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Crohn's Disease Learning Library

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Research Highlights
Guselkumab Demonstrates Efficacy and Safety in Moderate-to-Severe Crohn’s Disease
09/04/2025
Jessica Garlewicz
The study met all primary and multiplicity-controlled secondary endpoints, including clinical and endoscopic outcomes through 48 weeks.
The study met all primary and multiplicity-controlled secondary endpoints, including clinical and endoscopic outcomes through 48 weeks.
The study met all primary and...
09/04/2025
Advances in Inflammatory Bowel Disease Network
From Advances in Inflammatory Bowel Disease Network
News
Validation of a Simple Ultrasound Score for Crohn’s Disease
08/28/2025
Rebecca Mashaw
A multicenter study confirms the accuracy and reliability of a simplified ultrasound score for assessing Crohn’s disease activity.
A multicenter study confirms the accuracy and reliability of a simplified ultrasound score for assessing Crohn’s disease activity.
A multicenter study confirms the...
08/28/2025
Advances in Inflammatory Bowel Disease Network
From Advances in Inflammatory Bowel Disease Network
Shirley Cohen Mekelburg
Conference Coverage
Shirley Cohen-Mekelburg, MD, on Penetrating and Stricturing Crohn's Disease
08/25/2025
Dr Cohen-Mekelburg recaps the key takeaways from her presentation at the AIBD regional meeting in Detroit on managing penetrating and stricturing Crohn's disease and perianal disease.
Dr Cohen-Mekelburg recaps the key takeaways from her presentation at the AIBD regional meeting in Detroit on managing penetrating and stricturing Crohn's disease and perianal disease.
Dr Cohen-Mekelburg recaps the...
08/25/2025
Advances in Inflammatory Bowel Disease Network
From Advances in Inflammatory Bowel Disease Network
Clinical Pearls
Treating Bowel Obstruction in Crohn's Disease
06/10/2025
Kimberly Kearns, ANP-BC; Kimberly Orleck, ANP-BC; Abigail J. Meyers, BS; Angelina Collins, ANP-BC
In part 2 of this roundtable of APPs specializing in the care of patients with IBD, the participants review the diagnosis of intestinal obstruction in a patient with Crohn's disease and the steps to take to treat the condition.
In part 2 of this roundtable of APPs specializing in the care of patients with IBD, the participants review the diagnosis of intestinal obstruction in a patient with Crohn's disease and the steps to take to treat the condition.
In part 2 of this roundtable of...
06/10/2025
APP Institute Inflammatory Bowel Disease
David Rubin
Clinical Pearls
David Rubin, MD, on the GALAXI 2 and 3 Trials of Guselkumab in Crohn's Disease
05/06/2025
David T. Rubin, MD
Dr Rubin reviews the results of phase 3 trials of guselkumab for treatment of Crohn's disease among patients who are bionaive, bioexposed, and biointolerant or who failed to respond to biologics. 
Dr Rubin reviews the results of phase 3 trials of guselkumab for treatment of Crohn's disease among patients who are bionaive, bioexposed, and biointolerant or who failed to respond to biologics. 
Dr Rubin reviews the results of...
05/06/2025
APP Institute Inflammatory Bowel Disease
Marita Kametas
Rapid Refresh
Marita Kametas, MSN, on Disease Severity vs Activity in Crohn's Disease
04/21/2025
Marita Kametas, MSN-RN
APP Marita Kametas, MSN, from the University of Chicago, provides an overview of disease severity and disease activity in Crohn's disease.
APP Marita Kametas, MSN, from the University of Chicago, provides an overview of disease severity and disease activity in Crohn's disease.
