Clinical Pearls
Topical Therapies for Pediatric AD
09/05/2025
A review of topical treatments for pediatric atopic dermatitis, from calcineurin inhibitors like pimecrolimus and tacrolimus to newer options like the PDE4 inhibitor crisaborole and the JAK inhibitor ruxolitinib. These therapies vary in molecular weight, systemic absorption, and efficacy in reducing inflammation and itch.
Peggy Vernon, RN, MA, CPNP, DCNP, FAANP, FSDNP, is a certified pediatric nurse practitioner, a psychiatric clinical nurse specialist, and a certified dermatology nurse practitioner.