research highlights the safety benefits of dupilumab over traditional immunosuppressants in reducing upper respiratory infection risks for patients with moderate-to-severe atopic dermatitis.
New research highlights the...
01/17/2025
The Derm APP
Atopic dermatitis
News
01/07/2025
Riya Gandhi, MA
A groundbreaking questionnaire aims to address the unmet need for timely detection and referral of coexisting type 2 inflammation-related diseases, bridging gaps in interdisciplinary care.
A groundbreaking questionnaire aims to address the unmet need for timely detection and referral of coexisting type 2 inflammation-related diseases, bridging gaps in interdisciplinary care.
A groundbreaking questionnaire...
01/07/2025
The Derm APP

Quizzes

Quiz
01/01/2026
Riya Gandhi, MA
Dive into kinase dynamics—can you pinpoint the molecular reason behind increased adverse event risk with high-dose JAK inhibitor therapy?
Dive into kinase dynamics—can you pinpoint the molecular reason behind increased adverse event risk with high-dose JAK inhibitor therapy?
Dive into kinase dynamics—can...
01/01/2026
The Dermatologist
Quiz
01/01/2026
Riya Gandhi, MA
Take the quiz to explore how fibroblasts respond to Type 2 cytokines in long-standing AD.
Take the quiz to explore how fibroblasts respond to Type 2 cytokines in long-standing AD.
Take the quiz to explore how...
01/01/2026
The Dermatologist
Quiz
10/25/2025
Riya Gandhi, MA
Quiz yourself on the core mechanistic differences between JAK inhibitors and biologics—do you know which targets are intracellular vs extracellular?
Quiz yourself on the core mechanistic differences between JAK inhibitors and biologics—do you know which targets are intracellular vs extracellular?
Quiz yourself on the core...
10/25/2025
The Derm APP
Quiz
10/25/2025
Riya Gandhi, MA
Test your knowledge of the immune pathways in AD—can you identify which host defense mechanism is disrupted by high levels of IL-4 and IL-13?
Test your knowledge of the immune pathways in AD—can you identify which host defense mechanism is disrupted by high levels of IL-4 and IL-13?
Test your knowledge of the...
10/25/2025
The Derm APP
Quiz
08/27/2025
Riya Gandhi, MA
Flares are only part of the story. Quiz yourself on the chronic Th2 skin conditions.
Flares are only part of the story. Quiz yourself on the chronic Th2 skin conditions.
Flares are only part of the...
08/27/2025
The Derm APP
Quiz
08/20/2025
Riya Gandhi, MA
When is pruritus more than just a symptom? Take the quiz and identify key clinical signs pointing to Th2-driven diseases like prurigo nodularis.
When is pruritus more than just a symptom? Take the quiz and identify key clinical signs pointing to Th2-driven diseases like prurigo nodularis.
When is pruritus more than just...
08/20/2025
The Derm APP
Quiz
08/13/2025
Riya Gandhi, MA
Test your clinical insight on how JAK inhibitors differ from traditional systemic agents like methotrexate.
Test your clinical insight on how JAK inhibitors differ from traditional systemic agents like methotrexate.
Test your clinical insight on...
08/13/2025
The Derm APP
Quiz
08/06/2025
Riya Gandhi, MA
Do you know the rationale behind using biologics like dupilumab in TH2-driven diseases? Quiz yourself on the science behind targeted biologic therapies
Do you know the rationale behind using biologics like dupilumab in TH2-driven diseases? Quiz yourself on the science behind targeted biologic therapies
Do you know the rationale behind...
08/06/2025
The Derm APP
Quiz
08/01/2025
Riya Gandhi, MA
Take the quiz to test your understanding of which immunologic changes define TH2-driven conditions like AD.
Take the quiz to test your understanding of which immunologic changes define TH2-driven conditions like AD.
Take the quiz to test your...