APP Marita Kametas, MSN, from...
04/21/2025
APP Institute Inflammatory Bowel Disease
Clinical Pearls
Scoping Out the Issues in Crohn's Disease
04/18/2025
Kimberly Kearns, ANP-BC; Kimberly Orleck, ANP-BC; Angelina Collins, ANP-BC; Abigail J. Meyers, BS
At the inaugural APP Institute Inflammatory Bowel Disease, IBD specialist APPs Kimberly Kearns, Kim Orleck, Abigail Meyers, and Angelina Collins presented a case study illustrating the challenges of diagnosing and treating Crohn's disease.
At the inaugural APP Institute Inflammatory Bowel Disease, IBD specialist APPs Kimberly Kearns, Kim Orleck, Abigail Meyers, and Angelina Collins presented a case study illustrating the challenges of diagnosing and treating Crohn's disease.
At the inaugural APP Institute...
04/18/2025
APP Institute Inflammatory Bowel Disease
Jim Lewis
Clinical Pearls
James D. Lewis, MD, on Diet and Nutrition in Crohn's Disease
04/11/2025
James D. Lewis
Dr James D. Lewis recaps his presentation on using diet —including the Crohn's Disease Exclusion Diet, the Low FODmap Diet, and the Mediterranean diet—as an adjunct to medical therapy for Crohn's disease, and the potential for diet to perhaps...
Dr James D. Lewis recaps his presentation on using diet —including the Crohn's Disease Exclusion Diet, the Low FODmap Diet, and the Mediterranean diet—as an adjunct to medical therapy for Crohn's disease, and the potential for diet to perhaps...
Dr James D. Lewis recaps his...
04/11/2025
APP Institute Inflammatory Bowel Disease
Marla Dubinsky
Clinical Pearls
Marla Dubinsky, MD, on Risk Stratification in Crohn's Disease
04/11/2025
Marla C. Dubinsky, MD
Dr Dubinsky stresses that virtually all patients with Crohn's disease should be treated quickly after diagnosis with approved and effective therapies—which do not include 5-ASAs— to help prevent complications and change the natural history of...
Dr Dubinsky stresses that virtually all patients with Crohn's disease should be treated quickly after diagnosis with approved and effective therapies—which do not include 5-ASAs— to help prevent complications and change the natural history of...
Dr Dubinsky stresses that...
04/11/2025
APP Institute Inflammatory Bowel Disease
Ed Loftus
Clinical Pearls
Edward Loftus, MD, on Upper GI Crohn's Disease
01/07/2025
Edward V. Loftus, Jr., MD
Dr Loftus explains how Crohn's disease can affect the upper gastrointestinal system, from the mouth to the duodenum, and the options for treating this rare presentation.
Dr Loftus explains how Crohn's disease can affect the upper gastrointestinal system, from the mouth to the duodenum, and the options for treating this rare presentation.
Dr Loftus explains how Crohn's...
01/07/2025
Advances in Inflammatory Bowel Disease Network
From Advances in Inflammatory Bowel Disease Network
Clinical Pearls
Drs Miguel Regueiro and Corey Siegel Debate: Do All Patients With Crohn's Disease Need Advanced Therapy?
12/10/2024
The annual debate between Drs Regueiro and Siegel this year took on the topic of whether all patients newly diagnosed with Crohn's disease should be treated with advanced therapies from the beginning. Check out the video to see what each had...
The annual debate between Drs Regueiro and Siegel this year took on the topic of whether all patients newly diagnosed with Crohn's disease should be treated with advanced therapies from the beginning. Check out the video to see what each had...
The annual debate between Drs...
12/10/2024
APP Institute Inflammatory Bowel Disease

