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Parkinson Disease Topic Center

Featured Article

News
12/20/2024
Lisa Kuhns, PhD, MD
Palliative care plays a critical role in improving the quality of life for patients with advanced Parkinson disease (PD) and their caregivers, yet it remains underutilized.
Palliative care plays a critical role in improving the quality of life for patients with advanced Parkinson disease (PD) and their caregivers, yet it remains underutilized.
Palliative care plays a critical...
12/20/2024
Annals of Long-Term Care
News
12/06/2024
Lisa Kuhns, PhD, MD
Patients with Parkinson disease (PD) and with a family history of the condition may experience slower disease progression and a lower risk of developing freezing of gait.
Patients with Parkinson disease (PD) and with a family history of the condition may experience slower disease progression and a lower risk of developing freezing of gait.
Patients with Parkinson disease...
12/06/2024
Annals of Long-Term Care
News
11/15/2024
Lisa Kuhns, PhD, MD
People with Parkinson disease (PD) and their care partners (CPs) face significant challenges affecting their health-related quality of life (HRQOL), with different PD symptoms impacting them as the disease progresses.
People with Parkinson disease (PD) and their care partners (CPs) face significant challenges affecting their health-related quality of life (HRQOL), with different PD symptoms impacting them as the disease progresses.
People with Parkinson disease...
11/15/2024
Annals of Long-Term Care
News
10/10/2024
Lisa Kuhns, PhD, MD
Depression in Parkinson disease (PD) is not just a consequence of motor symptoms but may be an early indicator of the disease, associated with increased mortality and dementia risk, according to a study published in the Journal of Neurology,...
Depression in Parkinson disease (PD) is not just a consequence of motor symptoms but may be an early indicator of the disease, associated with increased mortality and dementia risk, according to a study published in the Journal of Neurology,...
Depression in Parkinson disease...
10/10/2024
Annals of Long-Term Care
News
09/10/2024
Lisa Kuhns, PhD, MD
The Parkinson's Foundation has announced a $3 million investment in 33 research grants, marking a significant step forward in the battle against Parkinson disease and offering new hope for millions of patients worldwide, according to a press...
The Parkinson's Foundation has announced a $3 million investment in 33 research grants, marking a significant step forward in the battle against Parkinson disease and offering new hope for millions of patients worldwide, according to a press...
The Parkinson's Foundation has...
09/10/2024
Annals of Long-Term Care
News
08/27/2024
Jolynn Tumolo
Globus pallidus internus (GPi) activity in patients with Parkinson’s disease (PD) was strongly modulated by circadian rhythms, according to a study published in Nature Communications.
Globus pallidus internus (GPi) activity in patients with Parkinson’s disease (PD) was strongly modulated by circadian rhythms, according to a study published in Nature Communications.
Globus pallidus internus (GPi)...
08/27/2024
Annals of Long-Term Care
News
08/05/2024
Jolynn Tumolo
Approximately 15% of patients with Parkinson disease (PD) in a large international cohort had potentially actionable genetic variants, according to a study published in the journal Brain.
Approximately 15% of patients with Parkinson disease (PD) in a large international cohort had potentially actionable genetic variants, according to a study published in the journal Brain.
Approximately 15% of patients...
08/05/2024
Annals of Long-Term Care
News
07/23/2024
Grace Taylor, MS, MA
A study assessed the safety and effectiveness of staged bilateral MRI-guided focused ultrasound subthalamotomy (FUS-STN) to treat Parkinson Disease (PD).
A study assessed the safety and effectiveness of staged bilateral MRI-guided focused ultrasound subthalamotomy (FUS-STN) to treat Parkinson Disease (PD).
A study assessed the safety and...
07/23/2024
Annals of Long-Term Care
News
06/20/2024
Grace Taylor, MS, MA
Researchers developed a blood test using artificial intelligence (AI) to predict Parkinson disease up to 7 years.
Researchers developed a blood test using artificial intelligence (AI) to predict Parkinson disease up to 7 years.
Researchers developed a blood...