08/01/2025
The Derm APP
Quiz
07/22/2025
Riya Gandhi, MA
Some diagnoses can point toward broader type 2 immune involvement. Quiz yourself on which comorbidities may influence treatment decisions in AD.
Some diagnoses can point toward broader type 2 immune involvement. Quiz yourself on which comorbidities may influence treatment decisions in AD.
Some diagnoses can point toward...
07/22/2025
The Derm APP
Quiz
01/01/2026
Riya Gandhi, MA
Dive into kinase dynamics—can you pinpoint the molecular reason behind increased adverse event risk with high-dose JAK inhibitor therapy?
Dive into kinase dynamics—can you pinpoint the molecular reason behind increased adverse event risk with high-dose JAK inhibitor therapy?
Dive into kinase dynamics—can...
01/01/2026
The Dermatologist
Quiz
01/01/2026
Riya Gandhi, MA
Take the quiz to explore how fibroblasts respond to Type 2 cytokines in long-standing AD.
Take the quiz to explore how fibroblasts respond to Type 2 cytokines in long-standing AD.
Take the quiz to explore how...
01/01/2026
The Dermatologist
Quiz
10/25/2025
Riya Gandhi, MA
Test your knowledge of the immune pathways in AD—can you identify which host defense mechanism is disrupted by high levels of IL-4 and IL-13?
Test your knowledge of the immune pathways in AD—can you identify which host defense mechanism is disrupted by high levels of IL-4 and IL-13?
Test your knowledge of the...
10/25/2025
The Derm APP
Quiz
10/25/2025
Riya Gandhi, MA
Quiz yourself on the core mechanistic differences between JAK inhibitors and biologics—do you know which targets are intracellular vs extracellular?
Quiz yourself on the core mechanistic differences between JAK inhibitors and biologics—do you know which targets are intracellular vs extracellular?
Quiz yourself on the core...
10/25/2025
The Derm APP
Quiz
08/27/2025
Riya Gandhi, MA
Flares are only part of the story. Quiz yourself on the chronic Th2 skin conditions.
Flares are only part of the story. Quiz yourself on the chronic Th2 skin conditions.
Flares are only part of the...
08/27/2025
The Derm APP
Quiz
08/20/2025
Riya Gandhi, MA
When is pruritus more than just a symptom? Take the quiz and identify key clinical signs pointing to Th2-driven diseases like prurigo nodularis.
When is pruritus more than just a symptom? Take the quiz and identify key clinical signs pointing to Th2-driven diseases like prurigo nodularis.
When is pruritus more than just...
08/20/2025
The Derm APP
Quiz
08/13/2025
Riya Gandhi, MA
Test your clinical insight on how JAK inhibitors differ from traditional systemic agents like methotrexate.
Test your clinical insight on how JAK inhibitors differ from traditional systemic agents like methotrexate.
Test your clinical insight on...
08/13/2025
The Derm APP
Quiz
08/06/2025
Riya Gandhi, MA
Do you know the rationale behind using biologics like dupilumab in TH2-driven diseases? Quiz yourself on the science behind targeted biologic therapies
Do you know the rationale behind using biologics like dupilumab in TH2-driven diseases? Quiz yourself on the science behind targeted biologic therapies
Do you know the rationale behind...
08/06/2025
The Derm APP
Quiz
08/01/2025
Riya Gandhi, MA
Take the quiz to test your understanding of which immunologic changes define TH2-driven conditions like AD.
Take the quiz to test your understanding of which immunologic changes define TH2-driven conditions like AD.
Take the quiz to test your...
08/01/2025
The Derm APP
Quiz
07/22/2025
Riya Gandhi, MA
Some diagnoses can point toward broader type 2 immune involvement. Quiz yourself on which comorbidities may influence treatment decisions in AD.
Some diagnoses can point toward broader type 2 immune involvement. Quiz yourself on which comorbidities may influence treatment decisions in AD.
Some diagnoses can point toward...
07/22/2025
The Derm APP