Clinical Pearls

David Rubin
Clinical Pearls
David Rubin, MD, on the GALAXI 2 and 3 Trials of Guselkumab in Crohn's Disease
05/06/2025
David T. Rubin, MD
Dr Rubin reviews the results of phase 3 trials of guselkumab for treatment of Crohn's disease among patients who are bionaive, bioexposed, and biointolerant or who failed to respond to biologics. 
Dr Rubin reviews the results of phase 3 trials of guselkumab for treatment of Crohn's disease among patients who are bionaive, bioexposed, and biointolerant or who failed to respond to biologics. 
Dr Rubin reviews the results of...
05/06/2025
APP Institute Inflammatory Bowel Disease
Jim Lewis
Clinical Pearls
James D. Lewis, MD, on Diet and Nutrition in Crohn's Disease
04/11/2025
James D. Lewis
Dr James D. Lewis recaps his presentation on using diet —including the Crohn's Disease Exclusion Diet, the Low FODmap Diet, and the Mediterranean diet—as an adjunct to medical therapy for Crohn's disease, and the potential for diet to perhaps...
Dr James D. Lewis recaps his presentation on using diet —including the Crohn's Disease Exclusion Diet, the Low FODmap Diet, and the Mediterranean diet—as an adjunct to medical therapy for Crohn's disease, and the potential for diet to perhaps...
Dr James D. Lewis recaps his...
04/11/2025
APP Institute Inflammatory Bowel Disease
Marla Dubinsky
Clinical Pearls
Marla Dubinsky, MD, on Risk Stratification in Crohn's Disease
04/11/2025
Marla C. Dubinsky, MD
Dr Dubinsky stresses that virtually all patients with Crohn's disease should be treated quickly after diagnosis with approved and effective therapies—which do not include 5-ASAs— to help prevent complications and change the natural history of...
Dr Dubinsky stresses that virtually all patients with Crohn's disease should be treated quickly after diagnosis with approved and effective therapies—which do not include 5-ASAs— to help prevent complications and change the natural history of...
Dr Dubinsky stresses that...
04/11/2025
APP Institute Inflammatory Bowel Disease
Conference Coverage
Jamie Brogan, APRN, on Extraintestinal Manifestations of IBD
07/31/2025
Jamie Brogan, APRN
Jamie Brogan, APRN, reviews her presentation on identifying and treating the most frequently seen extraintestinal manifestations among patients with inflammatory bowel disease.
Jamie Brogan, APRN, reviews her presentation on identifying and treating the most frequently seen extraintestinal manifestations among patients with inflammatory bowel disease.
Jamie Brogan, APRN, reviews her...
07/31/2025
Advances in Inflammatory Bowel Disease Network
David Rubin
Clinical Pearls
David Rubin, MD, on the GALAXI 2 and 3 Trials of Guselkumab in Crohn's Disease
05/06/2025
David T. Rubin, MD
Dr Rubin reviews the results of phase 3 trials of guselkumab for treatment of Crohn's disease among patients who are bionaive, bioexposed, and biointolerant or who failed to respond to biologics. 
Dr Rubin reviews the results of phase 3 trials of guselkumab for treatment of Crohn's disease among patients who are bionaive, bioexposed, and biointolerant or who failed to respond to biologics. 
Dr Rubin reviews the results of...
05/06/2025
APP Institute Inflammatory Bowel Disease
Jim Lewis
Clinical Pearls
James D. Lewis, MD, on Diet and Nutrition in Crohn's Disease
04/11/2025
James D. Lewis
Dr James D. Lewis recaps his presentation on using diet —including the Crohn's Disease Exclusion Diet, the Low FODmap Diet, and the Mediterranean diet—as an adjunct to medical therapy for Crohn's disease, and the potential for diet to perhaps...
Dr James D. Lewis recaps his presentation on using diet —including the Crohn's Disease Exclusion Diet, the Low FODmap Diet, and the Mediterranean diet—as an adjunct to medical therapy for Crohn's disease, and the potential for diet to perhaps...
Dr James D. Lewis recaps his...
04/11/2025
APP Institute Inflammatory Bowel Disease
Marla Dubinsky
Clinical Pearls
Marla Dubinsky, MD, on Risk Stratification in Crohn's Disease
04/11/2025
Marla C. Dubinsky, MD
Dr Dubinsky stresses that virtually all patients with Crohn's disease should be treated quickly after diagnosis with approved and effective therapies—which do not include 5-ASAs— to help prevent complications and change the natural history of...
Dr Dubinsky stresses that virtually all patients with Crohn's disease should be treated quickly after diagnosis with approved and effective therapies—which do not include 5-ASAs— to help prevent complications and change the natural history of...
Dr Dubinsky stresses that...
04/11/2025
APP Institute Inflammatory Bowel Disease
Uma Mahadevan, MD
Clinical Pearls
Caring for the Pregnant Patient With IBD
02/26/2024
Uma Mahadevan
Dr Uma Mahadevan discusses the key factors to consider when caring for patients with inflammatory bowel disease who are or who want to become pregnant.
Dr Uma Mahadevan discusses the key factors to consider when caring for patients with inflammatory bowel disease who are or who want to become pregnant.
Dr Uma Mahadevan discusses the...
02/26/2024
APP Institute Inflammatory Bowel Disease
David Rubin
Clinical Pearls
Dose Optimization of Anti-TNF Therapy for IBD
02/26/2024
Dr David Rubin provides a guideline for optimizing adalimumab and infliximab in treating patients with inflammatory bowel disease.
Dr David Rubin provides a guideline for optimizing adalimumab and infliximab in treating patients with inflammatory bowel disease.
Dr David Rubin provides a...
02/26/2024
APP Institute Inflammatory Bowel Disease
Laura Raffals
Clinical Pearls
Top Clinical Pearls for Managing Ulcerative Colitis
01/21/2023
Dr Laura Raffals from Mayo Clinic discusses her top clinical tips for ensuring proper diagnosis, treatment, monitoring, and management of patients with ulcerative colitis.
Dr Laura Raffals from Mayo Clinic discusses her top clinical tips for ensuring proper diagnosis, treatment, monitoring, and management of patients with ulcerative colitis.
Dr Laura Raffals from Mayo...
01/21/2023
APP Institute Inflammatory Bowel Disease