06/20/2024
Annals of Long-Term Care
News
06/06/2024
Jolynn Tumolo
The US Food and Drug Administration (FDA) granted the investigational cell therapy bemdaneprocel a Regenerative Medicine Advanced Therapy (RMAT) designation for the treatment of Parkinson disease (PD), announced bemdaneprocel developer...
The US Food and Drug Administration (FDA) granted the investigational cell therapy bemdaneprocel a Regenerative Medicine Advanced Therapy (RMAT) designation for the treatment of Parkinson disease (PD), announced bemdaneprocel developer...
The US Food and Drug...
06/06/2024
Annals of Long-Term Care
News
05/21/2024
Lisa Kuhns, PhD, MD
Environmental exposure to airborne manganese, beryllium, and nickel may increase the risk of Parkinson disease (PD), according to study results presented at the 2024 Annual Meeting of the American Academy of Neurology.
Environmental exposure to airborne manganese, beryllium, and nickel may increase the risk of Parkinson disease (PD), according to study results presented at the 2024 Annual Meeting of the American Academy of Neurology.
Environmental exposure to...
05/21/2024
Annals of Long-Term Care

Newsfeed

News
12/20/2024
Lisa Kuhns, PhD, MD
Palliative care plays a critical role in improving the quality of life for patients with advanced Parkinson disease (PD) and their caregivers, yet it remains underutilized.
Palliative care plays a critical role in improving the quality of life for patients with advanced Parkinson disease (PD) and their caregivers, yet it remains underutilized.
Palliative care plays a critical...
12/20/2024
Annals of Long-Term Care
News
12/06/2024
Lisa Kuhns, PhD, MD
Patients with Parkinson disease (PD) and with a family history of the condition may experience slower disease progression and a lower risk of developing freezing of gait.
Patients with Parkinson disease (PD) and with a family history of the condition may experience slower disease progression and a lower risk of developing freezing of gait.
Patients with Parkinson disease...
12/06/2024
Annals of Long-Term Care
News
11/15/2024
Lisa Kuhns, PhD, MD
People with Parkinson disease (PD) and their care partners (CPs) face significant challenges affecting their health-related quality of life (HRQOL), with different PD symptoms impacting them as the disease progresses.
People with Parkinson disease (PD) and their care partners (CPs) face significant challenges affecting their health-related quality of life (HRQOL), with different PD symptoms impacting them as the disease progresses.
People with Parkinson disease...
11/15/2024
Annals of Long-Term Care
News
10/10/2024
Lisa Kuhns, PhD, MD
Depression in Parkinson disease (PD) is not just a consequence of motor symptoms but may be an early indicator of the disease, associated with increased mortality and dementia risk, according to a study published in the Journal of Neurology,...
Depression in Parkinson disease (PD) is not just a consequence of motor symptoms but may be an early indicator of the disease, associated with increased mortality and dementia risk, according to a study published in the Journal of Neurology,...
Depression in Parkinson disease...
10/10/2024
Annals of Long-Term Care
News
09/10/2024
Lisa Kuhns, PhD, MD
The Parkinson's Foundation has announced a $3 million investment in 33 research grants, marking a significant step forward in the battle against Parkinson disease and offering new hope for millions of patients worldwide, according to a press...
The Parkinson's Foundation has announced a $3 million investment in 33 research grants, marking a significant step forward in the battle against Parkinson disease and offering new hope for millions of patients worldwide, according to a press...
The Parkinson's Foundation has...
09/10/2024
Annals of Long-Term Care
News
08/27/2024
Jolynn Tumolo
Globus pallidus internus (GPi) activity in patients with Parkinson’s disease (PD) was strongly modulated by circadian rhythms, according to a study published in Nature Communications.
Globus pallidus internus (GPi) activity in patients with Parkinson’s disease (PD) was strongly modulated by circadian rhythms, according to a study published in Nature Communications.
Globus pallidus internus (GPi)...
08/27/2024
Annals of Long-Term Care
News
08/05/2024
Jolynn Tumolo
Approximately 15% of patients with Parkinson disease (PD) in a large international cohort had potentially actionable genetic variants, according to a study published in the journal Brain.
Approximately 15% of patients with Parkinson disease (PD) in a large international cohort had potentially actionable genetic variants, according to a study published in the journal Brain.
Approximately 15% of patients...
08/05/2024
Annals of Long-Term Care
News
07/23/2024
Grace Taylor, MS, MA
A study assessed the safety and effectiveness of staged bilateral MRI-guided focused ultrasound subthalamotomy (FUS-STN) to treat Parkinson Disease (PD).
A study assessed the safety and effectiveness of staged bilateral MRI-guided focused ultrasound subthalamotomy (FUS-STN) to treat Parkinson Disease (PD).
A study assessed the safety and...
07/23/2024
Annals of Long-Term Care
News
06/20/2024
Grace Taylor, MS, MA
Researchers developed a blood test using artificial intelligence (AI) to predict Parkinson disease up to 7 years.
Researchers developed a blood test using artificial intelligence (AI) to predict Parkinson disease up to 7 years.
Researchers developed a blood...
06/20/2024
Annals of Long-Term Care
News
06/06/2024
Jolynn Tumolo
The US Food and Drug Administration (FDA) granted the investigational cell therapy bemdaneprocel a Regenerative Medicine Advanced Therapy (RMAT) designation for the treatment of Parkinson disease (PD), announced bemdaneprocel developer...
The US Food and Drug Administration (FDA) granted the investigational cell therapy bemdaneprocel a Regenerative Medicine Advanced Therapy (RMAT) designation for the treatment of Parkinson disease (PD), announced bemdaneprocel developer...
The US Food and Drug...
06/06/2024
Annals of Long-Term Care
News
12/17/2025
Lisa Kuhns, PhD, MD
Neuropsychiatric symptoms in Alzheimer disease are now widely viewed as core, treatable features of dementia rather than side effects, and experts say the field is shifting toward earlier recognition and more person-centered care, according...
Neuropsychiatric symptoms in Alzheimer disease are now widely viewed as core, treatable features of dementia rather than side effects, and experts say the field is shifting toward earlier recognition and more person-centered care, according...
Neuropsychiatric symptoms in...
12/17/2025
Annals of Long-Term Care
News
12/16/2025
Grace Taylor, MS, MA
Research published in JAMA Neurology links higher exposure to fine particulate air pollution (PM2.5) with more severe Alzheimer-related brain changes and faster cognitive decline in older adults.
Research published in JAMA Neurology links higher exposure to fine particulate air pollution (PM2.5) with more severe Alzheimer-related brain changes and faster cognitive decline in older adults.
Research published in JAMA...
12/16/2025
Annals of Long-Term Care
News
12/11/2025
Juliet Gallagher
A recent study highlights the expanding role of passive sensing technologies to assess subjective experiences—including agitation, sadness, and anhedonia—in persons living with Alzheimer disease and related dementias (AD/ADRD). As traditional...
A recent study highlights the expanding role of passive sensing technologies to assess subjective experiences—including agitation, sadness, and anhedonia—in persons living with Alzheimer disease and related dementias (AD/ADRD). As traditional...
A recent study highlights the...
12/11/2025
Annals of Long-Term Care
News
12/04/2025
Hannah Musick
A new Early Alzheimer’s Disease Patient Care Pathway outlines scalable, system-wide strategies to improve timely diagnosis, integrate emerging biomarkers and anti-amyloid therapies, and streamline care coordination across US health systems.
A new Early Alzheimer’s Disease Patient Care Pathway outlines scalable, system-wide strategies to improve timely diagnosis, integrate emerging biomarkers and anti-amyloid therapies, and streamline care coordination across US health systems.
A new Early Alzheimer’s Disease...
12/04/2025
Annals of Long-Term Care
News
11/26/2025
Grace Taylor, MS, MA
A randomized trial shows that treating restless legs syndrome with gabapentin enacarbil can significantly reduce nighttime agitation and improve sleep in older adults with Alzheimer disease–related dementia.