Rapid Refresh

Marita Kametas
Rapid Refresh
Marita Kametas, MSN, on Disease Severity vs Activity in Crohn's Disease
04/21/2025
Marita Kametas, MSN-RN
APP Marita Kametas, MSN, from the University of Chicago, provides an overview of disease severity and disease activity in Crohn's disease.
APP Marita Kametas, MSN, from the University of Chicago, provides an overview of disease severity and disease activity in Crohn's disease.
APP Marita Kametas, MSN, from...
04/21/2025
APP Institute Inflammatory Bowel Disease
Marita Kametas
Rapid Refresh
Marita Kametas, MSN, on Disease Severity vs Activity in Crohn's Disease
04/21/2025
Marita Kametas, MSN-RN
APP Marita Kametas, MSN, from the University of Chicago, provides an overview of disease severity and disease activity in Crohn's disease.
APP Marita Kametas, MSN, from the University of Chicago, provides an overview of disease severity and disease activity in Crohn's disease.
APP Marita Kametas, MSN, from...
04/21/2025
APP Institute Inflammatory Bowel Disease
Kim Kearns
Video
Kimberly Kearns, MS, APRN, on Diagnostics in IBD
07/01/2024
Kimberly Kearns, ANP-BC
Kimberly Kearns, MS, APN-BC, delves into the noninvasive and invasive diagnostic tools available to APPs working with patients who have or are suspected of having inflammatory bowel disease.
Kimberly Kearns, MS, APN-BC, delves into the noninvasive and invasive diagnostic tools available to APPs working with patients who have or are suspected of having inflammatory bowel disease.
Kimberly Kearns, MS, APN-BC,...
07/01/2024
APP Institute Inflammatory Bowel Disease
Marita Kametas
Rapid Refresh
Severity vs Activity in IBD
06/26/2024
Marita Kametas, MSN, APN, continues her tutorial on IBD with a review of the disease severity and disease activity, including how they differ and how they can be assessed.
Marita Kametas, MSN, APN, continues her tutorial on IBD with a review of the disease severity and disease activity, including how they differ and how they can be assessed.
Marita Kametas, MSN, APN,...
06/26/2024
APP Institute Inflammatory Bowel Disease
Marita Kametas
Rapid Refresh
UC or CD: What's the Difference?
06/26/2024
Marita Kametas, MSN, APN, from the University of Chicago, begins a series on the basics of inflammatory bowel disease, explaining the differences between ulcerative colitis and Crohn's disease.
Marita Kametas, MSN, APN, from the University of Chicago, begins a series on the basics of inflammatory bowel disease, explaining the differences between ulcerative colitis and Crohn's disease.
Marita Kametas, MSN, APN, from...
06/26/2024
APP Institute Inflammatory Bowel Disease

Perspectives

Erin Darguzas
APP Perspectives
The APP-MD Relationship
05/20/2025
Erin Darguzas, APN
Erin Darguzas, APN, from Northwestern Medicine in Chicago reviews how physician training culture and expectations are very different from APP training and onboarding and how this can affect expectations and the way APPs are incorporated into...
Erin Darguzas, APN, from Northwestern Medicine in Chicago reviews how physician training culture and expectations are very different from APP training and onboarding and how this can affect expectations and the way APPs are incorporated into...
Erin Darguzas, APN, from...
05/20/2025
APP Institute Inflammatory Bowel Disease
Marita Kametas
APP Perspectives
Welcome to the APP Institute Inflammatory Bowel Disease!
03/01/2024
Marita Kametas, MSN, APN, introduces the new APP Institute Inflammatory Bowel DIsease and gives a brief overview of the content offerings for advanced practice providers in the IBD field.
Marita Kametas, MSN, APN, introduces the new APP Institute Inflammatory Bowel DIsease and gives a brief overview of the content offerings for advanced practice providers in the IBD field.
Marita Kametas, MSN, APN,...
03/01/2024
APP Institute Inflammatory Bowel Disease
Kim Orleck
APP Perspectives
Tracking Productivity in IBD Care for APPs
02/26/2024
Kimberly Orleck reviews how much of an APP's work in an IBD practice may not be carefully tracked or compensated for, and how to
Kimberly Orleck reviews how much of an APP's work in an IBD practice may not be carefully tracked or compensated for, and how to
Kimberly Orleck reviews how much...
02/26/2024
APP Institute Inflammatory Bowel Disease
APP Institute Advances in Inflammatory Bowel Disease

The APP Institute is dedicated to educating and informing advanced practice providers on clinical topics and practical issues to support the profession and improve the quality of care for patients with inflammatory bowel disease (IBD).

The APP Institute | Advances in Inflammatory Bowel Disease is designed for Advanced Practice Providers who specialize in Inflammatory Bowel Diseases, to further their education and increase their knowledge to achieve better patient outcomes. Explore cutting-edge research, innovative treatment options, and new therapeutic methods, while remaining focused on the fundamental principles and terminology associated with IBD.

December 6-7, 2025 | Register Now

 

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