A randomized trial shows that treating restless legs syndrome with gabapentin enacarbil can significantly reduce nighttime agitation and improve sleep in older adults with Alzheimer disease–related dementia.
A randomized trial shows that...
11/26/2025
Annals of Long-Term Care
News
11/20/2025
Grace Taylor, MS, MA
A national survey reveals that widespread misunderstanding of agitation in Alzheimer dementia is leaving millions of US caregivers emotionally drained, isolated, and struggling without adequate clinical support.
A national survey reveals that widespread misunderstanding of agitation in Alzheimer dementia is leaving millions of US caregivers emotionally drained, isolated, and struggling without adequate clinical support.
A national survey reveals that...
11/20/2025
Annals of Long-Term Care
News
11/10/2025
Juliet Gallagher
A 2024–2025 review of U.S. state medical cannabis programs found that Alzheimer disease (AD) and agitation associated with dementia remain qualifying conditions in 19 of 38 states. Despite this widespread policy inclusion, AD-related...
A 2024–2025 review of U.S. state medical cannabis programs found that Alzheimer disease (AD) and agitation associated with dementia remain qualifying conditions in 19 of 38 states. Despite this widespread policy inclusion, AD-related...
A 2024–2025 review of U.S. state...
11/10/2025
Annals of Long-Term Care
News
11/07/2025
Hannah Musick
A US caregiver survey found that nearly all individuals with Alzheimer disease exhibit agitated behaviors, which are strongly linked to increased caregiver burden, anxiety, depression, and reduced work productivity.
A US caregiver survey found that nearly all individuals with Alzheimer disease exhibit agitated behaviors, which are strongly linked to increased caregiver burden, anxiety, depression, and reduced work productivity.
A US caregiver survey found that...
11/07/2025
Annals of Long-Term Care
News
11/07/2025
Hannah Musick
A US caregiver survey found that nearly all individuals with Alzheimer disease exhibit agitated behaviors, which are strongly linked to increased caregiver burden, anxiety, depression, and reduced work productivity.
A US caregiver survey found that nearly all individuals with Alzheimer disease exhibit agitated behaviors, which are strongly linked to increased caregiver burden, anxiety, depression, and reduced work productivity.
A US caregiver survey found that...
11/07/2025
Annals of Long-Term Care
News
10/30/2025
Grace Taylor, MS, MA
A pooled analysis finds that 2 or 3 mg/day of brexpiprazole consistently reduces agitation symptoms across nearly all subgroups of patients with Alzheimer dementia.
A pooled analysis finds that 2 or 3 mg/day of brexpiprazole consistently reduces agitation symptoms across nearly all subgroups of patients with Alzheimer dementia.
A pooled analysis finds that 2...
10/30/2025
Annals of Long-Term Care

Insights

Headshot of Dr Ruth Schneider on a blue background underneath the PopHealth Perspectives logo.
Podcasts
06/29/2021
Julie Gould; Maria Asimopoulos
Ruth Schneider, MD, assistant professor and director, Huntington’s Disease Society of America Center of Excellence, University of Rochester, discusses her recent research that examined patient outcomes and responses to buspirone in the...
Ruth Schneider, MD, assistant professor and director, Huntington’s Disease Society of America Center of Excellence, University of Rochester, discusses her recent research that examined patient outcomes and responses to buspirone in the...
Ruth Schneider, MD, assistant...
06/29/2021
Annals of Long-Term Care
Videos
02/18/2021
Maria C Ospina, MD, movement disorder neurologist, discusses how physicians can ensure they receive all of the information needed to unlock patterns of Parkinson disease among their patients, and breaks down treatment options for OFF episodes...
Maria C Ospina, MD, movement disorder neurologist, discusses how physicians can ensure they receive all of the information needed to unlock patterns of Parkinson disease among their patients, and breaks down treatment options for OFF episodes...
Maria C Ospina, MD, movement...
02/18/2021
Annals of Long-Term Care